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2015 Journal Article Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolismMartinez, Verónica S., Buchsteiner, Maria, Gray, Peter, Nielsen, Lars K. and Quek, Lake-Ee (2015). Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism. Metabolic Engineering Communications, 2, 46-57. doi: 10.1016/j.meteno.2015.06.001 |
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2015 Journal Article Systems analysis of methylerythritol-phosphate pathway flux in E. coli: Insights into the role of oxidative stress and the validity of lycopene as an isoprenoid reporter metaboliteBongers, Mareike, Chrysanthopoulos, Panagiotis K., Behrendorff, James B.Y.H., Hodson, Mark P., Vickers, Claudia E. and Nielsen, Lars K. (2015). Systems analysis of methylerythritol-phosphate pathway flux in E. coli: Insights into the role of oxidative stress and the validity of lycopene as an isoprenoid reporter metabolite. Microbial Cell Factories, 14 (1) 193, 193. doi: 10.1186/s12934-015-0381-7 |
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2015 Journal Article Filling the void: allogeneic myeloid cells for transplantationSchwaber, Jessica L., Brunck, Marion E., Levesque, Jean-Pierre and Nielsen, Lars K. (2015). Filling the void: allogeneic myeloid cells for transplantation. Current Opinion in Hematology, 23 (1), 72-77. doi: 10.1097/MOH.0000000000000205 |
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2015 Other Outputs A unique model platform for C4 plant systems and synthetic biologyNielsen, Lars (2015). A unique model platform for C4 plant systems and synthetic biology. Alexandria, Virginia, United States: Defense Technical Information Center. |
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2015 Journal Article Do genome-scale models need exact solvers or clearer standards?Ebrahim, Ali, Almaas, Eivind, Bauer, Eugen, Bordbar, Aarash, Burgard, Anthony P., Chang, Roger L., Draeger, Andreas, Famili, Iman, Feist, Adam M., Fleming, Ronan M. T., Fong, Stephen S., Hatzimanikatis, Vassily, Herrgard, Markus J., Holder, Allen, Hucka, Michael, Hyduke, Daniel, Jamshidi, Neema, Lee, Sang Yup, Le Novere, Nicolas, Lerman, Joshua A., Lewis, Nathan E., Ma, Ding, Mahadevan, Radhakrishnan, Maranas, Costas, Nagarajan, Harish, Navid, Ali, Nielsen, Jens, Nielsen, Lars K., Nogales, Juan ... Thiele, Ines (2015). Do genome-scale models need exact solvers or clearer standards?. Molecular Systems Biology, 11 (10) 831, 831. doi: 10.15252/msb.20156157 |
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2015 Journal Article A liquid chromatography-tandem mass spectrometry-based investigation of the lamellar interstitial metabolome in healthy horses and during experimental laminitis inductionMedina-Torres, C. E., van Eps, A. W., Nielsen, L. K. and Hodson, M. P. (2015). A liquid chromatography-tandem mass spectrometry-based investigation of the lamellar interstitial metabolome in healthy horses and during experimental laminitis induction. Veterinary Journal, 206 (2), 161-169. doi: 10.1016/j.tvjl.2015.07.031 |
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2015 Journal Article Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditionsLim, SooA, Marcellin, Esteban, Jacob, Shana and Nielsen, Lars K. (2015). Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditions. Journal of Proteomics, 126, 24-33. doi: 10.1016/j.jprot.2015.05.021 |
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2015 Journal Article Controlling heterologous gene expression in yeast cell factories on different carbon substrates and across the diauxic shift: a comparison of yeast promoter activitiesPeng, Bingyin, Williams, Thomas C., Henry, Matthew, Nielsen, Lars K. and Vickers, Claudia E. (2015). Controlling heterologous gene expression in yeast cell factories on different carbon substrates and across the diauxic shift: a comparison of yeast promoter activities. Microbial Cell Factories, 14 (1) 91, 1-11. doi: 10.1186/s12934-015-0278-5 |
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2015 Journal Article Intracellular trafficking of baculovirus particles: A quantitative study of the hearNPV/HzAm1 cell and AcMNPV/sf9 cell systemsMatindoost, Leila, Nielsen, Lars K and Reid, Steve (2015). Intracellular trafficking of baculovirus particles: A quantitative study of the hearNPV/HzAm1 cell and AcMNPV/sf9 cell systems. Viruses, 7 (5), 2288-2307. doi: 10.3390/v7052288 |
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2015 Journal Article Evolutionary engineering improves tolerance for replacement jet fuels in Saccharomyces cerevisiaeBrennan, Timothy C. R., Williams, Thomas C., Schulz, Benjamin L., Palfreyman, Robin W., Kroemer, Jens O. and Nielsen, Lars K. (2015). Evolutionary engineering improves tolerance for replacement jet fuels in Saccharomyces cerevisiae. Applied and Environmental Microbiology, 81 (10), 3316-3325. doi: 10.1128/AEM.04144-14 |
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2015 Journal Article Quorum-sensing linked RNA interference for dynamic metabolic pathway control in Saccharomyces cerevisiaeWilliams, T. C., Averesch, N. J. H., Winter, G., Plan, M. R., Vickers, C. E., Nielsen, L. K. and Kromer, J. O. (2015). Quorum-sensing linked RNA interference for dynamic metabolic pathway control in Saccharomyces cerevisiae. Metabolic Engineering, 29, 124-134. doi: 10.1016/j.ymben.2015.03.008 |
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2015 Journal Article A general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactionsSaa, Pedro and Nielsen, Lars K. (2015). A general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactions. PLoS Computational Biology, 11 (4) e1004195, 1-25. doi: 10.1371/journal.pcbi.1004195 |
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2015 Journal Article Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiaeWilliams, Thomas C., Espinosa, Monica I., Nielsen, Lars K. and Vickers, Claudia E. (2015). Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiae. Microbial Cell Factories, 14 (43) 43, 1-10. doi: 10.1186/s12934-015-0223-7 |
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2015 Journal Article Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencingClark, Michael B., Mercer, Tim R., Bussotti, Giovanni, Leonardi, Tommaso, Haynes, Katelin R., Crawford, Joanna, Brunck, Marion E., Cao, Kim-Anh Le, Thomas, Gethin P., Chen, Wendy Y., Taft, Ryan J., Nielsen, Lars K., Enright, Anton J., Mattick, John S. and Dinger, Marcel E. (2015). Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. Nature Methods, 12 (4), 339-342. doi: 10.1038/nmeth.3321 |
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2015 Journal Article High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesisOrellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015). High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 (2), 609-618. doi: 10.1021/pr501027c |
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2015 Journal Article Genome-wide discovery of human splicing branchpointsMercer, Tim R., Clark, Michael B., Anderson, Stacey B., Brunck, Marion E., Haerty, Wilifried, Crawford, Joanna, Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E. and Mattick, John S. (2015). Genome-wide discovery of human splicing branchpoints. Genome Research, 25 (2), 290-303. doi: 10.1101/gr.182899.114 |
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2015 Journal Article A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systemsde Oliveira Dal'molin, Cristiana Gomes, Quek, Lake-Ee, Saa, Pedro A. and Nielsen, Lars K. (2015). A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systems. Frontiers in Plant Science, 6 (JAN) 4, 4.1-4.12. doi: 10.3389/fpls.2015.00004 |
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2015 Conference Publication A systems platform for the characterization and repurposing of Clostridium autoethanogenum, a model, acetogenic, gas-fermenting microbeMarcellin, Esteban, Behrendorff, James, Brown, Steve, Dassanayake, Asela, Walker, David, DeTissera, Sashini, Segovia, Simon, Palfreyman, Robin W., Daniell, James, Reynoso, Vini R, Licona-Cassani, Cuauhtemoc, Quek, Lake-ee, Speight, Robert, Hodson, Mark P., Nielsen, Lars K., Mitchell, Wayne P., Köpke, Michael and Simpson, Sean D. (2015). A systems platform for the characterization and repurposing of Clostridium autoethanogenum, a model, acetogenic, gas-fermenting microbe. International Conference on Systems Biology , ICSB, Singapore, Singapore, 23-26 November 2015. |
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2015 Conference Publication 1,5-Anhydroglucitol, the most discriminatory metabolomic marker measured by Gas Chromatography-Mass Spectrometry in adolescents with Type 1 Diabetes compared to control subjects - high correlation with Glycomark assayConwell, Louise S., Hodson, Mark P., Chrysanthopoulos, Panagiotis K., Greer, Ristan M., Nielsen, Lars K., Cardinal, John W., Sanders, L., Gous, R. and Baskerville, Tracey (2015). 1,5-Anhydroglucitol, the most discriminatory metabolomic marker measured by Gas Chromatography-Mass Spectrometry in adolescents with Type 1 Diabetes compared to control subjects - high correlation with Glycomark assay. International Society of Paediatric and Adolescent Diabetes / Australasian Paediatric Endocrine Group Annual Scientific Meeting, Brisbane, QLD, Australia, October 2015. |
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2015 Journal Article Editorial: On the cusp of rational CHO cell engineeringNielsen, Lars and Borth, Nicole (2015). Editorial: On the cusp of rational CHO cell engineering. Biotechnology Journal, 10 (7), 929-930. doi: 10.1002/biot.201500375 |
