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2014

Journal Article

The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon

Steen, Jennifer A., Bohlke, Nina, Vickers, Claudia E. and Nielsen, Lars K. (2014). The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon. PLoS One, 9 (2) e88688, e88688.1-e88688.10. doi: 10.1371/journal.pone.0088688

The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon

2014

Book Chapter

Plant genome-scale modeling and implementation

Dal'Molin, Cristiana G. O., Quek, Lake-Ee, Palfreyman, Robin W. and Nielsen, Lars K. (2014). Plant genome-scale modeling and implementation. Plant metabolic flux analysis: methods and protocols. (pp. 317-332) edited by DieuaideNoubhani, M and Alonso, AP. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-688-7_19

Plant genome-scale modeling and implementation

2014

Book Chapter

NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network

Martínez, Veronica Sofía and Nielsen, LK (2014). NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network. Metabolic Flux Analysis: Methods and Protocols. (pp. 65-78) edited by Jens O. Kromer, Lars K. Nielsen and Lars M. Blank. New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-1170-7_4

NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network

2014

Journal Article

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq

Mercer, Tim R., Clark, Michael B., Crawford, Joanna, Brunck, Marion E., Gerhardt, Daniel J., Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E. and Mattick, John S. (2014). Targeted sequencing for gene discovery and quantification using RNA CaptureSeq. Nature Protocols, 9 (5), 989-1009. doi: 10.1038/nprot.2014.058

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq

2014

Journal Article

The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality

Matindoost, Leila, Hu, Hao, Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2014). The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality. Archives of Virology, 159 (1), 91-102. doi: 10.1007/s00705-013-1789-1

The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality

2014

Book Chapter

Steady-State 13C Fluxomics Using OpenFLUX

Quek, Lake-Ee and Nielsen, Lars K. (2014). Steady-State 13C Fluxomics Using OpenFLUX. Metabolic Flux Analysis: Methods and Protocols. (pp. 209-224) edited by Jens O. Kromer, Lars K. Nielsen and Lars M. Blank. New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-1170-7_13

Steady-State 13C Fluxomics Using OpenFLUX

2014

Conference Publication

Towards a large integrated model of signal transduction and gene regulation events in mammalian cells

Fearnley, Liam G., Ragan, Mark A. and Nielsen, Lars K. (2014). Towards a large integrated model of signal transduction and gene regulation events in mammalian cells. BIOINFORMATICS 2014: 5th International Conference on Bioinformatics Models, Methods and Algorithms, Angers, Loire Valley, France, 3-6 March 2014. London, UK: SciTePress. doi: 10.5220/0004739601170122

Towards a large integrated model of signal transduction and gene regulation events in mammalian cells

2014

Journal Article

A transient disruption of fibroblastic transcriptional regulatory network facilitates trans-differentiation

Tomaru, Yasuhiro, Hasegawa, Ryota, Suzuki, Takahiro, Sato, Taiji, Kubosaki, Atsutaka, Suzuki, Masanori, Kawaji, Hideya, Forrest, Alistair R. R., Hayashizaki, Yoshihide, FANTOM Consortium, Shin, Jay W., Suzuki, Harukazu, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Wolvetang, Ernst, Hitchens, Kelly, Fearnley, Liam, Kenna, Tony, Blumenthal, Antje, Briggs, James, Ovchinnikov, Dmitry, Le Cao, Kim-Anh, Mason, Elizabeth and Nielsen, Lars (2014). A transient disruption of fibroblastic transcriptional regulatory network facilitates trans-differentiation. Nucleic Acids Research, 42 (14), 8905-8913. doi: 10.1093/nar/gku567

A transient disruption of fibroblastic transcriptional regulatory network facilitates trans-differentiation

2014

Conference Publication

Developing an integrated systems and synthetic biology platform for gas fermentation

Marcellin, Esteban, Segovia, Simon, De Tissera, Sashini, Mitchell, Wayne, Kopke, Michael and Nielsen, Lars K. (2014). Developing an integrated systems and synthetic biology platform for gas fermentation. Metabolic Engineering X, Vancouver, BC, Canada, 15-19 June 2014.

Developing an integrated systems and synthetic biology platform for gas fermentation

2014

Book Chapter

Customization of 13C-MFA Strategy According to Cell Culture System

Quek, Lake-Ee and Nielsen, Lars K. (2014). Customization of 13C-MFA Strategy According to Cell Culture System. Metabolic Flux Analysis: Methods and Protocols. (pp. 81-90) edited by Jens O. Kromer, Lars K. Nielsen and Lars M. Blank. New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-1170-7_5

Customization of 13C-MFA Strategy According to Cell Culture System

2014

Journal Article

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

Grison, Alice, Zucchelli, Silvia, Urzi, Alice, Zamparo, Ilaria, Lazarevic, Dejan, Pascarella, Giovanni, Roncaglia, Paola, Giorgetti, Alejandro, Garcia-Esparcia, Paula, Vlachouli, Christina, Simone, Roberto, Persichetti, Francesca, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Carloni, Paolo, Ferrer, Isidro, Lodovichi, Claudia, Plessy, Charles, the FANTOM Consortium, Carninci, Piero, Gustincich, Stefano, Beckhouse, Anthony, Briggs, James, Hitchens, Kelly, Kenna, Tony, Ovchinnikov, Dmitry, Vijayan, Dipti, Wells, Christine, Wolvetang, Ernst ... Nielsen, Lars (2014). Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules. BMC Genomics, 15 (1) 729. doi: 10.1186/1471-2164-15-729

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

2014

Journal Article

A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators

Hurst, Laurence D., Sachenkova, Oxana, Daub, Carsten, Forrest, Alistair R. R., the FANTOM consortium, Huminiecki, Lukasz, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Wolvetang, Ernst, Hitchens, Kelly, Kenna, Tony, Blumenthal, Antje, Briggs, James, Ovchinnikov, Dmitry, Fearnley, Liam, Le Cao, Kim-Anh, Mason, Elizabeth and Nielsen, Lars (2014). A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators. Genome Biology, 15 (7) 413. doi: 10.1186/s13059-014-0413-3

A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators

2014

Journal Article

Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor

Navone, Laura, Casati, Paula, Licona-Cassani, Cuauhtémoc, Marcellin, Esteban, Nielsen, Lars K., Rodriguez, Eduardo and Gramajo, Hugo (2014). Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor. Applied Microbiology and Biotechnology., 98 (1), 351-360. doi: 10.1007/s00253-013-5372-1

Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor

2013

Journal Article

Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane

Petrasovits, Lars A., McQualter, Richard B., Gebbie, Leigh K., Blackman, Deborah M., Nielsen, Lars K. and Brumbley, Stevens M. (2013). Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane. Plant Biotechnology Journal, 11 (9), 1146-1151. doi: 10.1111/pbi.12109

Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane

2013

Journal Article

Genome scale transcriptomics of baculovirus-insect interactions

Nguyen,Quan, Nielsen, Lars K. and Reid, Steven (2013). Genome scale transcriptomics of baculovirus-insect interactions. Viruses, 5 (11), 2721-2747. doi: 10.3390/v5112721

Genome scale transcriptomics of baculovirus-insect interactions

2013

Journal Article

Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae

Vickers C.E., Bydder S.F., Zhou Y. and Nielsen L.K. (2013). Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae. Microbial Cell Factories, 12 (96) 96, 96.1-96.11. doi: 10.1186/1475-2859-12-96

Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae

2013

Journal Article

Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach

Marcellin, Esteban, Licona-Cassani, Cuauhtemoc, Mercer, Tim R., Palfreyman, Robin W. and Nielsen, Lars K. (2013). Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach. BMC Genomics, 14: Provisional (699) 699, 1-18. doi: 10.1186/1471-2164-14-699

Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach

2013

Journal Article

Enhanced gametocyte formation in erythrocyte progenitor cells: A site-specific adaptation by Plasmodium falciparum

Peatey, Christopher L., Watson, Jolanta A., Trenholme, Katharine R., Brown, Christopher L., Nielson, Lars, Guenther, Marko, Timmins, Nicholas, Watson, Gregory S. and Gardiner, Donald L. (2013). Enhanced gametocyte formation in erythrocyte progenitor cells: A site-specific adaptation by Plasmodium falciparum. The Journal of Infectious Diseases, 208 (7), 1170-1174. doi: 10.1093/infdis/jit309

Enhanced gametocyte formation in erythrocyte progenitor cells: A site-specific adaptation by Plasmodium falciparum

2013

Journal Article

Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus

Nguyen, Quan, Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2013). Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus. Virology, 444 (1-2), 158-170. doi: 10.1016/j.virol.2013.06.004

Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus

2013

Journal Article

2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis

Behrendorff, James B. Y. H., Vickers, Claudia E., Chrysanthopoulos, Panagiotis and Nielsen, Lars K. (2013). 2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis. Microbial Cell Factories, 12 (76) 76, 1-11. doi: 10.1186/1475-2859-12-76

2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis