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2012 Journal Article A multi-omics analysis of recombinant protein production in Hek293 cellsDietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Gray, Peter and Nielsen, Lars K. (2012). A multi-omics analysis of recombinant protein production in Hek293 cells. Plos One, 7 (8) e43394, e43394.1-e43394.15. doi: 10.1371/journal.pone.0043394 |
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2012 Journal Article Suspension culture titration: A simple method for measuring baculovirus titersMatindoost, Leila, Chan, Leslie C. L., Qi, Ying Mei, Nielsen, Lars K. and Reid, Steven (2012). Suspension culture titration: A simple method for measuring baculovirus titers. Journal of Virological Methods, 183 (2), 201-209. doi: 10.1016/j.jviromet.2012.04.015 |
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2012 Journal Article PATHLOGIC-S: A scalable boolean framework for modelling cellular signallingFearnley, Liam G. and Nielsen, Lars K. (2012). PATHLOGIC-S: A scalable boolean framework for modelling cellular signalling. PLoS One, 7 (8 Article. No.e41977) e41977, e41977. doi: 10.1371/journal.pone.0041977 |
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2012 Journal Article Metabolite profiling of CHO cells with different growth characteristicsDietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Jacob, Shana S., Gray, Peter and Nielsen, Lars K. (2012). Metabolite profiling of CHO cells with different growth characteristics. Biotechnology and Bioengineering, 109 (6), 1404-1414. doi: 10.1002/bit.24496 |
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2012 Journal Article Enhanced polyhydroxybutyrate production in transgenic sugarcanePetrasovits, Lars A., Zhao, Lihan, McQualter, Richard B., Snell, Kristi D., Somleva, Maria N., Patterson, Nii A., Nielsen, Lars K. and Brumbley, Stevens M (2012). Enhanced polyhydroxybutyrate production in transgenic sugarcane. Plant Biotechnology Journal, 10 (5), 569-578. doi: 10.1111/j.1467-7652.2012.00686.x |
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2012 Journal Article Sucrose mobilisation in sugarcane stalk induced by heterotrophic axillary bud growthO’Neill, Brian P., Purnell, Matthew P., Anderson, David J., Nielsen, Lars K. and Brumbley, Stevens M. (2012). Sucrose mobilisation in sugarcane stalk induced by heterotrophic axillary bud growth. Tropical Plant Biology, 5 (2), 173-182. doi: 10.1007/s12042-012-9097-6 |
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2012 Journal Article Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactionsNguyen, Quan, Palfreyman, Robin W., Chan, Leslie C. L., Reid, Steven and Nielsen, Lars K. (2012). Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions. PLoS One, 7 (5) e36324, e36324.1-e36324.15. doi: 10.1371/journal.pone.0036324 |
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2012 Journal Article Improving the robustness of a low-cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor-based statistical optimization routineHuynh, Hoai T., Chan, Leslie C. L., Tran, Trinh T. B., Nielsen, Lars K. and Reid, Steven (2012). Improving the robustness of a low-cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor-based statistical optimization routine. Biotechnology Progress, 28 (3), 788-802. doi: 10.1002/btpr.1529 |
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2012 Journal Article Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cellsTran, Trinh T.B., Dietmair, Stefanie, Chan, Leslie C.L., Huynh, Hoai T., Nielsen, Lars K. and Reid, Steven (2012). Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cells. Methods, 56 (3), 396-407. doi: 10.1016/j.ymeth.2011.11.009 |
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2012 Book Chapter Large scale ex vivo manufacture of blood cellsTimmins, Nicholas E. and Nielsen, Lars K. (2012). Large scale ex vivo manufacture of blood cells. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 557-571) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer. |
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2012 Journal Article METABOLIC PATHWAY ENGINEERING FOR HYALURONIC ACID PRODUCTIONMarcellin, Esteban, Chen, Wendy Y. and Nielsen, Lars K. (2012). METABOLIC PATHWAY ENGINEERING FOR HYALURONIC ACID PRODUCTION. Carbohydrate-Modifying Biocatalysts, 571-584. |
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2012 Conference Publication Major adjustments in metabolic flux occur to accommodate PHB production in sugarcaneMcQualter, Richard, Gebbie, Leigh, Dal'Molin, Cristiana G.d., Petrasovits, Lars, Snell, K. D., Nielsen, Lars K. and Brumbley, Stevens (2012). Major adjustments in metabolic flux occur to accommodate PHB production in sugarcane. The 13th International Symposium on Biopolymers (ISBP 2012), Cairns, Australia, 7-10 October. |
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2012 Journal Article Mammalian cells as biopharmaceutical production hosts in the age of omicsDietmair, Stefanie, Nielsen, Lars K. and Timmins, Nicholas E. (2012). Mammalian cells as biopharmaceutical production hosts in the age of omics. Biotechnology Journal, 7 (1), 75-89. doi: 10.1002/biot.201100369 |
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2012 Journal Article Bioreactor for blood product productionDoran, Michael R., Aird, Ian Alexander, Marturana, Flavia, Timmins, Nicholas, Atkinson, Kerry and Nielsen, Lars K. (2012). Bioreactor for blood product production. Cell Transplantation, 21 (6), 1235-1244. doi: 10.3727/096368911X627363 |
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2012 Conference Publication Metabolomic Analysis of CHO Cultures with Different Growth Characteristics - Development of a Metabolite Extraction Protocol for Suspension Adapted Mammalian CellsDietmair, Stefanie, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Gray, Peter P., Kromer, Jens O. and Nielsen, Lars K. (2012). Metabolomic Analysis of CHO Cultures with Different Growth Characteristics - Development of a Metabolite Extraction Protocol for Suspension Adapted Mammalian Cells. 21st Annual Meeting of the European-Society-for-Animal-Cell-Technology (ESACT), Dublin Ireland, Jun 07-10, 2009. DORDRECHT: SPRINGER. doi: 10.1007/978-94-007-0884-6_6 |
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2012 Book Chapter Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cellsDietmair, Stefanie, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Gray, Peter P., Krömer, Jens O. and Nielsen, Lars K. (2012). Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 37-41) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer. |
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2012 Book Chapter Metabolic pathway engineering for hyaluronic acid productionMarcellin, Esteban, Chen, Wendy Y. and Nielsen, Lars K. (2012). Metabolic pathway engineering for hyaluronic acid production. Carbohydrate modifying biocatalysts. (pp. 571-584) edited by Peter Grundwald. Singapore: Pan Stanford Publishing. doi: 10.4032/9789814303484 |
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2012 Conference Publication Dynamic analysis of Saccharopolyspora erythraea life cycle in bioreactors; a systems approachLicona Cassani, Cuauthemoc, Marcellin Saldana, Esteban Stefane and Nielsen, Lars K. (2012). Dynamic analysis of Saccharopolyspora erythraea life cycle in bioreactors; a systems approach. Actinobacteria within soil, Munster, Germany, 25-28 October 2012. |
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2012 Conference Publication Large Scale Ex Vivo Manufacture of Blood CellsTimmins, Nicholas E. and Nielsen, Lars K. (2012). Large Scale Ex Vivo Manufacture of Blood Cells. 21st Annual Meeting of the European-Society-for-Animal-Cell-Technology (ESACT), Dublin Ireland, Jun 07-10, 2009. DORDRECHT: SPRINGER. doi: 10.1007/978-94-007-0884-6_92 |
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2011 Journal Article AlgaGEM - A genome-scale metabolic reconstruction of Algae based on Chlamydomonas reinhardtii genomeDal'Molin, Cristiana Gomes de Oliveira, Quek, Lake-Ee, Palfreyman, Robin W. and Nielsen, Lars K. (2011). AlgaGEM - A genome-scale metabolic reconstruction of Algae based on Chlamydomonas reinhardtii genome. BMC Genomics, 12 (S4), s5.1-s5.10. doi: 10.1186/1471-2164-12-S4-S5 |
