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2012

Journal Article

Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae

Brennan, Timothy C. R., Turner, Christopher D., Kroemer, Jens O. and Nielsen, Lars K. (2012). Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae. Biotechnology and Bioengineering, 109 (10), 2513-2522. doi: 10.1002/bit.24536

Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae

2012

Journal Article

A transferable sucrose utilization approach for non-sucrose-utilizing Escherichia coli strains

Bruschi, Michele, Boyes, Simon J., Sugiarto, Haryadi, Nielsen, Lars K. and Vickers, Claudia E. (2012). A transferable sucrose utilization approach for non-sucrose-utilizing Escherichia coli strains. Biotechnology Advances, 30 (5), 1001-1010. doi: 10.1016/j.biotechadv.2011.08.019

A transferable sucrose utilization approach for non-sucrose-utilizing Escherichia coli strains

2012

Journal Article

Engineering and adaptive evolution of Escherichia coli for D-lactate fermentation reveals GatC as a xylose transporter

Utrilla, Jose, Licona-Cassani, Cuauhtemoc, Marcellin, Esteban, Gosset, Guillermo, Nielsen, Lars K. and Martinez, Alfredo (2012). Engineering and adaptive evolution of Escherichia coli for D-lactate fermentation reveals GatC as a xylose transporter. Metabolic Engineering, 14 (5), 469-476. doi: 10.1016/j.ymben.2012.07.007

Engineering and adaptive evolution of Escherichia coli for D-lactate fermentation reveals GatC as a xylose transporter

2012

Journal Article

Suspension culture titration: A simple method for measuring baculovirus titers

Matindoost, Leila, Chan, Leslie C. L., Qi, Ying Mei, Nielsen, Lars K. and Reid, Steven (2012). Suspension culture titration: A simple method for measuring baculovirus titers. Journal of Virological Methods, 183 (2), 201-209. doi: 10.1016/j.jviromet.2012.04.015

Suspension culture titration: A simple method for measuring baculovirus titers

2012

Journal Article

PATHLOGIC-S: A scalable boolean framework for modelling cellular signalling

Fearnley, Liam G. and Nielsen, Lars K. (2012). PATHLOGIC-S: A scalable boolean framework for modelling cellular signalling. PLoS One, 7 (8 Article. No.e41977) e41977, e41977. doi: 10.1371/journal.pone.0041977

PATHLOGIC-S: A scalable boolean framework for modelling cellular signalling

2012

Journal Article

A multi-omics analysis of recombinant protein production in Hek293 cells

Dietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Gray, Peter and Nielsen, Lars K. (2012). A multi-omics analysis of recombinant protein production in Hek293 cells. Plos One, 7 (8) e43394, e43394.1-e43394.15. doi: 10.1371/journal.pone.0043394

A multi-omics analysis of recombinant protein production in Hek293 cells

2012

Journal Article

Sucrose mobilisation in sugarcane stalk induced by heterotrophic axillary bud growth

O’Neill, Brian P., Purnell, Matthew P., Anderson, David J., Nielsen, Lars K. and Brumbley, Stevens M. (2012). Sucrose mobilisation in sugarcane stalk induced by heterotrophic axillary bud growth. Tropical Plant Biology, 5 (2), 173-182. doi: 10.1007/s12042-012-9097-6

Sucrose mobilisation in sugarcane stalk induced by heterotrophic axillary bud growth

2012

Journal Article

Metabolite profiling of CHO cells with different growth characteristics

Dietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Jacob, Shana S., Gray, Peter and Nielsen, Lars K. (2012). Metabolite profiling of CHO cells with different growth characteristics. Biotechnology and Bioengineering, 109 (6), 1404-1414. doi: 10.1002/bit.24496

Metabolite profiling of CHO cells with different growth characteristics

2012

Journal Article

Enhanced polyhydroxybutyrate production in transgenic sugarcane

Petrasovits, Lars A., Zhao, Lihan, McQualter, Richard B., Snell, Kristi D., Somleva, Maria N., Patterson, Nii A., Nielsen, Lars K. and Brumbley, Stevens M (2012). Enhanced polyhydroxybutyrate production in transgenic sugarcane. Plant Biotechnology Journal, 10 (5), 569-578. doi: 10.1111/j.1467-7652.2012.00686.x

Enhanced polyhydroxybutyrate production in transgenic sugarcane

2012

Journal Article

Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions

Nguyen, Quan, Palfreyman, Robin W., Chan, Leslie C. L., Reid, Steven and Nielsen, Lars K. (2012). Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions. PLoS One, 7 (5) e36324, e36324.1-e36324.15. doi: 10.1371/journal.pone.0036324

Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions

2012

Journal Article

Improving the robustness of a low-cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor-based statistical optimization routine

Huynh, Hoai T., Chan, Leslie C. L., Tran, Trinh T. B., Nielsen, Lars K. and Reid, Steven (2012). Improving the robustness of a low-cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor-based statistical optimization routine. Biotechnology Progress, 28 (3), 788-802. doi: 10.1002/btpr.1529

Improving the robustness of a low-cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor-based statistical optimization routine

2012

Journal Article

Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cells

Tran, Trinh T.B., Dietmair, Stefanie, Chan, Leslie C.L., Huynh, Hoai T., Nielsen, Lars K. and Reid, Steven (2012). Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cells. Methods, 56 (3), 396-407. doi: 10.1016/j.ymeth.2011.11.009

Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cells

2012

Journal Article

Mammalian cells as biopharmaceutical production hosts in the age of omics

Dietmair, Stefanie, Nielsen, Lars K. and Timmins, Nicholas E. (2012). Mammalian cells as biopharmaceutical production hosts in the age of omics. Biotechnology Journal, 7 (1), 75-89. doi: 10.1002/biot.201100369

Mammalian cells as biopharmaceutical production hosts in the age of omics

2012

Journal Article

Bioreactor for blood product production

Doran, Michael R., Aird, Ian Alexander, Marturana, Flavia, Timmins, Nicholas, Atkinson, Kerry and Nielsen, Lars K. (2012). Bioreactor for blood product production. Cell Transplantation, 21 (6), 1235-1244. doi: 10.3727/096368911X627363

Bioreactor for blood product production

2012

Conference Publication

Metabolomic Analysis of CHO Cultures with Different Growth Characteristics - Development of a Metabolite Extraction Protocol for Suspension Adapted Mammalian Cells

Dietmair, Stefanie, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Gray, Peter P., Kromer, Jens O. and Nielsen, Lars K. (2012). Metabolomic Analysis of CHO Cultures with Different Growth Characteristics - Development of a Metabolite Extraction Protocol for Suspension Adapted Mammalian Cells. 21st Annual Meeting of the European-Society-for-Animal-Cell-Technology (ESACT), Dublin Ireland, Jun 07-10, 2009. DORDRECHT: SPRINGER. doi: 10.1007/978-94-007-0884-6_6

Metabolomic Analysis of CHO Cultures with Different Growth Characteristics - Development of a Metabolite Extraction Protocol for Suspension Adapted Mammalian Cells

2012

Book Chapter

Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells

Dietmair, Stefanie, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Gray, Peter P., Krömer, Jens O. and Nielsen, Lars K. (2012). Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 37-41) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer.

Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells

2012

Book Chapter

Metabolic pathway engineering for hyaluronic acid production

Marcellin, Esteban, Chen, Wendy Y. and Nielsen, Lars K. (2012). Metabolic pathway engineering for hyaluronic acid production. Carbohydrate modifying biocatalysts. (pp. 571-584) edited by Peter Grundwald. Singapore: Pan Stanford Publishing. doi: 10.4032/9789814303484

Metabolic pathway engineering for hyaluronic acid production

2012

Conference Publication

Dynamic analysis of Saccharopolyspora erythraea life cycle in bioreactors; a systems approach

Licona Cassani, Cuauthemoc, Marcellin Saldana, Esteban Stefane and Nielsen, Lars K. (2012). Dynamic analysis of Saccharopolyspora erythraea life cycle in bioreactors; a systems approach. Actinobacteria within soil, Munster, Germany, 25-28 October 2012.

Dynamic analysis of Saccharopolyspora erythraea life cycle in bioreactors; a systems approach

2012

Conference Publication

Large Scale Ex Vivo Manufacture of Blood Cells

Timmins, Nicholas E. and Nielsen, Lars K. (2012). Large Scale Ex Vivo Manufacture of Blood Cells. 21st Annual Meeting of the European-Society-for-Animal-Cell-Technology (ESACT), Dublin Ireland, Jun 07-10, 2009. DORDRECHT: SPRINGER. doi: 10.1007/978-94-007-0884-6_92

Large Scale Ex Vivo Manufacture of Blood Cells

2012

Book Chapter

Large scale ex vivo manufacture of blood cells

Timmins, Nicholas E. and Nielsen, Lars K. (2012). Large scale ex vivo manufacture of blood cells. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 557-571) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer.

Large scale ex vivo manufacture of blood cells