Overview
Availability
- Dr Vikas Tillu is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Vikas Tillu’s works on UQ eSpace
2025
Journal Article
Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain
Gao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-en, Weeratunga, Saroja, Guo, Qian, Livingstone, Emma, Tham, Wai-Hong, Parton, Robert G. and Collins, Brett M. (2025). Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain. Journal of Cell Science, 138 (8). doi: 10.1242/jcs.263756
2025
Journal Article
Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
Chen, Kai-En, Tillu, Vikas A., Gopaldass, Navin, Chowdhury, Sudeshna Roy, Leneva, Natalya, Kovtun, Oleksiy, Ruan, Juanfang, Guo, Qian, Ariotti, Nicholas, Mayer, Andreas and Collins, Brett M. (2025). Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer. Nature Communications, 16 (1) 3568, 1. doi: 10.1038/s41467-025-58846-8
2024
Journal Article
Precision in situ cryo-correlative light and electron microscopy of optogenetically-positioned organelles
Tillu, Vikas A., Redpath, Gregory M. I., Rae, James, Ruan, Juanfang, Yao, Yin, Cagigas, Maria L., Whan, Renee, Hardeman, Edna C., Gunning, Peter W., Ananthanarayanan, Vaishnavi, Parton, Robert G. and Ariotti, Nicholas A. (2024). Precision in situ cryo-correlative light and electron microscopy of optogenetically-positioned organelles. Journal of Cell Science, 137 (20) jcs262163, 1-16. doi: 10.1242/jcs.262163
2024
Journal Article
First person-Vikas Tillu
Tillu, Vikas (2024). First person-Vikas Tillu. Journal of Cell Science, 137 (20) jcs263557, 1-2. doi: 10.1242/jcs.263557
2023
Journal Article
Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience
Brooks, John W., Tillu, Vikas, Eckert, Julia, Verma, Suzie, Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2023). Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience. Molecular Biology of the Cell, 34 (12) ar120, 1-14. doi: 10.1091/mbc.e23-05-0163
2023
Conference Publication
Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles
Gao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-En, Weeratunga, Saroja, Guo, Qian, Parton, Robert G. and Collins, Brett M. (2023). Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086825
2023
Conference Publication
Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles
Gao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-en, Weeratunga, Saroja, Guo, Qian, Parton, Robert G. and Collins, Brett M. (2023). Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell.
2022
Journal Article
Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins
Healy, Michael D., Sacharz, Joanna, McNally, Kerrie E., McConville, Calum, Tillu, Vikas A., Hall, Ryan J., Chilton, Molly, Cullen, Peter J., Mobli, Mehdi, Ghai, Rajesh, Stroud, David A. and Collins, Brett M. (2022). Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins. Structure, 30 (12), 1590-1602.e6. doi: 10.1016/j.str.2022.10.001
2022
Journal Article
Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins
Paul, Blessy, Weeratunga, Saroja, Tillu, Vikas A., Hariri, Hanaa, Henne, W. Mike and Collins, Brett M. (2022). Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins. Frontiers in Cell and Developmental Biology, 10 826688, 826688. doi: 10.3389/fcell.2022.826688
2021
Journal Article
Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle
Lo, Harriet P., Lim, Ye-Wheen, Xiong, Zherui, Martel, Nick, Ferguson, Charles, Ariotti, Nicholas, Giacomotto, Jean, Rae, James, Floetenmeyer, Matthias, Moradi, Shayli Varasteh, Gao, Ya, Tillu, Vikas A., Xia, Di, Wang, Huang, Rahnama, Samira, Nixon, Susan J., Bastiani, Michele, Day, Ryan D., Smith, Kelly A., Palpant, Nathan J., Johnston, Wayne A., Alexandrov, Kirill, Collins, Brett M., Hall, Thomas E. and Parton, Robert G. (2021). Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. Journal of Cell Biology, 220 (12) e201905065. doi: 10.1083/jcb.201905065
2021
Journal Article
Key phases in the formation of caveolae
Parton, Robert G., Tillu, Vikas, McMahon, Kerrie-Ann and Collins, Brett M. (2021). Key phases in the formation of caveolae. Current Opinion in Cell Biology, 71, 7-14. doi: 10.1016/j.ceb.2021.01.009
2021
Journal Article
Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
McMahon, Kerrie-Ann, Stroud, David A., Gambin, Yann, Tillu, Vikas, Bastiani, Michele, Sierecki, Emma, Polinkovsky, Mark E., Hall, Thomas E., Gomez, Guillermo A., Wu, Yeping, Parat, Marie-Odile, Martel, Nick, Lo, Harriet P., Khanna, Kum Kum, Alexandrov, Kirill, Daly, Roger, Yap, Alpha, Ryan, Michael T. and Parton, Robert G. (2021). Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response. eLife, 10 e61407, 1-35. doi: 10.7554/elife.61407
2021
Journal Article
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
Tillu, Vikas A., Rae, James, Gao, Ya, Ariotti, Nicholas, Floetenmeyer, Matthias, Kovtun, Oleksiy, McMahon, Kerrie-Ann, Chaudhary, Natasha, Parton, Robert G. and Collins, Brett M. (2021). Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation. Nature Communications, 12 (1) 931, 931. doi: 10.1038/s41467-021-21035-4
2021
Journal Article
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae
Zhou, Yong, Ariotti, Nicholas, Rae, James, Liang, Hong, Tillu, Vikas, Tee, Shern, Bastiani, Michele, Bademosi, Adekunle T., Collins, Brett M., Meunier, Frederic A., Hancock, John F. and Parton, Robert G. (2021). Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae. Journal of Cell Biology, 220 (3) e202005138. doi: 10.1083/jcb.202005138
2020
Journal Article
Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8), 2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007
2019
Journal Article
Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
McMahon, Kerrie-Ann, Wu, Yeping, Gambin, Yann, Sierecki, Emma, Tillu, Vikas A., Hall, Thomas, Martel, Nick, Okano, Satomi, Moradi, Shayli Varasteh, Ruelcke, Jayde E., Ferguson, Charles, Yap, Alpha S., Alexandrov, Kirill, Hill, Michelle M. and Parton, Robert G. (2019). Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nature Communications, 10 (1) 3279, 3279. doi: 10.1038/s41467-019-11111-1
2018
Journal Article
Molecular basis for membrane recruitment by the PX and C2 domains of Class II Phosphoinositide 3-Kinase-C2α
Chen, Kai-En, Tillu, Vikas A., Chandra, Mintu and Collins, Brett M. (2018). Molecular basis for membrane recruitment by the PX and C2 domains of Class II Phosphoinositide 3-Kinase-C2α. Structure, 26 (12), 1612-1625.e4. doi: 10.1016/j.str.2018.08.010
2018
Journal Article
A variable undecad repeat domain in cavin1 regulates caveola formation and stability
Tillu, Vikas A., Lim, Ye-Wheen, Kovtun, Oleksiy, Mureev, Sergey, Ferguson, Charles, Bastiani, Michele, McMahon, Kerrie-Ann, Lo, Harriet P., Hall, Thomas E., Alexandrov, Kirill, Collins, Brett M. and Parton, Robert G. (2018). A variable undecad repeat domain in cavin1 regulates caveola formation and stability. EMBO Reports, 19 (9) e45775. doi: 10.15252/embr.201845775
2018
Journal Article
Structural insights into the architecture and membrane interactions of the conserved COMMD proteins
Healy, Michael D., Hospenthal, Manuela K., Hall, Ryan J., Chandra, Mintu, Chilton, Molly, Tillu, Vikas, Chen, Kai-En, Celligoi, Dion J., McDonald, Fiona J., Cullen, Peter J., Lott, J. Shaun, Collins, Brett M. and Ghai, Rajesh (2018). Structural insights into the architecture and membrane interactions of the conserved COMMD proteins. eLife, 7 e35898. doi: 10.7554/elife.35898
2018
Journal Article
Caveolae
Parton, Robert G, Tillu, Vikas A and Collins, Brett M (2018). Caveolae. Current Biology, 28 (8), R402-R405. doi: 10.1016/j.cub.2017.11.075
Supervision
Availability
- Dr Vikas Tillu is:
- Available for supervision
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