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2024 Journal Article Pyritic stromatolites from the Paleoarchean Dresser Formation, Pilbara Craton: resolving biogenicity and hydrothermally influenced ecosystem dynamicsBaumgartner, Raphael J., Van Kranendonk, Martin J., Caruso, Stefano, Campbell, Kathleen A., Dobson, Michaela J., Teece, Bronwyn L., Verrall, Michael, Homann, Martin, Lalonde, Stefan and Visscher, Pieter T. (2024). Pyritic stromatolites from the Paleoarchean Dresser Formation, Pilbara Craton: resolving biogenicity and hydrothermally influenced ecosystem dynamics. Geobiology, 22 (4) e12610, 1-26. doi: 10.1111/gbi.12610 |
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2024 Journal Article Genetic influence on within-person longitudinal change in anthropometric traits in the UK BiobankKemper, Kathryn E., Sidorenko, Julia, Wang, Huanwei, Hayes, Ben J., Wray, Naomi R., Yengo, Loic, Keller, Matthew C., Goddard, Michael and Visscher, Peter M. (2024). Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank. Nature Communications, 15 (1) 3776, 3776. doi: 10.1038/s41467-024-47802-7 |
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2024 Journal Article Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traitsKeaton, Jacob M., Kamali, Zoha, Xie, Tian, Vaez, Ahmad, Williams, Ariel, Goleva, Slavina B., Ani, Alireza, Evangelou, Evangelos, Hellwege, Jacklyn N., Yengo, Loic, Young, William J., Traylor, Matthew, Giri, Ayush, Zheng, Zhili, Zeng, Jian, Chasman, Daniel I., Morris, Andrew P., Caulfield, Mark J., Hwang, Shih-Jen, Kooner, Jaspal S., Conen, David, Attia, John R., Morrison, Alanna C., Loos, Ruth J. F., Kristiansson, Kati, Schmidt, Reinhold, Hicks, Andrew A., Pramstaller, Peter P., Nelson, Christopher P. ... ICBP Consortium (2024). Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nature Genetics, 56 (5), 1-14. doi: 10.1038/s41588-024-01714-w |
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2024 Journal Article Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestriesZheng, Zhili, Liu, Shouye, Sidorenko, Julia, Wang, Ying, Lin, Tian, Yengo, Loic, Turley, Patrick, Ani, Alireza, Wang, Rujia, Nolte, Ilja M., Snieder, Harold, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A., Lopera Maya, Esteban A., Sanna, Serena, Swertz, Morris A., Vonk, Judith M., Wijmenga, Cisca, Yang, Jian, Wray, Naomi R., Goddard, Michael E., Visscher, Peter M., Zeng, Jian and LifeLines Cohort Study (2024). Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. Nature Genetics, 56 (5), 1-11. doi: 10.1038/s41588-024-01704-y |
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2024 Journal Article Genome-wide studies reveal genetic risk factors for hepatic fat contentLi, Yanni, Van Den Berg, Eline H., Kurilshikov, Alexander, Zhernakova, Dasha V., Lifelines Cohort Study, Gacesa, Ranko, Hu, Shixian, Lopera-Maya, Esteban A., Zhernakova, Alexandra, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A., Lopera-Maya, Esteban A., Nolte, Ilja M., Sanna, Serena, Snieder, Harold, Swertz, Morris A., Visscher, Peter M. (Lifelines Cohort Study group member), Vonk, Judith M., Wijmenga, Cisca, De Meijer, Vincent E., Sanna, Serena, Dullaart, Robin P. F., Blokzijl, Hans, Festen, Eleonora A. M., Fu, Jingyuan and Weersma, Rinse K. (2024). Genome-wide studies reveal genetic risk factors for hepatic fat content. Genomics, Proteomics and Bioinformatics, 22 (2) qzae031, 1-12. doi: 10.1093/gpbjnl/qzae031 |
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2024 Journal Article Genetic control of DNA methylation is largely shared across European and East Asian populationsHatton, Alesha A., Cheng, Fei-Fei, Lin, Tian, Shen, Ren-Juan, Chen, Jie, Zheng, Zhili, Qu, Jia, Lyu, Fan, Harris, Sarah E., Cox, Simon R., Jin, Zi-Bing, Martin, Nicholas G., Fan, Dongsheng, Montgomery, Grant W., Yang, Jian, Wray, Naomi R., Marioni, Riccardo E., Visscher, Peter M. and McRae, Allan F. (2024). Genetic control of DNA methylation is largely shared across European and East Asian populations. Nature Communications, 15 (1) 2713, 1-12. doi: 10.1038/s41467-024-47005-0 |
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2024 Journal Article Unravelling the complex causal effects of substance use behaviours on common diseasesXue, Angli, Zhu, Zhihong, Wang, Huanwei, Jiang, Longda, Visscher, Peter M., Zeng, Jian and Yang, Jian (2024). Unravelling the complex causal effects of substance use behaviours on common diseases. Communications Medicine, 4 (1) 43, 1-13. doi: 10.1038/s43856-024-00473-3 |
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2024 Journal Article Host genetic regulation of human gut microbial structural variationZhernakova, Daria V., Wang, Daoming, Liu, Lei, Andreu-Sánchez, Sergio, Zhang, Yue, Ruiz-Moreno, Angel J., Peng, Haoran, Plomp, Niels, Del Castillo-Izquierdo, Ángela, Gacesa, Ranko, Lopera-Maya, Esteban A., Temba, Godfrey S., Kullaya, Vesla I., van Leeuwen, Sander S., Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A., Nolte, Ilja M., Sanna, Serena, Snieder, Harold, Swertz, Morris A., Visscher, Peter M., Vonk, Judith M., Xavier, Ramnik J., de Mast, Quirijn, Joosten, Leo A. B., Riksen, Niels P., Rutten, Joost H. W. ... Fu, Jingyuan (2024). Host genetic regulation of human gut microbial structural variation. Nature, 625 (7996), 813-821. doi: 10.1038/s41586-023-06893-w |
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2024 Journal Article Erratum: autism-related dietary preferences mediate autism-gut microbiome associationsYap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2024). Erratum: autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 187 (2), 495-510. doi: 10.1016/j.cell.2023.12.001 |
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2023 Journal Article OTTERS: a powerful TWAS framework leveraging summary-level reference dataDai, Qile, Zhou, Geyu, Zhao, Hongyu, Võsa, Urmo, Franke, Lude, Battle, Alexis, Teumer, Alexander, Lehtimäki, Terho, Raitakari, Olli T., Esko, Tõnu, Agbessi, Mawussé, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand Kumar, Arindrarto, Wibowo, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Jan Bonder, Marc, Boomsma, Dorret I., Christiansen, Mark W., Claringbould, Annique, Deelen, Patrick, Favé, Marie-Julie, Frayling, Timothy, Gharib, Sina A., Gibson, Greg, Heijmans, Bastiaan T., Hemani, Gibran ... Yang, Jingjing (2023). OTTERS: a powerful TWAS framework leveraging summary-level reference data. Nature Communications, 14 (1) 1271, 1-13. doi: 10.1038/s41467-023-36862-w |
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2023 Journal Article Cross-ancestry analyses identify new genetic loci associated with 25-hydroxyvitamin DWang, Xiaotong, Hivert, Valentin, Groot, Shiane, Wang, Ying, Yengo, Loic, McGrath, John J., Kemper, Kathryn E., Visscher, Peter M., Wray, Naomi R. and Revez, Joana A. (2023). Cross-ancestry analyses identify new genetic loci associated with 25-hydroxyvitamin D. PLoS Genetics, 19 (11) e1011033, 1-24. doi: 10.1371/journal.pgen.1011033 |
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2023 Conference Publication Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestriesZeng, Jian, Zheng, Zhili, Liu, Shouye, Sidorenko, Julia, Yengo, Loic, Turley, Patrick, Ani, Alireza, Wang, Rujia, Nolte, Ilja, Snieder, Harold, Yang, Jian, Wray, Naomi, Goddard, Michael and Visscher, Peter (2023). Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. World Congress of Psychiatric Genetics (WCPG), Montreal, ON, Canada, 10 - 14 October 2023. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2023.08.063 |
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2023 Journal Article Community-wide genome sequencing reveals 30 years of Darwin’s finch evolutionEnbody, Erik D., Sendell-Price, Ashley T., Sprehn, C. Grace, Rubin, Carl-Johan, Visscher, Peter M., Grant, B. Rosemary, Grant, Peter R. and Andersson, Leif (2023). Community-wide genome sequencing reveals 30 years of Darwin’s finch evolution. Science, 381 (6665) eadf6218, 1-10. doi: 10.1126/science.adf6218 |
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2023 Journal Article Boosting the power of genome-wide association studies within and across ancestries by using polygenic scoresCampos, Adrian I., Namba, Shinichi, Lin, Shu-Chin, Nam, Kisung, Sidorenko, Julia, Wang, Huanwei, Kamatani, Yoichiro, The Biobank Japan Project, Wang, Ling-Hua, Lee, Seunggeun, Lin, Yen-Feng, Feng, Yen-Chen Anne, Okada, Yukinori, Visscher, Peter M. and Yengo, Loic (2023). Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores. Nature Genetics, 55 (10), 1769-1776. doi: 10.1038/s41588-023-01500-0 |
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2023 Journal Article Chromosomal inversion polymorphisms shape human brain morphologyWang, Hao, Makowski, Carolina, Zhang, Yanxiao, Qi, Anna, Kaufmann, Tobias, Smeland, Olav B., Fiecas, Mark, Yang, Jian, Visscher, Peter M. and Chen, Chi-Hua (2023). Chromosomal inversion polymorphisms shape human brain morphology. Cell Reports, 42 (8) 112896, 112896. doi: 10.1016/j.celrep.2023.112896 |
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2023 Journal Article Joint analysis of GWAS and multi-omics QTL summary statistics reveals a large fraction of GWAS signals shared with molecular phenotypesWu, Yang, Qi, Ting, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2023). Joint analysis of GWAS and multi-omics QTL summary statistics reveals a large fraction of GWAS signals shared with molecular phenotypes. Cell Genomics, 3 (8) 100344, 100344. doi: 10.1016/j.xgen.2023.100344 |
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2023 Journal Article Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptionsMaury, Eduardo A., Sherman, Maxwell A., Genovese, Giulio, Gilgenast, Thomas G., Kamath, Tushar, Burris, S. J., Rajarajan, Prashanth, Flaherty, Erin, Akbarian, Schahram, Chess, Andrew, McCarroll, Steven A., Loh, Po-Ru, Phillips-Cremins, Jennifer E., Brennand, Kristen J., Macosko, Evan Z., Walters, James T.R., O'Donovan, Michael, Sullivan, Patrick, Marshall, Christian R., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wang, Zhouzhi, Scherer, Stephen W., Howrigan, Daniel P, Ripke, Stephan, Bulik-Sullivan, Brendan, Farh, Kai-How, Fromer, Menachem, Goldstein, Jacqueline I. ... Walsh, Christopher A. (2023). Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Cell Genomics, 3 (8) 100356, 1-21. doi: 10.1016/j.xgen.2023.100356 |
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2023 Journal Article Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritabilityWang, Xiaotong, Walker, Alicia, Revez, Joana A., Ni, Guiyan, Visscher, Peter M., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan R.I., Colodro-Conde, Lucía ... Sullivan, Patrick F. (2023). Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability. The American Journal of Human Genetics, 110 (7), 1207-1215. doi: 10.1016/j.ajhg.2023.06.006 |
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2023 Journal Article Rare genetic variants underlie outlying levels of DNA methylation and gene-expressionChundru, V. Kartik, Marioni, Riccardo E., Pendergast, James G. D., Lin, Tian, Beveridge, Allan J., Martin, Nicholas G, Montgomery, Grant W., Hume, David A., Deary, Ian J., Visscher, Peter M., Wray, Naomi R. and McRae, Allan F. (2023). Rare genetic variants underlie outlying levels of DNA methylation and gene-expression. Human Molecular Genetics, 32 (11), 1912-1921. doi: 10.1093/hmg/ddad028 |
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2023 Journal Article Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophreniaHsu, Yu-Han H., Pintacuda, Greta, Liu, Ruize, Nacu, Eugeniu, Kim, April, Tsafou, Kalliopi, Petrossian, Natalie, Crotty, William, Suh, Jung Min, Riseman, Jackson, Martin, Jacqueline M., Biagini, Julia C., Mena, Daya, Ching, Joshua K.T., Malolepsza, Edyta, Li, Taibo, Singh, Tarjinder, Ge, Tian, Egri, Shawn B., Tanenbaum, Benjamin, Stanclift, Caroline R., Apffel, Annie M., Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil ... Lage, Kasper (2023). Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience, 26 (5) 106701, 1-28. doi: 10.1016/j.isci.2023.106701 |
