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2025 Journal Article Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipidsBentley, Amy R., Brown, Michael R., Musani, Solomon K., Schwander, Karen L., Winkler, Thomas W., Sims, Mario, Kilpeläinen, Tuomas O., Aschard, Hugues, Bartz, Traci M., Bielak, Lawrence F., Chai, Jin-Fang, Chitrala, Kumaraswamy Naidu, Franceschini, Nora, Graff, Mariaelisa, Guo, Xiuqing, Hartwig, Fernando P., Horimoto, Andrea R.V.R., Lim, Elise, Liu, Yongmei, Manning, Alisa K., Nolte, Ilja M., Noordam, Raymond, Richard, Melissa A., Smith, Albert V., Sung, Yun Ju, Vojinovic, Dina, Wang, Rujia, Wang, Yujie, Feitosa, Mary F. ... Fox, Ervin R. (2025). Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids. Translational Psychiatry, 15 (1) 207, 1. doi: 10.1038/s41398-025-03418-z |
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2025 Journal Article MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causalityvan der Graaf, Adriaan, Warmerdam, Robert, Auwerx, Chiara, Xie, Manke, Wood, Andrew R., Westra, Harm-Jan, Weiss, Stefan, Völker, Uwe, Visscher, Peter M., Viñuela, Ana, Verlouw, Joost, Veldink, Jan, Tokolyi, Alex, Teumer, Alexander, Souto, Juan Carlos, Soria, José Manuel, Slagboom, Eline, Singleton, Andrew, Raitoharju, Emma, Raitakari, Olli T., Prokisch, Holger, Peters, Annette, Persyn, Elodie, Paul, Dirk S., Pasaniuc, Bogdan, Ophoff, Roel, Nauck, Matthias, Nagpal, Sini, Montgomery, Grant W. ... eQTLGen Consortium (2025). MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality. Nature Communications, 16 (1) 6112, 1-19. doi: 10.1038/s41467-025-60868-1 |
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2025 Journal Article Harnessing functional annotation to improve the accuracy and transferability of polygenic scoresZeng, Jian and Visscher, Peter M. (2025). Harnessing functional annotation to improve the accuracy and transferability of polygenic scores. Nature Reviews Genetics. doi: 10.1038/s41576-025-00893-4 |
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2025 Journal Article Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smokingHe, Weixiong, van der Most, Peter J., Ong, Jue-Sheng, Hwang, Liang-Dar, Wu, Yeda, Magnø, Morten S., Vehof, Jelle, Krebs, Kristi, Mauring, Laura, Õunap, Katrin, Abner, Erik, Martin, Nicholas G., Plotnikov, Denis, Jiang, Chen, Melles, Ronald B., Gharahkhani, Puya, Snieder, Harold, Palumaa, Teele, Kaljurand, Kuldar, Guggenheim, Jeremy A., Mackey, David A., Engle, Elizabeth C., Choquet, Hélène, MacGregor, Stuart, Lifelines Cohort Study, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A. ... Wray, Naomi (2025). Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking. Nature Communications, 16 (1) 7890, 1-14. doi: 10.1038/s41467-025-62456-9 |
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2025 Journal Article The contribution of gametic phase disequilibrium to the heritability of complex traitsZhang, Yuanxiang, Sakaue, Saori, Morris, Sam, Graff, Mariaelisa, Yamamoto, Kenichi, Chen, Zhengming, Li, Liming, Keller, Matthew C., Goddard, Michael E., Walters, Robin G., Okada, Yukinori, Visscher, Peter M. and Yengo, Loic (2025). The contribution of gametic phase disequilibrium to the heritability of complex traits. Nature Genetics, 57 (6) e1006495, 1418-1425. doi: 10.1038/s41588-025-02192-4 |
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2025 Journal Article Socio-economic status is a social construct with heritable components and genetic consequencesAbdellaoui, Abdel, Martin, Hilary C., Kolk, Martin, Rutherford, Adam, Muthukrishna, Michael, Tropf, Felix C., Mills, Melinda C., Zietsch, Brendan P., Verweij, Karin J. H. and Visscher, Peter M. (2025). Socio-economic status is a social construct with heritable components and genetic consequences. Nature Human Behaviour, 9 (5) e12925, 1-13. doi: 10.1038/s41562-025-02150-4 |
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2025 Journal Article Author Correction: Heritable polygenic editing: the next frontier in genomic medicine?Visscher, Peter M., Gyngell, Christopher, Yengo, Loic and Savulescu, Julian (2025). Author Correction: Heritable polygenic editing: the next frontier in genomic medicine?. Nature, 640 (8058), E5-E5. doi: 10.1038/s41586-025-08904-4 |
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2025 Journal Article Heritable polygenic editing: the next frontier in genomic medicine?Visscher, Peter M., Gyngell, Christopher, Yengo, Loic and Savulescu, Julian (2025). Heritable polygenic editing: the next frontier in genomic medicine?. Nature, 637 (8046) 86, 637-645. doi: 10.1038/s41586-024-08300-4 |
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2025 Journal Article Grey‐matter structure markers of Alzheimer's disease, Alzheimer's conversion, functioning and cognition: a meta‐analysis across 11 CohortsCouvy‐Duchesne, Baptiste, Frouin, Vincent, Bouteloup, Vincent, Koussis, Nikitas, Sidorenko, Julia, Jiang, Jiyang, Wink, Alle Meije, Lorenzini, Luigi, Barkhof, Frederik, Trollor, Julian N., Mangin, Jean‐François, Sachdev, Perminder S., Brodaty, Henry, Lupton, Michelle K., Breakspear, Michael, Colliot, Olivier, Visscher, Peter M., Wray, Naomi R., for the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarkers and Lifestyle flagship study of ageing, the Alzheimer's Disease Repository Without Borders Investigators and the MEMENTO cohort Study Group (2025). Grey‐matter structure markers of Alzheimer's disease, Alzheimer's conversion, functioning and cognition: a meta‐analysis across 11 Cohorts. Human Brain Mapping, 46 (2) e70089, 1-21. doi: 10.1002/hbm.70089 |
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2024 Journal Article Distinct genetic liability profiles define clinically relevant patient strata across common diseasesTrastulla, Lucia, Dolgalev, Georgii, Moser, Sylvain, Jiménez-Barrón, Laura T., Andlauer, Till F. M., von Scheidt, Moritz, Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Stahl, Eli A., Domenici, Enrico, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W., Blackwood, Douglas H. R., Borglum, Anders D., Bramon, Elvira, Bruggeman, Richard ... Ziller, Michael J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications, 15 (1) 5534, 1-28. doi: 10.1038/s41467-024-49338-2 |
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2024 Journal Article Radiogenomics Pilot Study: Association Between Radiomics and Single Nucleotide Polymorphism-Based Microarray Copy Number Variation in Diagnosing Renal Oncocytoma and Chromophobe Renal Cell CarcinomaAlhussaini, Abeer J., Veluchamy, Abirami, Jawli, Adel, Kernohan, Neil, Tang, Benjie, Palmer, Colin N. A., Steele, J. Douglas and Nabi, Ghulam (2024). Radiogenomics Pilot Study: Association Between Radiomics and Single Nucleotide Polymorphism-Based Microarray Copy Number Variation in Diagnosing Renal Oncocytoma and Chromophobe Renal Cell Carcinoma. International Journal of Molecular Sciences, 25 (23) 12512, 12512. doi: 10.3390/ijms252312512 |
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2024 Journal Article Development and external validation of multivariable risk models to predict incident and resolved neuropathic pain: a DOLORisk Dundee study (vol 270, pg 1076, 2022)Hebert, Harry L., Veluchamy, Abirami, Baskozos, Georgios, Fardo, Francesca, Van Ryckeghem, Dimitri, Pearson, Ewan R., Colvin, Lesley A., Crombez, Geert, Bennett, David L. H., Meng, Weihua, Palmer, Colin N. A. and Smith, Blair H. (2024). Development and external validation of multivariable risk models to predict incident and resolved neuropathic pain: a DOLORisk Dundee study (vol 270, pg 1076, 2022). Journal of Neurology, 271 (12), 7652-7653. doi: 10.1007/s00415-024-12721-6 |
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2024 Journal Article The importance of family-based sampling for biobanksDavies, Neil M., Hemani, Gibran, Neiderhiser, Jenae M., Martin, Hilary C., Mills, Melinda C., Visscher, Peter M., Yengo, Loïc, Young, Alexander Strudwick and Keller, Matthew C. (2024). The importance of family-based sampling for biobanks. Nature, 634 (8035), 795-803. doi: 10.1038/s41586-024-07721-5 |
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2024 Journal Article Genetic architecture reconciles linkage and association studies of complex traitsSidorenko, Julia, Couvy-Duchesne, Baptiste, Kemper, Kathryn E., Moen, Gunn-Helen, Bhatta, Laxmi, Åsvold, Bjørn Olav, Mägi, Reedik, Estonian Biobank Research Team, Ani, Alireza, Wang, Rujia, Nolte, Ilja M., Lifelines Cohort Study, Nolte, Ilja M., Gordon, Scott, Hayward, Caroline, Campbell, Archie, Benjamin, Daniel J., Cesarini, David, Evans, David M., Goddard, Michael E., Haley, Chris S., Porteous, David, Medland, Sarah E., Martin, Nicholas G., Snieder, Harold, Metspalu, Andres, Hveem, Kristian, Brumpton, Ben, Visscher, Peter M. and Yengo, Loic (2024). Genetic architecture reconciles linkage and association studies of complex traits. Nature Genetics, 56 (11), 2352-2360. doi: 10.1038/s41588-024-01940-2 |
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2024 Journal Article Carbonate mud production in lakes is driven by degradation of microbial substancesBoussagol, P., Vennin, E., Monna, F., Millet, L., Bonnotte, A., Motreuil, S., Bundeleva, I., Rius, D. and Visscher, P. T. (2024). Carbonate mud production in lakes is driven by degradation of microbial substances. Communications Earth & Environment, 5 (1) 533. doi: 10.1038/s43247-024-01709-9 |
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2024 Journal Article The eukaryome of modern microbialites reveals distinct colonization across aquatic ecosystemsBonacolta, Anthony M., Visscher, Pieter T., del Campo, Javier and White III, Richard Allen (2024). The eukaryome of modern microbialites reveals distinct colonization across aquatic ecosystems. npj Biofilms and Microbiomes, 10 (1) 78, 1-11. doi: 10.1038/s41522-024-00547-z |
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2024 Journal Article Pyritic stromatolites from the Paleoarchean Dresser Formation, Pilbara Craton: resolving biogenicity and hydrothermally influenced ecosystem dynamicsBaumgartner, Raphael J., Van Kranendonk, Martin J., Caruso, Stefano, Campbell, Kathleen A., Dobson, Michaela J., Teece, Bronwyn L., Verrall, Michael, Homann, Martin, Lalonde, Stefan and Visscher, Pieter T. (2024). Pyritic stromatolites from the Paleoarchean Dresser Formation, Pilbara Craton: resolving biogenicity and hydrothermally influenced ecosystem dynamics. Geobiology, 22 (4) e12610, 1-26. doi: 10.1111/gbi.12610 |
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2024 Journal Article Genetic influence on within-person longitudinal change in anthropometric traits in the UK BiobankKemper, Kathryn E., Sidorenko, Julia, Wang, Huanwei, Hayes, Ben J., Wray, Naomi R., Yengo, Loic, Keller, Matthew C., Goddard, Michael and Visscher, Peter M. (2024). Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank. Nature Communications, 15 (1) 3776, 3776. doi: 10.1038/s41467-024-47802-7 |
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2024 Journal Article Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestriesZheng, Zhili, Liu, Shouye, Sidorenko, Julia, Wang, Ying, Lin, Tian, Yengo, Loic, Turley, Patrick, Ani, Alireza, Wang, Rujia, Nolte, Ilja M., Snieder, Harold, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A., Lopera Maya, Esteban A., Sanna, Serena, Swertz, Morris A., Vonk, Judith M., Wijmenga, Cisca, Yang, Jian, Wray, Naomi R., Goddard, Michael E., Visscher, Peter M., Zeng, Jian and LifeLines Cohort Study (2024). Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. Nature Genetics, 56 (5), 1-11. doi: 10.1038/s41588-024-01704-y |
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2024 Journal Article Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traitsKeaton, Jacob M., Kamali, Zoha, Xie, Tian, Vaez, Ahmad, Williams, Ariel, Goleva, Slavina B., Ani, Alireza, Evangelou, Evangelos, Hellwege, Jacklyn N., Yengo, Loic, Young, William J., Traylor, Matthew, Giri, Ayush, Zheng, Zhili, Zeng, Jian, Chasman, Daniel I., Morris, Andrew P., Caulfield, Mark J., Hwang, Shih-Jen, Kooner, Jaspal S., Conen, David, Attia, John R., Morrison, Alanna C., Loos, Ruth J. F., Kristiansson, Kati, Schmidt, Reinhold, Hicks, Andrew A., Pramstaller, Peter P., Nelson, Christopher P. ... ICBP Consortium (2024). Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nature Genetics, 56 (5), 1-14. doi: 10.1038/s41588-024-01714-w |
