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2024 Journal Article Antibiotic dose optimisation in the critically ill: targets, evidence and future strategiesDyer, Christopher J., De Waele, Jan J. and Roberts, Jason A. (2024). Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies. Current Opinion in Critical Care, 30 (5), 439-447. doi: 10.1097/MCC.0000000000001187 |
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2024 Journal Article Effect of two hydration strategies on CapillarySodium concentrations in runners participating in 170-km trail race: The 2015 UltraTrail du Mont-Blanc experienceCoulomb, Rémy, Basset, Patrick, Mezzarobba, Myriam, Masseguin, Christophe, Lefrant, Jean-Yves, Mura, Thibault, Roberts, Jason A. and Mares, Olivier (2024). Effect of two hydration strategies on CapillarySodium concentrations in runners participating in 170-km trail race: The 2015 UltraTrail du Mont-Blanc experience. Clinical Journal of Sport Medicine, 35 (5), 549-553. doi: 10.1097/JSM.0000000000001266 |
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2023 Journal Article Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO studyNovy, Emmanuel, Abdul-Aziz, Mohd H., Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Levkovich, Bianca J., McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Parker, Suzanne, Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2023). Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 68 (1) e0120123, e0120123. doi: 10.1128/aac.01201-23 |
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2023 Journal Article A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjectsHernández-Mitre, María Patricia, Wallis, Steven C., Morgan, Elizabeth E., Dudley, Michael N., Loutit, Jeffery S., Griffith, David C. and Roberts, Jason A. (2023). A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects. Antimicrobial Agents and Chemotherapy, 68 (1) e0109923, 1-12. doi: 10.1128/aac.01099-23 |
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2023 Journal Article AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?Goutelle, Sylvain, Wallet, Florent, Thoma, Yann, Peclard, Jean-Rémi, Bourguignon, Laurent, Cohen, Sabine, Kipnis, Eric, Roberts, Jason, Allaouchiche, Bernard and Friggeri, Arnaud (2023). AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?. Anaesthesia Critical Care and Pain Medicine, 42 (6) 101286, 1-4. doi: 10.1016/j.accpm.2023.101286 |
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2023 Journal Article Comment: Is off-label medication use in the ICU a problem?Cotta, Menino O., Roberts, Jason A. and Reade, Michael C. (2023). Comment: Is off-label medication use in the ICU a problem?. Critical Care, 27 (1) 288, 288. doi: 10.1186/s13054-023-04546-y |
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2023 Journal Article Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteriaFresán, Daniel, Luque, Sonia, Benítez-Cano, Adela, Sorlí, Luisa, Montero, María Milagro, De-Antonio, Marta, Vega, Victoria, Roberts, Jason A., Horcajada, Juan P. and Grau, Santiago (2023). Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteria. Journal of Antimicrobial Chemotherapy, 78 (12), 2810-2815. doi: 10.1093/jac/dkad296 |
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2023 Journal Article Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort studyChai, Ming G., Roberts, Jason A., Kelly, Christina F., Ungerer, Jacobus P.J., McWhinney, Brett C., Lipman, Jeffrey, Farkas, Andras and Cotta, Menino O. (2023). Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study. Anaesthesia Critical Care and Pain Medicine, 42 (6) 101296, 101296. doi: 10.1016/j.accpm.2023.101296 |
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2023 Journal Article Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that’ s the questionHo, Kwok M., Lee, Anna, Wu, William, Chan, Matthew T. V., Ling, Lowell, Lipman, Jeffrey, Roberts, Jason, Litton, Edward, Joynt, Gavin M. and Wong, Martin (2023). Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that’ s the question. Journal of Geriatric Cardiology, 20 (11), 813-823. doi: 10.26599/1671-5411.2023.11.004 |
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2023 Journal Article Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasisNovy, Emmanuel, Roger, Claire, Roberts, Jason A. and Cotta, Menino Osbert (2023). Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis. Critical Care, 27 (1) 449, 1-17. doi: 10.1186/s13054-023-04742-w |
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2023 Journal Article Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohortCucci, Michaelia D., Gerlach, Anthony T., Mangira, Caroline, Murphy, Claire V., Roberts, Jason A., Udy, Andrew A., Dowling, Thomas C. and Mullen, Chanda L. (2023). Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohort. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (11), 1131-1138. doi: 10.1002/phar.2743 |
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2023 Journal Article In silico evaluation of a beta‐lactam dosing guideline among adults with serious infectionsWilliams, Paul, Cotta, Menino Osbert, Abdul‐Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A. (2023). In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (11), 1121-1130. doi: 10.1002/phar.2753 |
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2023 Journal Article Early oral antibiotic switch in Staphylococcus aureus bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocolde Kretser, Dana, Mora, Jocelyn, Bloomfield, Max, Campbell, Anita, Cheng, Matthew P., Guy, Stephen, Hensgens, Marjolein, Kalimuddin, Shirin, Lee, Todd C., Legg, Amy, Mahar, Robert K., Marks, Michael, Marsh, Julie, Mcglothin, Anna, Morpeth, Susan C., Sud, Archana, Ten Oever, Jaap, Yahav, Dafna, Bonten, Marc, Bowen, Asha C., Daneman, Nick, van Hal, Sebastiaan J., Heriot, George S., Lewis, Roger J., Lye, David C., Mcquilten, Zoe, Paterson, David L., Owen Robinson, J., Roberts, Jason A. ... Goodman, Anna L. (2023). Early oral antibiotic switch in Staphylococcus aureus bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol. Clinical Infectious Diseases, 79 (4), 871-887. doi: 10.1093/cid/ciad666 |
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2023 Journal Article A randomized trial of Nafamostat for Covid-19Morpeth, Susan C., Venkatesh, Balasubramanian, Totterdell, James A., McPhee, Grace M., Mahar, Robert K., Jones, Mark, Bandara, Methma, Barina, Lauren A., Basnet, Bhupendra K., Bowen, Asha C., Burke, Andrew J., Cochrane, Belinda, Denholm, Justin T., Dhungana, Ashesh, Dore, Gregory J., Dotel, Ravindra, Duffy, Eamon, Dummer, Jack, Foo, Hong, Gilbey, Timothy L., Hammond, Naomi E., Hudson, Bernard J., Jha, Vivekanand, Jevaji, Purnima R., John, Oommen, Joshi, Rajesh, Kang, Gagandeep, Kaur, Baldeep, Kim, Seungtaek ... Tong, Steven Y.C. (2023). A randomized trial of Nafamostat for Covid-19. NEJM Evidence, 2 (11), EVIDoa2300132-11. doi: 10.1056/evidoa2300132 |
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2023 Journal Article Avoiding misclassification of acute kidney injury: timing is everythingLegg, Amy, Roberts, Jason A., Roberts, Matthew A., Cass, Alan, Davies, Jane, Tong, Steven Y. C. and Davis, Joshua S. (2023). Avoiding misclassification of acute kidney injury: timing is everything. Nephrology, 29 (2), 100-104. doi: 10.1111/nep.14246 |
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2023 Journal Article In silico evaluation of a vancomycin dosing guideline among adults with serious infectionsWilliams, Paul, Cotta, Menino Osbert, Abdul-Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A (2023). In silico evaluation of a vancomycin dosing guideline among adults with serious infections. Therapeutic Drug Monitoring, 45 (5), 631-636. doi: 10.1097/FTD.0000000000001102 |
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2023 Journal Article In vitro susceptibility testing of imipenem- relebactam and tedizolid against 102 Mycobacterium abscessus isolatesBurke, Andrew, Carter, Robyn, Tolson, Carla, Congdon, Jacob, Duplancic, Christine, Bursle, Evan, Bell, Scott C., Roberts, Jason A. and Thomson, Rachel (2023). In vitro susceptibility testing of imipenem- relebactam and tedizolid against 102 Mycobacterium abscessus isolates. International Journal of Antimicrobial Agents, 62 (4) 106938, 1-6. doi: 10.1016/j.ijantimicag.2023.106938 |
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2023 Journal Article Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgeryAlli, Ahmad, Paruk, Fathima, Roger, Claire, Lipman, Jeffrey, Calleemalay, Daren, Wallis, Steven C., Scribante, Juan, Richards, Guy A. and Roberts, Jason A. (2023). Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery. PLoS One, 18 (9) e0291425, 1-14. doi: 10.1371/journal.pone.0291425 |
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2023 Journal Article Transparent reporting of adaptive clinical trials using concurrently randomised cohortsMarschner, Ian C., Jones, Mark, Totterdell, James A., Mahar, Robert K., Snelling, Thomas L., Tong, Steven Y.C., Basnet, Bhupendra, Bowen, Asha, Davis, Joshua, Denholm, Justin, Hammond, Naomi, Jha, Vivekanand, McPhee, Grace, McQuilten, Zoe, Morpeth, Susan, O’Sullivan, Matthew, Paterson, David (ASCOT study group), Price, David, Rees, Megan, Roberts, Jason (ASCOT study group), Trask, Nanette, Venkatesh, Balasubramanian, Chunilal, Sanjeev, Curnow, Jennifer, John, Joseph, McFadyen, James, Medcalf, Robert, Merriman, Eileen, Tran, Huyen ... Australasian Covid-19 Trial (ASCOT) study group (2023). Transparent reporting of adaptive clinical trials using concurrently randomised cohorts. BMJ Medicine, 2 (1) e000497. doi: 10.1136/bmjmed-2023-000497 |
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2023 Journal Article An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept studyRamachandra, Srinivas Sulugodu, Sime, Fekade Bruck, Naicker, Saiyuri, Han, Pingping, Lee, Ryan S.B., Wallis, Steven C., Roberts, Jason A. and Ivanovski, Sašo (2023). An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study. Journal of Periodontology, 95 (4), 384-396. doi: 10.1002/JPER.23-0086 |
