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2025

Journal Article

Beta-lactam antibiotic administration in critically ill children with sepsis: an international survey of current practice

Raman, Sainath, Reddy, Rayna, de Souza, Daniela Carla, Cox, Renee, Le Marsney, Renate, Nallasamy, Karthi, Ramnarayan, Padmanabhan, Roberts, Jason A., Schlapbach, Luregn J., Gibbons, Kristen S., the Australian and New Zealand Intensive Care Society Paediatric Study Group, Kerig, Tatjana, Darvas, Jennifer, Festa, Marino, George, Shane, Balit, Corrine, Oberender, Felix, Erickson, Simon, Flores, Jenipher Chumbes, Charles, Karina, Waak, Michaela, Long, Debbie, Butt, Warwick, Delzoppo, Carmel, Gelbart, Ben, Masterson, Kate, Millar, Johnny, Ganeshalingam, Anusha, Sherring, Claire ... Smith, Vicky (2025). Beta-lactam antibiotic administration in critically ill children with sepsis: an international survey of current practice. Intensive Care Medicine – Paediatric and Neonatal, 3 (1) 18. doi: 10.1007/s44253-025-00075-4

Beta-lactam antibiotic administration in critically ill children with sepsis: an international survey of current practice

2025

Journal Article

Evaluation of the stability of tigecycline in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy

Wolie, Zenaw T., Unwin, Sean, Burke, Andrew, Won, Hayoung, Wallis, Steven C., Seaton, R Andrew, Gilchrist, Mark, Roberts, Jason A. and Sime, Fekade B. (2025). Evaluation of the stability of tigecycline in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy. JAC - Antimicrobial Resistance, 7 (3) dlaf074, dlaf074. doi: 10.1093/jacamr/dlaf074

Evaluation of the stability of tigecycline in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy

2025

Journal Article

Current practices in outpatient parenteral antimicrobial therapy programmes: an international multi-centre survey

Wolie, Zenaw T., Roberts, Jason A., López-Cortés, Luis Eduardo, Mirón-Rubio, Manuel, Pollard, James, Marizan Nor, Afra Nahdia, Abdul-Aziz, Mohd H., Jamieson, Conor, Seaton, R Andrew, Gilchrist, Mark and Sime, Fekade B. (2025). Current practices in outpatient parenteral antimicrobial therapy programmes: an international multi-centre survey. JAC - Antimicrobial Resistance, 7 (3) dlaf075, 1-11. doi: 10.1093/jacamr/dlaf075

Current practices in outpatient parenteral antimicrobial therapy programmes: an international multi-centre survey

2025

Journal Article

Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy

Goetz, Katharina M., Kreuer, Sascha, Volz, Anke-Katrin, Parker, Suzanne L., Roberts, Jason A., Dimopoulos, George, Dimski, Thomas, Kindgen-Milles, Detlef, Beuche, Lisa K. V., Kielstein, Jan T. and Lehr, Thorsten (2025). Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy. Antimicrobial Agents and Chemotherapy, 69 (6) e0177924, 1-16. doi: 10.1128/aac.01779-24

Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy

2025

Journal Article

Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients

Kumta, Nilesh, Heffernan, Aaron J., Liu, Xin, Parker, Suzanne L., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wai, Wong Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2025). Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients. International Journal of Antimicrobial Agents, 65 (5) 107461, 107461. doi: 10.1016/j.ijantimicag.2025.107461

Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients

2025

Journal Article

Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis

Tognolini, Angela R., Liu, Xin, Pandey, Saurabh, Roberts, Jason A., Wallis, Steven C., Jackson, Dwane and Eley, Victoria A. (2025). Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis. Anaesthesia, 80 (5), 511-521. doi: 10.1111/anae.16531

Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis

2025

Journal Article

Development of methods to produce SARS CoV-2 virus-like particles at scale

Edeling, Melissa A., Earnest, Linda, Carrera Montoya, Julio, Yap, Ashley Huey Yiing, Mumford, Jamie, Roberts, Jason, Wong, Chinn Yi, Hans, Dhiraj, Grima, Joseph, Bisset, Nicole, Bodle, Jesse, Rockman, Steven and Torresi, Joseph (2025). Development of methods to produce SARS CoV-2 virus-like particles at scale. Biotechnology and Bioengineering, 122 (5), 1118-1129. doi: 10.1002/bit.28937

Development of methods to produce SARS CoV-2 virus-like particles at scale

2025

Journal Article

Population pharmacokinetic modelling of remdesivir and its metabolite GS-441524 in hospitalised patients with COVID-19

Roberts, Darren M., Liu, Xin, Parker, Suzanne L., Burke, Andrew, Peek, Jenny, Carland, Jane E., Murnion, Bridin, Seah, Vincent, Wallis, Steven C., Sumi, Chandra D., Pandey, Saurabh, Buscher, Hergen, Byrne, Anthony, Sandaradura, Indy, Bowen, David, Holz, Simon, Stewart, Adam G., Hajkowicz, Krispin M. and Roberts, Jason A. (2025). Population pharmacokinetic modelling of remdesivir and its metabolite GS-441524 in hospitalised patients with COVID-19. Clinical Pharmacokinetics, 64 (5) e0022222, 743-756. doi: 10.1007/s40262-025-01496-2

Population pharmacokinetic modelling of remdesivir and its metabolite GS-441524 in hospitalised patients with COVID-19

2025

Journal Article

Correction of posaconazole concentrations for hypoalbuminemia

Nix, David E., Sime, Fekade and Roberts, Jason A. (2025). Correction of posaconazole concentrations for hypoalbuminemia. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 45 (6), 324-331. doi: 10.1002/phar.70021

Correction of posaconazole concentrations for hypoalbuminemia

2025

Journal Article

A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult Populations

Zamri, Puteri Juanita, Lim, Sazlyna Mohd Sazlly, Sime, Fekade Bruck, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2025). A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult Populations. Clinical Pharmacokinetics, 64 (5) n71, 1-35. doi: 10.1007/s40262-025-01488-2

A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult Populations

2025

Journal Article

Optimising peri-operative intravenous lidocaine dosing regimens

Tognolini, Angela, Roberts, Jason A. and Eley, Victoria A. (2025). Optimising peri-operative intravenous lidocaine dosing regimens. Anaesthesia, 80 (7), 873-873. doi: 10.1111/anae.16611

Optimising peri-operative intravenous lidocaine dosing regimens

2025

Journal Article

Pharmacokinetics of metronidazole during prolonged intermittent kidney replacement therapy

Xu, Jessica H., Cheng, Vesa, Rawlins, Matthew, Morgan, David, Won, Hayoung, Wu, Xiaolin, Dyer, John and Roberts, Jason A. (2025). Pharmacokinetics of metronidazole during prolonged intermittent kidney replacement therapy. Hemodialysis International, 29 (4) 0310057X251396229, 713-716. doi: 10.1111/hdi.13242

Pharmacokinetics of metronidazole during prolonged intermittent kidney replacement therapy

2025

Journal Article

Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis

Mohammed, Solomon Ahmed, Roberts, Jason A., Mirón-Rubio, Manuel, López Cortés, Luis Eduardo, Assefa, Getnet Mengistu, Pollard, James, McCarthy, Kate, Gilchrist, Mark, Cotta, Menino and Sime, Fekade B. (2025). Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis. JAC-Antimicrobial Resistance, 7 (2) dlaf049, 1-11. doi: 10.1093/jacamr/dlaf049

Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis

2025

Journal Article

Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply

Hernández-Mitre, María Patricia, Roberts, Jason A. and Roger, Claire (2025). Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply. Intensive Care Medicine, 51 (4), 1-2. doi: 10.1007/s00134-025-07872-7

Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply

2025

Journal Article

Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial

Eley, Victoria A., Navarro, Severine, Martin, Elizabeth, Amoako, Akwasi, Hartel, Gunter, Woods, Christine, Lu, Yan, Lipman, Jeffrey, Roberts, Jason, Tang, Mimi and Callaway, Leonie (2025). Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial. BMC Pregnancy and Childbirth, 25 (1) 353, 1-11. doi: 10.1186/s12884-025-07484-5

Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial

2025

Journal Article

In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: a cross-sectional study’

Angelini, Jacopo, Giuliano, Simone, Lanini, Simone, Ferin, Sara, Martini, Luca, Cossettini, Stella, Roberts, Jason, Baraldo, Massimo and Tascini, Carlo (2025). In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: a cross-sectional study’. International Journal of Antimicrobial Agents, 65 (6) 107480, 107480. doi: 10.1016/j.ijantimicag.2025.107480

In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: a cross-sectional study’

2025

Journal Article

Population pharmacokinetics and dosing simulations of temocillin in liver-transplanted paediatric patients: a prospective, open-label, non-randomized study

Ngougni Pokem, Perrin, Stéphenne, Xavier, Liu, Xin, Parker, Suzanne L., Van der Linden, Dimitri, Godet, Marie-Laura, Wijnant, Gert-Jan, Chatzis, Olga, Houtekie, Laurent, Haenecour, Astrid, Sokal, Etienne, Roberts, Jason A., Elens, Laure and Van Bambeke, Françoise (2025). Population pharmacokinetics and dosing simulations of temocillin in liver-transplanted paediatric patients: a prospective, open-label, non-randomized study. Clinical Microbiology and Infection, 31 (3), 408-416. doi: 10.1016/j.cmi.2024.12.015

Population pharmacokinetics and dosing simulations of temocillin in liver-transplanted paediatric patients: a prospective, open-label, non-randomized study

2025

Journal Article

Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial

Mahar, Robert K., McGlothlin, Anna, Dymock, Michael, Barina, Lauren, Bonten, Marc, Bowen, Asha, Cheng, Matthew P., Daneman, Nick, Goodman, Anna L., Lee, Todd C., Lewis, Roger J., Lumley, Thomas, McLean, Alistair R. D., McQuilten, Zoe, Mora, Jocelyn, Paterson, David L., Price, David J., Roberts, Jason, Snelling, Tom, Tverring, Jonas, Webb, Steve A., Yahav, Dafna, Davis, Joshua S., Tong, Steven Y. C., Marsh, Julie A., on behalf of the SNAP Global Trial Steering Committee, Boyles, Tom, Cosgrove, Catherine, Heriot, George ... Whiteway, Lynda (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, 26 (1) 49, 1-7. doi: 10.1186/s13063-024-08684-8

Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial

2025

Journal Article

Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study

Roberts, Jason A., Sime, Fekade B., Lipman, Jeffrey, Hernández-Mitre, María Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Ceccarelli, Giancarlo, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2025). Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study. Intensive Care Medicine, 51 (2), 1-16. doi: 10.1007/s00134-025-07793-5

Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study

2025

Journal Article

Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?

Heffernan, Aaron J. and Roberts, Jason A. (2025). Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?. Journal of Critical Care, 85 154934, 154934. doi: 10.1016/j.jcrc.2024.154934

Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?