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2025 Journal Article Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administrationMurray, Fionnuala, Yoo, Okhee, Brophy-Williams, Samuel, Rawlins, Matthew, Wallis, Steven C., Roberts, Jason A., Raby, Edward, Salman, Sam and Manning, Laurens (2025). Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration. Journal of Antimicrobial Chemotherapy, 80 (2), 347-353. doi: 10.1093/jac/dkae397 |
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2025 Journal Article Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?Heffernan, Aaron J. and Roberts, Jason A. (2025). Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?. Journal of Critical Care, 85 154934, 154934. doi: 10.1016/j.jcrc.2024.154934 |
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2025 Journal Article Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO studyAbdul-Aziz, Mohd H., Diehl, Arne, Liu, Xin, Cheng, Vesa, Corley, Amanda, Gilder, Eileen, Levkovich, Bianca, McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Pellegrino, Vincent, Wallis, Steven C., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2025). Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 69 (2) e0143524, 1-15. doi: 10.1128/aac.01435-24 |
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2025 Journal Article Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infectionGiuliano, Simone, Angelini, Jacopo, Campanile, Floriana, Conti, Paola, Flammini, Sarah, Pagotto, Alberto, Sbrana, Francesco, Martini, Luca, D'Elia, Denise, Abdul-Aziz, Mohd H., Cotta, Menino O., Roberts, Jason A., Bonomo, Robert A. and Tascini, Carlo (2025). Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection. Scientific Reports, 15 (1) 3519, 1-16. doi: 10.1038/s41598-025-87512-8 |
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2025 Journal Article A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)Gurunathan, Usha, Medcalf, Robert L., Chiang, Lily, Liu, Zikou, Liu, Xin, Keragala, Charithani B., Hernandez-Mitre, Maria Patricia, Brady, Paul, Wallis, Steven C., Roberts, Jason A., Mullany, Daniel, Nandurkar, Harshal, Eley, Victoria and Parker, Suzanne L. (2025). A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE). British Journal of Anaesthesia. doi: 10.1016/j.bja.2024.12.004 |
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2025 Journal Article Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]Hernández-Mitre, María Patricia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y.C. and Roberts, Jason A. (2025). Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]. Clinical Microbiology and Infection, 31 (1) 141, 141-141. doi: 10.1016/j.cmi.2024.08.005 |
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2025 Journal Article A fluconazole population pharmacokinetics study to improve target attainment in critically ill patientsVuong, My-Luong, Elkayal, Omar, Van Daele, Ruth, Alffenaar, Jan-Willem C., Stocker, Sophie L., Roberts, Jason A., Debaveye, Yves, Wauters, Joost, Mertens, Beatrijs, Boonstra, Jasper M., Sandaradura, Indy, Marriott, Deborah J. E., Brüggemann, Roger J., Schouten, Jeroen A., Bergner, Raoul, Buijk, Steven, Spriet, Isabel and Dreesen, Erwin (2025). A fluconazole population pharmacokinetics study to improve target attainment in critically ill patients. Infection, 54 (1), 299-313. doi: 10.1007/s15010-025-02663-0 |
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2025 Journal Article Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluationBassetti, Matteo, Stewart, Adam, Bartalucci, Claudia, Vena, Antonio, Giacobbe, Daniele Roberto and Roberts, Jason (2025). Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation. Expert Opinion On Drug Metabolism and Toxicology, 21 (2), 125-132. doi: 10.1080/17425255.2024.2424899 |
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2025 Journal Article Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administrationMurray, Fionnuala, Yoo, Okhee, Brophy-Williams, Samuel, Rawlins, Matthew, Wallis, Steven C., Roberts, Jason A., Raby, Edward, Salman, Sam and Manning, Laurens (2025). Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administration. Journal of Antimicrobial Chemotherapy, 80 (1), 209-215. doi: 10.1093/jac/dkae398 |
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2025 Journal Article The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustmentsMärtson, Anne-Grete, Barber, Katie E, Crass, Ryan L, Hites, Maya, Kloft, Charlotte, Kuti, Joseph L, Nielsen, Elisabet I, Pai, Manjunath P, Zeitlinger, Markus, Roberts, Jason A and Tängdén, Thomas (2025). The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments. The Lancet Infectious Diseases, 25 (9), e504-e515. doi: 10.1016/S1473-3099(25)00155-0 |
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2025 Journal Article Evaluation of the stability of aciclovir in elastomeric infusion devices used for outpatient parenteral antimicrobial therapySime, Fekade Bruck, Wallis, Steven, Jamieson, Conor, Hills, Tim, Gilchrist, Mark, Santillo, Mark, Seaton, R Andrew, Drummond, Felicity and Roberts, Jason (2025). Evaluation of the stability of aciclovir in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy. European Journal of Hospital Pharmacy, 32 (3), 272-277. doi: 10.1136/ejhpharm-2023-003784 |
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2025 Journal Article Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studiesRouby, Jean-Jacques, Xia, Jing, Dhanani, Jayesh, Bassi, Gianluigi Li, Monsel, Antoine, Torres, Antoni, Arvaniti, Kostoula, Assefi, Mona, Bassetti, Matteo, Blot, Stijn, Boisson, Matthieu, Bouglé, Adrien, Constantin, Jean-Michel, Dimopoulos, George, Dugernier, Jonathan, Dureau, Pauline, Ehrmann, Stephan, Felton, Timothy, Kollef, Marin, Koutsoukou, Antonia, Kyriakoudi, Anna, Laterre, Pierre-François, Leone, Marc, Lepère, Victoria, Liao, Xuelian, Mishra, Shakti Bedanta, Mimoz, Olivier, Nair, Girish B, Niederman, Michael ... Zhu, Ying-gang (2025). Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies. Journal of Intensive Medicine, 5 (1), 12-22. doi: 10.1016/j.jointm.2024.07.006 |
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2024 Journal Article Prolonged vs intermittent infusions of β-lactam antibiotics-replyRoberts, Jason A., Devaux, Anthony and Abdul-Aziz, Mohd H. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics-reply. JAMA-Journal of the American Medical Association, 333 (3), 259. doi: 10.1001/jama.2024.23728 |
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2024 Journal Article A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations: From premature infants to the elderlyKong, Daming, Roberts, Jason A., Lipman, Jeffrey, Taccone, Fabio Silvio, Cohen-Wolkowiez, Michael, Sime, Fekade B., Tsai, Danny, De Cock, Pieter A. J. G., Jaruratanasirikul, Sutep, Dhaese, Sofie A. M., Udy, Andrew A., Felton, Timothy W., Michelet, Robin, Thibault, Celine, Koomen, Jeroen V., Eleveld, Douglas J., Struys, Michel M. R. F., De Waele, Jan J., Colin, Pieter J., Damen, Caroline and PIP/TAZ Consortium (2024). A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations: From premature infants to the elderly. Clinical Pharmacokinetics, 64 (1) 769329, 107-126. doi: 10.1007/s40262-024-01460-6 |
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2024 Journal Article Population pharmacokinetics of piperacillin-tazobactam in the plasma and cerebrospinal fluid of critically ill patientsKumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Liu, Xin, Parker, Suzanne, Wallis, Steven, Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2024). Population pharmacokinetics of piperacillin-tazobactam in the plasma and cerebrospinal fluid of critically ill patients. Antimicrobial Agents and Chemotherapy, 69 (2), e0060124. doi: 10.1128/aac.00601-24 |
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2024 Journal Article A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteriaAssefa, Getnet M., Roberts, Jason A., Aslan, Abdullah T., Mohammed, Solomon A. and Sime, Fekade B. (2024). A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy, 80 (2), 334-346. doi: 10.1093/jac/dkae451 |
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2024 Journal Article Continuous vs intermittent β-lactam antibiotic infusions for sepsis-ReplyDulhunty, Joel M., Roberts, Jason A. and Lipman, Jeffrey (2024). Continuous vs intermittent β-lactam antibiotic infusions for sepsis-Reply. JAMA: The Journal of the American Medical Association, 333 (2), 174-175. doi: 10.1001/jama.2024.23275 |
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2024 Journal Article Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et alBarton, Greg, Rickard, Claire M. and Roberts, Jason A. (2024). Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et al. Intensive Care Medicine, 51 (1), 230-231. doi: 10.1007/s00134-024-07724-w |
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2024 Journal Article Dynamic in vitro PK/PD infection models for the development and optimisation of antimicrobial regimens: A narrative reviewWale, Yalew M., Roberts, Jason A. and Sime, Fekade B. (2024). Dynamic in vitro PK/PD infection models for the development and optimisation of antimicrobial regimens: A narrative review. Antibiotics, 13 (12) 1201, 1-23. doi: 10.3390/antibiotics13121201 |
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2024 Journal Article Renal function and its impact on the concentration of ceftazidime-avibactam: a cross-sectional studyLanini, Simone, Giuliano, Simone, Angelini, Jacopo, Ferin, Sara, Martini, Luca, Baraldo, Massimo, Cossettini, Stella, Roberts, Jason and Tascini, Carlo (2024). Renal function and its impact on the concentration of ceftazidime-avibactam: a cross-sectional study. International Journal of Antimicrobial Agents, 64 (6) 107351, 1-6. doi: 10.1016/j.ijantimicag.2024.107351 |
