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2026 Journal Article The biology of endosomal escape: strategies for enhanced delivery of therapeuticsChahal, G. S., Helbig, K. J., Parton, R. G. and Monson, E. A. (2026). The biology of endosomal escape: strategies for enhanced delivery of therapeutics. ACS Nano, 20 (2) acsnano.5c18112, 1789-1813. doi: 10.1021/acsnano.5c18112 |
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2025 Journal Article A modular encapsulation system for precision delivery of proteins, nucleic acids, and small moleculesLuong, Thai D., Martel, Nick, Rae, James, Lo, Harriet P., Lim, Ye-Wheen, Wu, Yeping, McMahon, Kerrie-Ann, Sun, Haolan, Fletcher, Nicholas L., Thurecht, Kristofer J., Johnston, Angus P. R., Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2025). A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules. ACS Nano, 19 (50), 42079-42096. doi: 10.1021/acsnano.5c11452 |
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2025 Journal Article Targeted glycophagy ATG8 therapy reverses diabetic heart disease in mice and in human engineered cardiac tissuesMellor, K. M., Varma, U., Koutsifeli, P., Curl, C. L., Janssens, J. V., Daniels, L. J., Bernasochi, G. B., Raaijmakers, A. J. A., Annandale, M., Li, X., James, S. L., Taylor, D. J., Raedschelders, K., Weeks, K. L., Mills, R. J., Parton, R. G., Hu, X., Bell, J. R., O’Brien, T. J., Katare, R., Porrello, E. R., Hudson, J. E., Xiao, R. P., Van Eyk, J. E., Gottlieb, R. A. and Delbridge, L. M. D. (2025). Targeted glycophagy ATG8 therapy reverses diabetic heart disease in mice and in human engineered cardiac tissues. Nature Cardiovascular Research, 4 (11), 1487-1500. doi: 10.1038/s44161-025-00726-x |
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2025 Journal Article An efficient eukaryotic cell-free expression and correlative cryo-electron tomography platform for structural biology of macromolecular complexesTillu, Vikas, Hunter, Dominic, Chen, Kai-En, Smith, Jessica, Rae, James, Sierecki, Emma, Kobe, Bostjan, Gambin, Yann, Collins, Brett, Parton, Robert and Ariotti, Nicholas (2025). An efficient eukaryotic cell-free expression and correlative cryo-electron tomography platform for structural biology of macromolecular complexes. bioRxiv. doi: 10.1101/2025.10.18.683253 |
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2025 Journal Article A model for membrane curvature generation by caveolin discs driven by differential contact interactionBarnoy, Avishai, Ariotti, Nicholas, Parton, Robert G. and Kozlov, Michael M. (2025). A model for membrane curvature generation by caveolin discs driven by differential contact interaction. Nature Communications, 16 (1) 9030, 1-12. doi: 10.1038/s41467-025-64084-9 |
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2025 Journal Article Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophagesAbrol, Rishika, Afroz, Syeda Farhana, Curson, James E. B., Raven, Karoline D., Das Gupta, Kaustav, Gunther, Kimberley S., Jones, Alun, Reid, Robert C., Xiong, Zherui, Gunter, Jennifer H., Engel, Jessica A., Engwerda, Christian R., Blumenthal, Antje, Fairlie, David P., Parton, Robert G., Zuryn, Steven, Kapetanovic, Ronan, Ramnath, Divya and Sweet, Matthew J. (2025). Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages. Journal of Cell Science, 138 (19) jcs.264376, 1-14. doi: 10.1242/jcs.264376 |
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2025 Journal Article Editorial Overview - Membrane traffic; orchestrating the symphony of lifeParton, Robert G. and Weisman, Lois S. (2025). Editorial Overview - Membrane traffic; orchestrating the symphony of life. Current Opinion in Cell Biology, 95 102532, 102532-95. doi: 10.1016/j.ceb.2025.102532 |
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2025 Journal Article Co‐cultivation with new glucose‐sparing Chlorella algae boosts tissue culture efficiency by reducing cell wasteOey, Melanie, Marx, Ute, Schirra, Horst Joachim, Ross, Ian L., Parton, Robert G., Hankamer, Ben and Lo, Harriet P. (2025). Co‐cultivation with new glucose‐sparing Chlorella algae boosts tissue culture efficiency by reducing cell waste. Biotechnology Journal, 20 (7) e70067, 1-13. doi: 10.1002/biot.70067 |
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2025 Journal Article Maturation of human cardiac organoids enables complex disease modeling and drug discoveryPocock, Mark W., Reid, Janice D., Robinson, Harley R., Charitakis, Natalie, Krycer, James R., Foster, Simon R., Fitzsimmons, Rebecca L., Lor, Mary, Devilée, Lynn A. C., Batho, Christopher A. P., Tuano, Natasha, Howden, Sara E., Vlahos, Katerina, Watt, Kevin I., Piers, Adam T., Bibby, Kaitlyn, McNamara, James W., Sutton, Rebecca, Iaprintsev, Valerii, Mathew, Jacob, Voges, Holly K., Fortuna, Patrick R. J., Bass-Stringer, Sebastian, Vivien, Celine, Rae, James, Parton, Robert G., Firulli, Anthony B., Lisowski, Leszek, Huckstep, Hannah ... Hudson, James E. (2025). Maturation of human cardiac organoids enables complex disease modeling and drug discovery. Nature Cardiovascular Research, 4 (7), 821-840. doi: 10.1038/s44161-025-00669-3 |
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2025 Journal Article Pro-ferroptotic lipids as key control points for caveola formation and disassemblyWu, Yeping, Lim, Ye-Wheen, McMahon, Kerrie-Ann, Martel, Nick, Rae, James, Lo, Harriet P., Gao, Ya, Tillu, Vikas, Larsson, Elin, Lundmark, Richard, Levic, Daniel S., Bagnat, Michel, Lim, Junxian, Fairlie, David P., Pol, Albert, Collins, Brett M., Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2025). Pro-ferroptotic lipids as key control points for caveola formation and disassembly. Cell Reports, 44 (6) 115789, 115789. doi: 10.1016/j.celrep.2025.115789 |
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2025 Journal Article Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domainGao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-en, Weeratunga, Saroja, Guo, Qian, Livingstone, Emma, Tham, Wai-Hong, Parton, Robert G. and Collins, Brett M. (2025). Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain. Journal of Cell Science, 138 (8) 263756. doi: 10.1242/jcs.263756 |
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2025 Journal Article Single molecule visualization of tropomyosin isoform organization in the mammalian actin cytoskeletonCagigas, Maria L., Ariotti, Nicholas, Hook, Jeff, Rae, James, Parton, Robert G., Bryce, Nicole S., Gunning, Peter W. and Hardeman, Edna C. (2025). Single molecule visualization of tropomyosin isoform organization in the mammalian actin cytoskeleton. Cytoskeleton, 82 (1-2), 45-54. doi: 10.1002/cm.21883 |
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2025 Journal Article Erratum: Author Correction: An endosomal tether undergoes an entropic collapse to bring vesicles together (Nature (2012) 484 7393 DOI: 10.1038/nature10923)Murray, David H., Jahnel, Marcus, Lauer, Janelle, Avellaneda, Mario J., Brouilly, Nicolas, Cezanne, Alice, Morales-Navarrete, Hernán, Perini, Enrico D., Ferguson, Charles, Lupas, Andrei N., Kalaidzidis, Yannis, Parton, Robert G., Grill, Stephan W. and Zerial, Marino (2025). Erratum: Author Correction: An endosomal tether undergoes an entropic collapse to bring vesicles together (Nature (2012) 484 7393 DOI: 10.1038/nature10923). Nature, 637 (8048), E29-E29. doi: 10.1038/s41586-024-08567-7 |
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2024 Journal Article Precision in situ cryo-correlative light and electron microscopy of optogenetically-positioned organellesTillu, Vikas A., Redpath, Gregory M. I., Rae, James, Ruan, Juanfang, Yao, Yin, Cagigas, Maria L., Whan, Renee, Hardeman, Edna C., Gunning, Peter W., Ananthanarayanan, Vaishnavi, Parton, Robert G. and Ariotti, Nicholas A. (2024). Precision in situ cryo-correlative light and electron microscopy of optogenetically-positioned organelles. Journal of Cell Science, 137 (20) jcs262163, 1-16. doi: 10.1242/jcs.262163 |
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2024 Journal Article The desmosome-intermediate filament system facilitates mechanotransduction at adherens junctions for epithelial homeostasisNanavati, Bageshri Naimish, Noordstra, Ivar, Lwin, Angela K.O., Brooks, John W., Rae, James, Parton, Robert G., Verma, Suzie, Duszyc, Kinga, Green, Kathleen J. and Yap, Alpha S. (2024). The desmosome-intermediate filament system facilitates mechanotransduction at adherens junctions for epithelial homeostasis. Current Biology, 34 (17), 4081-4090. doi: 10.1016/j.cub.2024.07.074 |
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2024 Conference Publication Apicobasal RNA asymmetries regulate cell fate in the early mouse embryoHawdon, A., Geoghegan, N. D., Mohenska, M., Elsenhans, A., Ferguson, C., Polo, J. M., Parton, R. G. and Zenker, J. (2024). Apicobasal RNA asymmetries regulate cell fate in the early mouse embryo. 40th Hybrid Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Amsterdam Netherlands, Jul 07-10, 2024. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/humrep/deae108.196 |
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2024 Journal Article Interview with Journal of Cell Science Editor Rob PartonParton, Rob (2024). Interview with Journal of Cell Science Editor Rob Parton. Journal of Cell Science, 137 (13) jcs262287. doi: 10.1242/jcs.262287 |
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2024 Journal Article Is endocytosis by caveolae dependent on dynamin?Parton, Robert G., Taraska, Justin W. and Lundmark, Richard (2024). Is endocytosis by caveolae dependent on dynamin?. Nature Reviews Molecular Cell Biology, 25 (7), 1-2. doi: 10.1038/s41580-024-00735-x |
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2024 Journal Article Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolismKeshvari, Sahar, Masson, Jesse J.R., Ferrari-Cestari, Michelle, Bodea, Liviu-Gabriel, Nooru-Mohamed, Fathima, Tse, Brian W.C., Sokolowski, Kamil A., Batoon, Lena, Patkar, Omkar L., Sullivan, Mitchell A., Ebersbach, Hilmar, Stutz, Cian, Parton, Robert G., Summers, Kim M., Pettit, Allison R., Hume, David A. and Irvine, Katharine M. (2024). Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism. American Journal of Physiology-Endocrinology and Metabolism, 326 (2), E149-E165. doi: 10.1152/ajpendo.00347.2023 |
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2024 Journal Article The Biology of LipidsParton, Robert G. and Simons, Kai (2024). The Biology of Lipids. Cold Spring Harbor Perspectives in Biology, 16 (8) a041713. doi: 10.1101/cshperspect.a041713 |
