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2020

Journal Article

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

2020

Journal Article

Caveolae and lipid sorting: shaping the cellular response to stress

Parton, Robert G., Kozlov, Michael M. and Ariotti, Nicholas (2020). Caveolae and lipid sorting: shaping the cellular response to stress. Journal of Cell Biology, 219 (4) e201905071. doi: 10.1083/jcb.201905071

Caveolae and lipid sorting: shaping the cellular response to stress

2020

Journal Article

Mapping interactions among cell-free expressed Zirka virus proteins

Varasteh Moradi, Shayli, Gagoski, Dejan, Mureev, Sergey, Walden, Patricia, McMahon, Kerrie-Ann, Parton, Robert G., Johnston, Wayne A. and Alexandrov, Kirill (2020). Mapping interactions among cell-free expressed Zirka virus proteins. Journal of Proteome Research, 19 (4) acs.jproteome.9b00771, 1522-1532. doi: 10.1021/acs.jproteome.9b00771

Mapping interactions among cell-free expressed Zirka virus proteins

2020

Journal Article

A role for caveola‐forming proteins caveolin‐1 and CAVIN1 in the pro‐invasive response of glioblastoma to osmotic and hydrostatic pressure

Pu, Wenjun, Qiu, Jiawen, Nassar, Zeyad D., Shaw, Paul N., McMahon, Kerrie‐Ann, Ferguson, Charles, Parton, Robert G., Riggins, Gregory J., Harris, Jonathan M. and Parat, Marie‐Odile (2020). A role for caveola‐forming proteins caveolin‐1 and CAVIN1 in the pro‐invasive response of glioblastoma to osmotic and hydrostatic pressure. Journal of Cellular and Molecular Medicine, 24 (6) jcmm.15076, 3724-3738. doi: 10.1111/jcmm.15076

A role for caveola‐forming proteins caveolin‐1 and CAVIN1 in the pro‐invasive response of glioblastoma to osmotic and hydrostatic pressure

2020

Journal Article

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development

Shohayeb, Belal, Ho, Uda, Yeap, Yvonne Y., Parton, Robert G., Millard, Sean S., Xu, Zhiheng, Piper, Michael and Ng, Dominic C. H. (2020). The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. Human Molecular Genetics, 29 (2), 248-263. doi: 10.1093/hmg/ddz281

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development

2020

Journal Article

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis

Bhattachan, Punit, Rae, James, Yu, Haiyan, Jung, WooRam, Wei, Jiankai, Parton, Robert G. and Dong, Bo (2020). Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. The FASEB Journal, 34 (1), 1345-1361. doi: 10.1096/fj.201901281R

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis

2020

Journal Article

Twenty years of Traffic

Marks, Michael S., Tooze, Sharon A., Brodsky, Frances M., Marsh, Mark, Parton, Robert G. and Schroer, Trina A. (2020). Twenty years of Traffic. Traffic, 21 (1), 4-5. doi: 10.1111/tra.12688

Twenty years of Traffic

2020

Journal Article

ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

Du, Ximing, Zhou, Linkang, Aw, Yvette Celine, Mak, Hoi Yin, Xu, Yanqing, Rae, James, Wang, Wenmin, Zadoorian, Armella, Hancock, Sarah E., Osborne, Brenna, Chen, Xiang, Wu, Jia-Wei, Turner, Nigel, Parton, Robert G., Li, Peng and Yang, Hongyuan (2020). ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets. The Journal of Cell Biology, 219 (1) jcb.201905162. doi: 10.1083/jcb.201905162

ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

2020

Journal Article

Caveolae control contractile tension for epithelia to eliminate tumor cells

Teo, Jessica L., Gomez, Guillermo A., Weeratunga, Saroja, Davies, Elizabeth M., Noordstra, Ivar, Budnar, Srikanth, Katsuno-Kambe, Hiroko, McGrath, Meagan J., Verma, Suzie, Tomatis, Vanesa, Acharya, Bipul R., Balasubramaniam, Lakshmi, Templin, Rachel M., McMahon, Kerrie-Ann, Lee, Yoke Seng, Ju, Robert J., Stebhens, Samantha J., Ladoux, Benoit, Mitchell, Christina A., Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2020). Caveolae control contractile tension for epithelia to eliminate tumor cells. Developmental Cell, 54 (1), 75-91.e7. doi: 10.1016/j.devcel.2020.05.002

Caveolae control contractile tension for epithelia to eliminate tumor cells

2020

Conference Publication

Reactivation of Myc transcription in the heart unlocks its proliferative capacity

Bywater, M. J., Burkhart, D. L., Sabo, A., Straube, J., Pendino, V., Hudson, J. E., Quaife-Ryan, G. A., Porrello, E. R., Rae, J., Parton, R. G., Kress, T. R., Amati, B., Littlewood, T. D., Evan, G. I. and Wilson, C. H. (2020). Reactivation of Myc transcription in the heart unlocks its proliferative capacity. BSCR Autumn meeting, New York, NY, United States: Springer.

Reactivation of Myc transcription in the heart unlocks its proliferative capacity

2020

Book Chapter

Live confocal imaging of zebrafish notochord cells under mechanical stress in vivo

Lim, Ye-Wheen, Lo, Harriet P., Hall, Thomas E. and Parton, Robert G. (2020). Live confocal imaging of zebrafish notochord cells under mechanical stress in vivo. Caveolae: methods and protocols. (pp. 175-187) edited by Cedric M. Blouin. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0732-9_16

Live confocal imaging of zebrafish notochord cells under mechanical stress in vivo

2020

Journal Article

Lipid droplets, bioenergetic fluxes, and metabolic flexibility

Bosch, Marta, Parton, Robert G. and Pol, Albert (2020). Lipid droplets, bioenergetic fluxes, and metabolic flexibility. Seminars in Cell and Developmental Biology, 108, 33-46. doi: 10.1016/j.semcdb.2020.02.010

Lipid droplets, bioenergetic fluxes, and metabolic flexibility

2019

Journal Article

An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation

Echarri, Asier, Pavón, Dácil M., Sánchez, Sara, García-García, María, Calvo, Enrique, Huerta-López, Carla, Velázquez-Carreras, Diana, Viaris de Lesegno, Christine, Ariotti, Nicholas, Lázaro-Carrillo, Ana, Strippoli, Raffaele, De Sancho, David, Alegre-Cebollada, Jorge, Lamaze, Christophe, Parton, Robert G. and Del Pozo, Miguel A. (2019). An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation. Nature Communications, 10 (1) 5828, 1-16. doi: 10.1038/s41467-019-13782-2

An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation

2019

Conference Publication

Nanoscapes: Authentic scales and densities in real-time 3D cinematic visualizations of cellular landscapes

Lilja, Andrew R., Kadir, Shereen R., Hughes, Rowan T., Gunn, Nicholas J., Strong, Campbell W., Bailey, Benjamin J., Parton, Robert G. and McGhee, John B. (2019). Nanoscapes: Authentic scales and densities in real-time 3D cinematic visualizations of cellular landscapes. Association for Computing Machinery, Inc. doi: 10.1145/3355056.3364567

Nanoscapes: Authentic scales and densities in real-time 3D cinematic visualizations of cellular landscapes

2019

Journal Article

Caveolae: the FAQs

Parton, Robert G., Pozo, Miguel A., Vassilopoulos, Stéphane, Nabi, Ivan R., Le Lay, Soazig, Lundmark, Richard, Kenworthy, Anne K., Camus, Anne, Blouin, Cedric M., Sessa, William C. and Lamaze, Christophe (2019). Caveolae: the FAQs. Traffic, 21 (1) tra.12689, 181-185. doi: 10.1111/tra.12689

Caveolae: the FAQs

2019

Journal Article

20 years of Traffic: a 2020 vision of cellular electron microscopy

Parton, Robert G (2019). 20 years of Traffic: a 2020 vision of cellular electron microscopy. Traffic, 21 (1) tra.12684, 156-161. doi: 10.1111/tra.12684

20 years of Traffic: a 2020 vision of cellular electron microscopy

2019

Journal Article

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

McMahon, Kerrie-Ann, Wu, Yeping, Gambin, Yann, Sierecki, Emma, Tillu, Vikas A., Hall, Thomas, Martel, Nick, Okano, Satomi, Moradi, Shayli Varasteh, Ruelcke, Jayde E., Ferguson, Charles, Yap, Alpha S., Alexandrov, Kirill, Hill, Michelle M. and Parton, Robert G. (2019). Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nature Communications, 10 (1) 3279, 3279. doi: 10.1038/s41467-019-11111-1

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

2019

Journal Article

Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres

Meiring, Joyce C. M., Bryce, Nicole S., Cagigas, Maria Lastra, Benda, Aleš, Whan, Renee M., Ariotti, Nicholas, Parton, Robert G., Stear, Jeffrey H., Hardeman, Edna C. and Gunning, Peter W. (2019). Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres. Journal of Cell Science, 132 (15) jcs228916, jcs.228916. doi: 10.1242/jcs.228916

Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres

2019

Journal Article

The membrane environment of cadherin adhesion receptors: a working hypothesis

Teo, Jessica L., Parton, Robert G. and Yap, Alpha S. (2019). The membrane environment of cadherin adhesion receptors: a working hypothesis. Biochemical Society Transactions, 47 (4), BST20180012-995. doi: 10.1042/bst20180012

The membrane environment of cadherin adhesion receptors: a working hypothesis

2019

Journal Article

Drug‐induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann–Pick type C cells and mice

Moreau, Dimitri, Vacca, Fabrizio, Vossio, Stefania, Scott, Cameron, Colaco, Alexandria, Paz Montoya, Jonathan, Ferguson, Charles, Damme, Markus, Moniatte, Marc, Parton, Robert G, Platt, Frances M and Gruenberg, Jean (2019). Drug‐induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann–Pick type C cells and mice. EMBO Reports, 20 (7) e47055, e47055. doi: 10.15252/embr.201847055

Drug‐induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann–Pick type C cells and mice