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2017

Journal Article

Correlative light and electron microscopic detection of GFP-labeled proteins using modular APEX

Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2017). Correlative light and electron microscopic detection of GFP-labeled proteins using modular APEX. Methods in Cell Biology, 140, 105-121. doi: 10.1016/bs.mcb.2017.03.002

Correlative light and electron microscopic detection of GFP-labeled proteins using modular APEX

2017

Journal Article

Mammalian diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility

Acharya, Bipul R., Wu, Selwin K., Lieu, Zi Zhao, Parton, Robert G., Grill, Stephan W., Bershadsky, Alexander D., Gomez, Guillermo A. and Yap, Alpha S. (2017). Mammalian diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility. Cell Reports, 18 (12), 2854-2867. doi: 10.1016/j.celrep.2017.02.078

Mammalian diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility

2017

Journal Article

Development of a human cardiac organoid injury model reveals innate regenerative potential

Voges, Holly K., Mills, Richard J., Elliott, David A., Parton, Robert G., Porrello, Enzo R. and Hudson, James E. (2017). Development of a human cardiac organoid injury model reveals innate regenerative potential. Development, 144 (6), 1118-1127. doi: 10.1242/dev.143966

Development of a human cardiac organoid injury model reveals innate regenerative potential

2017

Journal Article

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

Kerr, Markus C., Gomez, Guillermo A., Ferguson, Charles, Tanzer, Maria C., Murphy, James M., Yap, Alpha S., Parton, Robert G., Huston, Wilhelmina M. and Teasdale, Rohan D. (2017). Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis. Nature Communications, 8 (1) 14729, 14729. doi: 10.1038/ncomms14729

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

2017

Journal Article

A plasmid library of full-length zebrafish rab proteins forcell biology

Hall, Thomas E., Martel, Nick, Lo, Harriet P., Xiong, Zherui and Parton, Robert G. (2017). A plasmid library of full-length zebrafish rab proteins forcell biology. Cellular Logistics, 7 (1), 1-5. doi: 10.1080/21592799.2017.1301151

A plasmid library of full-length zebrafish rab proteins forcell biology

2017

Conference Publication

A Microtubule Organizing Center Directing Intracellular Transport in the Early Mouse Embryo

Zenker, J., White, M. D., Templin, R. M., Parton, R. G., Thorn-Seshold, O., Bissiere, S. and Plachta, N. (2017). A Microtubule Organizing Center Directing Intracellular Transport in the Early Mouse Embryo. ASCB/EMBO Meeting, Philadelphia Pa United States, 2-6 December 2017. Bethesda, MD United States: American Society for Cell Biology.

A Microtubule Organizing Center Directing Intracellular Transport in the Early Mouse Embryo

2017

Conference Publication

A distinct plasma lipid signature associated with poor prognosis in castration-resistant prostate cancer

Horvath, Lisa, Lin, Hui-Ming, Mahon, Kate, Weir, Jacquelyn, Mundra, Piyushkumar, Spielman, Calan, Briscoe, Karen, Gurney, Howard, Mallesara, Girish, Marx, Gavin, Stockler, Martin, Parton, Robert, Hoy, Andrew, Daly, Roger and Meikle, Peter (2017). A distinct plasma lipid signature associated with poor prognosis in castration-resistant prostate cancer. ANZUP Annual Scientific Meeting: The Art & Science of Best Practice, Melbourne, VIC, Australia, 16–18 July 2017. Hoboken, NJ, United States: Wiley. doi: 10.1111/ajco.12718

A distinct plasma lipid signature associated with poor prognosis in castration-resistant prostate cancer

2017

Conference Publication

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Hudson, J., Mills, R., Titmarsh, D., Koenig, X., Parker, B., Ryall, J., Quaife-Ryan, G., Voges, H., Hodson, M., Ferguson, C., Drowley, L., Plowright, A., Wang, Q., Gregorevic, P., Xin, M., Thomas, W., Parton, R., Nielsen, L., Launikonis, B., James, D., Elliott, D. and Porrello, E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Abstracts for the 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Perth, Australia, 10 - 13 August 2017. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2017.06.375

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

2016

Journal Article

Unraveling the architecture of caveolae

Parton, Robert G. and Collins, Brett M. (2016). Unraveling the architecture of caveolae. Proceedings of the National Academy of Sciences, 113 (50), 14170-14172. doi: 10.1073/pnas.1617954113

Unraveling the architecture of caveolae

2016

Journal Article

Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence

Sierecki, Emma, Giles, Nichole, Bowden, Quill, Polinkovsky, Mark E., Steinbeck, Janina, Arrioti, Nicholas, Rahman, Diya, Bhumkar, Akshay, Nicovich, Philip R., Ross, Ian, Parton, Robert G., Bocking, Till and Gambin, Yann (2016). Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence. Scientific Reports, 6 (1) 37630, 37630. doi: 10.1038/srep37630

Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence

2016

Journal Article

SEIPIN regulates lipid droplet expansion and adipocyte development by modulating the activity of glycerol-3-phosphate acyltransferase

Pagac, Martin, Cooper, Daniel E., Qi, Yanfei, Lukmantara, Ivan E., Mak, Hoi Yin, Wu, Zengying, Tian, Yuan, Liu, Zhonghua, Lei, Mona, Du, Ximing, Ferguson, Charles, Kotevski, Damian, Sadowski, Pawel, Chen, Weiqin, Boroda, Salome, Harris, Thurl E., Liu, George, Parton, Robert G., Huang, Xun, Coleman, Rosalind A. and Yang, Hongyuan (2016). SEIPIN regulates lipid droplet expansion and adipocyte development by modulating the activity of glycerol-3-phosphate acyltransferase. Cell Reports, 17 (6), 1546-1559. doi: 10.1016/j.celrep.2016.10.037

SEIPIN regulates lipid droplet expansion and adipocyte development by modulating the activity of glycerol-3-phosphate acyltransferase

2016

Journal Article

Erratum: Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Pageon, Sophie V. , Tabarin, Thibault , Yamamoto, Yui , Ma, Yuanqing , Nicovich, Philip R. , Bridgeman, John S. , Cohnen, André , Benzing, Carola , Gao, Yijun , Crowther, Michael D. , Tungatt, Katie , Dolton, Garry , Sewell, Andrew K. , Price, David A. , Acuto, Oreste , Parton, Robert G. , Gooding, Justin , Rossy, Jérémie, Rossjohn, Jamie and Gaus, Katharina (2016). Erratum: Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences of the United States of America , 113 (44), e6905-e6905. doi: 10.1073/pnas.1615763113

Erratum: Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

2016

Journal Article

Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles

Joensuu, Merja, Padmanabhan, Pranesh, Durisic, Nela, Bademosi, Adekunle T. D., Cooper-Williams, Elizabeth, Morrow, Isabel C., Harper, Callista B., Jung, WooRam, Parton, Robert G., Goodhill, Geoffrey J., Papadopulos, Andreas and Meunier, Frederic A. (2016). Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles. Journal of Cell Biology, 215 (2), 277-292. doi: 10.1083/jcb.201604001

Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles

2016

Journal Article

Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation

Chai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016). Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. The Journal of Cell Biology, 214 (6) 705, 705-718. doi: 10.1083/jcb.201512016

Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation

2016

Journal Article

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuangqing, Nicovich, Philip R., Bridgeman, John S., Cohnen, André, Benzing, Carola, Gao, Yijun, Crowther, Michael D., Tungatt, Katie, Dolton, Garry, Sewell, Andrew K., Price, David A., Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jérémie, Rossjohn, Jamie and Gaus, Katharina (2016). Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences of the United States of America, 113 (37), E5454-E5463*. doi: 10.1073/pnas.1607436113

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

2016

Journal Article

Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation

Follett, Jordan, Bugarcic, Andrea, Yang, Zhe, Ariotti, Nicholas, Norwood, Suzanne J., Collins, Brett M., Parton, Robert G. and Teasdale, Rohan D. (2016). Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation. Journal of Biological Chemistry, 291 (35), 18283-18298. doi: 10.1074/jbc.M115.703157

Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation

2016

Journal Article

An endosomal tether undergoes an entropic collapse to bring vesicles together

Murray, David H., Jahnel, Marcus, Lauer, Janelle, Avellaneda, Mario J., Brouilly, Nicolas, Cezanne, Alice, Morales-Navarrete, Hernan, Perini, Enrico D., Ferguson, Charles, Lupas, Andrei N., Kalaidzidis, Yannis, Parton, Robert G., Grill, Stephan W. and Zerial, Marino (2016). An endosomal tether undergoes an entropic collapse to bring vesicles together. Nature, 537 (7618), 107-111. doi: 10.1038/nature19326

An endosomal tether undergoes an entropic collapse to bring vesicles together

2016

Journal Article

Corrigendum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

Takasato, Minoru, Er, Pei X., Chiu, Han S., Maier, Barbara, Baillie, Gregory J., Ferguson, Charles, Parton, Robert G., Wolvetang, Ernst J., Roost, Matthias S., Lopes, Susana M. Chuva de Sousa and Little, Melissa H. (2016). Corrigendum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 536 (7615), 238-238. doi: 10.1038/nature17982

Corrigendum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

2016

Journal Article

A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C

Makino, Asami, Abe, Mitsuhiro, Ishitsuka, Reiko, Murate, Motohide, Kishimoto, Takuma, Sakai, Shota, Hullin-Matsuda, Françoise, Shimada, Yukiko, Inaba, Takehiko, Miyatake, Hideyuki, Tanaka, Hideko, Kurahashi, Atsushi, Pack, Chan-Gi, Kasai, Rinshi S., Kubo, Shuku, Schieber, Nicole L., Dohmae, Naoshi, Tochio, Naoya, Hagiwara, Kyoji, Sasaki, Yutaka, Aida, Yoko, Fujimori, Fumihiro, Kigawa, Takanori, Nishibori, Kozo, Parton, Robert G., Kusumi, Akihiro, Sako, Yasushi, Anderluh, Gregor, Yamashita, Makoto ... Kobayashi, Toshihide (2016). A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C. FASEB Journal, 31 (4), 1301-1322. doi: 10.1096/fj.201500075R

A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C

2016

Journal Article

Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling

Humphrey, Emily S., Su, Shih-Ping, Nagrial, Adnan M., Hochgraefe, Falko, Pajic, Marina, Lehrbach, Gillian M., Parton, Robert G., Yap, Alpha S., Horvath, Lisa G., Chang, David K., Biankin, Andrew V., Wu, Jianmin and Daly, Roger J. (2016). Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling. Molecular and Cellular Proteomics, 15 (8), 2671-2685. doi: 10.1074/mcp.M116.058313

Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling