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2021 Journal Article Key principles and methods for studying the endocytosis of biological and nanoparticle therapeuticsRennick, Joshua J., Johnston, Angus P. R. and Parton, Robert G. (2021). Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics. Nature Nanotechnology, 16 (3), 266-276. doi: 10.1038/s41565-021-00858-8 |
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2021 Journal Article In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafishXiong, Zherui, Lo, Harriet P., McMahon, Kerrie-Ann, Martel, Nick, Jones, Alun, Hill, Michelle M., Parton, Robert G. and Hall, Thomas E. (2021). In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish. eLife, 10 e64631, 1-21. doi: 10.7554/elife.64631 |
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2021 Journal Article Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formationTillu, Vikas A., Rae, James, Gao, Ya, Ariotti, Nicholas, Floetenmeyer, Matthias, Kovtun, Oleksiy, McMahon, Kerrie-Ann, Chaudhary, Natasha, Parton, Robert G. and Collins, Brett M. (2021). Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation. Nature Communications, 12 (1) 931, 931. doi: 10.1038/s41467-021-21035-4 |
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2021 Journal Article Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusionDuszyc, Kinga, Gomez, Guillermo A., Lagendijk, Anne K., Yau, Mei-Kwan, Nanavati, Bageshri Naimish, Gliddon, Briony L., Hall, Thomas E., Verma, Suzie, Hogan, Benjamin M., Pitson, Stuart M., Fairlie, David P., Parton, Robert G. and Yap, Alpha S. (2021). Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion. Current Biology, 31 (6), 1326-1336.e5. doi: 10.1016/j.cub.2021.01.003 |
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2021 Journal Article Caveolin-1 influences epithelial collective cell migration via FMNL2 forminKatsuno-Kambe, Hiroko, Parton, Robert G, Yap, Alpha S and Teo, Jessica L (2021). Caveolin-1 influences epithelial collective cell migration via FMNL2 formin. Biology of the Cell, 113 (2), 107-117. doi: 10.1111/boc.202000116 |
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2021 Journal Article Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolaeZhou, Yong, Ariotti, Nicholas, Rae, James, Liang, Hong, Tillu, Vikas, Tee, Shern, Bastiani, Michele, Bademosi, Adekunle T., Collins, Brett M., Meunier, Frederic A., Hancock, John F. and Parton, Robert G. (2021). Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae. Journal of Cell Biology, 220 (3) e202005138. doi: 10.1083/jcb.202005138 |
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2021 Journal Article Formation of retromer transport carriers is disrupted by the Parkinson disease‐linked Vps35 D620N variantCui, Yi, Yang, Zhe, Flores‐Rodriguez, Neftali, Follett, Jordan, Ariotti, Nicholas, Wall, Adam A., Parton, Robert G. and Teasdale, Rohan D. (2021). Formation of retromer transport carriers is disrupted by the Parkinson disease‐linked Vps35 D620N variant. Traffic, 22 (4) tra.12779, 123-136. doi: 10.1111/tra.12779 |
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2021 Journal Article Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasiaYeo, Abrey J., Kok, Chong L., Gatei, Magtouf, Zou, Dongxiu, Stewart, Romal, Withey, Sarah, Wolvetang, Ernst, Parton, Robert G., Brown, Adam D., Kastan, Michael B., Coman, David and Lavin, Martin F. (2021). Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia. iScience, 24 (1) 101972, 101972. doi: 10.1016/j.isci.2020.101972 |
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2021 Journal Article Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recyclingLonic, Ana, Gehling, Freya, Belle, Leila, Li, Xiaochun, Schieber, Nicole L., Nguyen, Elizabeth V., Goodall, Gregory J., Parton, Robert G., Daly, Roger J. and Khew-Goodall, Yeesim (2021). Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling. Journal of Cell Biology, 220 (2) e201902073. doi: 10.1083/jcb.201902073 |
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2021 Journal Article Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent mannerAbbasi, Mojdeh, Gupta, Vivek K., Chitranshi, Nitin, Gupta, Veer, Ranjbaran, Reza, Rajput, Rashi, Pushpitha, Kanishka, Devaraj, K. B., You, Yuyi, Salekdeh, Ghasem Hosseini, Parton, Robert G., Mirzaei, Mehdi and Graham, Stuart L. (2021). Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent manner. Theranostics, 11 (13), 6154-6172. doi: 10.7150/thno.55472 |
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2021 Journal Article ContactJ: lipid droplets-mitochondria contacts characterization through fluorescence microscopy and image analysisMartín, Gemma, Bosch, Marta, Coll, Elisenda, Parton, Robert G., Pol, Albert and Calvo, Maria (2021). ContactJ: lipid droplets-mitochondria contacts characterization through fluorescence microscopy and image analysis. F1000Research, 10 263. doi: 10.12688/f1000research.51900.1 |
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2020 Journal Article Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodiesGormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117 |
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2020 Journal Article A new direction for TrafficMarks, Michael S., Parton, Robert G., Schroer, Trina A., Tooze, Sharon A., Brodsky, Frances M., Marsh, Mark, Schmid, Sandra L., Griffiths, Gillian M., Stevens, Tom H. and van Meer, Gerrit (2020). A new direction for Traffic. Traffic, 21 (12), 724-724. doi: 10.1111/tra.12763 |
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2020 Journal Article Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusionTeo, Jessica L, Tomatis, Vanesa M, Coburn, Luke, Lagendijk, Anne K, Schouwenaar, Irin-Maya, Budnar, Srikanth, Hall, Thomas E, Verma, Suzie, McLachlan, Robert W, Hogan, Benjamin M, Parton, Robert G, Yap, Alpha S and Gomez, Guillermo A (2020). Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion. Molecular Biology of the Cell, 31 (23), 2495-2629. doi: 10.1091/mbc.E20-01-0084 |
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2020 Journal Article Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defenseBosch, Marta, Sánchez-Álvarez, Miguel, Fajardo, Alba, Kapetanovic, Ronan, Steiner, Bernhard, Dutra, Filipe, Moreira, Luciana, López, Juan Antonio, Campo, Rocío, Marí, Montserrat, Morales-Paytuví, Frederic, Tort, Olivia, Gubern, Albert, Templin, Rachel M., Curson, James E. B., Martel, Nick, Català, Cristina, Lozano, Francisco, Tebar, Francesc, Enrich, Carlos, Vázquez, Jesús, Del Pozo, Miguel A., Sweet, Matthew J., Bozza, Patricia T., Gross, Steven P., Parton, Robert G. and Pol, Albert (2020). Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense. Science, 370 (6514) 8085, 309-+. doi: 10.1126/science.aay8085 |
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2020 Journal Article An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cellsAriotti, Nicholas, Wu, Yeping, Okano, Satomi, Gambin, Yann, Follett, Jordan, Rae, James, Ferguson, Charles, Teasdale, Rohan D., Alexandrov, Kirill, Meunier, Frederic A., Hill, Michelle M. and Parton, Robert G. (2020). An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells. Autophagy, 17 (9), 1-17. doi: 10.1080/15548627.2020.1820787 |
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2020 Journal Article Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasoundPandit, Rucha, Koh, Wee Kiat, Sullivan, Robert K.P., Palliyaguru, Tishila, Parton, Robert G. and Götz, Jürgen (2020). Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasound. Journal of Controlled Release, 327, 667-675. doi: 10.1016/j.jconrel.2020.09.015 |
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2020 Journal Article Caveolae: Formation, dynamics, and functionParton, Robert G., McMahon, Kerrie-Ann and Wu, Yeping (2020). Caveolae: Formation, dynamics, and function. Current Opinion in Cell Biology, 65, 8-16. doi: 10.1016/j.ceb.2020.02.001 |
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2020 Journal Article In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formationHall, Thomas E., Martel, Nick, Ariotti, Nicholas, Xiong, Zherui, Lo, Harriet P., Ferguson, Charles, Rae, James, Lim, Ye-Wheen and Parton, Robert G. (2020). In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation. Nature Communications, 11 (1) 3711, 3711. doi: 10.1038/s41467-020-17486-w |
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2020 Journal Article Caveolin-1 ablation imparts partial protection against inner retinal injury in experimental glaucoma and reduces apoptotic activationAbbasi, Mojdeh, Gupta, Vivek K., Chitranshi, Nitin, Gupta, Veer B., Mirzaei, Mehdi, Dheer, Yogita, Garthwaite, Linda, Zaw, Thiri, Parton, Robert G., You, Yuyi and Graham, Stuart L. (2020). Caveolin-1 ablation imparts partial protection against inner retinal injury in experimental glaucoma and reduces apoptotic activation. Molecular Neurobiology, 57 (9), 3759-3784. doi: 10.1007/s12035-020-01948-9 |
