2021 Journal Article Formation of retromer transport carriers is disrupted by the Parkinson disease‐linked Vps35 D620N variantCui, Yi, Yang, Zhe, Flores‐Rodriguez, Neftali, Follett, Jordan, Ariotti, Nicholas, Wall, Adam A., Parton, Robert G. and Teasdale, Rohan D. (2021). Formation of retromer transport carriers is disrupted by the Parkinson disease‐linked Vps35 D620N variant. Traffic, 22 (4) tra.12779, 123-136. doi: 10.1111/tra.12779 |
2021 Journal Article Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasiaYeo, Abrey J., Kok, Chong L., Gatei, Magtouf, Zou, Dongxiu, Stewart, Romal, Withey, Sarah, Wolvetang, Ernst, Parton, Robert G., Brown, Adam D., Kastan, Michael B., Coman, David and Lavin, Martin F. (2021). Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia. iScience, 24 (1) 101972, 101972. doi: 10.1016/j.isci.2020.101972 |
2021 Journal Article Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recyclingLonic, Ana, Gehling, Freya, Belle, Leila, Li, Xiaochun, Schieber, Nicole L., Nguyen, Elizabeth V., Goodall, Gregory J., Parton, Robert G., Daly, Roger J. and Khew-Goodall, Yeesim (2021). Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling. Journal of Cell Biology, 220 (2) e201902073. doi: 10.1083/jcb.201902073 |
2021 Journal Article Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent mannerAbbasi, Mojdeh, Gupta, Vivek K., Chitranshi, Nitin, Gupta, Veer, Ranjbaran, Reza, Rajput, Rashi, Pushpitha, Kanishka, Devaraj, K. B., You, Yuyi, Salekdeh, Ghasem Hosseini, Parton, Robert G., Mirzaei, Mehdi and Graham, Stuart L. (2021). Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent manner. Theranostics, 11 (13), 6154-6172. doi: 10.7150/thno.55472 |
2021 Journal Article ContactJ: lipid droplets-mitochondria contacts characterization through fluorescence microscopy and image analysisMartín, Gemma, Bosch, Marta, Coll, Elisenda, Parton, Robert G., Pol, Albert and Calvo, Maria (2021). ContactJ: lipid droplets-mitochondria contacts characterization through fluorescence microscopy and image analysis. F1000Research, 10 263. doi: 10.12688/f1000research.51900.1 |
2020 Journal Article A new direction for TrafficMarks, Michael S., Parton, Robert G., Schroer, Trina A., Tooze, Sharon A., Brodsky, Frances M., Marsh, Mark, Schmid, Sandra L., Griffiths, Gillian M., Stevens, Tom H. and van Meer, Gerrit (2020). A new direction for Traffic. Traffic, 21 (12), 724-724. doi: 10.1111/tra.12763 |
2020 Journal Article Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodiesGormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117 |
2020 Journal Article Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusionTeo, Jessica L, Tomatis, Vanesa M, Coburn, Luke, Lagendijk, Anne K, Schouwenaar, Irin-Maya, Budnar, Srikanth, Hall, Thomas E, Verma, Suzie, McLachlan, Robert W, Hogan, Benjamin M, Parton, Robert G, Yap, Alpha S and Gomez, Guillermo A (2020). Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion. Molecular Biology of the Cell, 31 (23), 2495-2629. doi: 10.1091/mbc.E20-01-0084 |
2020 Journal Article Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defenseBosch, Marta, Sánchez-Álvarez, Miguel, Fajardo, Alba, Kapetanovic, Ronan, Steiner, Bernhard, Dutra, Filipe, Moreira, Luciana, López, Juan Antonio, Campo, Rocío, Marí, Montserrat, Morales-Paytuví, Frederic, Tort, Olivia, Gubern, Albert, Templin, Rachel M., Curson, James E. B., Martel, Nick, Català, Cristina, Lozano, Francisco, Tebar, Francesc, Enrich, Carlos, Vázquez, Jesús, Del Pozo, Miguel A., Sweet, Matthew J., Bozza, Patricia T., Gross, Steven P., Parton, Robert G. and Pol, Albert (2020). Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense. Science, 370 (6514) 8085, 309-+. doi: 10.1126/science.aay8085 |
2020 Other Outputs Nanoscape, a data-driven 3D real-time interactive virtual cell environmentKadir, Shereen R., Lilja, Andrew, Gunn, Nick, Strong, Campbell, Hughes, Rowan T., Bailey, Benjamin J., Rae, James, Parton, Robert G. and McGhee, John (2020). Nanoscape, a data-driven 3D real-time interactive virtual cell environment. doi: 10.1101/2020.10.15.340778 |
2020 Journal Article An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cellsAriotti, Nicholas, Wu, Yeping, Okano, Satomi, Gambin, Yann, Follett, Jordan, Rae, James, Ferguson, Charles, Teasdale, Rohan D., Alexandrov, Kirill, Meunier, Frederic A., Hill, Michelle M. and Parton, Robert G. (2020). An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells. Autophagy, 17 (9), 1-17. doi: 10.1080/15548627.2020.1820787 |
2020 Journal Article Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasoundPandit, Rucha, Koh, Wee Kiat, Sullivan, Robert K.P., Palliyaguru, Tishila, Parton, Robert G. and Götz, Jürgen (2020). Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasound. Journal of Controlled Release, 327, 667-675. doi: 10.1016/j.jconrel.2020.09.015 |
2020 Journal Article Caveolae: Formation, dynamics, and functionParton, Robert G., McMahon, Kerrie-Ann and Wu, Yeping (2020). Caveolae: Formation, dynamics, and function. Current Opinion in Cell Biology, 65, 8-16. doi: 10.1016/j.ceb.2020.02.001 |
2020 Journal Article In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formationHall, Thomas E., Martel, Nick, Ariotti, Nicholas, Xiong, Zherui, Lo, Harriet P., Ferguson, Charles, Rae, James, Lim, Ye-Wheen and Parton, Robert G. (2020). In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation. Nature Communications, 11 (1) 3711, 3711. doi: 10.1038/s41467-020-17486-w |
2020 Journal Article Caveolin-1 ablation imparts partial protection against inner retinal injury in experimental glaucoma and reduces apoptotic activationAbbasi, Mojdeh, Gupta, Vivek K., Chitranshi, Nitin, Gupta, Veer B., Mirzaei, Mehdi, Dheer, Yogita, Garthwaite, Linda, Zaw, Thiri, Parton, Robert G., You, Yuyi and Graham, Stuart L. (2020). Caveolin-1 ablation imparts partial protection against inner retinal injury in experimental glaucoma and reduces apoptotic activation. Molecular Neurobiology, 57 (9), 3759-3784. doi: 10.1007/s12035-020-01948-9 |
2020 Journal Article Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coliStocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r |
2020 Journal Article Novel contact sites between lipid droplets, early endosomes, and the endoplasmic reticulumParton, Robert G., Bosch, Marta, Steiner, Bernhard and Pol, Albert (2020). Novel contact sites between lipid droplets, early endosomes, and the endoplasmic reticulum. Journal of Lipid Research, 61 (11), jlr.ILR120000876-1364. doi: 10.1194/jlr.ilr120000876 |
2020 Journal Article Non-caveolar caveolins - duties outside the cavesPol, Albert, Morales-Paytuví, Frederic, Bosch, Marta and Parton, Robert G. (2020). Non-caveolar caveolins - duties outside the caves. Journal of Cell Science, 133 (9) jcs241562, jcs241562. doi: 10.1242/jcs.241562 |
2020 Journal Article Growth hormone stops excessive inflammation after partial hepatectomy allowing liver regeneration and survival via induction of H2-Bl/HLA-GIshikawa, Mayumi, Brooks, Andrew J., Fernández-Rojo, Manuel A., Medina, Johan, Chhabra, Yash, Minami, Shiro, Tunny, Kathryn A., Parton, Robert G., Vivian, Julian P., Rossjohn, Jamie, Chikani, Viral, Ramm, Grant A., Ho, Ken K. Y. and Waters, Michael J. (2020). Growth hormone stops excessive inflammation after partial hepatectomy allowing liver regeneration and survival via induction of H2-Bl/HLA-G. Hepatology, 73 (2) hep.31297, 759-775. doi: 10.1002/hep.31297 |
2020 Journal Article Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacityBywater, Megan J., Burkhart, Deborah L., Straube, Jasmin, Sabò, Arianna, Pendino, Vera, Hudson, James E., Quaife-Ryan, Gregory A., Porrello, Enzo R., Rae, James, Parton, Robert G., Kress, Theresia R., Amati, Bruno, Littlewood, Trevor D., Evan, Gerard I. and Wilson, Catherine H. (2020). Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nature Communications, 11 (1) 1827, 1827. doi: 10.1038/s41467-020-15552-x |