Overview
Background
Dr Mostafa Kamal Masud is a CCQ Next Generation Cancer Research Fellow at the Australian Institute for Bioengineering & Nanotechnology (AIBN), the University of Queensland (UQ). In 2020, he received his PhD in Medical Biotechnology Diagnostics and Nanobiotechnology from AIBN, UQ. He received his MS and B.Sc. (Hons.) in Chemistry from Shahjalal University of Science and Technology (SUST), Sylhet-3114, Bangladesh. After completing his PhD, he was awarded a prestigious JSPS Postdoctoral Fellowship (success rate >10%) from Japan and served as a Postdoctoral Fellow at Japan's National Institute for Materials Science (NIMS).He recently been awarded a highly prestigious ARC DECRA fellowship for the period 2024-2026 and a QLD Cancer Council fellowship for the period 2024–2028. His research focuses on the development of novel nanostructures and nanodiagnostic technologies to address critical issues in medical diagnosis. As an early career researcher, he has an excellent track record with more than 50 peer-reviewed publications in prestigious and high-impact journals in the area that achieve <2400 citations with an h-index of 26 (Scholar google link: https://bit.ly/2Vtv67l). He has developed new classes of superparamagnetic nanostructures and fabricated novel biosensors for the detection of disease-specific biomolecular targets e.g., for miRNA, DNA, exosome and protein biomarker detection that have proven to be easy and effective, allowing for rapid diagnosis with minimal equipment. He made a major contribution to nanotechnology integrated-analytical and diagnostic fields by providing analytical and technological input as well as developing key collaborations with clinicians and biologists for translational research. His strategy is to create nano-architecture point-of-care diagnostic technology for early diagnosis of cancer that could hopefully lead to a healthy and happier life for humans.
Availability
- Dr Mostafa Kamal Masud is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Chemistry, unknown
- Masters (Research) of Inorganic Chemistry, unknown
- Doctor of Philosophy, The University of Queensland
Research interests
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Nanoarchitectonics
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Medical Diagnostics
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Biosensor
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Nanobiotechnology
Research impacts
Dr Masud pioneered the synthesis of new classes of superparamagnetic nanostructures specific to targeting biomarkers or capturing antibodies. His synthesized nanostructures perform rapid isolation based on simple magnetism and exhibit intrinsic peroxidase activities, substantially replacing the expensive natural enzyme (HRP) in immunoassays and strip-based sensing. These nanostructures are utilized in fabricating novel biosensors for detecting disease-specific biomarkers such as microRNA, autoantibodies, and extracellular vesicles (exosomes). This research has advanced the field from polymer- or centrifuge-based isolation and enzyme-based detection to more efficient and straightforward synthesis of target-specific mesoporous nanostructures, magnetic isolation, and single-step detection.
He also led the development of highly sensitive mesoporous gold (and alloy) transduction surfaces, simplifying the process from complex to single-step. His research characterized biomarkers (exosomal miRNAs), transduction surface interactions, bindings, and sensitive signal generation. He also led the translation of such mesoporous systems into wearable and flexible substrates, demonstrating high neural activity in a mouse model, thereby advancing the field of wearable diagnostics. To translate his research into clinical settings, he has initiated collaborations with clinicians, engineers, and IoT specialists
Works
Search Professor Mostafa Kamal Masud’s works on UQ eSpace
Featured
2023
Journal Article
Au-loaded superparamagnetic mesoporous bimetallic CoFeB nanovehicles for sensitive autoantibody detection
Kang, Yunqing, Masud, Mostafa Kamal, Guo, Yanna, Zhao, Yingji, Nishat, Zakia Sultana, Zhao, Jingjing, Jiang, Bo, Sugahara, Yoshiyuki, Pejovic, Tanja, Morgan, Terry, Hossain, Md Shahriar A., Li, Hexing, Salomon, Carlos, Asahi, Toru and Yamauchi, Yusuke (2023). Au-loaded superparamagnetic mesoporous bimetallic CoFeB nanovehicles for sensitive autoantibody detection. ACS Nano, 17 (4), 3346-3357. doi: 10.1021/acsnano.2c07694
Featured
2022
Journal Article
Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing
Nishat, Zakia Sultana, Hossain, Tanvir, Islam, Md. Nazmul, Phan, Hoang‐Phuong, Wahab, Md A., Moni, Mohammad Ali, Salomon, Carlos, Amin, Mohammed A., Sina, Abu Ali Ibn, Hossain, Md Shahriar A., Kaneti, Yusuf Valentino, Yamauchi, Yusuke and Masud, Mostafa Kamal (2022). Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing. Small, 18 (26) 2107571, 2107571. doi: 10.1002/smll.202107571
Featured
2020
Journal Article
Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level
Masud, Mostafa Kamal, Na, Jongbeom, Lin, Tzu-En, Malgras, Victor, Preet, Anant, Ibn Sina, Abu Ali, Wood, Kathleen, Billah, Mutasim, Kim, Jeonghun, You, Jungmok, Kani, Kenya, Whitten, Andrew E., Salomon, Carlos, Nguyen, Nam-Trung, Shiddiky, Muhammad J.A., Trau, Matt, Hossain, MdShahriar A. and Yamauchi, Yusuke (2020). Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level. Biosensors and Bioelectronics, 168 112429, 1-9. doi: 10.1016/j.bios.2020.112429
Featured
2019
Journal Article
Superparamagnetic nanoarchitectures for disease-specific biomarker detection
Masud, Mostafa Kamal, Na, Jongbeom, Younus, Muhammad, Hossain, Md. Shahriar A., Bando, Yoshio, Shiddiky, Muhammad J. A. and Yamauchi, Yusuke (2019). Superparamagnetic nanoarchitectures for disease-specific biomarker detection. Chemical Society Reviews, 48 (24), 5717-5751. doi: 10.1039/c9cs00174c
Featured
2017
Journal Article
Gold-loaded nanoporous ferric oxide nanocubes with peroxidase-mimicking activity for electrocatalytic and colorimetric Detection of autoantibody
Masud, Mostafa Kamal, Yadav, Sharda, Islam, Md. Nazmul, Nguyen, Nam-Trung, Salomon, Carlos, Kline, Richard, Alamri, Hatem R., Alothman, Zeid A., Yamauchi, Yusuke, Hossain, Md. Shahriar A. and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous ferric oxide nanocubes with peroxidase-mimicking activity for electrocatalytic and colorimetric Detection of autoantibody. Analytical Chemistry, 89 (20), 11005-11013. doi: 10.1021/acs.analchem.7b02880
Featured
2017
Journal Article
Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA
Masud, Mostafa Kamal, Islam, Md. Nazmul, Haque, Md. Hakimul, Tanaka, Shunsuke, Gopalan, Vinod, Alici, Gursel, Nguyen, Nam-Trung, Lam, Alfred K., Hossain, Md. Shahriar A., Yamauchi, Yusuke and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA. Chemical Communications, 53 (58), 8231-8234. doi: 10.1039/c7cc04789d
2024
Journal Article
Bimetallic Metal-Organic Framework-Derived porous One-Dimensional carbon materials for electrochemical sensing of dopamine
Chowdhury, Silvia, Nugraha, Asep Sugih, O'May, Riley, Wang, Xiaohan, Cheng, Ping, Xin, Ruijing, Osman, Sameh M., Hossain, Md Shahriar, Yamauchi, Yusuke, Masud, Mostafa Kamal and Kaneti, Yusuf Valentino (2024). Bimetallic Metal-Organic Framework-Derived porous One-Dimensional carbon materials for electrochemical sensing of dopamine. Chemical Engineering Journal, 492 152124, 1-11. doi: 10.1016/j.cej.2024.152124
2024
Journal Article
A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue
Shanmugasundaram, Karthik B., Ahmed, Emtiaz, Miao, Xinzhe, Kulasinghe, Arutha, Fletcher, James A., Monkman, James, Mainwaring, Paul, Masud, Mostafa Kamal, Park, Hyeongyu, Hossain, Md Shahriar A., Yamauchi, Yusuke, Sina, Abu A. I., O’Byrne, Kenneth, Wuethrich, Alain and Trau, Matt (2024). A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue. ACS Sensors, 9 (6), 3009-3016. doi: 10.1021/acssensors.4c00192
2024
Journal Article
Giant piezoresponse in nanoporous (Ba,Ca)(Ti,Zr)O<sub>3</sub> thin film
Billah, Motasim, Terasawa, Yukana, Masud, Mostafa Kamal, Asahi, Toru, Hegazy, Mohamed Barakat Zakaria, Nagata, Takahiro, Chikyow, Toyohiro, Uesugi, Fumihiko, Hossain, Md. Shahriar A. and Yamauchi, Yusuke (2024). Giant piezoresponse in nanoporous (Ba,Ca)(Ti,Zr)O3 thin film. Chemical Science, 15 (24), 9147-9154. doi: 10.1039/d3sc06712b
2024
Journal Article
Mesoporous gold: substrate-dependent growth dynamics, strain accumulation, and electrocatalytic activity for biosensing
Park, Hyeongyu, Masud, Mostafa Kamal, Ashok, Aditya, Kim, Minjun, Wahab, Md Abdul, Zhou, Jun, Terasawa, Yukana, Salomon Gallo, Carlos, Nguyen, Nam-Trung, Hossain, Md Shahriar A., Yamauchi, Yusuke and Kaneti, Yusuf Valentino (2024). Mesoporous gold: substrate-dependent growth dynamics, strain accumulation, and electrocatalytic activity for biosensing. Small, 20 (35) e2311645, e2311645. doi: 10.1002/smll.202311645
2024
Journal Article
A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells
Ahmed, Emtiaz, Masud, Mostafa Kamal, Komatineni, Prathyusha, Dey, Shuvashis, Lobb, Richard, Hossain, Md Shahriar A., Möller, Andreas, Yamauchi, Yusuke, Sina, Abu Ali Ibn and Trau, Matt (2024). A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells. Biosensors and Bioelectronics, 249 115984, 1-9. doi: 10.1016/j.bios.2023.115984
2024
Journal Article
Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis
Lin, Xuan, Vasanth, Arya, Ashok, Aditya, Phan, Hoang-Phuong, Koo, Kevin M., Amin, Mohammed A., Kaneti, Yusuf Valentino, Salomon, Carlos, Hossain, Md Shahriar A., Yamauchi, Yusuke and Masud, Mostafa Kamal (2024). Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis. Nano Materials Science. doi: 10.1016/j.nanoms.2024.01.010
2024
Journal Article
Plasmonic Mesoporous Gold-Based SERS-Microfluidic Platform for the Detection of Infectious Disease
Masud, Mostafa Kamal, Natsuhara, Daigo, Dai, Yuchen, Bashir, Javeria, Nugraha, Asep Sugih, Alshehri, Saad M., Bando, Yoshio, Hossain, Md. Shahriar A., Kaneti, Yusuf Valentino, Shibata, Takayuki and Yamauchi, Yusuke (2024). Plasmonic Mesoporous Gold-Based SERS-Microfluidic Platform for the Detection of Infectious Disease. Journal of Materials Chemistry C. doi: 10.1039/d4tc01638f
2023
Journal Article
Confronting anxiety in the era of COVID-19: investigating the prevalence and impact on daily life in Bangladesh
Islam, Md Rashadul, Sony, Sabrina Amita, Imran, Md Ashik, Disha, Sadia Sinty, Murshed, Mortuja Kamal, Talukdar, Sutapa, Pramanik, Shishir Kanti, Masud, Mostafa Kamal, Kalam Azad, Muhammad Abdul and Al Shoeb, Mohammad Abdullah (2023). Confronting anxiety in the era of COVID-19: investigating the prevalence and impact on daily life in Bangladesh. Bioresearch Communications, 10 (1), 1378-1385. doi: 10.3329/brc.v10i1.70646
2023
Conference Publication
Extracellular Small Vesicle Phosphorylated PD-L1 Liquid Biopsy Levels Correlate with Tumour Proportion Score (TPS) in NSCLC
O'Byrne, K., Shanmugasundaram, K.B., Ahmed, E., Kulasinghe, A., Monkman, J., Fletcher, J.A., Mainwaring, P.N., Masud, M.K., Park, H., Hossain, M.S.A., Yamauchi, Y., Sina, A.A.I., Wuethrich, A. and Trau, M. (2023). Extracellular Small Vesicle Phosphorylated PD-L1 Liquid Biopsy Levels Correlate with Tumour Proportion Score (TPS) in NSCLC. 2023 World Conference on Lung Cancer, Singapore, 9-12 September 2023. New York, NY United States: Elsevier. doi: 10.1016/j.jtho.2023.09.432
2023
Journal Article
Mesoporous Metastable CuTe<sub>2</sub> Semiconductor
Ashok, Aditya, Vasanth, Arya, Nagaura, Tomota, Setter, Caitlin, Clegg, Jack Kay, Fink, Alexander, Masud, Mostafa Kamal, Hossain, Md Shahriar, Hamada, Takashi, Eguchi, Miharu, Phan, Hoang-Phuong and Yamauchi, Yusuke (2023). Mesoporous Metastable CuTe2 Semiconductor. Journal of the American Chemical Society, 145 (43), 23461-23469. doi: 10.1021/jacs.3c05846
2023
Journal Article
Flexible nanoarchitectonics for biosensing and physiological monitoring applications
Ashok, Aditya, Nguyen, Tuan-Khoa, Barton, Matthew, Leitch, Michael, Masud, Mostafa Kamal, Park, Hyeongyu, Truong, Thanh-An, Kaneti, Yusuf Valentino, Ta, Hang Thu, Li, Xiaopeng, Liang, Kang, Do, Thanh Nho, Wang, Chun-Hui, Nguyen, Nam-Trung, Yamauchi, Yusuke and Phan, Hoang-Phuong (2023). Flexible nanoarchitectonics for biosensing and physiological monitoring applications. Small, 19 (9) 2204946, 1-11. doi: 10.1002/smll.202204946
2023
Journal Article
Flexible nanoarchitectonics for biosensing and physiological monitoring applications (Small 9/2023)
Ashok, Aditya, Nguyen, Tuan‐Khoa, Barton, Matthew, Leitch, Michael, Masud, Mostafa Kamal, Park, Hyeongyu, Truong, Thanh‐An, Kaneti, Yusuf Valentino, Ta, Hang Thu, Li, Xiaopeng, Liang, Kang, Do, Thanh Nho, Wang, Chun‐Hui, Nguyen, Nam‐Trung, Yamauchi, Yusuke and Phan, Hoang‐Phuong (2023). Flexible nanoarchitectonics for biosensing and physiological monitoring applications (Small 9/2023). Small, 19 (9) 2370053. doi: 10.1002/smll.202370053
2023
Book Chapter
Electrochemical biosensor for cancer biomarkers detection
Arifuzzaman, Md, Kamal Masud, Mostafa, Ahmed, Asif, Morsaline Billah, Md and Nazmul Islam, Md (2023). Electrochemical biosensor for cancer biomarkers detection. Current cancer biomarkers. (pp. 349-371) Sharjah, U.A.E: Bentham Science Publishers. doi: 10.2174/9789815079364123010017
2023
Journal Article
Electrochemical nitrogen fixation in metal-N2 batteries: A paradigm for simultaneous NH3 synthesis and energy generation
Islam, Jahidul, Shareef, Mahmud, Zabed, Hossain M., Qi, Xianghui, Chowdhury, Faisal Islam, Das, Jagotamoy, Uddin, Jamal, Kaneti, Yusuf Valentino, Khandaker, Mayeen Uddin, Idris, Abubakr M., Ullah, Md. Habib and Masud, Mostafa Kamal (2023). Electrochemical nitrogen fixation in metal-N2 batteries: A paradigm for simultaneous NH3 synthesis and energy generation. Energy Storage Materials, 54, 98-119. doi: 10.1016/j.ensm.2022.10.007
Supervision
Availability
- Dr Mostafa Kamal Masud is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Magneto Plasmonic Mesoporous nanostructures for the profiling of clinically relevant biomarkers
Associate Advisor
Other advisors: Professor Yusuke Yamauchi, Dr Valentino Kaneti, Associate Professor MD Shahriar Hossain
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Doctor Philosophy
Nanoarchitectured Multifunctional Porous Superparamagnetic Nanoparticles
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Associate Professor MD Shahriar Hossain, Dr Valentino Kaneti, Professor Yusuke Yamauchi
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Doctor Philosophy
Nanoarchitectured Multifunctional Porous Superparamagnetic Nanoparticles
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Associate Professor MD Shahriar Hossain, Dr Valentino Kaneti, Professor Yusuke Yamauchi
Completed supervision
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2024
Doctor Philosophy
Nanoarchitectured Mesoporous Gold-Alloy for microRNA Sensing
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Professor Yusuke Yamauchi, Dr Valentino Kaneti, Associate Professor MD Shahriar Hossain
Media
Enquiries
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