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Dr Mostafa Kamal Masud
Dr

Mostafa Kamal Masud

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Overview

Background

Dr Mostafa Kamal Masud is a CCQ Next Generation Cancer Research Fellow at the Australian Institute for Bioengineering & Nanotechnology (AIBN), the University of Queensland (UQ). In 2020, he received his PhD in Medical Biotechnology Diagnostics and Nanobiotechnology from AIBN, UQ. He received his MS and B.Sc. (Hons.) in Chemistry from Shahjalal University of Science and Technology (SUST), Sylhet-3114, Bangladesh. After completing his PhD, he was awarded a prestigious JSPS Postdoctoral Fellowship (success rate >10%) from Japan and served as a Postdoctoral Fellow at Japan's National Institute for Materials Science (NIMS).He recently been awarded a highly prestigious ARC DECRA fellowship for the period 2024-2026 and a QLD Cancer Council fellowship for the period 2024–2028. His research focuses on the development of novel nanostructures and nanodiagnostic technologies to address critical issues in medical diagnosis. As an early career researcher, he has an excellent track record with more than 50 peer-reviewed publications in prestigious and high-impact journals in the area that achieve <2400 citations with an h-index of 26 (Scholar google link: https://bit.ly/2Vtv67l). He has developed new classes of superparamagnetic nanostructures and fabricated novel biosensors for the detection of disease-specific biomolecular targets e.g., for miRNA, DNA, exosome and protein biomarker detection that have proven to be easy and effective, allowing for rapid diagnosis with minimal equipment. He made a major contribution to nanotechnology integrated-analytical and diagnostic fields by providing analytical and technological input as well as developing key collaborations with clinicians and biologists for translational research. His strategy is to create nano-architecture point-of-care diagnostic technology for early diagnosis of cancer that could hopefully lead to a healthy and happier life for humans.

Availability

Dr Mostafa Kamal Masud is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours) of Chemistry, unknown
  • Masters (Research) of Inorganic Chemistry, unknown
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Nanoarchitectonics

  • Medical Diagnostics

  • Biosensor

  • Nanobiotechnology

Research impacts

Dr Masud pioneered the synthesis of new classes of superparamagnetic nanostructures specific to targeting biomarkers or capturing antibodies. His synthesized nanostructures perform rapid isolation based on simple magnetism and exhibit intrinsic peroxidase activities, substantially replacing the expensive natural enzyme (HRP) in immunoassays and strip-based sensing. These nanostructures are utilized in fabricating novel biosensors for detecting disease-specific biomarkers such as microRNA, autoantibodies, and extracellular vesicles (exosomes). This research has advanced the field from polymer- or centrifuge-based isolation and enzyme-based detection to more efficient and straightforward synthesis of target-specific mesoporous nanostructures, magnetic isolation, and single-step detection.

He also led the development of highly sensitive mesoporous gold (and alloy) transduction surfaces, simplifying the process from complex to single-step. His research characterized biomarkers (exosomal miRNAs), transduction surface interactions, bindings, and sensitive signal generation. He also led the translation of such mesoporous systems into wearable and flexible substrates, demonstrating high neural activity in a mouse model, thereby advancing the field of wearable diagnostics. To translate his research into clinical settings, he has initiated collaborations with clinicians, engineers, and IoT specialists

Works

Search Professor Mostafa Kamal Masud’s works on UQ eSpace

57 works between 2016 and 2024

1 - 20 of 57 works

Featured

2023

Journal Article

Au-loaded superparamagnetic mesoporous bimetallic CoFeB nanovehicles for sensitive autoantibody detection

Kang, Yunqing, Masud, Mostafa Kamal, Guo, Yanna, Zhao, Yingji, Nishat, Zakia Sultana, Zhao, Jingjing, Jiang, Bo, Sugahara, Yoshiyuki, Pejovic, Tanja, Morgan, Terry, Hossain, Md Shahriar A., Li, Hexing, Salomon, Carlos, Asahi, Toru and Yamauchi, Yusuke (2023). Au-loaded superparamagnetic mesoporous bimetallic CoFeB nanovehicles for sensitive autoantibody detection. ACS Nano, 17 (4), 3346-3357. doi: 10.1021/acsnano.2c07694

Au-loaded superparamagnetic mesoporous bimetallic CoFeB nanovehicles for sensitive autoantibody detection

Featured

2022

Journal Article

Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing

Nishat, Zakia Sultana, Hossain, Tanvir, Islam, Md. Nazmul, Phan, Hoang‐Phuong, Wahab, Md A., Moni, Mohammad Ali, Salomon, Carlos, Amin, Mohammed A., Sina, Abu Ali Ibn, Hossain, Md Shahriar A., Kaneti, Yusuf Valentino, Yamauchi, Yusuke and Masud, Mostafa Kamal (2022). Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing. Small, 18 (26) 2107571, 2107571. doi: 10.1002/smll.202107571

Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing

Featured

2020

Journal Article

Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level

Masud, Mostafa Kamal, Na, Jongbeom, Lin, Tzu-En, Malgras, Victor, Preet, Anant, Ibn Sina, Abu Ali, Wood, Kathleen, Billah, Mutasim, Kim, Jeonghun, You, Jungmok, Kani, Kenya, Whitten, Andrew E., Salomon, Carlos, Nguyen, Nam-Trung, Shiddiky, Muhammad J.A., Trau, Matt, Hossain, MdShahriar A. and Yamauchi, Yusuke (2020). Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level. Biosensors and Bioelectronics, 168 112429, 1-9. doi: 10.1016/j.bios.2020.112429

Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level

Featured

2019

Journal Article

Superparamagnetic nanoarchitectures for disease-specific biomarker detection

Masud, Mostafa Kamal, Na, Jongbeom, Younus, Muhammad, Hossain, Md. Shahriar A., Bando, Yoshio, Shiddiky, Muhammad J. A. and Yamauchi, Yusuke (2019). Superparamagnetic nanoarchitectures for disease-specific biomarker detection. Chemical Society Reviews, 48 (24), 5717-5751. doi: 10.1039/c9cs00174c

Superparamagnetic nanoarchitectures for disease-specific biomarker detection

Featured

2017

Journal Article

Gold-loaded nanoporous ferric oxide nanocubes with peroxidase-mimicking activity for electrocatalytic and colorimetric Detection of autoantibody

Masud, Mostafa Kamal, Yadav, Sharda, Islam, Md. Nazmul, Nguyen, Nam-Trung, Salomon, Carlos, Kline, Richard, Alamri, Hatem R., Alothman, Zeid A., Yamauchi, Yusuke, Hossain, Md. Shahriar A. and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous ferric oxide nanocubes with peroxidase-mimicking activity for electrocatalytic and colorimetric Detection of autoantibody. Analytical Chemistry, 89 (20), 11005-11013. doi: 10.1021/acs.analchem.7b02880

Gold-loaded nanoporous ferric oxide nanocubes with peroxidase-mimicking activity for electrocatalytic and colorimetric Detection of autoantibody

Featured

2017

Journal Article

Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA

Masud, Mostafa Kamal, Islam, Md. Nazmul, Haque, Md. Hakimul, Tanaka, Shunsuke, Gopalan, Vinod, Alici, Gursel, Nguyen, Nam-Trung, Lam, Alfred K., Hossain, Md. Shahriar A., Yamauchi, Yusuke and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA. Chemical Communications, 53 (58), 8231-8234. doi: 10.1039/c7cc04789d

Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA

2024

Journal Article

Bimetallic Metal-Organic Framework-Derived porous One-Dimensional carbon materials for electrochemical sensing of dopamine

Chowdhury, Silvia, Nugraha, Asep Sugih, O'May, Riley, Wang, Xiaohan, Cheng, Ping, Xin, Ruijing, Osman, Sameh M., Hossain, Md Shahriar, Yamauchi, Yusuke, Masud, Mostafa Kamal and Kaneti, Yusuf Valentino (2024). Bimetallic Metal-Organic Framework-Derived porous One-Dimensional carbon materials for electrochemical sensing of dopamine. Chemical Engineering Journal, 492 152124, 1-11. doi: 10.1016/j.cej.2024.152124

Bimetallic Metal-Organic Framework-Derived porous One-Dimensional carbon materials for electrochemical sensing of dopamine

2024

Journal Article

A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue

Shanmugasundaram, Karthik B., Ahmed, Emtiaz, Miao, Xinzhe, Kulasinghe, Arutha, Fletcher, James A., Monkman, James, Mainwaring, Paul, Masud, Mostafa Kamal, Park, Hyeongyu, Hossain, Md Shahriar A., Yamauchi, Yusuke, Sina, Abu A. I., O’Byrne, Kenneth, Wuethrich, Alain and Trau, Matt (2024). A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue. ACS Sensors, 9 (6), 3009-3016. doi: 10.1021/acssensors.4c00192

A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue

2024

Journal Article

Giant piezoresponse in nanoporous (Ba,Ca)(Ti,Zr)O<sub>3</sub> thin film

Billah, Motasim, Terasawa, Yukana, Masud, Mostafa Kamal, Asahi, Toru, Hegazy, Mohamed Barakat Zakaria, Nagata, Takahiro, Chikyow, Toyohiro, Uesugi, Fumihiko, Hossain, Md. Shahriar A. and Yamauchi, Yusuke (2024). Giant piezoresponse in nanoporous (Ba,Ca)(Ti,Zr)O3 thin film. Chemical Science, 15 (24), 9147-9154. doi: 10.1039/d3sc06712b

Giant piezoresponse in nanoporous (Ba,Ca)(Ti,Zr)O<sub>3</sub> thin film

2024

Journal Article

Mesoporous gold: substrate-dependent growth dynamics, strain accumulation, and electrocatalytic activity for biosensing

Park, Hyeongyu, Masud, Mostafa Kamal, Ashok, Aditya, Kim, Minjun, Wahab, Md Abdul, Zhou, Jun, Terasawa, Yukana, Salomon Gallo, Carlos, Nguyen, Nam-Trung, Hossain, Md Shahriar A., Yamauchi, Yusuke and Kaneti, Yusuf Valentino (2024). Mesoporous gold: substrate-dependent growth dynamics, strain accumulation, and electrocatalytic activity for biosensing. Small, 20 (35) e2311645, e2311645. doi: 10.1002/smll.202311645

Mesoporous gold: substrate-dependent growth dynamics, strain accumulation, and electrocatalytic activity for biosensing

2024

Journal Article

A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells

Ahmed, Emtiaz, Masud, Mostafa Kamal, Komatineni, Prathyusha, Dey, Shuvashis, Lobb, Richard, Hossain, Md Shahriar A., Möller, Andreas, Yamauchi, Yusuke, Sina, Abu Ali Ibn and Trau, Matt (2024). A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells. Biosensors and Bioelectronics, 249 115984, 1-9. doi: 10.1016/j.bios.2023.115984

A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells

2024

Journal Article

Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis

Lin, Xuan, Vasanth, Arya, Ashok, Aditya, Phan, Hoang-Phuong, Koo, Kevin M., Amin, Mohammed A., Kaneti, Yusuf Valentino, Salomon, Carlos, Hossain, Md Shahriar A., Yamauchi, Yusuke and Masud, Mostafa Kamal (2024). Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis. Nano Materials Science. doi: 10.1016/j.nanoms.2024.01.010

Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis

2024

Journal Article

Plasmonic Mesoporous Gold-Based SERS-Microfluidic Platform for the Detection of Infectious Disease

Masud, Mostafa Kamal, Natsuhara, Daigo, Dai, Yuchen, Bashir, Javeria, Nugraha, Asep Sugih, Alshehri, Saad M., Bando, Yoshio, Hossain, Md. Shahriar A., Kaneti, Yusuf Valentino, Shibata, Takayuki and Yamauchi, Yusuke (2024). Plasmonic Mesoporous Gold-Based SERS-Microfluidic Platform for the Detection of Infectious Disease. Journal of Materials Chemistry C. doi: 10.1039/d4tc01638f

Plasmonic Mesoporous Gold-Based SERS-Microfluidic Platform for the Detection of Infectious Disease

2023

Journal Article

Confronting anxiety in the era of COVID-19: investigating the prevalence and impact on daily life in Bangladesh

Islam, Md Rashadul, Sony, Sabrina Amita, Imran, Md Ashik, Disha, Sadia Sinty, Murshed, Mortuja Kamal, Talukdar, Sutapa, Pramanik, Shishir Kanti, Masud, Mostafa Kamal, Kalam Azad, Muhammad Abdul and Al Shoeb, Mohammad Abdullah (2023). Confronting anxiety in the era of COVID-19: investigating the prevalence and impact on daily life in Bangladesh. Bioresearch Communications, 10 (1), 1378-1385. doi: 10.3329/brc.v10i1.70646

Confronting anxiety in the era of COVID-19: investigating the prevalence and impact on daily life in Bangladesh

2023

Conference Publication

Extracellular Small Vesicle Phosphorylated PD-L1 Liquid Biopsy Levels Correlate with Tumour Proportion Score (TPS) in NSCLC

O'Byrne, K., Shanmugasundaram, K.B., Ahmed, E., Kulasinghe, A., Monkman, J., Fletcher, J.A., Mainwaring, P.N., Masud, M.K., Park, H., Hossain, M.S.A., Yamauchi, Y., Sina, A.A.I., Wuethrich, A. and Trau, M. (2023). Extracellular Small Vesicle Phosphorylated PD-L1 Liquid Biopsy Levels Correlate with Tumour Proportion Score (TPS) in NSCLC. 2023 World Conference on Lung Cancer, Singapore, 9-12 September 2023. New York, NY United States: Elsevier. doi: 10.1016/j.jtho.2023.09.432

Extracellular Small Vesicle Phosphorylated PD-L1 Liquid Biopsy Levels Correlate with Tumour Proportion Score (TPS) in NSCLC

2023

Journal Article

Mesoporous Metastable CuTe<sub>2</sub> Semiconductor

Ashok, Aditya, Vasanth, Arya, Nagaura, Tomota, Setter, Caitlin, Clegg, Jack Kay, Fink, Alexander, Masud, Mostafa Kamal, Hossain, Md Shahriar, Hamada, Takashi, Eguchi, Miharu, Phan, Hoang-Phuong and Yamauchi, Yusuke (2023). Mesoporous Metastable CuTe2 Semiconductor. Journal of the American Chemical Society, 145 (43), 23461-23469. doi: 10.1021/jacs.3c05846

Mesoporous Metastable CuTe<sub>2</sub> Semiconductor

2023

Journal Article

Flexible nanoarchitectonics for biosensing and physiological monitoring applications

Ashok, Aditya, Nguyen, Tuan-Khoa, Barton, Matthew, Leitch, Michael, Masud, Mostafa Kamal, Park, Hyeongyu, Truong, Thanh-An, Kaneti, Yusuf Valentino, Ta, Hang Thu, Li, Xiaopeng, Liang, Kang, Do, Thanh Nho, Wang, Chun-Hui, Nguyen, Nam-Trung, Yamauchi, Yusuke and Phan, Hoang-Phuong (2023). Flexible nanoarchitectonics for biosensing and physiological monitoring applications. Small, 19 (9) 2204946, 1-11. doi: 10.1002/smll.202204946

Flexible nanoarchitectonics for biosensing and physiological monitoring applications

2023

Journal Article

Flexible nanoarchitectonics for biosensing and physiological monitoring applications (Small 9/2023)

Ashok, Aditya, Nguyen, Tuan‐Khoa, Barton, Matthew, Leitch, Michael, Masud, Mostafa Kamal, Park, Hyeongyu, Truong, Thanh‐An, Kaneti, Yusuf Valentino, Ta, Hang Thu, Li, Xiaopeng, Liang, Kang, Do, Thanh Nho, Wang, Chun‐Hui, Nguyen, Nam‐Trung, Yamauchi, Yusuke and Phan, Hoang‐Phuong (2023). Flexible nanoarchitectonics for biosensing and physiological monitoring applications (Small 9/2023). Small, 19 (9) 2370053. doi: 10.1002/smll.202370053

Flexible nanoarchitectonics for biosensing and physiological monitoring applications (Small 9/2023)

2023

Book Chapter

Electrochemical biosensor for cancer biomarkers detection

Arifuzzaman, Md, Kamal Masud, Mostafa, Ahmed, Asif, Morsaline Billah, Md and Nazmul Islam, Md (2023). Electrochemical biosensor for cancer biomarkers detection. Current cancer biomarkers. (pp. 349-371) Sharjah, U.A.E: Bentham Science Publishers. doi: 10.2174/9789815079364123010017

Electrochemical biosensor for cancer biomarkers detection

2023

Journal Article

Electrochemical nitrogen fixation in metal-N2 batteries: A paradigm for simultaneous NH3 synthesis and energy generation

Islam, Jahidul, Shareef, Mahmud, Zabed, Hossain M., Qi, Xianghui, Chowdhury, Faisal Islam, Das, Jagotamoy, Uddin, Jamal, Kaneti, Yusuf Valentino, Khandaker, Mayeen Uddin, Idris, Abubakr M., Ullah, Md. Habib and Masud, Mostafa Kamal (2023). Electrochemical nitrogen fixation in metal-N2 batteries: A paradigm for simultaneous NH3 synthesis and energy generation. Energy Storage Materials, 54, 98-119. doi: 10.1016/j.ensm.2022.10.007

Electrochemical nitrogen fixation in metal-N2 batteries: A paradigm for simultaneous NH3 synthesis and energy generation

Funding

Current funding

  • 2024 - 2028
    A nanoarchitectured platform for early diagnosis and monitoring of ovarian cancer
    Cancer Council Queensland
    Open grant
  • 2021 - 2025
    JST-ERATO Yamauchi Materials Space Tectonics
    Japan Science and Technology Agency
    Open grant

Past funding

  • 2024
    Nanoarchitectured platform technology for molecular profiling of exosomes
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2022 - 2023
    Development of Nanoarchitectured Electrodes for High Performance Energy Storage Device
    King Saud University
    Open grant

Supervision

Availability

Dr Mostafa Kamal Masud is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

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