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2019

Journal Article

scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data

Alquicira-Hernandez, Jose, Sathe, Anuja, Ji, Hanlee P., Nguyen, Quan and Powell, Joseph E. (2019). scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data. Genome Biology, 20 (1) 264. doi: 10.1186/s13059-019-1862-5

scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data

2019

Journal Article

SpaCell: integrating tissue morphology and spatial gene expression to predict disease cells

Tan, Xiao, Su, Andrew, Tran, Minh and Nguyen, Quan (2019). SpaCell: integrating tissue morphology and spatial gene expression to predict disease cells. Bioinformatics, 36 (7), 2293-2294. doi: 10.1093/bioinformatics/btz914

SpaCell: integrating tissue morphology and spatial gene expression to predict disease cells

2019

Journal Article

A single-cell transcriptome atlas of the adult human retina

Lukowski, Samuel W., Lo, Camden Y., Sharov, Alexei A., Nguyen, Quan, Fang, Lyujie, Hung, Sandy S. C., Zhu, Ling, Zhang, Ting, Grünert, Ulrike, Nguyen, Tu, Senabouth, Anne, Jabbari, Jafar S., Welby, Emily, Sowden, Jane C., Waugh, Hayley S., Mackey, Adrienne, Pollock, Graeme, Lamb, Trevor D., Wang, Peng-Yuan, Hewitt, Alex W., Gillies, Mark C., Powell, Joseph E. and Wong, Raymond C. B. (2019). A single-cell transcriptome atlas of the adult human retina. The EMBO Journal, 38 (18) e100811, e100811. doi: 10.15252/embj.2018100811

A single-cell transcriptome atlas of the adult human retina

2019

Journal Article

ascend: R package for analysis of single-cell RNA-seq data

Senabouth, Anne, Lukowski, Samuel W., Hernandez, Jose Alquicira, Andersen, Stacey B., Mei, Xin, Nguyen, Quan H. and Powell, Joseph E. (2019). ascend: R package for analysis of single-cell RNA-seq data. GigaScience, 8 (8) giz087. doi: 10.1093/gigascience/giz087

ascend: R package for analysis of single-cell RNA-seq data

2019

Journal Article

Combination of Vaccine Strain Measles Virus and Nimotuzumab in the Treatment of Laryngeal Cancer

Nguyen Linh Toan, , Ngo Thu Hang, , Nguyen Kim Luu, , Can Van Mao, , Nguyen Van Ba, , Nguyen Thi Xuan, , Truong Dinh Cam, , Yamamoto, Naoki, Hoang Van Tong, and Ho Anh Son, (2019). Combination of Vaccine Strain Measles Virus and Nimotuzumab in the Treatment of Laryngeal Cancer. Anticancer Research, 39 (7), 3727-3737. doi: 10.21873/anticanres.13521

Combination of Vaccine Strain Measles Virus and Nimotuzumab in the Treatment of Laryngeal Cancer

2018

Journal Article

Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation

Friedman, Clayton E., Nguyen, Quan, Lukowski, Samuel W., Helfer, Abbigail, Chiu, Han Sheng, Miklas, Jason, Levy, Shiri, Suo, Shengbao, Han, Jing-Dong Jackie, Osteil, Pierre, Peng, Guangdun, Jing, Naihe, Baillie, Greg J., Senabouth, Anne, Christ, Angelika N., Bruxner, Timothy J., Murry, Charles E., Wong, Emily S., Ding, Jun, Wang, Yuliang, Hudson, James, Ruohola-Baker, Hannele, Bar-Joseph, Ziv, Tam, Patrick P.L., Powell, Joseph E. and Palpant, Nathan J. (2018). Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation. Cell Stem Cell, 23 (4), 586-598. doi: 10.1016/j.stem.2018.09.009

Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation

2018

Journal Article

Single-cell profiling identifies key pathways expressed by iPSCs cultured in different commercial media

Daniszewski, Maciej, Nguyen, Quan, Chy, Hun S., Singh, Vikrant, Crombie, Duncan E., Kulkarni, Tejal, Liang, Helena H., Sivakumaran, Priyadharshini, Lidgerwood, Grace E., Hernández, Damián, Conquest, Alison, Rooney, Louise A., Chevalier, Sophie, Andersen, Stacey B., Senabouth, Anne, Vickers, James C., Mackey, David A., Craig, Jamie E., Laslett, Andrew L., Hewitt, Alex W., Powell, Joseph E. and Pébay, Alice (2018). Single-cell profiling identifies key pathways expressed by iPSCs cultured in different commercial media. iScience, 7, 30-39. doi: 10.1016/j.isci.2018.08.016

Single-cell profiling identifies key pathways expressed by iPSCs cultured in different commercial media

2018

Journal Article

Detection of HPV E7 transcription at single-cell resolution in epidermis

Lukowski, S. W., Tuong, Z. K., Noske, K., Senabouth, A., Nguyen, Q. H., Andersen, S. B., Soyer, H. P., Frazer, I. H. and Powell, J. E. (2018). Detection of HPV E7 transcription at single-cell resolution in epidermis. The Journal of Investigative Dermatology, 138 (12), 2558-2567. doi: 10.1016/j.jid.2018.06.169

Detection of HPV E7 transcription at single-cell resolution in epidermis

2018

Journal Article

Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations

Nguyen, Quan H., Lukowski, Samuel W., Chiu, Han Sheng, Senabouth, Anne, Bruxner, Timothy J.C., Christ, Angelika N., Palpant, Nathan J. and Powell, Joseph E. (2018). Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations. Genome Research, 28 (7), 1053-1066. doi: 10.1101/gr.223925.117

Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations

2018

Journal Article

Target-enrichment sequencing for detailed characterization of small RNAs

Nguyen, Quan, Aguado, Julio, Iannelli, Fabio, Suzuki, Ana Maria, Rossiello, Francesca, D'Adda Di Fagagna, Fabrizio and Carninci, Piero (2018). Target-enrichment sequencing for detailed characterization of small RNAs. Nature Protocols, 13 (4), 768-786. doi: 10.1038/nprot.2018.001

Target-enrichment sequencing for detailed characterization of small RNAs

2018

Journal Article

Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data

Nguyen, Quan H., Tellam, Ross L., Naval-Sanchez, Marina, Porto-Neto, Laercio R., Barendse, William, Reverter, Antonio, Hayes, Benjamin, Kijas, James and Dalrymple, Brian P. (2018). Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data. Gigascience, 7 (3), 1-17. doi: 10.1093/gigascience/gix136

Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data

2018

Journal Article

Single cell RNA sequencing of stem cell-derived retinal ganglion cells

Daniszewski, Maciej, Senabouth, Anne, Nguyen, Quan H., Crombie, Duncan E., Lukowski, Samuel W., Kulkarni, Tejal, Sluch, Valentin M., Jabbari, Jafar S., Chamling, Xitiz, Zack, Donald J., Pébay, Alice, Powell, Joseph E. and Hewitt, Alex W. (2018). Single cell RNA sequencing of stem cell-derived retinal ganglion cells. Scientific Data, 5 (1) 180013, 1-9. doi: 10.1038/sdata.2018.13

Single cell RNA sequencing of stem cell-derived retinal ganglion cells

2018

Journal Article

Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds

Naval-Sanchez, Marina, Nguyen, Quan, McWilliam, Sean, Porto-Neto, Laercio R., Tellam, Ross, Vuocolo, Tony, Reverter, Antonio, Perez-Enciso, Miguel, Brauning, Rudiger, Clarke, Shannon, McCulloch, Alan, Zamani, Wahid, Naderi, Saeid, Rezaei, Hamid Reza, Pompanon, Francois, Taberlet, Pierre, Worley, Kim C., Gibbs, Richard A., Muzny, Donna M., Jhangiani, Shalini N., Cockett, Noelle, Daetwyler, Hans and Kijas, James (2018). Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds. Nature Communications, 9 (1) 859. doi: 10.1038/s41467-017-02809-1

Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds

2018

Conference Publication

Genetic networks modulating cell fate specification and contributing to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution

Nguyen, Quan H., Lukowski, Samuel W., Chiu, Han S., Friedman, Clayton E., Senabouth, Anne, Crowhurst, Liam, Bruxner, Timothy J. C., Christ, Angelika N., Hudson, James, Ding, Jun, Bar-Joseph, Ziv, Tam, Patrick P. L., Palpant, Nathan J. and Powell, Joseph E. (2018). Genetic networks modulating cell fate specification and contributing to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution. Human Genome Meeting 2018, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications LLP. doi: 10.1186/s40246-018-0138-6

Genetic networks modulating cell fate specification and contributing to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution

2017

Journal Article

A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

Iannelli, Fabio, Galbiati, Alessandro, Capozzo, Ilaria, Nguyen, Quan, Magnuson, Brian, Michelini, Flavia, D'Alessandro, Giuseppina, Cabrini, Matteo, Roncador, Marco, Francia, Sofia, Crosetto, Nicola, Ljungman, Mats, Carninci, Piero and di Fagagna, Fabrizio d'Adda (2017). A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks. Nature Communications, 8 (1) 15656, 15656. doi: 10.1038/ncomms15656

A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

2017

Journal Article

DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs

Rossiello, Francesca, Aguado, Julio, Sepe, Sara, Iannelli, Fabio, Nguyen, Quan, Pitchiaya, Sethuramasundaram, Carninci, Piero and Di Fagagna, Fabrizio d’Adda (2017). DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs. Nature Communications, 8 (1) 13980, 13980. doi: 10.1038/ncomms13980

DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs

2016

Journal Article

In vitro production of baculoviruses: identifying host and virus genes associated with high productivity

Nguyen, Quan, Tran, Trinh Tb, Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2016). In vitro production of baculoviruses: identifying host and virus genes associated with high productivity. Applied Microbiology and Biotechnology, 100 (21), 1-15. doi: 10.1007/s00253-016-7774-3

In vitro production of baculoviruses: identifying host and virus genes associated with high productivity

2016

Conference Publication

S0125 Changing patterns of genomic variability following domestication of sheep

Sanchez, M. Naval, Brauning, R., Clarke, S. M., Nguyen, Q., McCulloch, A., Cockett, N. E., Zamani, W., Pompanon, F., Taberlet, P., McWilliam, S., Daetwyler, H. and Kijas, J. (2016). S0125 Changing patterns of genomic variability following domestication of sheep. Cary, NC, United States: Oxford University Press. doi: 10.2527/jas2016.94supplement413x

S0125 Changing patterns of genomic variability following domestication of sheep

2016

Conference Publication

Predicting regulatory SNPs within enhancers and promoters in cattle

Nguyen, Q., Tellam, R. L., Kijas, J., Barendse, W. and Dalrymple, B. P. (2016). Predicting regulatory SNPs within enhancers and promoters in cattle. Functional Annotation of Animal Genomes (FAANG) Joint ASAS-ISAG Symposium, Salt Lake City, Utah, United States, July 23 2016. Cary, NC United States: Oxford University Press (OUP). doi: 10.2527/jas2016.94supplement432a

Predicting regulatory SNPs within enhancers and promoters in cattle

2015

Book Chapter

Expression specificity of disease-associated lncRNAs: toward personalized medicine

Nguyen, Quan and Carninci, Piero (2015). Expression specificity of disease-associated lncRNAs: toward personalized medicine. Long non-coding RNAs in human disease. (pp. 237-258) edited by Kevin V. Morris. Cham, Switerland: Springer International Publishing. doi: 10.1007/82_2015_464

Expression specificity of disease-associated lncRNAs: toward personalized medicine