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2023

Journal Article

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

2023

Journal Article

Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated SPP1+ macrophages and fibroblasts

Sathe, Anuja, Mason, Kaishu, Grimes, Susan M., Zhou, Zilu, Lau, Billy T., Bai, Xiangqi, Su, Andrew, Tan, Xiao, Lee, HoJoon, Suarez, Carlos J., Nguyen, Quan, Poultsides, George, Zhang, Nancy R. and Ji, Hanlee P. (2023). Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated SPP1+ macrophages and fibroblasts. Clinical Cancer Research, 29 (1), 244-260. doi: 10.1158/1078-0432.ccr-22-2041

Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated SPP1+ macrophages and fibroblasts

2023

Other Outputs

A robust Platform for Integrative Spatial Multi-omics Analysis to Map Immune Responses to SARS-CoV-2 infection in Lung Tissues

Tan, Xiao and Nguyen, Quan (2023). A robust Platform for Integrative Spatial Multi-omics Analysis to Map Immune Responses to SARS-CoV-2 infection in Lung Tissues. The University of Queensland. (Dataset) doi: 10.48610/1bfc10c

A robust Platform for Integrative Spatial Multi-omics Analysis to Map Immune Responses to SARS-CoV-2 infection in Lung Tissues

2022

Journal Article

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7)

Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2022). Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications, 13 (1) 1200. doi: 10.1038/s41467-022-28758-y

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7)

2022

Conference Publication

Exploratory data analysis of TCGA skin cutaneous melanoma RNA-seq data

Zhang, Min, Arief, Vivi, McLachlan, Geoffrey, Nguyen, Quan and Basford, Kaye (2022). Exploratory data analysis of TCGA skin cutaneous melanoma RNA-seq data. Australasian Applied Statistics Conference (AASC), Inverloch, VIC Australia, 28 November - 2 December 2022.

Exploratory data analysis of TCGA skin cutaneous melanoma RNA-seq data

2022

Journal Article

Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam

Pham, Duy, Truong, Buu, Tran, Khai, Ni, Guiyan, Nguyen, Dat, Tran, Trang T. H., Tran, Mai H., Thuy, Duong Nguyen, Vo, Nam S. and Nguyen, Quan (2022). Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam. Briefings in Bioinformatics, 23 (6) bbac459. doi: 10.1093/bib/bbac459

Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam

2022

Journal Article

A comprehensive evaluation of polygenic score and genotype imputation performances of human SNP arrays in diverse populations

Nguyen, Dat Thanh, Tran, Trang T. H., Tran, Mai Hoang, Tran, Khai, Pham, Duy, Duong, Nguyen Thuy, Nguyen, Quan and Vo, Nam S. (2022). A comprehensive evaluation of polygenic score and genotype imputation performances of human SNP arrays in diverse populations. Scientific Reports, 12 (1) 17556, 1-13. doi: 10.1038/s41598-022-22215-y

A comprehensive evaluation of polygenic score and genotype imputation performances of human SNP arrays in diverse populations

2022

Journal Article

The association between peptic ulcer disease and gastric cancer: results from the Stomach Cancer Pooling (StoP) Project Consortium

Paragomi, Pedram, Dabo, Bashir, Pelucchi, Claudio, Bonzi, Rossella, Bako, Abdulaziz T., Sanusi, Nabila Muhammad, Nguyen, Quan H., Zhang, Zuo-Feng, Palli, Domenico, Ferraroni, Monica, Vu, Khanh Truong, Yu, Guo-Pei, Turati, Federica, Zaridze, David, Maximovitch, Dmitry, Hu, Jinfu, Mu, Lina, Boccia, Stefania, Pastorino, Roberta, Tsugane, Shoichiro, Hidaka, Akihisa, Kurtz, Robert C., Lagiou, Areti, Lagiou, Pagona, Camargo, M. Constanza, Curado, Maria Paula, Lunet, Nuno, Vioque, Jesus, Boffetta, Paolo ... Luu, Hung N. (2022). The association between peptic ulcer disease and gastric cancer: results from the Stomach Cancer Pooling (StoP) Project Consortium. Cancers, 14 (19) 4905, 1-14. doi: 10.3390/cancers14194905

The association between peptic ulcer disease and gastric cancer: results from the Stomach Cancer Pooling (StoP) Project Consortium

2022

Journal Article

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

Tran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

2022

Journal Article

Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions

Naval-Sanchez, Marina, Deshpande, Nikita, Tran, Minh, Zhang, Jingyu, Alhomrani, Majid, Alsanie, Walaa, Nguyen, Quan and Nefzger, Christian M. (2022). Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions. Frontiers in Molecular Biosciences, 9 900323, 1-15. doi: 10.3389/fmolb.2022.900323

Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions

2022

Journal Article

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

Raghubar, Arti M., Pham, Duy T., Tan, Xiao, Grice, Laura F., Crawford, Joanna, Lam, Pui Yeng, Andersen, Stacey B., Yoon, Sohye, Teoh, Siok Min, Matigian, Nicholas A., Stewart, Anne, Francis, Leo, Ng, Monica S. Y., Healy, Helen G., Combes, Alexander N., Kassianos, Andrew J., Nguyen, Quan and Mallett, Andrew J. (2022). Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments. Frontiers in Medicine, 9 873923, 873923. doi: 10.3389/fmed.2022.873923

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

2022

Journal Article

LmTag: functional-enrichment and imputation-aware tag SNP selection for population-specific genotyping arrays

Nguyen, Dat Thanh, Nguyen, Quan Hoang, Duong, Nguyen Thuy and Vo, Nam S. (2022). LmTag: functional-enrichment and imputation-aware tag SNP selection for population-specific genotyping arrays. Briefings in Bioinformatics, 23 (4) bbac252, 1-12. doi: 10.1093/bib/bbac252

LmTag: functional-enrichment and imputation-aware tag SNP selection for population-specific genotyping arrays

2022

Conference Publication

Abstract 3817: A single-cell, spatial multiomics atlas and cellular interactome of all major skin cancer types

Grice, Laura, Ni, Guiyan, Jin, Xinnan, Tran, Minh, Killingbeck, Emily, Gregory, Mark, Mulay, Onkar, Teoh, Siok-Min, Kulasinghe, Arutha, Leon, Michael, Murphy, Sarah, Warren, Sarah, Kim, Youngmi and Nguyen, Quan (2022). Abstract 3817: A single-cell, spatial multiomics atlas and cellular interactome of all major skin cancer types. American Association for Cancer Research Annual Meeting, Philadelphia, PA, United States, 8-13 April 2022. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2022-3817

Abstract 3817: A single-cell, spatial multiomics atlas and cellular interactome of all major skin cancer types

2022

Conference Publication

MEDB-06. Spatial transcriptomic analysis of Sonic Hedgehog Medulloblastoma identifies that loss of heterogeneity and induced differentiation underlies the response to CDK4/6 inhibition

Vo, Tuan, Balderson, Brad, Jones, Kahli, Crawford, Joanna, Millar, Amanda, Tolson, Elissa, Ruitenberg, Marc, Robertson, Thomas, Bhuva, Dharmesh, Davis, Melissa, Wainwright, Brandon, Nguyen, Quan and Genovesi, Laura (2022). MEDB-06. Spatial transcriptomic analysis of Sonic Hedgehog Medulloblastoma identifies that loss of heterogeneity and induced differentiation underlies the response to CDK4/6 inhibition. International Symposium on Pediatric Neuro-Oncology, Hamburg, Germany, 12–15 June 2022. Cary, NC, United States: Oxford University Press. doi: 10.1093/neuonc/noac079.381

MEDB-06. Spatial transcriptomic analysis of Sonic Hedgehog Medulloblastoma identifies that loss of heterogeneity and induced differentiation underlies the response to CDK4/6 inhibition

2022

Journal Article

A deep learning model for molecular label transfer that enables cancer cell identification from histopathology images

Su, Andrew, Lee, HoJoon, Tan, Xiao, Suarez, Carlos J., Andor, Noemi, Nguyen, Quan and Ji, Hanlee P. (2022). A deep learning model for molecular label transfer that enables cancer cell identification from histopathology images. npj Precision Oncology, 6 (1) 14, 14. doi: 10.1038/s41698-022-00252-0

A deep learning model for molecular label transfer that enables cancer cell identification from histopathology images

2022

Conference Publication

Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, D., Clayton, Z., Prowse, A., Dingwall, S., George, J., Shah, H., Paterson, H., Jeyaprakesh, P., Wu, Z., Campbell, T., Kotake, Y., Turnbull, S., Nguyen, Q., Grieve, S., Palpant, N., Pathan, F., Kizana, E., Kumar, S., Gray, P. and Chong, J. (2022). Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD Australia, 11-14 August 2022. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.004

Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

2021

Journal Article

Resolving the immune landscape of human prostate at a single-cell level in health and cancer

Tuong, Zewen Kelvin, Loudon, Kevin W., Berry, Brendan, Richoz, Nathan, Jones, Julia, Tan, Xiao, Nguyen, Quan, George, Anne, Hori, Satoshi, Field, Sarah, Lynch, Andy G., Kania, Katarzyna, Coupland, Paul, Babbage, Anne, Grenfell, Richard, Barrett, Tristan, Warren, Anne Y., Gnanapragasam, Vincent, Massie, Charlie and Clatworthy, Menna R. (2021). Resolving the immune landscape of human prostate at a single-cell level in health and cancer. Cell Reports, 37 (12) 110132, 110132. doi: 10.1016/j.celrep.2021.110132

Resolving the immune landscape of human prostate at a single-cell level in health and cancer

2021

Journal Article

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2021). Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nature Communications, 12 (1) 3297. doi: 10.1038/s41467-021-23143-7

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

2021

Journal Article

Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation

Shen, Sophie, Sun, Yuliangzi, Matsumoto, Maika, Shim, Woo Jun, Sinniah, Enakshi, Wilson, Sean B., Werner, Tessa, Wu, Zhixuan, Bradford, Stephen T., Hudson, James, Little, Melissa H., Powell, Joseph, Nguyen, Quan and Palpant, Nathan J. (2021). Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation. Trends in Molecular Medicine, 27 (12), 1135-1158. doi: 10.1016/j.molmed.2021.09.006

Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation

2021

Journal Article

A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia

Tuong, Zewen K., Lukowski, Samuel W., Nguyen, Quan H., Chandra, Janin, Zhou, Chenhao, Gillinder, Kevin, Bashaw, Abate A., Ferdinand, John R., Stewart, Benjamin J., Teoh, Siok Min, Hanson, Sarah J., Devitt, Katharina, Clatworthy, Menna R., Powell, Joseph E. and Frazer, Ian H. (2021). A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia. iScience, 24 (11) 103326, 103326. doi: 10.1016/j.isci.2021.103326

A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia