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2024

Conference Publication

A spatially mapped gene expression signature for intestinal stem-like cells identifies high-risk precursors of gastric cancer

Wichmann, Ignacio A., Huang, Robert J., Su, Andrew, Sathe, Anuja, Shum, Miranda V., Grimes, Susan M., Meka, Rithika, Almeda, Alison, Bai, Xiangqi, Shen, Jeanne, Nguyen, Quan, Amieva, Manuel, Hwang, Joo Ha and Ji, Hanlee P. (2024). A spatially mapped gene expression signature for intestinal stem-like cells identifies high-risk precursors of gastric cancer. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-1140

A spatially mapped gene expression signature for intestinal stem-like cells identifies high-risk precursors of gastric cancer

2024

Journal Article

Genome-wide transcriptome analysis reveals the diversity and function of long non-coding RNAs in dinoflagellates

Chen, Yibi, Dougan, Katherine E., Nguyen, Quan, Bhattacharya, Debashish and Chan, Cheong Xin (2024). Genome-wide transcriptome analysis reveals the diversity and function of long non-coding RNAs in dinoflagellates. NAR Genomics and Bioinformatics, 6 (1) lqae016, lqae016. doi: 10.1093/nargab/lqae016

Genome-wide transcriptome analysis reveals the diversity and function of long non-coding RNAs in dinoflagellates

2024

Journal Article

Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems

Gillespie, Ellen R., Grice, Laura F., Courtney, Isabel G., Lao, Hong Wa, Jung, Woncheol, Ramkomuth, Sonny, Xie, Jacky, Brown, David A., Walsham, James, Radford, Kristen J., Nguyen, Quan H. and Ruitenberg, Marc J. (2024). Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems. Journal of Neuroinflammation, 21 (1) 63, 1-20. doi: 10.1186/s12974-024-03048-0

Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems

2024

Journal Article

Large thermoelectric effects in p-SiC/p-Si and n-SiC/p-Si heterojunctions

Guzman, Pablo, Dinh, Toan, Nguyen, Thanh, Foisal, Abu Riduan Md, Nguyen, Hung, Nguyen, Quan, Nguyen, Tuan-Khoa, Phan, Hoang-Phuong, Tanner, Philip, Woodfield, Peter, Dau, Van Thanh, Li, Huaizhong, Nguyen, Nam-Trung and Dao, Dzung Viet (2024). Large thermoelectric effects in p-SiC/p-Si and n-SiC/p-Si heterojunctions. Materials Today Communications, 38 108493. doi: 10.1016/j.mtcomm.2024.108493

Large thermoelectric effects in p-SiC/p-Si and n-SiC/p-Si heterojunctions

2024

Journal Article

Challenges and perspectives in computational deconvolution of genomics data

Garmire, Lana X., Li, Yijun, Huang, Qianhui, Xu, Chuan, Teichmann, Sarah A., Kaminski, Naftali, Pellegrini, Matteo, Nguyen, Quan and Teschendorff, Andrew E. (2024). Challenges and perspectives in computational deconvolution of genomics data. Nature Methods, 21 (3), 391-400. doi: 10.1038/s41592-023-02166-6

Challenges and perspectives in computational deconvolution of genomics data

2024

Other Outputs

DeepHis2Exp

Jiang, Yuanhao, Nguyen, Quan and Tan, Xiao (2024). DeepHis2Exp. The University of Queensland. (Dataset) doi: 10.48610/3e7a235

DeepHis2Exp

2024

Journal Article

Cellular neighborhood analysis in spatial omics reveals new tissue domains and cell subtypes

Ruitenberg, Marc J. and Nguyen, Quan H. (2024). Cellular neighborhood analysis in spatial omics reveals new tissue domains and cell subtypes. Nature Genetics, 56 (3), 362-364. doi: 10.1038/s41588-023-01646-x

Cellular neighborhood analysis in spatial omics reveals new tissue domains and cell subtypes

2024

Journal Article

Association of UGT1A1 gene variants, expression levels, and enzyme concentrations with 2,3,7,8-TCDD exposure in individuals exposed to Agent Orange/Dioxin

Quang, Ha Van, Vuong, Nguyen Ba, Trang, Bui Ngoc Linh, Toan, Nguyen Linh and Tong, Hoang Van (2024). Association of UGT1A1 gene variants, expression levels, and enzyme concentrations with 2,3,7,8-TCDD exposure in individuals exposed to Agent Orange/Dioxin. Scientific Reports, 14 (1) 3315. doi: 10.1038/s41598-024-54004-0

Association of UGT1A1 gene variants, expression levels, and enzyme concentrations with 2,3,7,8-TCDD exposure in individuals exposed to Agent Orange/Dioxin

2024

Journal Article

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, Dinesh, Clayton, Zoe E., Prowse, Andrew, Dingwall, Steve, Kim, Sul Ki, Reyes, Leila, George, Jacob, Shah, Haisam, Chen, Siqi, Leung, Halina H. L., Hume, Robert D., Tjahjadi, Laurentius, Igoor, Sindhu, Skelton, Rhys J. P., Hing, Alfred, Paterson, Hugh, Foster, Sheryl L., Pearson, Lachlan, Wilkie, Emma, Marcus, Alan D., Jeyaprakash, Prajith, Wu, Zhixuan, Chiu, Han Shen, Ongtengco, Cherica Felize J., Mulay, Onkar, McArthur, Jeffrey R., Barry, Tony, Lu, Juntang, Tran, Vu ... Chong, James J. H. (2024). Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. Nature Cardiovascular Research, 3 (2), 145-165. doi: 10.1038/s44161-023-00419-3

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

2024

Journal Article

HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function

Friedman, Clayton E., Cheetham, Seth W., Negi, Sumedha, Mills, Richard J., Ogawa, Masahito, Redd, Meredith A., Chiu, Han Sheng, Shen, Sophie, Sun, Yuliangzi, Mizikovsky, Dalia, Bouveret, Romaric, Chen, Xiaoli, Voges, Holly K., Paterson, Scott, De Angelis, Jessica E., Andersen, Stacey B., Cao, Yuanzhao, Wu, Yang, Jafrani, Yohaann M.A., Yoon, Sohye, Faulkner, Geoffrey J., Smith, Kelly A., Porrello, Enzo, Harvey, Richard P., Hogan, Benjamin M., Nguyen, Quan, Zeng, Jian, Kikuchi, Kazu, Hudson, James E. and Palpant, Nathan J. (2024). HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function. Developmental Cell, 59 (1), 91-107.e6. doi: 10.1016/j.devcel.2023.11.012

HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function

2024

Journal Article

Clinicopathologic characteristics of thyroid microcarcinoma: findings from a hospital-based study in Vietnam

Nguyen, Bay Quang, Vu, Hai Thi, Nguyen, Linh My Thi, Nguyen, Quan H., Paragomi, Pedram and Luu, Hung N. (2024). Clinicopathologic characteristics of thyroid microcarcinoma: findings from a hospital-based study in Vietnam. Discovery Medicine, 36 (180), 209-216. doi: 10.24976/discov.med.202436180.20

Clinicopathologic characteristics of thyroid microcarcinoma: findings from a hospital-based study in Vietnam

2024

Journal Article

The 1% gift to humanity: The Human Genome Project II

Liu, Weibin, Li, Yan, Patrinos, George P., Xu, Shuhua, Thong, Meow-Keong, Chen, Zhengming, Crawley, Francis P., Li, Liming, Ekmekci, Perihan Elif, Drmanac, Radoje, Cheong, Weiyang, Benamouzig, Robert, Nguyen, Quan, Volchkov, Pavel, Reichardt, Juergen K. V., Carninci, Piero, Majumder, Partha, Jin, Xin, Church, George, Wang, Jian and Xu, Xun (2024). The 1% gift to humanity: The Human Genome Project II. Cell Research, 34 (11), 747-750. doi: 10.1038/s41422-024-01026-y

The 1% gift to humanity: The Human Genome Project II

2023

Journal Article

Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

Pham, Duy, Tan, Xiao, Balderson, Brad, Xu, Jun, Grice, Laura F., Yoon, Sohye, Willis, Emily F., Tran, Minh, Lam, Pui Yeng, Raghubar, Arti, Kalita-de Croft, Priyakshi, Lakhani, Sunil, Vukovic, Jana, Ruitenberg, Marc J. and Nguyen, Quan H. (2023). Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues. Nature Communications, 14 (1) 7739, 1-25. doi: 10.1038/s41467-023-43120-6

Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

2023

Journal Article

Deep spatial-omics analysis of Head & Neck carcinomas provides alternative therapeutic targets and rationale for treatment failure

Causer, Andrew, Tan, Xiao, Lu, Xuehan, Moseley, Philip, Teoh, Siok M., Molotkov, Natalie, McGrath, Margaret, Kim, Taehyun, Simpson, Peter T., Perry, Christopher, Frazer, Ian H., Panizza, Benedict, Ladwa, Rahul, Nguyen, Quan and Gonzalez-Cruz, Jazmina L. (2023). Deep spatial-omics analysis of Head & Neck carcinomas provides alternative therapeutic targets and rationale for treatment failure. n p j Precision Oncology, 7 (1) 89, 1-13. doi: 10.1038/s41698-023-00444-2

Deep spatial-omics analysis of Head & Neck carcinomas provides alternative therapeutic targets and rationale for treatment failure

2023

Journal Article

Tolerogenic dendritic cells protect against acute kidney injury

Li, Jennifer S.Y., Robertson, Harry, Trinh, Katie, Raghubar, Arti M., Nguyen, Quan, Matigian, Nicholas, Patrick, Ellis, Thomson, Angus W., Mallett, Andrew J. and Rogers, Natasha M. (2023). Tolerogenic dendritic cells protect against acute kidney injury. Kidney International, 104 (3), 492-507. doi: 10.1016/j.kint.2023.05.008

Tolerogenic dendritic cells protect against acute kidney injury

2023

Journal Article

A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues

Tan, Xiao, Grice, Laura F., Tran, Minh, Mulay, Onkar, Monkman, James, Blick, Tony, Vo, Tuan, Almeida, Ana Clara, da Silva Motta, Jarbas, Fernandes de Moura, Karen, Machado‐Souza, Cleber, Souza‐Fonseca‐Guimaraes, Paulo, Baena, Cristina Pellegrino, de Noronha, Lucia, Guimaraes, Fernanda Simoes Fortes, Luu, Hung N., Drennon, Tingsheng, Williams, Stephen, Stern, Jacob, Uytingco, Cedric, Pan, Liuliu, Nam, Andy, Cooper, Caroline, Short, Kirsty, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Kulasinghe, Arutha and Nguyen, Quan (2023). A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues. Immunology, 170 (3), 401-418. doi: 10.1111/imm.13679

A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues

2023

Journal Article

Global analysis of transcription start sites and enhancers in endometrial stromal cells and differences associated with endometriosis

Marla, Sushma, Mortlock, Sally, Yoon, Sohye, Crawford, Joanna, Andersen, Stacey, Mueller, Michael D., McKinnon, Brett, Nguyen, Quan and Montgomery, Grant W. (2023). Global analysis of transcription start sites and enhancers in endometrial stromal cells and differences associated with endometriosis. Cells, 12 (13) 1736, 1-22. doi: 10.3390/cells12131736

Global analysis of transcription start sites and enhancers in endometrial stromal cells and differences associated with endometriosis

2023

Journal Article

In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting

Tu, Wen Juan, Melino, Michelle, Dunn, Jenny, McCuaig, Robert D., Bielefeldt-Ohmann, Helle, Tsimbalyuk, Sofiya, Forwood, Jade K., Ahuja, Taniya, Vandermeide, John, Tan, Xiao, Tran, Minh, Nguyen, Quan, Zhang, Liang, Nam, Andy, Pan, Liuliu, Liang, Yan, Smith, Corey, Lineburg, Katie, Nguyen, Tam H., Sng, Julian D. J., Tong, Zhen Wei Marcus, Chew, Keng Yih, Short, Kirsty R., Le Grand, Roger, Seddiki, Nabila and Rao, Sudha (2023). In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting. Nature Communications, 14 (1) 3680, 3680. doi: 10.1038/s41467-023-39341-4

In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting

2023

Other Outputs

Deep spatial-omics analysis of head & neck carcinomas provides alternative therapeutic targets and rational for treatment failure

Andrew Causer, Xiao Tan, Xuehan Lu, Philip Moseley, Min Teoh, Natalie Molotkov, Margaret McGrath, Taehyun Kim, Peter Simpson, Christopher Perry, Ian Frazer, Benedict Panizza, Rahul Ladwa, Quan Nguyen and Jazmina L Gonzalez-Cruz (2023). Deep spatial-omics analysis of head & neck carcinomas provides alternative therapeutic targets and rational for treatment failure. The University of Queensland. (Dataset) doi: 10.48610/698bb9e

Deep spatial-omics analysis of head & neck carcinomas provides alternative therapeutic targets and rational for treatment failure

2023

Journal Article

Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition

Vo, Tuan, Balderson, Brad, Jones, Kahli, Ni, Guiyan, Crawford, Joanna, Millar, Amanda, Tolson, Elissa, Singleton, Matthew, Kojic, Marija, Robertson, Thomas, Walters, Shaun, Mulay, Onkar, Bhuva, Dharmesh D., Davis, Melissa J., Wainwright, Brandon J., Nguyen, Quan and Genovesi, Laura A. (2023). Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition. Genome Medicine, 15 (1) 29, 29. doi: 10.1186/s13073-023-01185-4

Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition