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2018

Journal Article

Development of a Multiplexed Microsphere PCR for Culture-Free Detection and Gram-Typing of Bacteria in Human Blood Samples

Liang, Fang, Browne, Daniel J., Gray, Megan J., Gartlan, Kate H., Smith, David D., Barnard, Ross T., Hill, Geoffrey R., Corrie, Simon R. and Markey, Kate A. (2018). Development of a Multiplexed Microsphere PCR for Culture-Free Detection and Gram-Typing of Bacteria in Human Blood Samples. ACS Infectious Diseases, 4 (5), 837-844. doi: 10.1021/acsinfecdis.7b00277

Development of a Multiplexed Microsphere PCR for Culture-Free Detection and Gram-Typing of Bacteria in Human Blood Samples

2017

Journal Article

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion

Lynch, Jason P., Werder, Rhiannon B., Loh, Zhixuan, Sikder, Md Al Amin, Curren, Bodie, Zhang, Vivian, Rogers, Matthew J. , Lane, Katie, Simpson, Jennifer, Mazzone, Stuart B., Spann, Kirsten, Hayball, John, Diener, Kerrilyn, Everard, Mark L., Blyth, Christopher C., Forstner, Christian, Dennis, Paul G., Murtaza, Nida, Morrison, Mark, Ó Cuív, Páraic, Zhang, Ping, Haque, Ashraful, Hill, Geoffrey R., Sly, Peter D., Upham, John W. and Phipps, Simon (2017). Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of Experimental Medicine, 215 (2), 537-557. doi: 10.1084/jem.20170298

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion

2017

Journal Article

Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience

Mediwake, Heshani, Curley, Cameron, Butler, Jason, McLean, Angela, Tey, Siok, Hill, Geoffrey R., Morton, Anthony, Misra, Ashish, Subramoniapillai, Elango, Durrant, Simon and Kennedy, Glen A. (2017). Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience. Blood Cancer Journal, 7 (12) 55, 1-4. doi: 10.1038/s41408-017-0012-0

Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience

2017

Journal Article

Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK-cell suppression of metastasis

Mittal, Deepak, Vijayan, Dipti, Putz, Eva M., Aguilera, Amelia R., Markey, Kate A., Straube, Jasmin, Kazakoff, Stephen, Nutt, Stephen L., Takeda, Kazuyoshi, Hill, Geoffrey R., Waddell, Nicola and Smyth, Mark J. (2017). Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK-cell suppression of metastasis. Cancer Immunology Research, 5 (12), 1098-1108. doi: 10.1158/2326-6066.CIR-17-0341

Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK-cell suppression of metastasis

2017

Journal Article

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

Gartlan, Kate H., Bommiasamy, Hemamalini, Paz, Katelyn, Wilkinson, Andrew N., Owen, Mary, Reichenbach, Dawn K., Banovic, Tatjana, Wehner, Kimberly, Buchanan, Faith, Varelias, Antiopi, Kuns, Rachel D., Chang, Karshing, Fedoriw, Yuri, Shea, Thomas, Coghill, James, Zaiken, Michael, Plank, Maximilian W., Foster, Paul S., Clouston, Andrew D., Blazar, Bruce R., Serody, Jonathan S. and Hill, Geoffrey R. (2017). A critical role for donor-derived IL-22 in cutaneous chronic GVHD. American Journal of Transplantation , 18 (4), 810-820. doi: 10.1111/ajt.14513

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

2017

Journal Article

IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection

Sebina, I., Fogg, L. G., James, K. R., Soon, M. S. F., Akter, J., Thomas, B. S., Hill, G. R., Engwerda, C. R. and Haque, A. (2017). IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection. Parasite Immunology, 39 (10) e12455, e12455. doi: 10.1111/pim.12455

IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection

2017

Journal Article

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

Porter, Amy H., Leveque-El Mouttie, Lucie, Vu, Therese, Bruedigam, Claudia, Sutton, Joanne, Jacquelin, Sebastien, Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2017). Acute myeloid leukemia stem cell function is preserved in the absence of autophagy. Haematologica, 102 (9), E344-E347. doi: 10.3324/haematol.2017.166389

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

2017

Journal Article

Cytokine mediators of chronic graft-versus-host disease

MacDonald, Kelli P. A., Blazar, Bruce R. and Hill, Geoffrey R. (2017). Cytokine mediators of chronic graft-versus-host disease. Journal of Clinical Investigation, 127 (7), 2452-2463. doi: 10.1172/JCI90593

Cytokine mediators of chronic graft-versus-host disease

2017

Journal Article

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

AL-Kouba, Jane, Wilkinson, Andrew N., Starkey, Malcolm R., Rudraraju, Rajeev, Werder, Rhiannon B., Liu, Xiao, Law, Soi-Cheng, Horvat, Jay C., Brooks, Jeremy F., Hill, Geoffrey R., Davies, Janet M., Phipps, Simon, Hansbro, Philip M. and Steptoe, Raymond J. (2017). Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation. JCI Insight, 2 (11) e85742. doi: 10.1172/jci.insight.85742

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

2017

Journal Article

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

Forcade, Edouard, Paz, Katelyn, Flynn, Ryan, Griesenauer, Brad, Amet, Tohti, Li, Wei, Liu, Liangyi, Bakoyannis, Giorgos, Jiang, Di, Chu, Hong Wei, Lobera, Mercedes, Yang, Jianfei, Wilkes, David S., Du, Jing, Gartlan, Kate, Hill, Geoffrey R., MacDonald, Kelli P. A., Espada, Eduardo L., Blanco, Patrick, Serody, Jonathan S., Koreth, John, Cutler, Corey S., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Paczesny, Sophie and Blazar, Bruce R. (2017). An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition. JCI Insight, 2 (12) e92111. doi: 10.1172/jci.insight.92111

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

2017

Journal Article

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production

Du, Jing, Paz, Katelyn, Flynn, Ryan, Vulic, Ante, Robinson, Tara M., Lineburg, Katie E., Alexander, Kylie A., Meng, Jingjing, Roy, Sabita, Panoskaltsis-Mortari, Angela, Loschi, Michael, Hill, Geoffrey R., Serody, Jonathan S., Maillard, Ivan, Miklos, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, MacDonald, Kelli P., Schacker, Timothy W., Luznik, Leo and Blazar, Bruce R. (2017). Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production. Blood, 129 (18), 2570-2580. doi: 10.1182/blood-2017-01-758854

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production

2017

Journal Article

Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?

Snowden, John A. and Hill, Geoffrey R. (2017). Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?. British Journal of Haematology, 177 (3), 341-342. doi: 10.1111/bjh.14565

Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?

2017

Journal Article

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

2017

Journal Article

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

Vuckovic, Slavica, Vandyke, Kate, Rickards, David A., Mccauley Winter, Padraig, Brown, Simon H. J., Mitchell, Todd W., Liu, Jun, Lu, Jun, Askenase, Philip W., Yuriev, Elizabeth, Capuano, Ben, Ramsland, Paul A., Hill, Geoffrey R., Zannettino, Andrew C. W. and Hutchinson, Andrew T. (2017). The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells. British Journal of Haematology, 177 (3), 423-440. doi: 10.1111/bjh.14561

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

2017

Journal Article

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT

Gartlan, Kate H., Varelias, Antiopi, Koyama, Motoko, Robb, Renee J., Markey, Kate A., Chang, Karshing, Wilkinson, Andrew N., Smith, David, Ullah, Md Ashik, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Teal, Bianca E., Cheong, Melody, Teng, Michele W. L., Smyth, Mark J., Tey, Siok-Keen, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2017). Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT. Blood Advances, 1 (6), 341-351. doi: 10.1182/bloodadvances.2016002980

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT

2017

Journal Article

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2017). GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood, 129 (5), 630-642. doi: 10.1182/blood-2016-08-734020

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

2017

Journal Article

Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance

Hill, Geoffrey R. (2017). Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance. Transplantation, 101 (2), 232-233. doi: 10.1097/TP.0000000000001550

Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance

2017

Journal Article

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P. A ., Hugenholtz, Philip and Hill, Geoffrey R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Blood, 129 (15), 2172-2185. doi: 10.1182/blood-2016-08-732628

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

2017

Journal Article

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

MacDonald, Kelli P. A., Hill, Geoffrey R. and Blazar, Bruce R. (2017). Chronic graft-versus-host disease: biological insights from preclinical and clinical studies. Blood, 129 (1), 13-21. doi: 10.1182/blood-2016-06-686618

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

2016

Journal Article

Novel platform technology for modular mucosal vaccine that protects against streptococcus

Zaman, Mehfuz, Ozberk, Victoria, Langshaw, Emma L., McPhun, Virginia, Powell, Jessica L., Phillips, Zachary N., Ho, Mei Fong, Calcutt, Ainslie, Batzloff, Michael R., Toth, Istvan, Hill, Geoffrey R., Pandey, Manisha and Good, Michael F. (2016). Novel platform technology for modular mucosal vaccine that protects against streptococcus. Scientific Reports, 6 (1) 39274, 1-11. doi: 10.1038/srep39274

Novel platform technology for modular mucosal vaccine that protects against streptococcus