
Overview
Background
I completed a BSc (Hons) and a PhD at the University of Melbourne before undertaking post-doctoral research at the University of California, Berkeley, and the University of Texas MD Anderson Cancer Center, Houston. My research focused on marsupial and eutherian developmental biology. After 6 years in the US I returned to Australia to study Veterinary Science (BVSc) at the University of Queensland (UQ), going on to work in equine and small animal practice. A longing to get back into research lead to my current position as a Teaching & Research academic in the School of Veterinary Science, UQ. My lab has generated induced pluripotent stem cells (iPSCs) from dogs and horses that are being used to model diseases in vitro and as the basis for research into stem cell-based treatments for a variety of diseases. We have also produced iPSCs from the Tasmanian devil and the platypus, the first stem cells ever described from a marsupial and a monotreme, respectively, allowing us to pursue research directed at treating devil facial tumour disease, understanding marsupial and monotreme embryonic development, and the conservation of endangered species.
Education
- BSc (Hons), University of Melbourne (1990)
- PhD, University of Melbourne (1996)
- BVSc (Hons), University of Queensland (2006)
Employment
- Post-doctoral researcher, University of California, Berkeley, USA (1996-1997)
- Post-doctoral researcher, MD Anderson Cancer Centre, Houston, Texas, USA (1997-2002)
- Veterinary Surgeon (2006-present)
- Lecturer, School of Veterinary Science, University of Queensland (2010-2017)
- Affiliate Senior Research Fellow, Australian Institute for Bioengineering and Nanotechnology, University of Queensland (2016-present)
- Senior Lecturer, School of Veterinary Science, University of Queensland (2017-2022)
- Associate Professor, School of Veterinary Science, University of Queensland (2023-present)
Availability
- Associate Professor Deanne Whitworth is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Melbourne
- Doctor of Philosophy, University of Melbourne
- Bachelor (Honours) of Veterinary Science, The University of Queensland
Research interests
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Induced pluripotent stem cells from domestic and native Australian species
Our research uses induced pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) from domestic and native Australian species to address several key areas of research including regenerative medicine, reproduction, species conservation and mammalian evolution.
Works
Search Professor Deanne Whitworth’s works on UQ eSpace
2015
Conference Publication
Stem cell therapies for treating osteoarthritis: prescient or premature?
Whitworth, Deanne (2015). Stem cell therapies for treating osteoarthritis: prescient or premature?. Australian and New Zealand College of Veterinary Scientists College Science Week Conference, Gold Coast, QLD, Australia, 9-11 July 2015.
2015
Conference Publication
Platypus Induced Pluripotent Stem Cells Reveal that Acquisition of SOX2 Responsiveness Facilitated Expansion of the Pluripotency Network During Mammalian Evolution
Whitworth, D. J., Gauthier, M.-E., Ovchinnikov, D. A., Grimmond, S. M., Marshall Graves, J. A. and Wolvetang, E. J. (2015). Platypus Induced Pluripotent Stem Cells Reveal that Acquisition of SOX2 Responsiveness Facilitated Expansion of the Pluripotency Network During Mammalian Evolution. Annual Meeting of the International Society for Stem Cell Research, Stockholm , Sweden, 24-27 June 2015.
2013
Conference Publication
FGF/ERK signalling induces X chromosome inactivation in LIF-dependent equine induced pluripotent stem cells
Whitworth, Deanne J., Ovchinnikov, Dmitry A., Sun, Jane, Fortuna, Patrick R. J. and Wolvetang, Ernst J. (2013). FGF/ERK signalling induces X chromosome inactivation in LIF-dependent equine induced pluripotent stem cells. ASSCR 2013: 6th Annual Meeting for Australasian Society for Stem Cell Research, South Bank, QLD, Australia, 27-29 October, 2013.
2012
Conference Publication
The generation of induced pluripotent stem cells from human CD34+ cells reveals a sex bias in reprogramming efficiency
Whitworth, D. J., Sun, J and Wolvetang, E. J. (2012). The generation of induced pluripotent stem cells from human CD34+ cells reveals a sex bias in reprogramming efficiency. Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13-16 June 2012.
2000
Conference Publication
Sox9 and Sertoli cell differentiation in the mouse
Whitworth, D. J., Bi, W., Deng, J. M., de Crombrugghe, B. and Behringer, R. R. (2000). Sox9 and Sertoli cell differentiation in the mouse. Second International Symposium on the Biology of Vertebrate Sex Determination, Hawaii, U.S.A., xx.
1998
Conference Publication
An analysis of the behaviour of Sox9 mutant cells in testicular development
Whitworth, D. J., Bi, W., Deng, J. M., de Crombrugghe, B. and Behringer, R. R. (1998). An analysis of the behaviour of Sox9 mutant cells in testicular development. Cold Spring Harbor Meeting on Mouse Molecular Genetics, Cold Spring Harbor Laboratory, New York, xx.
1998
Conference Publication
Testis-like steroidogenesis in the ovotestis of the European mole
Whitworth, Deanne, Licht, .P, Racey, P. A. and Glickman, S. E. (1998). Testis-like steroidogenesis in the ovotestis of the European mole. Society for the Study of Reproduction, Ann Arbor, MI, xx. Society for the Study of Reproduction: Madison, WI, United States.
1995
Conference Publication
Sexual differentiation in marsupial mammals
Renfree, Marilyn B., Shaw, Geoffrey, Harry, Jenny L. and Whitworth, Deanne J. (1995). Sexual differentiation in marsupial mammals. Keystone Symposium on the Molecular Basis for the Differences Between the Sexes, Tamarron, CO, U.S.A., 12-18 February 1995.
1994
Conference Publication
Müllerian inhibiting substance gene expression in the developing gonad of the tammar wallaby (Macropus eugenii)
Whitworth, D. J., Harry, J. L., Shaw, G. and Renfree, M. B. (1994). Müllerian inhibiting substance gene expression in the developing gonad of the tammar wallaby (Macropus eugenii). Society for the Study of Reproduction and Fertility, Southhampton, UK, xx.
1994
Conference Publication
Müllerian inhibiting substance gene expression in the developing testis of the tammar wallaby (Macropus eugenii)
Whitworth, Deanne, Harry, J. L., Shaw, G. and Renfree, M. B. (1994). Müllerian inhibiting substance gene expression in the developing testis of the tammar wallaby (Macropus eugenii). Australian Society for Reproductive Biology, Sydney , Australia, xx.
1994
Conference Publication
Gonadal sex reversal in female tammar wallabies is induced by MIS
Whitworth, D. J. and Renfree, M. B. (1994). Gonadal sex reversal in female tammar wallabies is induced by MIS. Australian Society for Reproductive Biology and the Endocrine Society of Australia Annual Scientific Meeting, Sydney, NSW, Australia, 30 September-2 October 1991. Perth, WA, Australia: Australian Society for Reproductive Biology.
1992
Conference Publication
Density of adrenergic nerves about guinea-pig intrapulmonary arterial smooth muscle increases with decreasing vessel diameter
Whitworth, D. J. and McLean, J. R. (1992). Density of adrenergic nerves about guinea-pig intrapulmonary arterial smooth muscle increases with decreasing vessel diameter. The 55th Meeting of the Australian Physiological and Pharmacological Society jointly with the Australian and New Zealand Society of Neplanology, Melbourne, VIC, Australia, 27-28 February 1992. St. Lucia, QLD, Australia: Australian Physiological and Pharmacological Society.
Funding
Current funding
Supervision
Availability
- Associate Professor Deanne Whitworth is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Projects working with marsupial (Tasmanian devil) and horse stem cells are currently available
Supervision history
Current supervision
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Doctor Philosophy
Genetic engineering in Tasmanian devil stem cells to deliver targeted anti-tumour activity against devil facial tumour cells
Principal Advisor
Other advisors: Associate Professor Gry Boe-Hansen
-
Doctor Philosophy
In vitro modelling and treatment of laminitis using equine stem cells
Principal Advisor
Other advisors: Associate Professor Francois-Rene Bertin, Dr Albert Sole Guitart
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Doctor Philosophy
The Oncogenic and Immunosuppresive Potency of Novel Flying Fox Gammaretrovirus : Uncover The Species-Shifting of Bat Virus Origin
Associate Advisor
Other advisors: Professor Joanne Meers, Dr Lee McMichael
Completed supervision
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2020
Doctor Philosophy
A stem cell-based approach to the treatment of devil facial tumour disease (DFTD) in the Tasmanian devil (Sarcophilus harrisii)
Principal Advisor
Other advisors: Professor Ernst Wolvetang
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2020
Doctor Philosophy
A pre-clinical trial using bio-material-based delivery of in vitro-derived mesenchymal stem cells to effect cartilage repair in a canine model of osteoarthritis
Principal Advisor
Other advisors: Professor Ernst Wolvetang
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2018
Doctor Philosophy
Multi-matrix endocrine analysis of cetaceans: Development and examination of reproductive and adrenal monitoring techniques
Associate Advisor
Other advisors: Associate Professor Rebecca Dunlop
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2018
Doctor Philosophy
Improving Efficiency of Embryo Technologies to Expedite Livestock Genetic Gain
Associate Advisor
-
2016
Doctor Philosophy
CRISPR/Cas9-mediated traceless gene correction and activation of the HBB locus in iPSCs with the beta thalassaemia mutation
Associate Advisor
Other advisors: Professor Ernst Wolvetang
Media
Enquiries
Contact Associate Professor Deanne Whitworth directly for media enquiries about:
- regenerative medicine
- stem cells
- stem cells in animals
- use of stem cells in veterinary medicine
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