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2025

Journal Article

A heparan sulfate mimetic RAFT copolymer inhibits SARS-CoV-2 infection and ameliorates viral-induced inflammation

Ling, Jiaxin, Lundkvist, Åke, Guerrini, Marco, Ferro, Vito, Li, Jin-Ping and Li, Jinlin (2025). A heparan sulfate mimetic RAFT copolymer inhibits SARS-CoV-2 infection and ameliorates viral-induced inflammation. Advanced Science, 12 (6) 2411737, e2411737. doi: 10.1002/advs.202411737

A heparan sulfate mimetic RAFT copolymer inhibits SARS-CoV-2 infection and ameliorates viral-induced inflammation

2025

Journal Article

Synthetic glycol-split heparin tri- and tetrasaccharides provide new insights into structural peculiarities for antiheparanase activity

Ni, Minghong, Parafioriti, Michela, Esposito, Emiliano, Danzi, Margherita, Cano, Ornela, Muzi, Laura, Kayal, Yasmin, Ferro, Vito, Vlodavsky, Israel, Elli, Stefano, Naggi, Annamaria, Petitou, Maurice and Guerrini, Marco (2025). Synthetic glycol-split heparin tri- and tetrasaccharides provide new insights into structural peculiarities for antiheparanase activity. Bioorganic and Medicinal Chemistry, 118 118052, 1-13. doi: 10.1016/j.bmc.2024.118052

Synthetic glycol-split heparin tri- and tetrasaccharides provide new insights into structural peculiarities for antiheparanase activity

2024

Journal Article

Synthetic access to l-guluronic acid via fluorine-directed C-5 epimerization

See, Nicholas W., Wimmer, Norbert, Zhang, Guoqing, Krenske, Elizabeth H. and Ferro, Vito (2024). Synthetic access to l-guluronic acid via fluorine-directed C-5 epimerization. The Journal of Organic Chemistry, 89 (24), 17941-17949. doi: 10.1021/acs.joc.4c01257

Synthetic access to l-guluronic acid via fluorine-directed C-5 epimerization

2024

Journal Article

Synthesis of a deuterated disaccharide internal standard for LC-MS/MS quantitation of heparan sulfate in biological samples

Pan, Yuchen, He, Qi Qi, Wimmer, Norbert and Ferro, Vito (2024). Synthesis of a deuterated disaccharide internal standard for LC-MS/MS quantitation of heparan sulfate in biological samples. Carbohydrate Research, 545 109270, 1-8. doi: 10.1016/j.carres.2024.109270

Synthesis of a deuterated disaccharide internal standard for LC-MS/MS quantitation of heparan sulfate in biological samples

2024

Journal Article

Au‐NHC complexes with thiocarboxylate ligands: synthesis, structure, stability, thiol exchange and in vitro anti‐cancer activity

Al‐Buthabhak, Hawraa S., Falasca, Valerio, Yu, Yu, Sobolev, Alexandre N., Skelton, Brian W., Moggach, Stephen A., Ferro, Vito, Al‐Salami, Hani and Baker, Murray V. (2024). Au‐NHC complexes with thiocarboxylate ligands: synthesis, structure, stability, thiol exchange and in vitro anti‐cancer activity. Applied Organometallic Chemistry, 38 (10) e6645. doi: 10.1002/aoc.6645

Au‐NHC complexes with thiocarboxylate ligands: synthesis, structure, stability, thiol exchange and in vitro anti‐cancer activity

2024

Journal Article

Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside

See, Nicholas W., Roseli, Ras Baizureen, Wimmer, Norbert, Le, Tri T., Krenske, Elizabeth H. and Ferro, Vito (2024). Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside. Chemistry – A European Journal, 30 (52) e202400331, e202400331. doi: 10.1002/chem.202400331

Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside

2024

Journal Article

Sulfated alginate for biomedical applications

Mutch, Alexandra L., Yang, Jiankun, Ferro, Vito, A., Anitha and Grøndahl, Lisbeth (2024). Sulfated alginate for biomedical applications. Macromolecular Bioscience, 24 (11) 2400237, e2400237. doi: 10.1002/mabi.202400237

Sulfated alginate for biomedical applications

2024

Journal Article

Amphiphilic heparinoids as potent antiviral agents against SARS-CoV-2

Chhabra, Mohit, Shanthamurthy, Chethan D., Kumar, Nanjudaswamy Vijendra, Mardhekar, Sandhya, Vishweshwara, Sharath S., Wimmer, Norbert, Modhiran, Naphak, Watterson, Daniel, Amarilla, Alberto A., Cha, Jonathan S., Beckett, James R., De Voss, James J., Kayal, Yasmin, Vlodavsky, Israel, Dorsett, Lauren R., Smith, Raymond A. A., Gandhi, Neha S., Kikkeri, Raghavendra and Ferro, Vito (2024). Amphiphilic heparinoids as potent antiviral agents against SARS-CoV-2. Journal of Medicinal Chemistry, 67 (14), 11885-11916. doi: 10.1021/acs.jmedchem.4c00487

Amphiphilic heparinoids as potent antiviral agents against SARS-CoV-2

2024

Journal Article

Site-Selective Photobromination of O-Acetylated Carbohydrates in Benzotrifluoride

Zhang, Guoqing, See, Nicholas W., Wimmer, Norbert, Godinez, Michael J., Cameron, Scott A., Furneaux, Richard H. and Ferro, Vito (2024). Site-Selective Photobromination of O-Acetylated Carbohydrates in Benzotrifluoride. Organic Letters, 26 (28), 5956-5960. doi: 10.1021/acs.orglett.4c01898

Site-Selective Photobromination of O-Acetylated Carbohydrates in Benzotrifluoride

2024

Journal Article

Antiviral activities of heparan sulfate mimetic RAFT polymers against mosquito-borne viruses

Nahain, Abdullah Al, Li, Jinlin, Modhiran, Naphak, Watterson, Daniel, Li, Jin-ping, Ignjatovic, Vera, Monagle, Paul, Tsanaktsidis, John, Vamvounis, George and Ferro, Vito (2024). Antiviral activities of heparan sulfate mimetic RAFT polymers against mosquito-borne viruses. ACS Applied Bio Materials, 7 (5), 2862-2871. doi: 10.1021/acsabm.3c01223

Antiviral activities of heparan sulfate mimetic RAFT polymers against mosquito-borne viruses

2024

Journal Article

Synthesis of sulfated alginate from its tributylammonium salt: Comparing the sulfating agents H2SO4-DCC and SO3·py

Mutch, Alexandra L., Ferro, Vito, A, Anitha and Grøndahl, Lisbeth (2024). Synthesis of sulfated alginate from its tributylammonium salt: Comparing the sulfating agents H2SO4-DCC and SO3·py. Carbohydrate Polymers, 324 121488, 1-9. doi: 10.1016/j.carbpol.2023.121488

Synthesis of sulfated alginate from its tributylammonium salt: Comparing the sulfating agents H2SO4-DCC and SO3·py

2023

Journal Article

Identification of a pentasaccharide lead compound with high affinity to the SARS-CoV-2 spike protein via in silico screening

Li, Binjie, Zhang, Tianji, Cao, Hui, Ferro, Vito, Li, Jinping and Yu, Mingjia (2023). Identification of a pentasaccharide lead compound with high affinity to the SARS-CoV-2 spike protein via in silico screening. International Journal of Molecular Sciences, 24 (22) 16115, 1-16. doi: 10.3390/ijms242216115

Identification of a pentasaccharide lead compound with high affinity to the SARS-CoV-2 spike protein via in silico screening

2023

Journal Article

C-5 epimerisation of D-mannopyranosyl fluorides: the influence of anomeric configuration on radical reactivity

See, Nicholas W., Pierens, Gregory K., Krenske, Elizabeth and Ferro, Vito (2023). C-5 epimerisation of D-mannopyranosyl fluorides: the influence of anomeric configuration on radical reactivity. Synthesis, 56 (06), 966-974. doi: 10.1055/a-2149-4586

C-5 epimerisation of D-mannopyranosyl fluorides: the influence of anomeric configuration on radical reactivity

2023

Journal Article

Siderophore conjugates to combat antibiotic-resistant bacteria

Rayner, Beth, Verderosa, Anthony D., Ferro, Vito and Blaskovich, Mark A. T. (2023). Siderophore conjugates to combat antibiotic-resistant bacteria. RSC Medicinal Chemistry, 14 (5), 800-822. doi: 10.1039/d2md00465h

Siderophore conjugates to combat antibiotic-resistant bacteria

2023

Journal Article

Synthesis of uronic acid 1‐Azasugars as putative inhibitors of α‐Iduronidase, β‐glucuronidase and heparanase

Doherty, Gareth G., Ler, Geraldine Jia Ming, Wimmer, Norbert, Bernhardt, Paul V., Ashmus, Roger A., Vocadlo, David J., Armstrong, Zach W. B., Davies, Gideon J., Maccarana, Marco, Li, Jin-ping, Kayal, Yasmin and Ferro, Vito (2023). Synthesis of uronic acid 1‐Azasugars as putative inhibitors of α‐Iduronidase, β‐glucuronidase and heparanase. ChemBioChem, 24 (4) e202200619, 1-7. doi: 10.1002/cbic.202200619

Synthesis of uronic acid 1‐Azasugars as putative inhibitors of α‐Iduronidase, β‐glucuronidase and heparanase

2023

Conference Publication

A prohibitin-targeting drug modifies aspects of disease in a mouse model of Sanfilippo syndrome

Hemsley, Kim M., Beard, Helen, Doherty, Gareth G., Mubarokah, Siti, Nazri, Nazzmer and Ferro, Vito (2023). A prohibitin-targeting drug modifies aspects of disease in a mouse model of Sanfilippo syndrome. WORLDSymposiumTM 2023 19th Annual Research Meeting & Scientific Sessions, Orlando, FL United States, 22 - 26 February 2023. Waltham, MA United States: Academic Press. doi: 10.1016/j.ymgme.2022.107145

A prohibitin-targeting drug modifies aspects of disease in a mouse model of Sanfilippo syndrome

2023

Journal Article

Synthesis of a Gal-β-(1→4)-Gal disaccharide as a ligand for the fimbrial adhesin UcaD

Boittier, Eric D., Wimmer, Norbert, Harris, Alexandria K., Schembri, Mark A. and Ferro, Vito (2023). Synthesis of a Gal-β-(1→4)-Gal disaccharide as a ligand for the fimbrial adhesin UcaD. Australian Journal of Chemistry, 76 (1), 30-36. doi: 10.1071/ch22158

Synthesis of a Gal-β-(1→4)-Gal disaccharide as a ligand for the fimbrial adhesin UcaD

2023

Book Chapter

An enzymatic activity assay for heparanase that is useful for evaluating clinically relevant inhibitors and studying kinetics

Hammond, Edward and Ferro, Vito (2023). An enzymatic activity assay for heparanase that is useful for evaluating clinically relevant inhibitors and studying kinetics. Methods in molecular biology. (pp. 227-238) edited by Nikos K. Karamanos. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-2946-8_16

An enzymatic activity assay for heparanase that is useful for evaluating clinically relevant inhibitors and studying kinetics

2022

Journal Article

Evidence for multiple binding modes in the initial contact between SARS‐CoV‐2 spike S1 protein and cell surface glycans**

Parafioriti, Michela, Ni, Minghong, Petitou, Maurice, Mycroft‐West, Courtney J., Rudd, Timothy R., Gandhi, Neha S., Ferro, Vito, Turnbull, Jeremy E., Lima, Marcelo A., Skidmore, Mark A., Fernig, David G., Yates, Edwin A., Bisio, Antonella, Guerrini, Marco and Elli, Stefano (2022). Evidence for multiple binding modes in the initial contact between SARS‐CoV‐2 spike S1 protein and cell surface glycans**. Chemistry – A European Journal, 29 (1) e202202599, e202202599. doi: 10.1002/chem.202202599

Evidence for multiple binding modes in the initial contact between SARS‐CoV‐2 spike S1 protein and cell surface glycans**

2022

Journal Article

An improved protocol for the stereoselective synthesis of β-D-glycosyl fluorides from 2-O-acyl thioglycosides

See, Nicholas W, Xu, Xiaowen and Ferro, Vito (2022). An improved protocol for the stereoselective synthesis of β-D-glycosyl fluorides from 2-O-acyl thioglycosides. The Journal of Organic Chemistry, 87 (21), 14230-14240. doi: 10.1021/acs.joc.2c01748

An improved protocol for the stereoselective synthesis of β-D-glycosyl fluorides from 2-O-acyl thioglycosides