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2012 Journal Article Potent anti-respiratory syncytial virus activity of a cholestanol-sulfated tetrasaccharide conjugateLundin, Anna, Bergstrom, Tomas, Andrighetti-Fröhner, Carla R., Bendrioua, Loubna, Ferro, Vito and Trybala, Edward (2012). Potent anti-respiratory syncytial virus activity of a cholestanol-sulfated tetrasaccharide conjugate. Antiviral Research, 93 (1), 101-109. doi: 10.1016/j.antiviral.2011.11.002 |
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2011 Journal Article PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical modelsDredge, K, Hammond, E, Handley, P, Gonda, TJ, Smith, MT, Vincent, C, Brandt, R, Ferro, V and Bytheway, I (2011). PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models. British Journal of Cancer, 104 (5), 635-642. doi: 10.1038/bjc.2011.11 |
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2011 Journal Article Synthesis of simple heparanase substratesPearson, Andrew G., Kiefel, Milton J., Ferro, Vito and von Itzstein, Mark (2011). Synthesis of simple heparanase substrates. Organic and Biomolecular Chemistry, 9 (12), 4614-4625. doi: 10.1039/c1ob05165b |
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2010 Journal Article Lipophile-conjugated sulfated oligosaccharides as novel microbicides against HIV-1Said, J, Trybala, E, Andersson, E, Johnstone, K, Liu, LG, Wimmer, N, Ferro, V and Bergstrom, T (2010). Lipophile-conjugated sulfated oligosaccharides as novel microbicides against HIV-1. Antiviral Research, 86 (3), 286-295. doi: 10.1016/j.antiviral.2010.03.011 |
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2010 Journal Article The PG500 series: Novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapyDredge, K., Hammond, E., Davis, K., Li, C. P., Liu, L., Johnstone, K., Handley, P., Wimmer, N., Gonda, T. J., Gautam, A., Ferro, V. and Bytheway, I. (2010). The PG500 series: Novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy. Investigational New Drugs, 28 (3), 276-283. doi: 10.1007/s10637-009-9245-5 |
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2010 Journal Article A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virusEkblad, M, Adamiak, B, Bergstrom, T, Johnstone, KD, Karoli, T, Liu, LG, Ferro, V and Trybala, E (2010). A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virus. Antiviral Research, 86 (2), 196-203. doi: 10.1016/j.antiviral.2010.02.318 |
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2010 Journal Article Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growthJohnstone, Ken D., Karoli, Tomislav, Liu, Ligong, Dredge, Keith, Copeman, Elizabeth, Li, Cai Ping, Davis, Kat, Hammond, Edward, Bytheway, Ian, Kostewicz, Edmund, Chiu, Francis C. K., Shackleford, David M., Charman, Susan A., Charman, William N., Harenberg, Job, Gonda, Thomas J. and Ferro, Vito (2010). Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth. Journal of Medicinal Chemistry, 53 (4), 1686-1699. doi: 10.1021/jm901449m |
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2010 Journal Article Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screeningHammond, Edward, Li, Cai Ping and Ferro, Vito (2010). Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screening. Analytical Biochemistry, 396 (396), 112-116. doi: 10.1016/j.ab.2009.09.007 |
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2009 Journal Article Synthesis of a heparan sulfate mimetic disaccharide with a conformationally locked residue from a common intermediateFairweather, J.K., Karoli, T., Liu, L., Bytheway, I. and Ferro, V. (2009). Synthesis of a heparan sulfate mimetic disaccharide with a conformationally locked residue from a common intermediate. Carbohydrate Research, 344 (17), 2394-2398. doi: 10.1016/j.carres.2009.09.012 |
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2009 Journal Article A surface plasmon resonance-based solution affinity assay for heparan sulfate-binding proteinsCochran, S., Ping Li, C. and Ferro, V. (2009). A surface plasmon resonance-based solution affinity assay for heparan sulfate-binding proteins. Glycoconjugate Journal, 26 (5), 577-587. doi: 10.1007/s10719-008-9210-0 |
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2009 Other Outputs Novel sulfated oligosaccharide derivativesFerro, V., Karoli, T., Liu, L., Handley, P.N., Johnstone, K.D., Wimmer, N. and Hammond, E.T. (2009). Novel sulfated oligosaccharide derivatives. WO/2009/049370. |
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2009 Journal Article An improved synthetic route to the potent angiogenesis inhibitor benzyl manα(1→3)-Manα(1→3)-Manα(1→3) -Manα(1→2)-Man HexadecasulfateLiu, LG, Johnstone, KD, Fairweather, JK, Dredge, K and Ferro, V (2009). An improved synthetic route to the potent angiogenesis inhibitor benzyl manα(1→3)-Manα(1→3)-Manα(1→3) -Manα(1→2)-Man Hexadecasulfate. Australian Journal of Chemistry, 62 (6), 546-552. doi: 10.1071/CH09015 |
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2008 Journal Article Synthesis and heparanase inhibitory activity of sulfated mannooligosaccharides related to the antiangiogenic agent PI-88Fairweather, J.K., Hammond, E., Johnstone, K.D. and Ferro, V. (2008). Synthesis and heparanase inhibitory activity of sulfated mannooligosaccharides related to the antiangiogenic agent PI-88. Bioorganic & Medicinal Chemistry, 16 (2), 699-709. doi: 10.1016/j.bmc.2007.10.044 |
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2008 Journal Article Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharidesLiu, Ligong, Bytheway, Ian, Karoli, Tomislav, Fairweather, Jon K., Cochran, Siska, Li, Caiping and Ferro, Vito (2008). Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides. Bioorganic & Medicinal Chemistry Letters, 18 (1), 344-349. doi: 10.1016/j.bmcl.2007.10.071 |
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2007 Journal Article Herpes simplex virus type 2 glycoprotein G is targeted by the sulfated oligo- and polysaccharide inhibitors of virus attachment to cellsAdamiak, Beata, Ekblad, Maria, Bergström, Tomas, Ferro, Vito and Trybala, Edward (2007). Herpes simplex virus type 2 glycoprotein G is targeted by the sulfated oligo- and polysaccharide inhibitors of virus attachment to cells. Journal of Virology, 81 (24), 13424-13434. doi: 10.1128/JVI.01528-07 |
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2007 Journal Article Molecular basis for resistance of herpes simplex virus type 1 mutants to the sulfated oligosaccharide inhibitor PI-88Ekblad, Maria, Adamiak, Beata, Bergefall, Kicki, Nenonen, Hannah, Roth, Anette, Bergstrom, Tomas, Ferro, Vito and Trybala, Edward (2007). Molecular basis for resistance of herpes simplex virus type 1 mutants to the sulfated oligosaccharide inhibitor PI-88. Virology, 367 (2), 244-252. doi: 10.1016/j.virol.2007.05.040 |
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2007 Journal Article PI-88 and novel heparan sulfate mimetics inhibit angiogenesisFerro, Vito, Dredge, Keith, Liu, Ligong, Hammond, Edward, Bytheway, Ian, Li, Caiping, Johnstone, Ken, Karoli, Tomislav, Davis, Kat, Copeman, Elizabeth and Gautam, Anand: (2007). PI-88 and novel heparan sulfate mimetics inhibit angiogenesis. Seminars in Thrombosis and Hemostasis, 33 (5), 557-562. doi: 10.1055/s-2007-982088 |
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2007 Journal Article Enantiospecific synthesis of the heparanase inhibitor (+)-trachyspic acid and stereoisomers from a common precursorZammit, S. C., Ferro, V., Hammond, E. and Rizzacasa, M. A. (2007). Enantiospecific synthesis of the heparanase inhibitor (+)-trachyspic acid and stereoisomers from a common precursor. Organic and Biomolecular Chemistry, 5 (17), 2826-2834. doi: 10.1039/b708594j |
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2007 Conference Publication Heparan sulfate mimetics - potent angiogenesis inhibitors for cancer therapyDredge, K, Davis, K, Liu, L, Johnstone, K, Handley, P, Wimmer, N, Bytheway, I, Hammond, E, Li, CP, Rowley, J, Ferro, V and Gautam, A (2007). Heparan sulfate mimetics - potent angiogenesis inhibitors for cancer therapy. AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, San Francisco, CA, United States, 22-26 October 2007. Philadelphia, PA, United States: American Association for Cancer Research. |
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2007 Journal Article Molecular basis for resistance of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.Ekblad, M., Adamiak, B., Bergefall, K., Nenonen, H., Roth, A., Bergstrom, T, Ferro, V. and Trybala, E. (2007). Molecular basis for resistance of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.. Virology (367), 244-252. |
