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2017 Journal Article Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growthChua, Ming Jang, Arnold, Megan S. J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Spath, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S. and Andrews, Katherine T. (2017). Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth. International Journal for Parasitology: Drugs and Drug Resistance, 7 (1), 42-50. doi: 10.1016/j.ijpddr.2016.12.005 |
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2017 Journal Article Mapping transmembrane residues of proteinase activated recpetor 2 (PAR2) that influence ligand-modulated calcium signalingSuen, J.Y., Adams, M. N., Lim, J., Madala, P.K., Xu, W, Cotterell, A., He, Y., Yua, Mei-Kwan, Hooper, J. D. and Fairlie, D.P. (2017). Mapping transmembrane residues of proteinase activated recpetor 2 (PAR2) that influence ligand-modulated calcium signaling. Pharmacological Research, 117, 328-342. doi: 10.1016/j.phrs.2016.12.020 |
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2017 Journal Article Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cellsKeller, Andrew N., Eckle, Sidonia B. G., Xu, Weijun, Liu, Ligong, Hughes, Victoria A., Mak, Jeffrey Y. W., Meehan, Bronwyn S., Pediongco, Troi, Birkinshaw, Richard W., Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Kjer-Nielsen, Lars, Gherardin, Nicholas A., Godfrey, Dale I., Kostenko, Lyudmila, Corbett, Alexandra J., Purcell, Anthony W., Fairlie, David P., McCluskey, James and Rossjohn, Jamie (2017). Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology, 18 (4), 402-411. doi: 10.1038/ni.3679 |
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2017 Journal Article Histone deacetylases (HDAC) in physiological and pathological bone remodellingCantley, M. D., Zannettino, A. C. W., Bartold, P. M., Fairlie, D. P. and Haynes, D. R. (2017). Histone deacetylases (HDAC) in physiological and pathological bone remodelling. Bone, 95, 162-174. doi: 10.1016/j.bone.2016.11.028 |
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2017 Journal Article Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signalingPlisson, Fabien, Hill, Timothy A., Mitchell, Justin M., Hoang, Huy N., de Araujo, Aline D., Xu, Weijun, Cotterell, Adam, Edmonds, David J., Stanton, Robert V., Derksen, David R., Loria, Paula M., Griffith, David A., Price, David A., Liras, Spiros and Fairlie, David P. (2017). Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling. European Journal of Medicinal Chemistry, 127, 703-714. doi: 10.1016/j.ejmech.2016.10.044 |
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2017 Journal Article Alpha helix nucleation by a simple cyclic tetrapeptideHoang, Huy N., Wu, Chongyang, Beyer, Renee L., Hill, Timothy A. and Fairlie, David P. (2017). Alpha helix nucleation by a simple cyclic tetrapeptide. Australian Journal of Chemistry, 70 (2), 213-219. doi: 10.1071/CH16591 |
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2017 Conference Publication Activity of the histone deacetylase (HDAC) inhibitor AR-42 in a murine malaria modelChua, Ming Jang, Do, Darren, Bachu, Prabhakar, Reid, Robert, Fairlie, David, Skinner-Adams, Tina and Andrews, Kathy (2017). Activity of the histone deacetylase (HDAC) inhibitor AR-42 in a murine malaria model. 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), Baltimore, MD United States, 5-09 November 2017. Deerfield, IL United States: American Society of Tropical Medicine and Hygiene. |
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2017 Conference Publication Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritisJansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Koppejan, Hester, Hameetman, Marjolijn, Liu, Ligong, Corbett, Alexandra, Eckle, Sidonia, Fairlie, David, Toes, Rene E. M., van Gaalen, Floris, Rossjohn, Jamie, McCluskey, James and Thomas, Ranjeny (2017). Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis. 2017 ACR/ARHP Annual Meeting, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons. |
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2017 Book Chapter Thiazoles in peptides and peptidomimeticsMak, Jeffrey Y. W., Xu, Weijun and Fairlie, David P. (2017). Thiazoles in peptides and peptidomimetics. Peptidomimetics I. (pp. 235-266) edited by William D. Lubell. Cham, Switzerland: Springer. doi: 10.1007/7081_2015_176 |
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2017 Journal Article Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signalChen, Z., Wang, H., D'Souza, C., Sun, S., Kostenko, L., Eckle, S. B. G, Meehan, B. S., Jackson, D.C., Strugnell, R. A., Cao, H., Wang, N., Fairlie, David, Liu, L., Godfrey, D. I., Rossjohn, J., McCluskey, J. and Corbett, A. J. (2017). Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signal. Mucosal Immunology, 10 (1), 58-68. doi: 10.1038/mi.2016.39 |
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2017 Journal Article Total synthesis of the Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognitionCheng, Janice, Liu, Ligong, Pellicci, Daniel, Reddiex, Scott J.J., Cotton, Rachel, Cheng, Tan-Yun, Young, David, Van Rhijn, Ildiko, Moody, Branch, Rossjohn, Jamie, Fairlie, David, Godfrey, Dale and Williams, Spencer John (2017). Total synthesis of the Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognition. Chemistry - A European Journal, 23 (7), 1694-1701. doi: 10.1002/chem.201605287 |
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2017 Conference Publication Vitamin B2 related molecules that activate T cellsMak, Jeffrey, Xu, Weijun, Reid, Robert, Corbett, Alexandra, Meehan, Bronwyn, Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie, McCluskey, James, Liu, Ligong and Fairlie, David (2017). Vitamin B2 related molecules that activate T cells. 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Washington DC, USA, 20-24 August 2017. Washington DC, USA: American Chemical Society. |
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2017 Journal Article An HDAC6 inhibitor confers protection and selectively inhibits B-cell infiltration in DSS-induced colitis in miceDo, Anh, Reid, Robert C., Lohman, Rink-Jan, Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2017). An HDAC6 inhibitor confers protection and selectively inhibits B-cell infiltration in DSS-induced colitis in mice. The Journal of Pharmacology and Experimental Therapeutics, 360 (1), 140-151. doi: 10.1124/jpet.116.236711 |
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2016 Journal Article Product release is rate-limiting for catalytic processing by the Dengue virus proteaseShannon, A. E., Pedroso, M. M., Chappell, K. J., Watterson, D., Liebscher, S., Kok, W. M., Fairlie, D. P., Schenk, G. and Young, P. R. (2016). Product release is rate-limiting for catalytic processing by the Dengue virus protease. Scientific Reports, 6 (1) 37539, 37539. doi: 10.1038/srep37539 |
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2016 Journal Article Correction: Downsizing the BAD BH3 peptide to small constrained alpha-helices with improved ligand efficiency (vol 14, pg 10939, 2016)Shepherd, Nicholas E., Harrison, Rosemary S., Ruiz-Gomez, Gloria, Abbenante, Giovanni, Mason, Jody M. and Fairlie, David P. (2016). Correction: Downsizing the BAD BH3 peptide to small constrained alpha-helices with improved ligand efficiency (vol 14, pg 10939, 2016). Organic & Biomolecular Chemistry, 14 (48), 11525-11525. doi: 10.1039/c6ob90178f |
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2016 Journal Article Downsizing the BAD BH3 peptide to small contrained alpha-helices with improved ligand efficiencyShepherd, Nicholas E., Harrison, Rosemary S., Ruiz-Gomez, Gloria, Abbenante, Giovanni, Mason, Jody M. and Fairlie, David P. (2016). Downsizing the BAD BH3 peptide to small contrained alpha-helices with improved ligand efficiency. Organic and Biomolecular Chemistry, 46 (14), 10939-10945. doi: 10.1039/C6OB02185A |
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2016 Journal Article A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineageKoay, Hui-Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Mackay, Laura K., Almeida, Catarina F., Russ, Brendan E., Nold-Petry, Claudia A., Nold, Marcel F., Bedoui, Sammy, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Sidonia B. G., Meehan, Bronwyn, D'Udekem, Yves, Konstantinov, Igor E., Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie, Chong, Mark M., Kedzierska, Katherine, Berzins, Stuart P., Belz, Gabrielle T., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Pellicci, Daniel G. (2016). A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology, 17 (11), 1300-1311. doi: 10.1038/ni.3565 |
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2016 Journal Article Review stapling peptides using cysteine crosslinkingFairlie, David P. and Dantas de Araujo, Aline (2016). Review stapling peptides using cysteine crosslinking. Biopolymers, 106 (6), 843-852. doi: 10.1002/bip.22877 |
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2016 Conference Publication Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing SpondylitisJansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Benham, Helen, Cummins, Lisa, Brown, Matthew, Kenna, Tony, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Morrison, Mark, Thomas, Ranjeny, Cuiv, Paraic O., McCluskey, James and Corbett, Alexandra (2016). Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis. 2016 ACR/ARHP Annual Meeting, Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.39977 |
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2016 Journal Article Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activationLoh, Liyen, Wang, Zhongfang, Sant, Sneha, Koutsakos, Marios, Jegaskanda, Sinthujan, Corbett, Alexandra J., Liu, Ligong, Fairlie, David P., Crowe, Jane, Rossjohn, Jamie, Xu, Jianqing, Doherty, Peter C., McCluskey, James and Kedzierska, Katherine (2016). Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation. Proceedings of the National Academy of Sciences, 113 (36), 10133-10138. doi: 10.1073/pnas.1610750113 |
