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2018 Conference Publication PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidneyHan, Y., Ma, F., Ozols, E., Chew, P., Vesey, D., Gobe, G., Morais, C., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2018). PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8–12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13441 |
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2018 Conference Publication Stereoelectronic effects on dienophile separation influence the Diels–Alder synthesis of molecular cleftsStoermer, Martin J., Wickramasinghe, Wasantha A., Byriel, Karl A., Hockless, David C. R., Skelton, Brian W., Sobolev, Alexandre N., White, Alan H., Mak, Jeffrey Y. W. and Fairlie, David P. (2018). Stereoelectronic effects on dienophile separation influence the Diels–Alder synthesis of molecular clefts. 2018 Royal Society of Chemistry Twitter Conference, London, United Kingdom (held online), 6-7 March 2018. London, United Kingdom: Royal Society of Chemistry. |
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2018 Conference Publication RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver diseaseRamnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018). RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. International Liver Congress (ILC), Paris, France, 11-15 April, 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(18)31040-7 |
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2018 Journal Article Chemical approaches to modulating complement-mediated diseasesIyer, Abishek, Xu, Weijun, Reid, Robert C and Fairlie, David P (2018). Chemical approaches to modulating complement-mediated diseases. Journal of Medicinal Chemistry, 61 (8), 3253-3276. doi: 10.1021/acs.jmedchem.7b00882 |
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2017 Journal Article Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular CleftsStoermer, Martin J., Wickramasinghe, Wasantha A., Byriel, Karl A., Hockless, David C. R., Skelton, Brian W., Sobolev, Alexandre N., White, Allan H., Mak, Jeffrey Y. W. and Fairlie, David P. (2017). Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular Clefts. European Journal of Organic Chemistry, 2017 (45), 6793-6796. doi: 10.1002/ejoc.201701319 |
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2017 Journal Article Protease activated receptor 2 controls myelin development, resiliency and repairYoon, Hyesook, Radulovic, Maja, Walters, Grant, Paulsen, Alex R., Drucker, Kristen, Starski, Phillip, Wu, Jianmin, Fairlie, David P. and Scarisbrick, Isobel A. (2017). Protease activated receptor 2 controls myelin development, resiliency and repair. GLIA, 65 (12), 2070-2086. doi: 10.1002/glia.23215 |
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2017 Journal Article Downsizing proto-oncogene cFos to short helix-constrained peptides that bind JunBaxter, Daniel, Perry, Samuel R., Hill, Timothy A., Kok, W. Mei, Zaccai, Nathan R., Brady, R. Leo, Fairlie, David P. and Mason, Jody M. (2017). Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun. ACS Chemical Biology, 12 (8), 2051-2061. doi: 10.1021/acschembio.7b00303 |
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2017 Journal Article Quinazolinone derivatives as inhibitors of homologous recombinase RAD51Ward, Ambber, Dong, Lilong, Harris, Jonathan M., Khanna, Kum Kum, Al-Ejeh, Fares, Fairlie, David P., Wiegmans, Adrian P. and Liu, Ligong (2017). Quinazolinone derivatives as inhibitors of homologous recombinase RAD51. Bioorganic and Medicinal Chemistry Letters, 27 (14), 3096-3100. doi: 10.1016/j.bmcl.2017.05.039 |
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2017 Journal Article Orally absorbed cyclic peptidesNielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2017). Orally absorbed cyclic peptides. Chemical Reviews, 117 (12), 8094-8128. doi: 10.1021/acs.chemrev.6b00838 |
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2017 Journal Article Europium-labeled synthetic C3a protein as a novel fluorescent probe for human complement C3a receptorDantas de Araujo, Aline, Wu, Chongyang, Wu, Kai-Chen, Reid, Robert C., Durek, Thomas, Lim, Junxian and Fairlie, David P. (2017). Europium-labeled synthetic C3a protein as a novel fluorescent probe for human complement C3a receptor. Bioconjugate Chemistry, 28 (6), 1669-1676. doi: 10.1021/acs.bioconjchem.7b00132 |
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2017 Journal Article Biased signaling by agonists of protease activated receptor 2Jiang, Yuhong, Yau, Mei-Kwan, Kok, W. Mei, Lim, Junxian, Wu, Kai-Chen, Liu, Ligong, Hill, Timothy A., Suen, Jacky Y. and Fairlie, David P. (2017). Biased signaling by agonists of protease activated receptor 2. ACS Chemical Biology, 12 (5), 1217-1226. doi: 10.1021/acschembio.6b01088 |
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2017 Journal Article Tolyporphin macrocycles from the cyanobacterium Tolypothrix nodosa selectively bind copper and silver and reverse multidrug resistancePrinsep, Michele R., Appleton, Trevor G., Hanson, Graeme R., Lane, Ian, Smith, Charles D., Puddick, Jonathan and Fairlie, David P. (2017). Tolyporphin macrocycles from the cyanobacterium Tolypothrix nodosa selectively bind copper and silver and reverse multidrug resistance. Inorganic Chemistry, 56 (10), 5577-5585. doi: 10.1021/acs.inorgchem.6b03000 |
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2017 Journal Article Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprinaBagnall, Neil H., Hines, Barney M., Lucke, Andrew J., Gupta, Praveer K., Reid, Robert C., Fairlie, David P. and Kotze, Andrew C. (2017). Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprina. International Journal for Parasitology: Drugs and Drug Resistance, 7 (1), 51-60. doi: 10.1016/j.ijpddr.2017.01.001 |
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2017 Journal Article The ribosomal protein S19 suppresses antitumor immune responses via the complement C5a receptor 1Markiewski, Maciej M., Vadrevu, Surya Kumari, Sharma, Sharad K., Chintala, Navin Kumar, Ghouse, Shanawaz, Cho, Jun-Hung, Fairlie, David P., Paterson, Yvonne, Astrinidis, Aristotelis and Karbowniczek, Magdalena (2017). The ribosomal protein S19 suppresses antitumor immune responses via the complement C5a receptor 1. Journal of Immunology, 198 (7), 2989-2999. doi: 10.4049/jimmunol.1602057 |
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2017 Journal Article Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growthChua, Ming Jang, Arnold, Megan S. J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Spath, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S. and Andrews, Katherine T. (2017). Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth. International Journal for Parasitology: Drugs and Drug Resistance, 7 (1), 42-50. doi: 10.1016/j.ijpddr.2016.12.005 |
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2017 Journal Article Mapping transmembrane residues of proteinase activated recpetor 2 (PAR2) that influence ligand-modulated calcium signalingSuen, J.Y., Adams, M. N., Lim, J., Madala, P.K., Xu, W, Cotterell, A., He, Y., Yua, Mei-Kwan, Hooper, J. D. and Fairlie, D.P. (2017). Mapping transmembrane residues of proteinase activated recpetor 2 (PAR2) that influence ligand-modulated calcium signaling. Pharmacological Research, 117, 328-342. doi: 10.1016/j.phrs.2016.12.020 |
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2017 Journal Article Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cellsKeller, Andrew N., Eckle, Sidonia B. G., Xu, Weijun, Liu, Ligong, Hughes, Victoria A., Mak, Jeffrey Y. W., Meehan, Bronwyn S., Pediongco, Troi, Birkinshaw, Richard W., Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Kjer-Nielsen, Lars, Gherardin, Nicholas A., Godfrey, Dale I., Kostenko, Lyudmila, Corbett, Alexandra J., Purcell, Anthony W., Fairlie, David P., McCluskey, James and Rossjohn, Jamie (2017). Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology, 18 (4), 402-411. doi: 10.1038/ni.3679 |
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2017 Journal Article Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signalingPlisson, Fabien, Hill, Timothy A., Mitchell, Justin M., Hoang, Huy N., de Araujo, Aline D., Xu, Weijun, Cotterell, Adam, Edmonds, David J., Stanton, Robert V., Derksen, David R., Loria, Paula M., Griffith, David A., Price, David A., Liras, Spiros and Fairlie, David P. (2017). Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling. European Journal of Medicinal Chemistry, 127, 703-714. doi: 10.1016/j.ejmech.2016.10.044 |
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2017 Journal Article Alpha helix nucleation by a simple cyclic tetrapeptideHoang, Huy N., Wu, Chongyang, Beyer, Renee L., Hill, Timothy A. and Fairlie, David P. (2017). Alpha helix nucleation by a simple cyclic tetrapeptide. Australian Journal of Chemistry, 70 (2), 213-219. doi: 10.1071/CH16591 |
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2017 Journal Article Histone deacetylases (HDAC) in physiological and pathological bone remodellingCantley, M. D., Zannettino, A. C. W., Bartold, P. M., Fairlie, D. P. and Haynes, D. R. (2017). Histone deacetylases (HDAC) in physiological and pathological bone remodelling. Bone, 95, 162-174. doi: 10.1016/j.bone.2016.11.028 |
