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2018 Journal Article Recipient mucosal-associated invariant T cells control GVHD within the colonVarelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646 |
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2018 Journal Article Lysine deacetylases and regulated glycolysis in macrophagesShakespear, Melanie R., Iyer, Abishek, Cheng, Catherine Youting, Das Gupta, Kaustav, Singhal, Amit, Fairlie, David P. and Sweet, Matthew J. (2018). Lysine deacetylases and regulated glycolysis in macrophages. Trends in Immunology, 39 (6), 473-488. doi: 10.1016/j.it.2018.02.009 |
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2018 Journal Article Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myelomaGherardin, Nicholas A, Loh, Liyen, Admojo, Lorenztino, Davenport, Alexander J, Richardson, Kelden, Rogers, Amy, Darcy, Phillip K, Jenkins, Misty R., Prince, H. Miles, Harrison, Simon J., Quach, Hang, Fairlie, David P., Kedzierska, Katherine, McCluskey, James, Uldrich, Adam P, Neeson, Paul J., Ritchie, David S. and Godfrey, Dale I. (2018). Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma. Scientific reports, 8 (1) 4159, 4159. doi: 10.1038/s41598-018-22130-1 |
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2018 Journal Article Chemically Diverse Helix-Constrained Peptides Using Selenocysteine CrosslinkingDantas de Araujo, Aline, Perry, Samuel R. and Fairlie, David P. (2018). Chemically Diverse Helix-Constrained Peptides Using Selenocysteine Crosslinking. Organic Letters, 20 (5), 1453-1456. doi: 10.1021/acs.orglett.8b00233 |
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2018 Journal Article Human blood MAIT cell subsets defined using MR1 tetramersGherardin, Nicholas A., Souter, Michael N. T., Koay, Hui-Fern, Mangas, Kirstie M., Seemann, Torsten, Stinear, Timothy P., Eckle, Sidonia B. G., Berzins, Stuart P., d'Udekem, Yves, Konstantinov, Igor E., Fairlie, David P., Ritchie, David S., Neeson, Paul J., Pellicci, Daniel G., Uldrich, Adam P., McCluskey, James and Godfrey, Dale I. (2018). Human blood MAIT cell subsets defined using MR1 tetramers. Immunology and Cell Biology, 96 (5), 507-525. doi: 10.1111/imcb.12021 |
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2018 Journal Article A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cellsJiang, Yuhong, Yau, Mei-Kwan, Lim, Junxian, Wu, Kai-Chen, Xu, Weijun, Suen, Jacky Y and Fairlie, David P (2018). A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells. The Journal of pharmacology and experimental therapeutics, 364 (2), 246-257. doi: 10.1124/jpet.117.245027 |
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2018 Journal Article Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori InfectionD'Souza, Criselle, Pediongco, Troi, Wang, Huimeng, Scheerlinck, Jean-Pierre Y., Kostenko, Lyudmila, Esterbauer, Robyn, Stent, Andrew W., Eckle, Sidonia B. G., Meehan, Bronwyn S., Strugnell, Richard A., Cao, Hanwei, Liu, Ligong, Mak, Jeffrey Y. W., Lovrecz, George, Lu, Louis, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Every, Alison L., Chen, Zhenjun and Corbett, Alexandra J. (2018). Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection. Journal of Immunology, 200 (5), 1901-1916. doi: 10.4049/jimmunol.1701512 |
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2018 Journal Article Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeabilityPerry, Samuel R, Hill, Timothy A, de Araujo, Aline D, Hoang, Huy N and Fairlie, David P (2018). Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability. Organic & biomolecular chemistry, 16 (3), 367-371. doi: 10.1039/c7ob02952g |
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2018 Conference Publication Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colonVarelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology Meeting, Austin Tx, 4-8 May 2018. Bethesda, MD United States: American Association of Immunologists. |
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2018 Conference Publication PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidneyHan, Y., Ma, F., Ozols, E., Chew, P., Vesey, D., Gobe, G., Morais, C., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2018). PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8–12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13441 |
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2018 Conference Publication Stereoelectronic effects on dienophile separation influence the Diels–Alder synthesis of molecular cleftsStoermer, Martin J., Wickramasinghe, Wasantha A., Byriel, Karl A., Hockless, David C. R., Skelton, Brian W., Sobolev, Alexandre N., White, Alan H., Mak, Jeffrey Y. W. and Fairlie, David P. (2018). Stereoelectronic effects on dienophile separation influence the Diels–Alder synthesis of molecular clefts. 2018 Royal Society of Chemistry Twitter Conference, London, United Kingdom (held online), 6-7 March 2018. London, United Kingdom: Royal Society of Chemistry. |
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2018 Journal Article Chemical approaches to modulating complement-mediated diseasesIyer, Abishek, Xu, Weijun, Reid, Robert C and Fairlie, David P (2018). Chemical approaches to modulating complement-mediated diseases. Journal of Medicinal Chemistry, 61 (8), 3253-3276. doi: 10.1021/acs.jmedchem.7b00882 |
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2018 Conference Publication RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver diseaseRamnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018). RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. International Liver Congress (ILC), Paris, France, 11-15 April, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(18)31040-7 |
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2017 Journal Article Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular CleftsStoermer, Martin J., Wickramasinghe, Wasantha A., Byriel, Karl A., Hockless, David C. R., Skelton, Brian W., Sobolev, Alexandre N., White, Allan H., Mak, Jeffrey Y. W. and Fairlie, David P. (2017). Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular Clefts. European Journal of Organic Chemistry, 2017 (45), 6793-6796. doi: 10.1002/ejoc.201701319 |
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2017 Journal Article Protease activated receptor 2 controls myelin development, resiliency and repairYoon, Hyesook, Radulovic, Maja, Walters, Grant, Paulsen, Alex R., Drucker, Kristen, Starski, Phillip, Wu, Jianmin, Fairlie, David P. and Scarisbrick, Isobel A. (2017). Protease activated receptor 2 controls myelin development, resiliency and repair. GLIA, 65 (12), 2070-2086. doi: 10.1002/glia.23215 |
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2017 Journal Article Downsizing proto-oncogene cFos to short helix-constrained peptides that bind JunBaxter, Daniel, Perry, Samuel R., Hill, Timothy A., Kok, W. Mei, Zaccai, Nathan R., Brady, R. Leo, Fairlie, David P. and Mason, Jody M. (2017). Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun. ACS Chemical Biology, 12 (8), 2051-2061. doi: 10.1021/acschembio.7b00303 |
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2017 Journal Article Quinazolinone derivatives as inhibitors of homologous recombinase RAD51Ward, Ambber, Dong, Lilong, Harris, Jonathan M., Khanna, Kum Kum, Al-Ejeh, Fares, Fairlie, David P., Wiegmans, Adrian P. and Liu, Ligong (2017). Quinazolinone derivatives as inhibitors of homologous recombinase RAD51. Bioorganic and Medicinal Chemistry Letters, 27 (14), 3096-3100. doi: 10.1016/j.bmcl.2017.05.039 |
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2017 Journal Article Orally absorbed cyclic peptidesNielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2017). Orally absorbed cyclic peptides. Chemical Reviews, 117 (12), 8094-8128. doi: 10.1021/acs.chemrev.6b00838 |
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2017 Journal Article Europium-labeled synthetic C3a protein as a novel fluorescent probe for human complement C3a receptorDantas de Araujo, Aline, Wu, Chongyang, Wu, Kai-Chen, Reid, Robert C., Durek, Thomas, Lim, Junxian and Fairlie, David P. (2017). Europium-labeled synthetic C3a protein as a novel fluorescent probe for human complement C3a receptor. Bioconjugate Chemistry, 28 (6), 1669-1676. doi: 10.1021/acs.bioconjchem.7b00132 |
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2017 Journal Article Biased signaling by agonists of protease activated receptor 2Jiang, Yuhong, Yau, Mei-Kwan, Kok, W. Mei, Lim, Junxian, Wu, Kai-Chen, Liu, Ligong, Hill, Timothy A., Suen, Jacky Y. and Fairlie, David P. (2017). Biased signaling by agonists of protease activated receptor 2. ACS Chemical Biology, 12 (5), 1217-1226. doi: 10.1021/acschembio.6b01088 |
