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2019 Journal Article Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilitiesLohman, Rink-Jan, Nielsen, Daniel S., Kok, W. Mei, Hoang, Huy N., Hill, Timothy A. and Fairlie, David P. (2019). Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities. Chemical Communications, 55 (89), 13362-13365. doi: 10.1039/c9cc06234c |
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2019 Journal Article Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cellsLer, Geraldine J. M., Xu, Weijun, Mak, Jeffrey Y. W., Liu, Ligong, Bernhardt, Paul V. and Fairlie, David P (2019). Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cells. Chemistry – A European Journal, 25 (68) chem.201903732, 15594-15608. doi: 10.1002/chem.201903732 |
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2019 Journal Article Protease-activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidneyMa, Frank Y., Han, Yingjie, Ozols, Elyce, Chew, Phyllis, Vesey, David A., Gobe, Glenda C., Morais, Christudas, Lohman, Rink-Jan, Suen, Jacky Y., Johnson, David W., Fairlie, David P. and Nikolic-Paterson, David J. (2019). Protease-activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidney. Nephrology, 24 (9) nep.13635, 983-991. doi: 10.1111/nep.13635 |
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2019 Other Outputs Modulators of protease activated receptorsFairlie, David, Liu, Ligong, Yau, Mei Kwan and Suen, Jacky (2019). Modulators of protease activated receptors. US9701711B2. |
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2019 Journal Article Diverse MR1-restricted T cells in mice and humansKoay, Hui-Fern, Gherardin, Nicholas A., Xu, Calvin, Seneviratna, Rebecca, Zhao, Zhe, Chen, Zhenjun, Fairlie, David P., McCluskey, James, Pellicci, Daniel G., Uldrich, Adam P. and Godfrey, Dale I. (2019). Diverse MR1-restricted T cells in mice and humans. Nature Communications, 10 (1) 2243, 2243. doi: 10.1038/s41467-019-10198-w |
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2019 Journal Article Crystal structures of protein-bound cyclic peptidesMalde, Alpeshkumar K., Hill, Timothy A., Iyer, Abishek and Fairlie, David P. (2019). Crystal structures of protein-bound cyclic peptides. Chemical Reviews, 119 (17) acs.chemrev.8b00807, 9861-9914. doi: 10.1021/acs.chemrev.8b00807 |
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2019 Journal Article Pharmacological inhibition of protease-activated receptor-2 reduces crescent formation in rat nephrotoxic serum nephritisHan, Yingjie, Tian, Lifang, Ma, Frank, Tesch, Greg, Vesey, David A., Gobe, Glenda C., Lohman, Rink-Jan, Morais, Christudas, Suen, Jacky Y., Fairlie, David P. and Nikolic-Paterson, David J. (2019). Pharmacological inhibition of protease-activated receptor-2 reduces crescent formation in rat nephrotoxic serum nephritis. Clinical and Experimental Pharmacology and Physiology, 46 (5) 1440-1681.13077, 456-464. doi: 10.1111/1440-1681.13077 |
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2019 Conference Publication Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 InflammationIyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY. |
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2019 Journal Article MAIT cells upregulate α4β7 in response to acute simian immunodeficiency virus/simian HIV infection but are resistant to peripheral depletion in pigtail macaquesJuno, Jennifer A., Wragg, Kathleen M., Amarasena, Thakshila, Meehan, Bronwyn S., Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., McCluskey, James, Eckle, Sidonia B. G. and Kent, Stephen J. (2019). MAIT cells upregulate α4β7 in response to acute simian immunodeficiency virus/simian HIV infection but are resistant to peripheral depletion in pigtail macaques. The Journal of Immunology, 202 (7), ji1801405-2120. doi: 10.4049/jimmunol.1801405 |
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2019 Journal Article Oxazole-benzenesulfonamide derivatives inhibit HIV-1 reverse transcriptase interaction with cellular eEF1A and reduce viral replicationRawle, Daniel J., Li, Dongsheng, Wu, Zhonglan, Wang, Lu, Choong, Marcus, Lor, Mary, Reid, Robert C., Fairlie, David P., Harris, Jonathan, Tachedjian, Gilda, Poulsen, Sally-Ann and Harrich, David (2019). Oxazole-benzenesulfonamide derivatives inhibit HIV-1 reverse transcriptase interaction with cellular eEF1A and reduce viral replication. Journal of Virology, 93 (12) e0023919. doi: 10.1128/jvi.00239-19 |
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2019 Journal Article Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellularKhalil, Zeinab G., Hill, Timothy A., De Leon Rodriguez, Luis M., Lohman, Rink-Jan, Hoang, Huy N., Reiling, Norbert, Hillemann, Doris, Brimble, Margaret A., Fairlie, David, Blumenthal, Antje and Capon, Robert J. (2019). Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular. Antimicrobial Agents and Chemotherapy, 63 (3) e01773-18. doi: 10.1128/AAC.01773-18 |
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2019 Other Outputs Supplementary Figure S1Iyer, Abishek, Humphries, Tyrone LR, Owens, Evan P, Zhao, Kong-Nan, Masci, Paul P, Gobe, Glenda C, Johnson, David W, Paterson, David Nikolic, Fairlie, David P and Vesey, David A (2019). Supplementary Figure S1. The University of Queensland. (Dataset) doi: 10.14264/uql.2019.810 |
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2019 Conference Publication Heterocycles for switching GPCR ligand conformation and activityFairlie, David, Reid, Robert, Rowley, Jessica, Wu, Kai-Chen, Yau, Mei-Kwan, Lim, Junxian and Iyer, Abishek (2019). Heterocycles for switching GPCR ligand conformation and activity. National Meeting of the American Chemical Society (ACS), Orlando, FL United States, 31 March-4 April 2019. Washington, DC United States: American Chemical Society. |
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2019 Other Outputs Supplementary Data tables for: Orally absorbed cyclic peptidesNielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2019). Supplementary Data tables for: Orally absorbed cyclic peptides. The University of Queensland. (Dataset) doi: 10.14264/uql.2019.213 |
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2019 Journal Article Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitroAlgate, Kent, Haynes, David, Fitzsimmons, Tracy, Romeo, Ornella, Wagner, Florence, Holson, Edward, Reid, Robert, Fairlie, David, Bartold, Peter and Cantley, Melissa (2019). Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro. Journal of Cellular Biochemistry, 121 (1) jcb.29137, 244-258. doi: 10.1002/jcb.29137 |
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2019 Conference Publication IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infectionWang, H., Kjer-Nielsen, L., Shi, M., Souza, D. C., Pediongco, T., Cao, H., Kostenko, L., Lim, X., Eckle, S., Meeha, B., Wang, B., Zhu, T., Mak, J., Fairlie, D., Teng, M., Rossjohn, J., Yu, D., Groth, B., McCluskey, J., Strugnell, R., Corbett, A. and Chen, Z. (2019). IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October, 2019. Weinheim, Germany: WILEY. doi: 10.1002/eji.201970400 |
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2018 Journal Article Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cellsNguyen, Hung, Kuril, Sandeepkumar, Bastian, David, Kim, Jisun, Zhang, Mengmeng, Vaena, Silvia G., Dany, Mohammed, Dai, Min, Heinrichs, Jessica Lauren, Daenthanasanmak, Anusara, Iamsawat, Supinya, Schutt, Steven, Fu, Jianing, Wu, Yongxia, Fairlie, David P., Atkinson, Carl, Ogretmen, Besim, Tomlinson, Stephen and Yu, Xue-Zhong (2018). Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. JCI Insight, 3 (24) e121697. doi: 10.1172/jci.insight.121697 |
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2018 Journal Article MAIT cells protect against pulmonary Legionella longbeachae infectionWang, Huimeng, D’Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C. and Chen, Zhenjun (2018). MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications, 9 (1) 3350, 3350. doi: 10.1038/s41467-018-05202-8 |
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2018 Conference Publication Chemical synthesis and applications of a novel fluorescent probe for human complement C3a receptorWu, Chongyang, de Araujo, Aline, Wu, Kai-Chen, Reid, Robert, Durek, Thomas, Lim, Junxian and Fairlie, David (2018). Chemical synthesis and applications of a novel fluorescent probe for human complement C3a receptor. 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, Boston Ma, Aug 19-23, 2018. WASHINGTON: AMER CHEMICAL SOC. |
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2018 Journal Article Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genesRamnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) e120274. doi: 10.1172/jci.insight.120274 |
