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2019 Conference Publication IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infectionWang, H., Kjer-Nielsen, L., Shi, M., Souza, D. C., Pediongco, T., Cao, H., Kostenko, L., Lim, X., Eckle, S., Meeha, B., Wang, B., Zhu, T., Mak, J., Fairlie, D., Teng, M., Rossjohn, J., Yu, D., Groth, B., McCluskey, J., Strugnell, R., Corbett, A. and Chen, Z. (2019). IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October, 2019. Weinheim, Germany: WILEY. doi: 10.1002/eji.201970400 |
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2018 Journal Article Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cellsNguyen, Hung, Kuril, Sandeepkumar, Bastian, David, Kim, Jisun, Zhang, Mengmeng, Vaena, Silvia G., Dany, Mohammed, Dai, Min, Heinrichs, Jessica Lauren, Daenthanasanmak, Anusara, Iamsawat, Supinya, Schutt, Steven, Fu, Jianing, Wu, Yongxia, Fairlie, David P., Atkinson, Carl, Ogretmen, Besim, Tomlinson, Stephen and Yu, Xue-Zhong (2018). Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. JCI Insight, 3 (24) ARTN e121697. doi: 10.1172/jci.insight.121697 |
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2018 Journal Article MAIT cells protect against pulmonary Legionella longbeachae infectionWang, Huimeng, D’Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C. and Chen, Zhenjun (2018). MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications, 9 (1) 3350, 3350. doi: 10.1038/s41467-018-05202-8 |
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2018 Conference Publication Chemical synthesis and applications of a novel fluorescent probe for human complement C3a receptorWu, Chongyang, de Araujo, Aline, Wu, Kai-Chen, Reid, Robert, Durek, Thomas, Lim, Junxian and Fairlie, David (2018). Chemical synthesis and applications of a novel fluorescent probe for human complement C3a receptor. 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, Boston Ma, Aug 19-23, 2018. WASHINGTON: AMER CHEMICAL SOC. |
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2018 Journal Article Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genesRamnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) ARTN e120274. doi: 10.1172/jci.insight.120274 |
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2018 Journal Article Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasisKim, Soo-Hyun, Redvers, Richard P., Chi, Lap Hing, Ling, Xiawei, Lucke, Andrew J., Reid, Robert C., Fairlie, David P., Baptista Moreno Martin, Ana Carolina, Anderson, Robin L., Denoyer, Delphine and Pouliot, Normand (2018). Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis. Disease Models and Mechanisms, 11 (7) Y, DMM034850. doi: 10.1242/dmm.034850 |
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2018 Conference Publication Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colonVarelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.15 |
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2018 Journal Article An overview on the identification of MAIT cell antigensKjer-Nielsen, Lars, Corbett, Alexandra J., Chen, Zhenjun, Liu, Ligong, Mak, Jeffrey Y. W., Godfrey, Dale I., Rossjohn, Jamie, Fairlie, David P., McCluskey, James and Eckle, Sidonia B. G. (2018). An overview on the identification of MAIT cell antigens. Immunology and Cell Biology, 96 (6), 573-587. doi: 10.1111/imcb.12057 |
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2018 Journal Article Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteinsde Araujo, Aline D., Lim, Junxian, Wu, Kai-Chen, Xiang, Yibin, Good, Andrew C., Skerlj, Renato and Fairlie, David P. (2018). Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteins. Journal of Medicinal Chemistry, 61 (7), 2962-2972. doi: 10.1021/acs.jmedchem.8b00010 |
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2018 Journal Article Recipient mucosal-associated invariant T cells control GVHD within the colonVarelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646 |
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2018 Journal Article Lysine deacetylases and regulated glycolysis in macrophagesShakespear, Melanie R., Iyer, Abishek, Cheng, Catherine Youting, Das Gupta, Kaustav, Singhal, Amit, Fairlie, David P. and Sweet, Matthew J. (2018). Lysine deacetylases and regulated glycolysis in macrophages. Trends in Immunology, 39 (6), 473-488. doi: 10.1016/j.it.2018.02.009 |
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2018 Journal Article Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myelomaGherardin, Nicholas A, Loh, Liyen, Admojo, Lorenztino, Davenport, Alexander J, Richardson, Kelden, Rogers, Amy, Darcy, Phillip K, Jenkins, Misty R., Prince, H. Miles, Harrison, Simon J., Quach, Hang, Fairlie, David P., Kedzierska, Katherine, McCluskey, James, Uldrich, Adam P, Neeson, Paul J., Ritchie, David S. and Godfrey, Dale I. (2018). Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma. Scientific reports, 8 (1) 4159, 4159. doi: 10.1038/s41598-018-22130-1 |
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2018 Journal Article Chemically Diverse Helix-Constrained Peptides Using Selenocysteine CrosslinkingDantas de Araujo, Aline, Perry, Samuel R. and Fairlie, David P. (2018). Chemically Diverse Helix-Constrained Peptides Using Selenocysteine Crosslinking. Organic Letters, 20 (5), 1453-1456. doi: 10.1021/acs.orglett.8b00233 |
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2018 Journal Article Human blood MAIT cell subsets defined using MR1 tetramersGherardin, Nicholas A., Souter, Michael N. T., Koay, Hui-Fern, Mangas, Kirstie M., Seemann, Torsten, Stinear, Timothy P., Eckle, Sidonia B. G., Berzins, Stuart P., d'Udekem, Yves, Konstantinov, Igor E., Fairlie, David P., Ritchie, David S., Neeson, Paul J., Pellicci, Daniel G., Uldrich, Adam P., McCluskey, James and Godfrey, Dale I. (2018). Human blood MAIT cell subsets defined using MR1 tetramers. Immunology and Cell Biology, 96 (5), 507-525. doi: 10.1111/imcb.12021 |
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2018 Journal Article A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cellsJiang, Yuhong, Yau, Mei-Kwan, Lim, Junxian, Wu, Kai-Chen, Xu, Weijun, Suen, Jacky Y and Fairlie, David P (2018). A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells. The Journal of pharmacology and experimental therapeutics, 364 (2), 246-257. doi: 10.1124/jpet.117.245027 |
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2018 Journal Article Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori InfectionD'Souza, Criselle, Pediongco, Troi, Wang, Huimeng, Scheerlinck, Jean-Pierre Y., Kostenko, Lyudmila, Esterbauer, Robyn, Stent, Andrew W., Eckle, Sidonia B. G., Meehan, Bronwyn S., Strugnell, Richard A., Cao, Hanwei, Liu, Ligong, Mak, Jeffrey Y. W., Lovrecz, George, Lu, Louis, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Every, Alison L., Chen, Zhenjun and Corbett, Alexandra J. (2018). Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection. Journal of Immunology, 200 (5), 1901-1916. doi: 10.4049/jimmunol.1701512 |
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2018 Journal Article Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeabilityPerry, Samuel R, Hill, Timothy A, de Araujo, Aline D, Hoang, Huy N and Fairlie, David P (2018). Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability. Organic & biomolecular chemistry, 16 (3), 367-371. doi: 10.1039/c7ob02952g |
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2018 Journal Article Chemical approaches to modulating complement-mediated diseasesIyer, Abishek, Xu, Weijun, Reid, Robert C and Fairlie, David P (2018). Chemical approaches to modulating complement-mediated diseases. Journal of Medicinal Chemistry, 61 (8), 3253-3276. doi: 10.1021/acs.jmedchem.7b00882 |
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2018 Conference Publication RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver diseaseRamnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018). RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. International Liver Congress (ILC), Paris, France, 11-15 April, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(18)31040-7 |
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2018 Conference Publication Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colonVarelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology Meeting, Austin Tx, 4-8 May 2018. Bethesda, MD United States: American Association of Immunologists. |
