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Associate Professor Marloes Nitert Dekker
Associate Professor

Marloes Nitert Dekker

Email: 
Phone: 
+61 7 336 54633

Overview

Background

Dr Marloes Dekker Nitert is an Associate Professor at The University of Queensland. Marloes is a biomedical researcher with a PhD from Lund University in Sweden. Her research focuses on the role of metabolism in complications of pregnancy. She currently heads a laboratory research group at the School of Chemistry and Molecular Biosciences studying the role of metabolism in pregnancy complications and especially how the gut microbiome contributes to a healthy pregnancy and to pregnancy complications. Marloes works closely together with clinician-scientists and clinicians at the Royal Brisbane and Women’s Hospital and the Mater Mothers' Hospital to do her translational research. Marloes is a board member of the Australian Society for Medical Research and a past Council member of the Society of Obstetric Medicine Australia and New Zealand.

Availability

Associate Professor Marloes Nitert Dekker is:
Available for supervision

Qualifications

  • Licentiate of Medical Sciences, Linköping University
  • Doctor of Philosophy of Medical Sciences, Lund University
  • Postgraduate Certificate in Medical Research, London School of Hygiene & Tropical Medicine

Research interests

  • Microbiome in pregnancy

  • Complications of pregnancy

Works

Search Professor Marloes Nitert Dekker’s works on UQ eSpace

163 works between 1998 and 2025

141 - 160 of 163 works

2011

Journal Article

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

Yang, B. T., Dayeh, T. A., Kirkpatrick, C. L., Taneera, J., Kumar, R., Groop, L., Wollheim, C. B., Nitert, M. D. and Ling, C. (2011). Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets. Diabetologia, 54 (2), 360-367. doi: 10.1007/s00125-010-1967-6

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

2011

Journal Article

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

Koeck, Thomas, Olsson, Anders H., Nitert, Marloes Dekker, Sharoyko, Vladimir V., Ladenvall, Claes, Kotova, Olga, Reiling, Erwin, Ronn, Tina, Parikh, Hemang, Taneera, Jalal, Eriksson, Johan G., Metodiev, Metodi D., Larsson, Nils-Goran, Balhuizen, Alexander, Luthman, Holger, Stancakova, Alena, Kuusisto, Johanna, Laakso, Markku, Poulsen, Pernille, Vaag, Allan, Groop, Leif, Lyssenko, Valeriya, Mulder, Hindrik and Ling, Charlotte (2011). A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes. Cell Metabolism, 13 (1), 80-91. doi: 10.1016/j.cmet.2010.12.007

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

2011

Book Chapter

Epigenetics and type 2 diabetes

Ling, Charlotte, Ronn, Tina and Nitert, Marloes Dekker (2011). Epigenetics and type 2 diabetes. Epigenetic aspects of chronic diseases. (pp. 135-145) edited by Helmtrud I. Roach, Felix Bronner and Richard O.C. Oreffo. London, United Kingdom: Springer. doi: 10.1007/978-1-84882-644-1_9

Epigenetics and type 2 diabetes

2010

Journal Article

Apelin is a novel islet peptide

Ringstrom, Camilla, Nitert, Marloes Dekker, Bennet, Hedvig, Fex, Malin, Valet, Phillipe, Rehfeld, Jens F., Friis-Hansen, Lennart and Wierup, Nils (2010). Apelin is a novel islet peptide. Regulatory Peptides, 162 (1-3), 44-51. doi: 10.1016/j.regpep.2010.03.005

Apelin is a novel islet peptide

2010

Conference Publication

Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes

Nitert, M. D., Dayeh, T., Lang, S., Elgzyri, T., Yang, B., Hansson, O., Ronn, T., Eriksson, K. F., Groop, L. and Ling, C. (2010). Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Springer.

Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes

2010

Conference Publication

Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells

Voss, U., Riva, M., Dekker Nitert, M. N., Ling, C., Lindqvist, A. and Wierup, N. (2010). Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00125-010-1872-z

Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells

2010

Conference Publication

Apelin is expressed in human and rodent islets and regulates insulin secretion

Ringstrom, Camilla, Nitert, Marloes Dekker, Bennet, Hedvig, Fex, Malin, Valet, Philippe, Rehfeld, Jens F., Friis-Hansen, Lennart and Wierup, Nils (2010). Apelin is expressed in human and rodent islets and regulates insulin secretion. 18th International Symposium on Regulatory Peptides, Belfast, United Kingdom, 5 - 8 September 2010. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.regpep.2010.07.059

Apelin is expressed in human and rodent islets and regulates insulin secretion

2010

Conference Publication

A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it

Malmgren, S., Sharoyko, V. V., Nicholls, D. G., Nagorny, C. L. F., Spegel, P., Nitert, M. D., Mulder, H. and Ling, C. (2010). A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it. 46th Annual Meeting of the European Association for the Study-of-Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00125-010-1872-z

A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it

2010

Conference Publication

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus

Travers, M. E., Nitert, M. D., Mackay, D. J. G., Lindgren, C. M., Groop, L., Gloyn, A. L. and McCarthy, M. I. (2010). Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Springer.

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus

2010

Conference Publication

Stimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans

Bennet, H., Nagorny, C. L. F., Wierup, N., Dekker-Nitert, M., Lernmark, A. and Fex, M. (2010). Stimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Springer.

Stimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans

2009

Journal Article

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

Fex, M., Haemmerle, G., Wierup, N., Dekker-Nitert, M., Rehn, M., Ristow, M., Zechner, R., Sundler, F., Holm, C., Eliasson, L. and Mulder, H. (2009). A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis. Diabetologia, 52 (2), 271-280. doi: 10.1007/s00125-008-1191-9

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

2009

Conference Publication

Disruption of TFB1M impairs insulin secretion in beta cells

Kock, T., Nitert, M. D., Olsson, A., Kotova, O., Stamenkovic, J., Lyssenko, V., Groop, L., Luthman, H., Ling, C. and Mulder, H. (2009). Disruption of TFB1M impairs insulin secretion in beta cells. 45th Annual Meeting of the European Association for the Study of Diabetes, Vienna, Austria, 30 September - 2 October 2009. Springer.

Disruption of TFB1M impairs insulin secretion in beta cells

2009

Conference Publication

5-hydroxytryptamine exposure stimulates insulin secretion in clonal beta cells but not in islets of Langerhans

Fex, M., Bennet, H., Nagorny, C., Nitert, M. D., Wierup, N. and Lernmark, A. (2009). 5-hydroxytryptamine exposure stimulates insulin secretion in clonal beta cells but not in islets of Langerhans. 45th Annual Meeting of the European Association for the Study of Diabetes, Vienna, Austria, 30 September - 2 October 2009. Springer.

5-hydroxytryptamine exposure stimulates insulin secretion in clonal beta cells but not in islets of Langerhans

2008

Journal Article

CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells

Nitert, Marloes Dekker, Nagorny, Cecilia L. F., Wendt, Anna, Eliasson, Lena and Mulder, Hindrik (2008). CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells. Journal of Molecular Endocrinology, 41 (1-2), 1-11. doi: 10.1677/JME-07-0133

CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells

2007

Journal Article

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57I3L/6J background exhibit unaltered glucose tolerance (vol 194, pg 551, 2007)

Fex, M., Wierup, N., Nitert, M. D., Ristow, M. and Mulder, H. (2007). Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57I3L/6J background exhibit unaltered glucose tolerance (vol 194, pg 551, 2007). Journal of Endocrinology, 195 (3), 537-537. doi: 10.1677/JOE-07-0161e

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57I3L/6J background exhibit unaltered glucose tolerance (vol 194, pg 551, 2007)

2007

Journal Article

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance

Fex, Malin, Wierup, Nils, Nitert, Marloes Dekker, Ristow, Michael and Mulder, Hindrik (2007). Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance. Journal of Endocrinology, 194 (3), 551-555. doi: 10.1677/JOE-07-0161

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance

2007

Journal Article

Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet

Fex, M., Nitert, M. Dekker, Wierup, N., Sundler, F., Ling, C. and Mulder, H. (2007). Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet. Diabetologia, 50 (1), 74-83. doi: 10.1007/s00125-006-0464-4

Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet

2007

Conference Publication

CaV 1.2 channels, rather than CaV 1.3 and CaV 2.3 channels, permit insulin secretion from INS-I 832/13

Nitert, M. D., Wendt, A., Eliasson, L. and Mulder, H. (2007). CaV 1.2 channels, rather than CaV 1.3 and CaV 2.3 channels, permit insulin secretion from INS-I 832/13. 43rd annual meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, 18-21 September 2007. Springer.

CaV 1.2 channels, rather than CaV 1.3 and CaV 2.3 channels, permit insulin secretion from INS-I 832/13

2006

Journal Article

Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells

Chisalita, Simona I., Nitert, Marloes Dekker and Arnqvist, Hans J. (2006). Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells. Growth Hormone & Igf Research, 16 (4), 258-266. doi: 10.1016/j.ghir.2006.06.003

Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells

2005

Journal Article

IGF-I/insulin hybrid receptors in human endothelial cells

Nitert, Marloes Dekker, Chisalita, Simona I., Olsson, Karolina, Bornfeldt, Karin E. and Arnqvist, Hans J. (2005). IGF-I/insulin hybrid receptors in human endothelial cells. Molecular and Cellular Endocrinology, 229 (1-2), 31-37. doi: 10.1016/j.mce.2004.10.003

IGF-I/insulin hybrid receptors in human endothelial cells

Funding

Current funding

  • 2022 - 2026
    LESTR Low Emission Saliva Test for Ruminants
    Meat & Livestock Australia
    Open grant
  • 2021 - 2025
    Assessing hyperglycaemia in women pregnant after bariatric surgery
    Diabetes Australia Research Program
    Open grant

Past funding

  • 2023 - 2025
    What is the role of the gut microbiota in regulating maternal metabolism of bile acids in pregnancy in women with, or at high risk of ICP.. (University of Adelaide administered Ferring)
    University of Adelaide
    Open grant
  • 2021 - 2022
    Effect of high intensity interval training (HIIT) on human gut microbiome functional diversity, inflammation and body composition in colorectal cancer survivors
    University of Newcastle
    Open grant
  • 2020 - 2022
    The role of increased gut permeability in hypertensive disorders of pregnancy
    Royal Australasian College of Physicians
    Open grant
  • 2018
    Epifluorescent and live-cell imaging microscopes for the investigation of host-pathogen interactions and for molecular and cellular biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    Antibiotics in pregnancy: unintended effects on the microbiome, maternal metabolism and infant body composition?
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2018
    Linking maternal and infant microbiome: effects of GDM or effects of probiotics?
    Diabetes Australia Research Program
    Open grant
  • 2017 - 2018
    Long-term consequences of altered neonatal adiposity
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2018
    Short chain fatty acids - gut microbiome messengers regulating blood pressure in pregnancy?
    UQ Early Career Researcher
    Open grant
  • 2017 - 2021
    Trophoblast cell-cell fusion in preeclampsia
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Assessing ketone production after a meal with restricted carbohydrate in women with gestational diabetes
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2017
    Is the resistome in the gut microbiome in pregnant women changing pregnancy outcomes?
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2018
    Postprandial triglycerides in diabetes in pregnancy: a pilot study
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2016
    Periconception weight loss and the epigenetic regulation of stress and growth in the infant
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2016
    Your microbiome or your mother's? The relationship between the microbiomes of mothers and babies
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2015
    Metabolic toxins and placental functions
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2015
    Does preconception weight loss alter the neonatal stress response to heel stick? A pilot study
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2014
    RBWH Post Doctoral Fellowship: The gut microbiome: A secret ingredient in the development of gestational diabetes?
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2015
    The gut microbiome: A secret ingredient in the development of gestational diabetes?
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2015
    Validation of a triglyceride meter for home monitoring of triglyceride levels in pregnancy
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012 - 2018
    Impact of metformin treatment for gestational diabetes on gestational lipid metabolism and infant body composition: A prospective observational study
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012 - 2016
    A randomized controlled trial of probiotics to prevent gestational diabetes
    NHMRC Project Grant
    Open grant

Supervision

Availability

Associate Professor Marloes Nitert Dekker is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Comparing the composition of the gut microbiota between pregnant women with and without previous bariatric surgery

    Bariatric surgery, a surgery used to reduce the size of the stomach and thereby reduce body weight, changes dietary intake. Outside pregnancy, the surgery and the change in diet are associated with changes to the composition of the gut microbiota. Pregnancy also changes the composition of the gut microbiota and may contribute to the physiological changes in metabolism of the mother that ensure adequate nutrient supply to the baby. It is not clear if women who had bariatric surgery prior to falling pregnant have similar or different changes to the composition of the gut microbiota. In this project, you would do a comparison of the composition of the gut microbiota between these two groups of women and link this to the levels of biochemical and hormonal markers.

Supervision history

Current supervision

Completed supervision

Media

Enquiries

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communications@uq.edu.au