Dr Ismail Sebina
Dr

Ismail Sebina

Email: 

Background

Dr Ismail Sebina is a Research Fellow at the Frazer Institute-The University of Queensland, under the mentorship of Prof. Gabrielle Belz. He holds a PhD in immunology from The University of Queensland (awarded in 2017) and a Master’s degree in the Immunology of Infectious Diseases from the London School of Hygiene and Tropical Medicine (LSHTM; UK). He has contributed to discovery and translational immunological research in several laboratories across the USA, the UK, Uganda, and Australia, implementing studies in both preclinical mouse models and humans. He completed six years of rigorous postdoctoral training in immunology at the University of Washington (USA) and QIMR Berghofer Medical Research institute (QIMR Berghofer; Australia). He has demonstrated a strong record of publications in high-impact journals such as Immunity, Science Immunology, JCI and PNAS. He has regularly presented his findings at national and international conferences (e.g. Keystone Symposium and ASI), furthering my engagement with the scientific community. Dr. Sebina's primary research focus revolves around uncovering the mechanisms that underpin natural and vaccine-induced immunity to infections. With a passion for improving maternal, newborn, and child health, he also explores novel immunological strategies that have the potential to revolutionize healthcare practices in this area.

Availability

Dr Ismail Sebina is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Biomedical Science, Makerere University
  • Masters (Extended) of Immunology, London School of Hygiene and Tropical Medicine
  • Doctor of Philosophy of Immunology, The University of Queensland

Research interests

  • Infection and Immunity

  • Vaccine Immunology

  • Immunology of Infectious Diseases

  • Maternal-Newborn Immunity

  • Humoral immunity

Search Professor Ismail Sebina’s works on UQ eSpace

35 works between 2011 and 2024
All (35) Journal Article (31) Conference Publication (3) Other Outputs (1)

21 - 35 of 35 works

2017

Journal Article

IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection

Sebina, I., Fogg, L. G., James, K. R., Soon, M. S. F., Akter, J., Thomas, B. S., Hill, G. R., Engwerda, C. R. and Haque, A. (2017). IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection. Parasite Immunology, 39 (10) e12455, e12455. doi: 10.1111/pim.12455

IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection

2017

Journal Article

Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection

Khoury, David S., Cromer, Deborah, Akter, Jasmin, Sebina, Ismail, Elliott, Trish, Thomas, Bryce S., Soon, Megan S. F., James, Kylie R., Best, Shannon E., Haque, Ashraful and Davenport, Miles P. (2017). Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection. Proceedings of the National Academy of Sciences of the United States of America, 114 (29), 7701-7706. doi: 10.1073/pnas.1618939114

Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection

2017

Other Outputs

Immunological mechanisms controlling blood-stage parasites in mouse models of malaria

Sebina, Ismail (2017). Immunological mechanisms controlling blood-stage parasites in mouse models of malaria. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2017.482

Immunological mechanisms controlling blood-stage parasites in mouse models of malaria

2017

Journal Article

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFHfate bifurcation in malaria

Lönnberg, Tapio, Svensson, Valentine, James, Kylie R., Fernandez-Ruiz, Daniel, Sebina, Ismail, Montandon, Ruddy, Soon, Megan S. F., Fogg, Lily G., Nair, Arya Sheela, Liligeto, Urijah N., Stubbington, Michael J. T., Ly, Lam-Ha, Bagger, Frederik Otzen, Zwiessele, Max, Lawrence, Neil D., Souza-Fonseca-Guimaraes, Fernando, Bunn, Patrick T., Engwerda, Christian R., Heath, William R., Billker, Oliver, Stegle, Oliver, Haque, Ashraful and Teichmann, Sarah A. (2017). Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFHfate bifurcation in malaria. Science Immunology, 2 (9) eaal2192, eaal2192. doi: 10.1126/sciimmunol.aal2192

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFHfate bifurcation in malaria

2016

Journal Article

IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection

Sebina, Ismail, James, Kylie R., Soon, Megan S. F., Fogg, Lily G., Best, Shannon E., Labastida Rivera, Fabian de, Montes de Oca, Marcela, Amante, Fiona H., Thomas, Bryce S., Beattie, Lynette, Souza-Fonseca-Guimaraes, Fernando, Smyth, Mark J., Hertzog, Paul J., Hill, Geoffrey R., Hutloff, Andreas, Engwerda, Christian R. and Haque, Ashraful (2016). IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection. PLoS Pathogens, 12 (11) e1005999, e1005999. doi: 10.1371/journal.ppat.1005999

IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection

2016

Conference Publication

Resolving T helper cell fate decisions using single-cell RNA-sequencing

Loennberg, Tapio, James, Kylie, Svensson, Valentine, Fernandez-Ruiz, Daniel, Sebina, Ismail, Montandon, Ruddy, Soon, Megan, Stubbington, Michael, Souza-Fonseca-Guimaraes, Fernando, Heath, William, Billker, Oliver, Haque, Ashraful and Teichmann, Sarah (2016). Resolving T helper cell fate decisions using single-cell RNA-sequencing. 43rd Meeting of the Scandinavian Society for Immunology (SSI), Turku, Finland, 10-13 May 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing.

Resolving T helper cell fate decisions using single-cell RNA-sequencing

2015

Journal Article

Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria

Khoury, David S., Cromer, Deborah, Best, Shannon E., James, Kylie R., Sebina, Ismail, Haque, Ashraful and Davenport, Miles P. (2015). Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria. Scientific Reports, 5 (9412) 9412. doi: 10.1038/srep09412

Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria

2015

Journal Article

Coinfection with blood-stage plasmodium promotes systemic type I interferon production during pneumovirus infection but impairs inflammation and viral control in the lung

Edwards, Chelsea L., Zhang, Vivian, Werder, Rhiannon B., Best, Shannon E., Sebina, Ismail, James, Kylie R., Faleiro, Rebecca J., Rivera, Fabian de Labastida, Amante, Fiona H., Engwerda, Christian R., Phipps, Simon and Haque, Ashraful (2015). Coinfection with blood-stage plasmodium promotes systemic type I interferon production during pneumovirus infection but impairs inflammation and viral control in the lung. Clinical and Vaccine Immunology, 22 (5), 477-483. doi: 10.1128/CVI.00051-15

Coinfection with blood-stage plasmodium promotes systemic type I interferon production during pneumovirus infection but impairs inflammation and viral control in the lung

2015

Journal Article

Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection

Edwards, Chelsea L., Best, Shannon E., Gun, Sin Yee, Claser, Carla, James, Kylie R., de Oca, Marcela M., Sebina, Ismail, Rivera, Fabian de Labastida, Amante, Fiona H., Hertzog, Paul J., Engwerda, Christian R., Renia, Laurent and Haque, Ashraful (2015). Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection. European Journal of Immunology, 45 (1), 130-141. doi: 10.1002/eji.201444824

Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection

2014

Journal Article

Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity

Sebina, Ismail, Biraro, Irene A., Dockrell, Hazel M., Elliott, Alison M. and Cose, Stephen (2014). Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity. PLoS One, 9 (9) e106796, e106796. doi: 10.1371/journal.pone.0106796

Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity

2014

Journal Article

Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity

Haque, Ashraful, Best, Shannon E., De Oca, Marcela Montes, James, Kylie R., Ammerdorffer, Anne, Edwards, Chelsea L., De Labastida Rivera, Fabian, Amante, Fiona H., Bunn, Patrick T., Sheel, Meru, Sebina, Ismail, Koyama, Motoko, Varelias, Antiopi, Hertzog, Paul J., Kalinke, Ulrich, Gun, Sin Yee, Renia, Laurent, Ruedl, Christiane, MacDonald, Kelli P.A., Hill, Geoffrey R. and Engwerda, Christian R. (2014). Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity. Journal of Clinical Investigation, 124 (6), 2483-2496. doi: 10.1172/JCI70698

Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity

2013

Conference Publication

Risk factors for seropositivity to Kaposi sarcoma-associated herpesvirus among children in Uganda

Wakeham, Katie, Webb, Emily L., Sebina, Ismail, Nalwoga, Angela, Muhangi, Lawrence, Miley, Wendell, Johnston, W. Thomas, Ndibazza, Juliet, Whitby, Denise, Newton, Robert and Elliott, Alison M. (2013). Risk factors for seropositivity to Kaposi sarcoma-associated herpesvirus among children in Uganda. 14th International Workshop on Kaposi's Sarcoma Herpesvirus (KSHV) and Related Agents, Helsinki, Finland, August 2011. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/QAI.0b013e31828a7056

Risk factors for seropositivity to Kaposi sarcoma-associated herpesvirus among children in Uganda

2012

Journal Article

Long-lived memory B-cell responses following BCG vaccination

Sebina, Ismail, Cliff, Jacqueline M., Smith, Steven G., Nogaro, Sarah, Webb, Emily L., Riley, Eleanor M., Dockrell, Hazel M., Elliott, Alison M., Hafalla, Julius C. R. and Cose, Stephen (2012). Long-lived memory B-cell responses following BCG vaccination. PLoS One, 7 (12) e51381, e51381. doi: 10.1371/journal.pone.0051381

Long-lived memory B-cell responses following BCG vaccination

2012

Journal Article

Determining Mycobacterium tuberculosis infection among BCG-immunised Ugandan children by T-SPOT.TB and tuberculin skin testing

Nkurunungi, Gyaviira, Lutangira, Jimreeves E., Lule, Swaib A., Akurut, Hellen, Kizindo, Robert, Fitchett, Joseph R., Kizito, Dennison, Sebina, Ismail, Muhangi, Lawrence, Webb, Emily L., Cose, Stephen and Elliott, Alison M. (2012). Determining Mycobacterium tuberculosis infection among BCG-immunised Ugandan children by T-SPOT.TB and tuberculin skin testing. PLoS One, 7 (10) e47340, e47340. doi: 10.1371/journal.pone.0047340

Determining Mycobacterium tuberculosis infection among BCG-immunised Ugandan children by T-SPOT.TB and tuberculin skin testing

2011

Journal Article

Parasite infection is associated with Kaposi's sarcoma associated herpesvirus (KSHV) in Ugandan women

Wakeham, Katie, Webb, Emily L., Sebina, Ismail, Muhangi, Lawrence, Miley, Wendell, Johnson, W. Thomas, Ndibazza, Juliet, Elliott, Alison M., Whitby, Denise and Newton, Robert (2011). Parasite infection is associated with Kaposi's sarcoma associated herpesvirus (KSHV) in Ugandan women. Infectious Agents and Cancer, 6 (1) 15, 15. doi: 10.1186/1750-9378-6-15

Parasite infection is associated with Kaposi's sarcoma associated herpesvirus (KSHV) in Ugandan women

Availability

Dr Ismail Sebina is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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