Dr Meihua Yu
Dr

Meihua Yu

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Background

Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.

Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.

Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.

Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).

Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.

Availability

Dr Meihua Yu is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Meihua Yu’s works on UQ eSpace

154 works between 2006 and 2026
All (154) Journal Article (145) Other Outputs (1) Conference Publication (7) Book Chapter (1)

101 - 120 of 154 works

2016

Journal Article

Silica nanopollens enhance adhesion for long-term bacterial inhibition

Song, Hao, Ahmad Nor, Yusilawati, Yu, Meihua, Yang, Yannan, Zhang, Jun, Zhang, Hongwei, Xu, Chun, Mitter, Neena and Yu, Chengzhong (2016). Silica nanopollens enhance adhesion for long-term bacterial inhibition. Journal of the Americal Chemical Society, 138 (20), 6455-6462. doi: 10.1021/jacs.6b00243

Silica nanopollens enhance adhesion for long-term bacterial inhibition

2016

Journal Article

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

Wang, Yue, Nor, Yusilawati Ahmad, Song, Hao, Yang, Yannan, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4 (15), 2646-2653. doi: 10.1039/c6tb00053c

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

2016

Journal Article

Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery

Meka, Anand Kumar, Niu, Yuting, Karmakar, Surajit, Hartono, Sandy Budi, Zhang, Jun, Lin, Chun Xiang Cynthia, Zhang, Hongwei, Whittaker, Andrew, Jack, Kevin, Yu, Meihua and Yu, Chengzhong (2016). Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery. ChemNanoMat, 2 (3), 220-225. doi: 10.1002/cnma.201600021

Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery

2016

Journal Article

Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient

Yang, Yannan, Bernardi, Stefano, Song, Hao, Zhang, Jun, Yu, Meihua, Reid, James C., Strounina, Ekaterina, Searles, Debra J. and Yu, Chengzhong (2016). Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient. Chemistry of Materials, 28 (3), 704-707. doi: 10.1021/acs.chemmater.5b03963

Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient

2015

Journal Article

Size-dependent gene delivery of amine-modified silica nanoparticles

Yu, Meihua, Niu, Yuting, Zhang, Jun, Zhang, Hongwei, Yang, Yannan, Taran, Elena, Jambhrunkar, Siddharth, Gu, Wenyi, Thorn, Peter and Yu, Chengzhong (2015). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9 (2), 291-305. doi: 10.1007/s12274-015-0909-5

Size-dependent gene delivery of amine-modified silica nanoparticles

2015

Journal Article

Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery

Niu, Yuting, Yu, Meihua, Meka, Anand, Liu, Yang, Zhang, Jun, Yang, Yannan and Yu, Chengzhong (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4 (2), 212-219. doi: 10.1039/c5tb01911g

Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery

2015

Journal Article

Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery

Xu, Chun, Yu, Meihua, Noonan, Owen, Zhang, Jun, Song, Hao, Zhang, Hongwei, Lei, Chang, Niu, Yuting, Huang, Xiaodan, Yang, Yannan and Yu, Chengzhong (2015). Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery. Small, 11 (44), 5949-5955. doi: 10.1002/smll.201501449

Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery

2015

Journal Article

Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway

Zhang, Hongwei, Yu, Meihua, Song, Hao, Noonan, Owen, Zhang, Jun, Yang, Yannan, Zhou, Liang and Yu, Chengzhong (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27 (18), 6297-6304. doi: 10.1021/acs.chemmater.5b01993

Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway

2015

Journal Article

Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery

Niu, Yuting, Yu, Meihua, Zhang, Jun, Yang, Yannan, Xu, Chun, Yeh, Michael, Taran, Elena, Hou, Jeff Jia Cheng, Gray, Peter P. and Yu, Chengzhong (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3 (43), 8477-8485. doi: 10.1039/c5tb01405k

Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery

2015

Journal Article

Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery

Ahmad Nor, Yusilawati, Niu, Yuting, Karmakar, Surajit, Zhou, Liang, Xu, Chun, Zhang, Jun, Zhang, Hongwei, Yu, Meihua, Mahony, Donna, Mitter, Neena, Cooper, Matthew and Yu, Cheng Zhong (2015). Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery. ACS Central Science, 1 (6), 328-334. doi: 10.1021/acscentsci.5b00199

Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery

2015

Journal Article

Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway

Gu, Wenyi, Prasadam, Indira, Yu, Meihua, Zhang, Fengxia, Ling, Patrick, Xiao, Yin and Yu, Chengzhong (2015). Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. BMC Cancer, 15 (1) 609, 1-11. doi: 10.1186/s12885-015-1614-1

Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway

2015

Journal Article

Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy

Yang, Yannan, Yu, Meihua, Song, Hao, Wang, Yue and Yu, Chengzhong (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7 (28), 11894-11898. doi: 10.1039/c5nr02769a

Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy

2015

Journal Article

Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery

Yang, Yannan, Niu, Yuting, Zhang, Jun, Meka, Anand Kumar, Zhang, Hongwei, Xu, Chun, Lin, Chun Xiang Cynthia, Yu, Meihua and Yu, Chengzhong (2015). Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery. Small, 11 (23), 2743-2749. doi: 10.1002/smll.201402779

Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery

2015

Journal Article

New isoprenylated phenolic compounds from Morus laevigata

Wang, Meng, Yu, Bang-Wei, Yu, Mei-Hua, Gao, Li-Xin, Li, Jing-Ya, Wang, He-Yao, Li, Jia and Hou, Ai-Jun (2015). New isoprenylated phenolic compounds from Morus laevigata. Chemistry & Biodiversity, 12 (6), 937-945. doi: 10.1002/cbdv.201400210

New isoprenylated phenolic compounds from Morus laevigata

2015

Journal Article

High-Density Genetic Linkage Map Construction and QTL Mapping of Grain Shape and Size in the Wheat Population Yanda1817 x Beinong6

Wu, Qiu-Hong, Chen, Yong-Xing, Zhou, Sheng-Hui, Fu, Lin, Chen, Jiao-Jiao, Xiao, Yao, Zhang, Dong, Ouyang, Shu-Hong, Zhao, Xiao-Jie, Cui, Yu, Zhang, De-Yun, Liang, Yong, Wang, Zhen-Zhong, Xie, Jing-Zhong, Qin, Jin-Xia, Wang, Guo-Xin, Li, De-Lin, Huang, Yin-Lian, Yu, Mei-Hua, Lu, Ping, Wang, Li-Li, Wang, Ling, Wang, Hao, Dang, Chen, Li, Jie, Zhang, Yan, Peng, Hui-Ru, Yuan, Cheng-Guo, You, Ming-Shan ... Liu, Zhi-Yong (2015). High-Density Genetic Linkage Map Construction and QTL Mapping of Grain Shape and Size in the Wheat Population Yanda1817 x Beinong6. Plos One, 10 (2) e0118144. doi: 10.1371/journal.pone.0118144

High-Density Genetic Linkage Map Construction and QTL Mapping of Grain Shape and Size in the Wheat Population Yanda1817 x Beinong6

2015

Journal Article

Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes

Liu, Chao, Yu, Meihua, Li, Yang, Li, Jiansheng, Wang, Jing, Yu, Chengzhong and Wang, Lianjun (2015). Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes. Nanoscale, 7 (27), 11580-11590. doi: 10.1039/c5nr02389k

Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes

2015

Journal Article

Diels-Alder adducts with PTP1B inhibition from Morus notabilis

Wang, Meng, Gao, Li-Xin, Wang, Jue, Li, Jing-Ya, Yu, Mei-Hua, Li, Jia and Hou, Ai-Jun (2015). Diels-Alder adducts with PTP1B inhibition from Morus notabilis. Phytochemistry, 109, 140-146. doi: 10.1016/j.phytochem.2014.10.015

Diels-Alder adducts with PTP1B inhibition from Morus notabilis

2015

Journal Article

Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption

Wang, Hongning, Rong, Xiao, Han, Lu, Tang, Mei, Yu, Meihua, Zhang, Jun, Huang, Weiqiu and Chen, Ruoyu (2015). Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption. RSC Advances, 5 (8), 5695-5703. doi: 10.1039/c4ra12553c

Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption

2014

Other Outputs

Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery

Yu, Meihua (2014). Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery. PhD Thesis, Australian Institute for Bioengineering & Nanotechnology, The University of Queensland. doi: 10.14264/uql.2014.398

Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery

2014

Journal Article

An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery

Yu, Meihua, Niu, Yuting, Yang, Yannan, Hartono, Sandy Budi, Yang, Jie, Huang, Xiaodan, Thorn, Peter and Yu, Chengzhong (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6 (18), 15626-15631. doi: 10.1021/am503060n

An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery

Past funding

  • 2018 - 2022
    A Nano-platform for Affordable and Ultra-sensitive Bio-marker Detection
    ARC Linkage Projects
    Open grant
  • 2018
    Assessment of Novel Nanoadjuvants for the Development of Potent Therapeutic Cancer Vaccines
    UQ Foundation
    Open grant
  • 2018
    Nanotechnology-medicated therapeutic HPV DNA vaccines
    UQ Early Career Researcher
    Open grant
  • 2017 - 2020
    Engineered Spiky Silica Nanoparticles as Effective Immune Adjuvants by Activating Inflammasome and Enhancing Cellular Uptake
    NHMRC Early Career Fellowships
    Open grant
  • 2016
    Advance Queensland Research Fellowship (Early): Nano-pollen encapsulated lysozyme: a safe alternative to antibiotics for livestock
    Advance Queensland Research Fellowships
    Open grant
  • 2012 - 2013
    A general platform technology for functional nanocomposites with advanced applications
    UWA-UQ Bilateral Research Collaboration Award
    Open grant

Availability

Dr Meihua Yu is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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