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Dr Meihua Yu
Dr

Meihua Yu

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Overview

Background

Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.

Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.

Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.

Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).

Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.

Availability

Dr Meihua Yu is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Meihua Yu’s works on UQ eSpace

95 works between 2006 and 2026

41 - 60 of 95 works

2017

Journal Article

Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency

Yang, Yannan, Jambhrunkar, Manasi, Abbaraju, Prasanna Lakshmi, Yu, Meihua, Zhang, Min and Yu, Chengzhong (2017). Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency. Advanced Healthcare Materials, 6 (17) 1700466, 1700466. doi: 10.1002/adhm.201700466

Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency

2017

Journal Article

Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy

Xu, Chun, Lei, Chang, Huang, Lili, Zhang, Jun, Zhang, Hongwei, Song, Hao, Yu, Meihua, Wu, Yeda, Chen, Chen and Yu, Chengzhong (2017). Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy. Chemistry of Materials, 29 (18), 7725-7732. doi: 10.1021/acs.chemmater.7b01804

Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy

2017

Journal Article

Pristine mesoporous carbon hollow spheres as safe adjuvants induce excellent Th2-biased immune response

Jambhrunkar, Manasi, Yu, Meihua, Zhang, Hongwei, Abbaraju, Prasanna, Meka, Anand Kumar, Cavallaro, Antonino, Lu, Yao, Mitter, Neena and Yu, Chengzhong (2017). Pristine mesoporous carbon hollow spheres as safe adjuvants induce excellent Th2-biased immune response. Nano Research, 11 (1), 370-382. doi: 10.1007/s12274-017-1640-1

Pristine mesoporous carbon hollow spheres as safe adjuvants induce excellent Th2-biased immune response

2017

Journal Article

Core-shell-structured dendritic mesoporous silica nanoparticles for combined photodynamic therapy and antibody delivery

Abbaraju, Prasanna Lakshmi, Yang, Yannan, Yu, Meihua, Fu, Jianye, Xu, Chun and Yu, Chengzhong (2017). Core-shell-structured dendritic mesoporous silica nanoparticles for combined photodynamic therapy and antibody delivery. Chemistry - An Asian Journal, 12 (13), 1465-1469. doi: 10.1002/asia.201700392

Core-shell-structured dendritic mesoporous silica nanoparticles for combined photodynamic therapy and antibody delivery

2017

Journal Article

Silica-based nanoparticles for therapeutic protein delivery

Yu, Meihua, Gu, Zhengying, Ottewell, Thomas and Yu, Chengzhong (2017). Silica-based nanoparticles for therapeutic protein delivery. Journal of Materials Chemistry B, 5 (18), 3241-3252. doi: 10.1039/c7tb00244k

Silica-based nanoparticles for therapeutic protein delivery

2017

Journal Article

Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells

Abbaraju, Prasanna Lakshmi, Meka, Anand Kumar, Song, Hao, Yang, Yannan, Jambhrunkar, Manasi, Zhang, Jun, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2017). Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells. Journal of the American Chemical Society, 139 (18), 6321-6328. doi: 10.1021/jacs.6b12622

Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells

2017

Journal Article

Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis

Kalantari, Mohammad, Yu, Meihua, Yang, Yannan, Strounina, Ekaterina, Gu, Zhengying, Huang, Xiaodan, Zhang, Jun, Song, Hao and Yu, Chengzhong (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10 (2), 605-617. doi: 10.1007/s12274-016-1320-6

Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis

2017

Journal Article

Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment

Kalantari, Mohammad, Yu, Meihua, Noonan, Owen, Song, Hao, Xu, Chun, Huang, Xiaodan, Xiang, Feixiang, Wang, Xiaolin and Yu, Chengzhong (2017). Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment. Chemosphere, 166, 109-117. doi: 10.1016/j.chemosphere.2016.09.083

Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment

2017

Journal Article

Elaborate control over the morphology and pore structure of porous silicas for VOCs removal with high efficiency and stability

Wang, Hongning, Wang, Tao, Yu, Meihua, Huang, Xiaodan, Zhong, Jing, Huang, Weiqiu and Chen, Ruoyu (2017). Elaborate control over the morphology and pore structure of porous silicas for VOCs removal with high efficiency and stability. Adsorption, 23 (1), 37-50. doi: 10.1007/s10450-016-9815-8

Elaborate control over the morphology and pore structure of porous silicas for VOCs removal with high efficiency and stability

2016

Journal Article

Structure-dependent and glutathione-responsive biodegradable dendritic mesoporous organosilica nanoparticles for safe protein delivery

Yang, Yannan, Wan, Jingjing, Niu, Yuting, Gu, Zhengying, Zhang, Jun, Yu, Meihua and Yu, Chengzhong (2016). Structure-dependent and glutathione-responsive biodegradable dendritic mesoporous organosilica nanoparticles for safe protein delivery. Chemistry of Materials, 28 (24), 9008-9016. doi: 10.1021/acs.chemmater.6b03896

Structure-dependent and glutathione-responsive biodegradable dendritic mesoporous organosilica nanoparticles for safe protein delivery

2016

Journal Article

A vesicle supra-assembly approach to synthesize amine-functionalized hollow dendritic mesoporous silica nanospheres for protein delivery

Meka, Anand Kumar, Abbaraju, Prasanna Lakshmi, Song, Hao, Xu, Chun, Zhang, Jun, Zhang, Hongwei, Yu, Meihua and Yu, Chengzhong (2016). A vesicle supra-assembly approach to synthesize amine-functionalized hollow dendritic mesoporous silica nanospheres for protein delivery. Small, 12 (37), 5169-5177. doi: 10.1002/smll.201602052

A vesicle supra-assembly approach to synthesize amine-functionalized hollow dendritic mesoporous silica nanospheres for protein delivery

2016

Journal Article

Combination of microporous hollow carbon spheres and nafion for the individual metal-free stripping detectionof Pb2+ and Cd2+

Niu, Xiangheng, Zhang, Hongwei, Yu, Meihua, Zhao, Hongli, Lan, Minbo and Yu, Chengzhong (2016). Combination of microporous hollow carbon spheres and nafion for the individual metal-free stripping detectionof Pb2+ and Cd2+. Analytical Sciences, 32 (9), 943-949. doi: 10.2116/analsci.32.943

Combination of microporous hollow carbon spheres and nafion for the individual metal-free stripping detectionof Pb2+ and Cd2+

2016

Journal Article

Silica nanopollens enhance adhesion for long-term bacterial inhibition

Song, Hao, Ahmad Nor, Yusilawati, Yu, Meihua, Yang, Yannan, Zhang, Jun, Zhang, Hongwei, Xu, Chun, Mitter, Neena and Yu, Chengzhong (2016). Silica nanopollens enhance adhesion for long-term bacterial inhibition. Journal of the Americal Chemical Society, 138 (20), 6455-6462. doi: 10.1021/jacs.6b00243

Silica nanopollens enhance adhesion for long-term bacterial inhibition

2016

Journal Article

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

Wang, Yue, Nor, Yusilawati Ahmad, Song, Hao, Yang, Yannan, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4 (15), 2646-2653. doi: 10.1039/c6tb00053c

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

2016

Journal Article

Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery

Meka, Anand Kumar, Niu, Yuting, Karmakar, Surajit, Hartono, Sandy Budi, Zhang, Jun, Lin, Chun Xiang Cynthia, Zhang, Hongwei, Whittaker, Andrew, Jack, Kevin, Yu, Meihua and Yu, Chengzhong (2016). Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery. ChemNanoMat, 2 (3), 220-225. doi: 10.1002/cnma.201600021

Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery

2016

Journal Article

Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient

Yang, Yannan, Bernardi, Stefano, Song, Hao, Zhang, Jun, Yu, Meihua, Reid, James C., Strounina, Ekaterina, Searles, Debra J. and Yu, Chengzhong (2016). Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient. Chemistry of Materials, 28 (3), 704-707. doi: 10.1021/acs.chemmater.5b03963

Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient

2015

Journal Article

Size-dependent gene delivery of amine-modified silica nanoparticles

Yu, Meihua, Niu, Yuting, Zhang, Jun, Zhang, Hongwei, Yang, Yannan, Taran, Elena, Jambhrunkar, Siddharth, Gu, Wenyi, Thorn, Peter and Yu, Chengzhong (2015). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9 (2), 291-305. doi: 10.1007/s12274-015-0909-5

Size-dependent gene delivery of amine-modified silica nanoparticles

2015

Journal Article

Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery

Niu, Yuting, Yu, Meihua, Meka, Anand, Liu, Yang, Zhang, Jun, Yang, Yannan and Yu, Chengzhong (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4 (2), 212-219. doi: 10.1039/c5tb01911g

Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery

2015

Journal Article

Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery

Xu, Chun, Yu, Meihua, Noonan, Owen, Zhang, Jun, Song, Hao, Zhang, Hongwei, Lei, Chang, Niu, Yuting, Huang, Xiaodan, Yang, Yannan and Yu, Chengzhong (2015). Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery. Small, 11 (44), 5949-5955. doi: 10.1002/smll.201501449

Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery

2015

Journal Article

Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway

Zhang, Hongwei, Yu, Meihua, Song, Hao, Noonan, Owen, Zhang, Jun, Yang, Yannan, Zhou, Liang and Yu, Chengzhong (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27 (18), 6297-6304. doi: 10.1021/acs.chemmater.5b01993

Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway

Funding

Past funding

  • 2018 - 2022
    A Nano-platform for Affordable and Ultra-sensitive Bio-marker Detection
    ARC Linkage Projects
    Open grant
  • 2018
    Assessment of Novel Nanoadjuvants for the Development of Potent Therapeutic Cancer Vaccines
    UQ Foundation
    Open grant
  • 2018
    Nanotechnology-medicated therapeutic HPV DNA vaccines
    UQ Early Career Researcher
    Open grant
  • 2017 - 2020
    Engineered Spiky Silica Nanoparticles as Effective Immune Adjuvants by Activating Inflammasome and Enhancing Cellular Uptake
    NHMRC Early Career Fellowships
    Open grant
  • 2016
    Advance Queensland Research Fellowship (Early): Nano-pollen encapsulated lysozyme: a safe alternative to antibiotics for livestock
    Advance Queensland Research Fellowships
    Open grant
  • 2012 - 2013
    A general platform technology for functional nanocomposites with advanced applications
    UWA-UQ Bilateral Research Collaboration Award
    Open grant

Supervision

Availability

Dr Meihua Yu is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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