Overview
Background
Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.
Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.
Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.
Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).
Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.
Availability
- Dr Meihua Yu is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Meihua Yu’s works on UQ eSpace
2017
Journal Article
Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency
Yang, Yannan, Jambhrunkar, Manasi, Abbaraju, Prasanna Lakshmi, Yu, Meihua, Zhang, Min and Yu, Chengzhong (2017). Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency. Advanced Healthcare Materials, 6 (17) 1700466, 1700466. doi: 10.1002/adhm.201700466
2017
Journal Article
Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy
Xu, Chun, Lei, Chang, Huang, Lili, Zhang, Jun, Zhang, Hongwei, Song, Hao, Yu, Meihua, Wu, Yeda, Chen, Chen and Yu, Chengzhong (2017). Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy. Chemistry of Materials, 29 (18), 7725-7732. doi: 10.1021/acs.chemmater.7b01804
2017
Journal Article
Pristine mesoporous carbon hollow spheres as safe adjuvants induce excellent Th2-biased immune response
Jambhrunkar, Manasi, Yu, Meihua, Zhang, Hongwei, Abbaraju, Prasanna, Meka, Anand Kumar, Cavallaro, Antonino, Lu, Yao, Mitter, Neena and Yu, Chengzhong (2017). Pristine mesoporous carbon hollow spheres as safe adjuvants induce excellent Th2-biased immune response. Nano Research, 11 (1), 370-382. doi: 10.1007/s12274-017-1640-1
2017
Journal Article
Core-shell-structured dendritic mesoporous silica nanoparticles for combined photodynamic therapy and antibody delivery
Abbaraju, Prasanna Lakshmi, Yang, Yannan, Yu, Meihua, Fu, Jianye, Xu, Chun and Yu, Chengzhong (2017). Core-shell-structured dendritic mesoporous silica nanoparticles for combined photodynamic therapy and antibody delivery. Chemistry - An Asian Journal, 12 (13), 1465-1469. doi: 10.1002/asia.201700392
2017
Journal Article
Silica-based nanoparticles for therapeutic protein delivery
Yu, Meihua, Gu, Zhengying, Ottewell, Thomas and Yu, Chengzhong (2017). Silica-based nanoparticles for therapeutic protein delivery. Journal of Materials Chemistry B, 5 (18), 3241-3252. doi: 10.1039/c7tb00244k
2017
Journal Article
Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells
Abbaraju, Prasanna Lakshmi, Meka, Anand Kumar, Song, Hao, Yang, Yannan, Jambhrunkar, Manasi, Zhang, Jun, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2017). Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells. Journal of the American Chemical Society, 139 (18), 6321-6328. doi: 10.1021/jacs.6b12622
2017
Journal Article
Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis
Kalantari, Mohammad, Yu, Meihua, Yang, Yannan, Strounina, Ekaterina, Gu, Zhengying, Huang, Xiaodan, Zhang, Jun, Song, Hao and Yu, Chengzhong (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10 (2), 605-617. doi: 10.1007/s12274-016-1320-6
2017
Journal Article
Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment
Kalantari, Mohammad, Yu, Meihua, Noonan, Owen, Song, Hao, Xu, Chun, Huang, Xiaodan, Xiang, Feixiang, Wang, Xiaolin and Yu, Chengzhong (2017). Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment. Chemosphere, 166, 109-117. doi: 10.1016/j.chemosphere.2016.09.083
2017
Journal Article
Elaborate control over the morphology and pore structure of porous silicas for VOCs removal with high efficiency and stability
Wang, Hongning, Wang, Tao, Yu, Meihua, Huang, Xiaodan, Zhong, Jing, Huang, Weiqiu and Chen, Ruoyu (2017). Elaborate control over the morphology and pore structure of porous silicas for VOCs removal with high efficiency and stability. Adsorption, 23 (1), 37-50. doi: 10.1007/s10450-016-9815-8
2016
Journal Article
Structure-dependent and glutathione-responsive biodegradable dendritic mesoporous organosilica nanoparticles for safe protein delivery
Yang, Yannan, Wan, Jingjing, Niu, Yuting, Gu, Zhengying, Zhang, Jun, Yu, Meihua and Yu, Chengzhong (2016). Structure-dependent and glutathione-responsive biodegradable dendritic mesoporous organosilica nanoparticles for safe protein delivery. Chemistry of Materials, 28 (24), 9008-9016. doi: 10.1021/acs.chemmater.6b03896
2016
Journal Article
A vesicle supra-assembly approach to synthesize amine-functionalized hollow dendritic mesoporous silica nanospheres for protein delivery
Meka, Anand Kumar, Abbaraju, Prasanna Lakshmi, Song, Hao, Xu, Chun, Zhang, Jun, Zhang, Hongwei, Yu, Meihua and Yu, Chengzhong (2016). A vesicle supra-assembly approach to synthesize amine-functionalized hollow dendritic mesoporous silica nanospheres for protein delivery. Small, 12 (37), 5169-5177. doi: 10.1002/smll.201602052
2016
Journal Article
Combination of microporous hollow carbon spheres and nafion for the individual metal-free stripping detectionof Pb2+ and Cd2+
Niu, Xiangheng, Zhang, Hongwei, Yu, Meihua, Zhao, Hongli, Lan, Minbo and Yu, Chengzhong (2016). Combination of microporous hollow carbon spheres and nafion for the individual metal-free stripping detectionof Pb2+ and Cd2+. Analytical Sciences, 32 (9), 943-949. doi: 10.2116/analsci.32.943
2016
Journal Article
Silica nanopollens enhance adhesion for long-term bacterial inhibition
Song, Hao, Ahmad Nor, Yusilawati, Yu, Meihua, Yang, Yannan, Zhang, Jun, Zhang, Hongwei, Xu, Chun, Mitter, Neena and Yu, Chengzhong (2016). Silica nanopollens enhance adhesion for long-term bacterial inhibition. Journal of the Americal Chemical Society, 138 (20), 6455-6462. doi: 10.1021/jacs.6b00243
2016
Journal Article
Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery
Wang, Yue, Nor, Yusilawati Ahmad, Song, Hao, Yang, Yannan, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4 (15), 2646-2653. doi: 10.1039/c6tb00053c
2016
Journal Article
Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery
Meka, Anand Kumar, Niu, Yuting, Karmakar, Surajit, Hartono, Sandy Budi, Zhang, Jun, Lin, Chun Xiang Cynthia, Zhang, Hongwei, Whittaker, Andrew, Jack, Kevin, Yu, Meihua and Yu, Chengzhong (2016). Facile synthesis of large-pore bicontinuous cubic mesoporous silica nanoparticles for intracellular gene delivery. ChemNanoMat, 2 (3), 220-225. doi: 10.1002/cnma.201600021
2016
Journal Article
Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient
Yang, Yannan, Bernardi, Stefano, Song, Hao, Zhang, Jun, Yu, Meihua, Reid, James C., Strounina, Ekaterina, Searles, Debra J. and Yu, Chengzhong (2016). Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient. Chemistry of Materials, 28 (3), 704-707. doi: 10.1021/acs.chemmater.5b03963
2015
Journal Article
Size-dependent gene delivery of amine-modified silica nanoparticles
Yu, Meihua, Niu, Yuting, Zhang, Jun, Zhang, Hongwei, Yang, Yannan, Taran, Elena, Jambhrunkar, Siddharth, Gu, Wenyi, Thorn, Peter and Yu, Chengzhong (2015). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9 (2), 291-305. doi: 10.1007/s12274-015-0909-5
2015
Journal Article
Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery
Niu, Yuting, Yu, Meihua, Meka, Anand, Liu, Yang, Zhang, Jun, Yang, Yannan and Yu, Chengzhong (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4 (2), 212-219. doi: 10.1039/c5tb01911g
2015
Journal Article
Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery
Xu, Chun, Yu, Meihua, Noonan, Owen, Zhang, Jun, Song, Hao, Zhang, Hongwei, Lei, Chang, Niu, Yuting, Huang, Xiaodan, Yang, Yannan and Yu, Chengzhong (2015). Core-cone structured monodispersed mesoporous silica nanoparticles with ultra-large cavity for protein delivery. Small, 11 (44), 5949-5955. doi: 10.1002/smll.201501449
2015
Journal Article
Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway
Zhang, Hongwei, Yu, Meihua, Song, Hao, Noonan, Owen, Zhang, Jun, Yang, Yannan, Zhou, Liang and Yu, Chengzhong (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27 (18), 6297-6304. doi: 10.1021/acs.chemmater.5b01993
Funding
Past funding
Supervision
Availability
- Dr Meihua Yu is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Doctor Philosophy
Development of a Mesoporous Silica Based Nanosystem for Safe and Efficient Therapeutic Delivery
Joint Principal Advisor
Other advisors: Professor Chengzhong Yu
-
2021
Master Philosophy
Development of Silica Based Nanoparticles for Plasmid DNA Delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2020
Doctor Philosophy
Engineered iron-based nanomaterials for macrophage-centred anti-cancer application
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Synthesis and characterization of novel silica nanoparticles for delivery applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Optimised multifunctionality of Mesoporous Carbon Hollow Spheres (MCHS) nanocarriers using carbonization temperature
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Synthesis of Novel Mesoporous Materials as High-performance Adsorbents
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineering Nanomaterials as Safe and Effective Immune Adjuvants
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineered Silica nanoparticles for efficient biomolecules delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2017
Doctor Philosophy
Mesoporous silica nanoparticles for biomedical application
Associate Advisor
Other advisors: Professor Amirali Popat, Professor Chengzhong Yu
-
2016
Doctor Philosophy
Design of Mesoporous Silica Nanoparticles as Drug Carriers
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2016
Master Philosophy
Designed synthesis of large pore mesoporous silica nanoparticles as nano-carriers for bio-applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
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