Overview
Background
Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.
Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.
Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.
Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).
Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.
Availability
- Dr Meihua Yu is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Meihua Yu’s works on UQ eSpace
2015
Journal Article
Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery
Niu, Yuting, Yu, Meihua, Zhang, Jun, Yang, Yannan, Xu, Chun, Yeh, Michael, Taran, Elena, Hou, Jeff Jia Cheng, Gray, Peter P. and Yu, Chengzhong (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3 (43), 8477-8485. doi: 10.1039/c5tb01405k
2015
Journal Article
Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery
Ahmad Nor, Yusilawati, Niu, Yuting, Karmakar, Surajit, Zhou, Liang, Xu, Chun, Zhang, Jun, Zhang, Hongwei, Yu, Meihua, Mahony, Donna, Mitter, Neena, Cooper, Matthew and Yu, Cheng Zhong (2015). Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery. ACS Central Science, 1 (6), 328-334. doi: 10.1021/acscentsci.5b00199
2015
Journal Article
Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway
Gu, Wenyi, Prasadam, Indira, Yu, Meihua, Zhang, Fengxia, Ling, Patrick, Xiao, Yin and Yu, Chengzhong (2015). Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. BMC Cancer, 15 (1) 609, 1-11. doi: 10.1186/s12885-015-1614-1
2015
Journal Article
Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy
Yang, Yannan, Yu, Meihua, Song, Hao, Wang, Yue and Yu, Chengzhong (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7 (28), 11894-11898. doi: 10.1039/c5nr02769a
2015
Journal Article
Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery
Yang, Yannan, Niu, Yuting, Zhang, Jun, Meka, Anand Kumar, Zhang, Hongwei, Xu, Chun, Lin, Chun Xiang Cynthia, Yu, Meihua and Yu, Chengzhong (2015). Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery. Small, 11 (23), 2743-2749. doi: 10.1002/smll.201402779
2015
Journal Article
Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes
Liu, Chao, Yu, Meihua, Li, Yang, Li, Jiansheng, Wang, Jing, Yu, Chengzhong and Wang, Lianjun (2015). Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes. Nanoscale, 7 (27), 11580-11590. doi: 10.1039/c5nr02389k
2015
Journal Article
Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption
Wang, Hongning, Rong, Xiao, Han, Lu, Tang, Mei, Yu, Meihua, Zhang, Jun, Huang, Weiqiu and Chen, Ruoyu (2015). Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption. RSC Advances, 5 (8), 5695-5703. doi: 10.1039/c4ra12553c
2014
Other Outputs
Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery
Yu, Meihua (2014). Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery. PhD Thesis, Australian Institute for Bioengineering & Nanotechnology, The University of Queensland. doi: 10.14264/uql.2014.398
2014
Journal Article
An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery
Yu, Meihua, Niu, Yuting, Yang, Yannan, Hartono, Sandy Budi, Yang, Jie, Huang, Xiaodan, Thorn, Peter and Yu, Chengzhong (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6 (18), 15626-15631. doi: 10.1021/am503060n
2014
Journal Article
Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake
Yang, Yannan, Karmakar, Surajit, Zhang, Jun, Yu, Meihua, Mitter, Neena and Yu, Chengzhong (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2 (30), 4929-4934. doi: 10.1039/c4tb00595c
2014
Journal Article
Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers
Hartono, Sandy B., Yu, Meihua, Gu, Wenyi, Yang, Jie, Strounina, Ekaterina, Wang, Xiaolin, Qiao, Shizhang and Yu, Chengzhong (2014). Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers. Nanotechnology, 25 (5) 055701, 055701.1-055701.13. doi: 10.1088/0957-4484/25/5/055701
2014
Journal Article
Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery
Hartono, Sandy Budi, Phuoc, Nghia Truong, Yu, Meihua, Jia, Zhongfan, Monteiro, Michael J., Qiao, Shizhang and Yu, Chengzhong (2014). Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery. Journal of Materials Chemistry B, 2 (16), 718-726. doi: 10.1039/C3TB21015D
2014
Journal Article
Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids
Yu, Meihua, Karmakar, Surajit, Yang, Jie, Zhang, Hongwei, Yang, Yannan, Thorn, Peter and Yu, Chengzhong (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids. Chemical Communications, 50 (13), 1527-1529. doi: 10.1039/C3CC48416E
2014
Journal Article
Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin
Jambhrunkar, Siddharth, Karmakar, Surajit, Popat, Amirali, Yu, Meihua and Yu, Chengzhong (2014). Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin. RSC Advances, 4 (2), 709-712. doi: 10.1039/c3ra44257h
2014
Journal Article
Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins
Zhang, Jun, Karmakar, Surajit, Yu, Meihua, Mitter, Neena, Zou, Jin and Yu, Chengzhong (2014). Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins. Small, 10 (24), 5068-5076. doi: 10.1002/smll.201401538
2014
Journal Article
Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy
Yang, Yannan, Karmakar, Surajit, Yu, Meihua, Popat, Amirali and Yu, Chengzhong (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, Article in press (3), 316-318. doi: 10.1246/cl.130930
2013
Journal Article
Nanoparticles mimicking viral surface topography for enhanced cellular delivery
Niu, Yuting, Yu, Meihua, Hartono, Sandy B., Yang, Jie, Xu, Hongyi, Zhang, Hongwei, Zhang, Jun, Zou, Jin, Dexter, Annette, Gu, Wenyi and Yu, Chengzhong (2013). Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Advanced Materials, 25 (43), 6233-6237. doi: 10.1002/adma.201302737
2013
Journal Article
High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance
Yang, Jie, Zhang, Hongwei, Yu, Meihua, Emmanuelawati, Irene, Zou, Jin, Yuan, Zhiguo and Yu, Chengzhong (2013). High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance. Advanced Functional Materials, Early View (10), 1-10. doi: 10.1002/adfm.201302561
2013
Journal Article
Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision
Jarnbhrunkar, Siddharth, Yu, Meihua, Yang, Jie, Zhang, Jun, Shrotri, Abhijit, Endo-Munoz, Liliana, Moreau, Joel, Lu, Gaoqing and Yu, Chengzhong (2013). Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision. Journal of the American Chemical Society, 135 (23), 8444-8447. doi: 10.1021/ja402463h
2013
Journal Article
Laser engineered graphene paper for mass spectrometry imaging
Qian, Kun, Zhou, Liang, Liu, Jian, Yang, Jie, Xu, Hongyi, Yu, Meihua, Nouwens, Amanda, Zou, Jin, Monteiro, Michael J. and Yu, Chengzhong (2013). Laser engineered graphene paper for mass spectrometry imaging. Scientific Reports, 3 (1) 1415, 1415.1-1415.7. doi: 10.1038/srep01415
Funding
Past funding
Supervision
Availability
- Dr Meihua Yu is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Completed supervision
-
2019
Doctor Philosophy
Development of a Mesoporous Silica Based Nanosystem for Safe and Efficient Therapeutic Delivery
Joint Principal Advisor
Other advisors: Professor Chengzhong Yu
-
2021
Master Philosophy
Development of Silica Based Nanoparticles for Plasmid DNA Delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2020
Doctor Philosophy
Engineered iron-based nanomaterials for macrophage-centred anti-cancer application
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Synthesis and characterization of novel silica nanoparticles for delivery applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Optimised multifunctionality of Mesoporous Carbon Hollow Spheres (MCHS) nanocarriers using carbonization temperature
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Synthesis of Novel Mesoporous Materials as High-performance Adsorbents
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineering Nanomaterials as Safe and Effective Immune Adjuvants
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineered Silica nanoparticles for efficient biomolecules delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2017
Doctor Philosophy
Mesoporous silica nanoparticles for biomedical application
Associate Advisor
Other advisors: Professor Amirali Popat, Professor Chengzhong Yu
-
2016
Doctor Philosophy
Design of Mesoporous Silica Nanoparticles as Drug Carriers
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2016
Master Philosophy
Designed synthesis of large pore mesoporous silica nanoparticles as nano-carriers for bio-applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
Media
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