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Dr Meihua Yu
Dr

Meihua Yu

Email: 

Overview

Background

Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.

Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.

Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.

Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).

Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.

Availability

Dr Meihua Yu is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Meihua Yu’s works on UQ eSpace

95 works between 2006 and 2026

61 - 80 of 95 works

2015

Journal Article

Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery

Niu, Yuting, Yu, Meihua, Zhang, Jun, Yang, Yannan, Xu, Chun, Yeh, Michael, Taran, Elena, Hou, Jeff Jia Cheng, Gray, Peter P. and Yu, Chengzhong (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3 (43), 8477-8485. doi: 10.1039/c5tb01405k

Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery

2015

Journal Article

Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery

Ahmad Nor, Yusilawati, Niu, Yuting, Karmakar, Surajit, Zhou, Liang, Xu, Chun, Zhang, Jun, Zhang, Hongwei, Yu, Meihua, Mahony, Donna, Mitter, Neena, Cooper, Matthew and Yu, Cheng Zhong (2015). Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery. ACS Central Science, 1 (6), 328-334. doi: 10.1021/acscentsci.5b00199

Shaping nanoparticles with hydrophilic compositions and hydrophobic properties as nanocarriers for antibiotic delivery

2015

Journal Article

Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway

Gu, Wenyi, Prasadam, Indira, Yu, Meihua, Zhang, Fengxia, Ling, Patrick, Xiao, Yin and Yu, Chengzhong (2015). Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. BMC Cancer, 15 (1) 609, 1-11. doi: 10.1186/s12885-015-1614-1

Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway

2015

Journal Article

Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy

Yang, Yannan, Yu, Meihua, Song, Hao, Wang, Yue and Yu, Chengzhong (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7 (28), 11894-11898. doi: 10.1039/c5nr02769a

Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy

2015

Journal Article

Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery

Yang, Yannan, Niu, Yuting, Zhang, Jun, Meka, Anand Kumar, Zhang, Hongwei, Xu, Chun, Lin, Chun Xiang Cynthia, Yu, Meihua and Yu, Chengzhong (2015). Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery. Small, 11 (23), 2743-2749. doi: 10.1002/smll.201402779

Biphasic synthesis of large-pore and well-dispersed benzene bridged mesoporous organosilica nanoparticles for intracellular protein delivery

2015

Journal Article

Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes

Liu, Chao, Yu, Meihua, Li, Yang, Li, Jiansheng, Wang, Jing, Yu, Chengzhong and Wang, Lianjun (2015). Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes. Nanoscale, 7 (27), 11580-11590. doi: 10.1039/c5nr02389k

Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes

2015

Journal Article

Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption

Wang, Hongning, Rong, Xiao, Han, Lu, Tang, Mei, Yu, Meihua, Zhang, Jun, Huang, Weiqiu and Chen, Ruoyu (2015). Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption. RSC Advances, 5 (8), 5695-5703. doi: 10.1039/c4ra12553c

Controlled synthesis of hexagonal mesostructure silica and macroporous ordered siliceous foams for VOCs adsorption

2014

Other Outputs

Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery

Yu, Meihua (2014). Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery. PhD Thesis, Australian Institute for Bioengineering & Nanotechnology, The University of Queensland. doi: 10.14264/uql.2014.398

Designed synthesis of mono-dispersed silica-based nanostructures and their applications in drug/gene delivery

2014

Journal Article

An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery

Yu, Meihua, Niu, Yuting, Yang, Yannan, Hartono, Sandy Budi, Yang, Jie, Huang, Xiaodan, Thorn, Peter and Yu, Chengzhong (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6 (18), 15626-15631. doi: 10.1021/am503060n

An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery

2014

Journal Article

Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake

Yang, Yannan, Karmakar, Surajit, Zhang, Jun, Yu, Meihua, Mitter, Neena and Yu, Chengzhong (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2 (30), 4929-4934. doi: 10.1039/c4tb00595c

Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake

2014

Journal Article

Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers

Hartono, Sandy B., Yu, Meihua, Gu, Wenyi, Yang, Jie, Strounina, Ekaterina, Wang, Xiaolin, Qiao, Shizhang and Yu, Chengzhong (2014). Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers. Nanotechnology, 25 (5) 055701, 055701.1-055701.13. doi: 10.1088/0957-4484/25/5/055701

Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers

2014

Journal Article

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

Hartono, Sandy Budi, Phuoc, Nghia Truong, Yu, Meihua, Jia, Zhongfan, Monteiro, Michael J., Qiao, Shizhang and Yu, Chengzhong (2014). Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery. Journal of Materials Chemistry B, 2 (16), 718-726. doi: 10.1039/C3TB21015D

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

2014

Journal Article

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids

Yu, Meihua, Karmakar, Surajit, Yang, Jie, Zhang, Hongwei, Yang, Yannan, Thorn, Peter and Yu, Chengzhong (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids. Chemical Communications, 50 (13), 1527-1529. doi: 10.1039/C3CC48416E

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids

2014

Journal Article

Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

Jambhrunkar, Siddharth, Karmakar, Surajit, Popat, Amirali, Yu, Meihua and Yu, Chengzhong (2014). Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin. RSC Advances, 4 (2), 709-712. doi: 10.1039/c3ra44257h

Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

2014

Journal Article

Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins

Zhang, Jun, Karmakar, Surajit, Yu, Meihua, Mitter, Neena, Zou, Jin and Yu, Chengzhong (2014). Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins. Small, 10 (24), 5068-5076. doi: 10.1002/smll.201401538

Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins

2014

Journal Article

Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy

Yang, Yannan, Karmakar, Surajit, Yu, Meihua, Popat, Amirali and Yu, Chengzhong (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, Article in press (3), 316-318. doi: 10.1246/cl.130930

Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy

2013

Journal Article

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Niu, Yuting, Yu, Meihua, Hartono, Sandy B., Yang, Jie, Xu, Hongyi, Zhang, Hongwei, Zhang, Jun, Zou, Jin, Dexter, Annette, Gu, Wenyi and Yu, Chengzhong (2013). Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Advanced Materials, 25 (43), 6233-6237. doi: 10.1002/adma.201302737

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

2013

Journal Article

High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance

Yang, Jie, Zhang, Hongwei, Yu, Meihua, Emmanuelawati, Irene, Zou, Jin, Yuan, Zhiguo and Yu, Chengzhong (2013). High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance. Advanced Functional Materials, Early View (10), 1-10. doi: 10.1002/adfm.201302561

High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance

2013

Journal Article

Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision

Jarnbhrunkar, Siddharth, Yu, Meihua, Yang, Jie, Zhang, Jun, Shrotri, Abhijit, Endo-Munoz, Liliana, Moreau, Joel, Lu, Gaoqing and Yu, Chengzhong (2013). Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision. Journal of the American Chemical Society, 135 (23), 8444-8447. doi: 10.1021/ja402463h

Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision

2013

Journal Article

Laser engineered graphene paper for mass spectrometry imaging

Qian, Kun, Zhou, Liang, Liu, Jian, Yang, Jie, Xu, Hongyi, Yu, Meihua, Nouwens, Amanda, Zou, Jin, Monteiro, Michael J. and Yu, Chengzhong (2013). Laser engineered graphene paper for mass spectrometry imaging. Scientific Reports, 3 (1) 1415, 1415.1-1415.7. doi: 10.1038/srep01415

Laser engineered graphene paper for mass spectrometry imaging

Funding

Past funding

  • 2018 - 2022
    A Nano-platform for Affordable and Ultra-sensitive Bio-marker Detection
    ARC Linkage Projects
    Open grant
  • 2018
    Assessment of Novel Nanoadjuvants for the Development of Potent Therapeutic Cancer Vaccines
    UQ Foundation
    Open grant
  • 2018
    Nanotechnology-medicated therapeutic HPV DNA vaccines
    UQ Early Career Researcher
    Open grant
  • 2017 - 2020
    Engineered Spiky Silica Nanoparticles as Effective Immune Adjuvants by Activating Inflammasome and Enhancing Cellular Uptake
    NHMRC Early Career Fellowships
    Open grant
  • 2016
    Advance Queensland Research Fellowship (Early): Nano-pollen encapsulated lysozyme: a safe alternative to antibiotics for livestock
    Advance Queensland Research Fellowships
    Open grant
  • 2012 - 2013
    A general platform technology for functional nanocomposites with advanced applications
    UWA-UQ Bilateral Research Collaboration Award
    Open grant

Supervision

Availability

Dr Meihua Yu is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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