Overview
Background
Dr Meihua Yu is a Research Fellow in Cancer Immunotherapy at the Australian Institute for Bioengineering and Nanotechnology (AIBN). She received her PhD in Biomedical Engineering from AIBN, UQ in 2014. Throughout her research career, she has held full-time research positions from 2014 to 2021 at UQ following completion of her PhD, followed by a position as Research-Teaching Associate Prof at Shanghai University, China (2021-2025). She returned to AIBN in 2026 to continue her research program.
Dr Yu's current research focuses on materials-immunology for cancer treatment and prevention of infectious diseases. Dr Yu has published 95 papers (H-index, 40) in top international journals including Science Advances, Angewandte Chemie International Edition, Advanced Materials, Journal of the American Chemical Society, Journal of Immunology, and Chemical Society Reviews. Her innovative research has resulted in 1 international patents and 14 Chinese patents.
Dr Yu has secured competitive research funding over $1.0M from the ARC, NHMRC, Queensland Government, National Natural Science Foundation of China, Shanghai Municipality, and Zhejiang Province (e.g., UQ Early Career grants, ARC Linkage projects, Queensland Biomedical Assistance Fund, and the 2017 UQ Foundation Research Excellence Award).
Dr Yu has been awarded four prestigious national and state fellowships, including 2017 NHMRC Early Career Fellowship, 2016 Advance Queensland Early Career Research Fellowship, 2021 Shanghai Excellent Overseas Young Scientists, and 2022 Zhejiang Overseas Thousand Talents Program (relinquished). She has actively pursued commercial translation of her discoveries through strategic collaborations with industry partners, including Ridley, Ellume, and Jingang Medicines.
Dr Yu serves as an invited reviewer for national competitive grants and manuscripts for more than 40 international journals, including Med, ACS Nano, and Advanced Materials.
Availability
- Dr Meihua Yu is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Meihua Yu’s works on UQ eSpace
2023
Journal Article
Regulation of antigen-specific immunotherapy with nanomaterials
Ye, Weifan, Jia, Yiwen, Ren, Hongze, Xie, Yujie, Yu, Meihua and Chen, Yu (2023). Regulation of antigen-specific immunotherapy with nanomaterials. Advanced NanoBiomed Research, 3 (12) 2300068, 1-21. doi: 10.1002/anbr.202300068
2023
Journal Article
Engineering advanced nanomedicines against central nervous system diseases
Shi, Shuyu, Ren, Hongze, Xie, Yujie, Yu, Meihua, Chen, Yu and Yang, Liqun (2023). Engineering advanced nanomedicines against central nervous system diseases. Materials Today, 69, 355-392. doi: 10.1016/j.mattod.2023.08.005
2023
Journal Article
Emerging nano-immunotherapeutic approaches to glioma
Nan, Jin, Yang, Wei, Xie, Yujie, Yu, Meihua, Chen, Yu and Zhang, Jun (2023). Emerging nano-immunotherapeutic approaches to glioma. Small Structures, 4 (8) 2300016. doi: 10.1002/sstr.202300016
2023
Journal Article
Adjuvant physiochemistry and advanced nanotechnology for vaccine development
Ren, Hongze, Jia, Wencong, Xie, Yujie, Yu, Meihua and Chen, Yu (2023). Adjuvant physiochemistry and advanced nanotechnology for vaccine development. Chemical Society Reviews, 52 (15), 5172-5254. doi: 10.1039/d2cs00848c
2023
Journal Article
Nanoformulations targeting immune cells for cancer therapy: mRNA therapeutics
Yang, Wei, Cao, Jianwei, Cheng, Hui, Chen, Liang, Yu, Meihua, Chen, Yu and Cui, Xingang (2023). Nanoformulations targeting immune cells for cancer therapy: mRNA therapeutics. Bioactive Materials, 23, 438-470. doi: 10.1016/j.bioactmat.2022.11.014
2022
Journal Article
Targeted cancer immunotherapy: nanoformulation engineering and clinical translation
Yu, Meihua, Yang, Wei, Yue, Wenwen and Chen, Yu (2022). Targeted cancer immunotherapy: nanoformulation engineering and clinical translation. Advanced Science, 9 (35) 2204335, 1-37. doi: 10.1002/advs.202204335
2022
Journal Article
Nanomedicine enables efficient CRISPR-Cas9 genome editing for disease treatment
Ma, Lifang, Dong, Caihong, Yu, Meihua, Song, Xinran, Yu, Yongchun and Chen, Yu (2022). Nanomedicine enables efficient CRISPR-Cas9 genome editing for disease treatment. Science Bulletin, 67 (6), 572-576. doi: 10.1016/j.scib.2021.11.016
2021
Journal Article
Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq
Rødahl, Inga, Gotley, James, Andersen, Stacey B., Yu, Meihua, Mehdi, Ahmed M., Christ, Angelika N., Hamilton-Williams, Emma E., Frazer, Ian H., Lukowski, Samuel W. and Chandra, Janin (2021). Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq. STAR Protocols, 2 (4) 100842, 1-27. doi: 10.1016/j.xpro.2021.100842
2021
Journal Article
Editorial: Enhancing drug delivery and tumor penetration
Tang, Yuxia, Yu, Meihua, Su, Xiaodan, Teng, Zhaogang and Wang, Shouju (2021). Editorial: Enhancing drug delivery and tumor penetration. Frontiers in Oncology, 11 775001, 775001. doi: 10.3389/fonc.2021.775001
2021
Journal Article
Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells
Lukowski, Samuel W., Rodahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H. and Chandra, Janin (2021). Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells. iScience, 24 (5) 102402, 1-21. doi: 10.1016/j.isci.2021.102402
2021
Journal Article
Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients
Budhwani, Megha, Turrell, Gavin, Yu, Meihua, Frazer, Ian H., Mehdi, Ahmed M. and Chandra, Janin (2021). Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients. Frontiers in Molecular Biosciences, 8 622643, 622643. doi: 10.3389/fmolb.2021.622643
2021
Journal Article
Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy
Chandra, Janin, Teoh, Siok Min, Kuo, Paula, Tolley, Lynn, Bashaw, Abate Assefa, Tuong, Zewen Kelvin, Liu, Yang, Chen, Zibin, Wells, James W., Yu, Chengzhong, Frazer, Ian H. and Yu, Meihua (2021). Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy. The Journal of Immunology, 206 (5), ji2000355-998. doi: 10.4049/jimmunol.2000355
2021
Journal Article
Rambutan-like silica nanoparticles at tailored particle sizes for plasmid DNA delivery
Hines, Elizabeth, Cheng, Dan, Wu, Weixi, Yu, Meihua, Xu, Chun, Song, Hao and Yu, Chengzhong (2021). Rambutan-like silica nanoparticles at tailored particle sizes for plasmid DNA delivery. Journal of Materials Science, 56 (9), 5830-5844. doi: 10.1007/s10853-020-05660-w
2021
Book Chapter
Therapeutic DNA Vaccine Against HPV16-Associated Cancer
Yu, Meihua and Chandra, Janin (2021). Therapeutic DNA Vaccine Against HPV16-Associated Cancer. DNA Vaccines. (pp. 241-252) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0872-2_13
2020
Journal Article
Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epithelium
Bashaw, Abate Assefa, Zhou, Chenhao, Yu, Meihua, Tolley, Lynn, Leggatt, Graham R., Frazer, Ian H. and Chandra, Janin (2020). Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epithelium. The Journal of Investigative Dermatology, 141 (5), 1264-1273.e3. doi: 10.1016/j.jid.2020.10.011
2020
Journal Article
Sequential PDT and PTT using dual-modal single-walled carbon nanohorns synergistically promote systemic immune responses against tumor metastasis and relapse
Yang, Jingxing, Hou, Mengfei, Sun, Wenshe, Wu, Qinghe, Xu, Jia, Xiong, Liqin, Chai, Yimin, Liu, Yuxin, Yu, Meihua, Wang, Haolu, Xu, Zhi Ping, Liang, Xiaowen and Zhang, Chunfu (2020). Sequential PDT and PTT using dual-modal single-walled carbon nanohorns synergistically promote systemic immune responses against tumor metastasis and relapse. Advanced Science, 7 (16) 2001088, 2001088. doi: 10.1002/advs.202001088
2020
Journal Article
Pristine large pore benzene-bridged mesoporous organosilica nanoparticles as an adjuvant and co-delivery platform for eliciting potent antitumor immunity
Jambhrunkar, M., Yang, Y., Yu, M., Zhang, M., Abbaraju, P. L., Ghosh, T., Kalantari, M., Wang, Y., McMillan, N. A. J. and Yu, C. (2020). Pristine large pore benzene-bridged mesoporous organosilica nanoparticles as an adjuvant and co-delivery platform for eliciting potent antitumor immunity. Materials Today Advances, 6 100069, 100069. doi: 10.1016/j.mtadv.2020.100069
2019
Journal Article
Engineering mesoporous silica microspheres as hyper-activation supports for continuous enzymatic biodiesel production
Kalantari, Mohammad, Yu, Meihua, Liu, Yang, Huang, Xiaodan and Yu, Chengzhong (2019). Engineering mesoporous silica microspheres as hyper-activation supports for continuous enzymatic biodiesel production. Materials Chemistry Frontiers, 3 (9), 1816-1822. doi: 10.1039/c9qm00375d
2018
Journal Article
Mesoporous carbon hollow spheres: carbonisation-temperature-dependent delivery of therapeutic proteins
Ghosh, Trisha, Mantri, Manasi, Gu, Zhengying, Kalantari, Mohammad, Yu, Meihua and Yu, Chengzhong (2018). Mesoporous carbon hollow spheres: carbonisation-temperature-dependent delivery of therapeutic proteins. Journal of Materials Chemistry B, 6 (5), 763-768. doi: 10.1039/c7tb02836a
2018
Journal Article
Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance
Wang, Yue, Song, Hao, Yu, Meihua, Xu, Chun, Liu, Yang, Tang, Jie, Yang, Yannan and Yu, Chengzhong (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6 (24), 4089-4095. doi: 10.1039/c8tb00544c
Funding
Past funding
Supervision
Availability
- Dr Meihua Yu is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Doctor Philosophy
Development of a Mesoporous Silica Based Nanosystem for Safe and Efficient Therapeutic Delivery
Joint Principal Advisor
Other advisors: Professor Chengzhong Yu
-
2021
Master Philosophy
Development of Silica Based Nanoparticles for Plasmid DNA Delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2020
Doctor Philosophy
Engineered iron-based nanomaterials for macrophage-centred anti-cancer application
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Synthesis and characterization of novel silica nanoparticles for delivery applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Optimised multifunctionality of Mesoporous Carbon Hollow Spheres (MCHS) nanocarriers using carbonization temperature
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Synthesis of Novel Mesoporous Materials as High-performance Adsorbents
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineering Nanomaterials as Safe and Effective Immune Adjuvants
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineered Silica nanoparticles for efficient biomolecules delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2017
Doctor Philosophy
Mesoporous silica nanoparticles for biomedical application
Associate Advisor
Other advisors: Professor Amirali Popat, Professor Chengzhong Yu
-
2016
Doctor Philosophy
Design of Mesoporous Silica Nanoparticles as Drug Carriers
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2016
Master Philosophy
Designed synthesis of large pore mesoporous silica nanoparticles as nano-carriers for bio-applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
Media
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