Overview
Background
Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.
Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.
Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.
Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).
Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.
Availability
- Dr Meihua Yu is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Meihua Yu’s works on UQ eSpace
2026
Journal Article
Self-Assembled Metal-Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis
Centurion, Franco, Zhang, Xiuwen, Dai, Chen, Kundi, Varun, Kumar, Priyank, Yu, Meihua, Appadoo, Dominique, Rawal, Aditya, Misra, Ashish, Patel, Sanjay, Chen, Yu and Gu, Zi (2026). Self-Assembled Metal-Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis. Angewandte Chemie-International Edition, 65 (7) PMID 370543. doi: 10.1002/anie.202514547
2025
Journal Article
Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment
Nan, Jin, Xia, Chundongqiu, Zhang, Jingyi, Xie, Yujie, Shi, Shuyu, Yang, Wei, Yu, Meihua, Chen, Yu and Zhang, Jun (2025). Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment. Biomaterials, 322 123379, 1-14. doi: 10.1016/j.biomaterials.2025.123379
2025
Journal Article
Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination
Zhu, Anqi, Ren, Hongze, Li, Xiaolong, Yang, Wei, Han, Xiaoxia, Hou, Xiaodong, Zhang, Shen, Li, Shaoyue, Xie, Yujie, Yu, Meihua, Chen, Yu and Xu, Huixiong (2025). Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination. Nano Today, 61 102590. doi: 10.1016/j.nantod.2024.102590
2025
Journal Article
DNA origami-based composite nanosandwich for iteratively potentiated chemo-immunotherapy
Li, Mengyue, Zhang, Hanxi, Xiong, Peizheng, He, Yuhan, Zhou, Wanyi, Wu, Chunhui, Liao, Xiaoling, Zhang, Wei, Yang, Hong and Liu, Yiyao (2025). DNA origami-based composite nanosandwich for iteratively potentiated chemo-immunotherapy. Journal of Controlled Release, 379, 452-465. doi: 10.1016/j.jconrel.2025.01.031
2025
Journal Article
Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation
Jia, Wencong, Wu, Ye, Xie, Yujie, Yu, Meihua and Chen, Yu (2025). Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation. Advanced Materials, 37 (8) 2413603, 1-70. doi: 10.1002/adma.202413603
2025
Journal Article
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor
Yang, Wei, Di, Sichen, Yang, Zihuan, Cao, Jianwei, Fu, Qingqiao, Ren, Hongze, Cheng, Hui, Xie, Yujie, Jia, Wencong, Dai, Xinyue, Yu, Meihua, Chen, Yu and Cui, Xingang (2025). One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor. Science Advances, 11 (5) eado7373, 1-23. doi: 10.1126/sciadv.ado7373
2025
Journal Article
A digital twin system for rock triaxial mechanical tests incorporating probabilistic parameter updates and model prediction through data assimilation technique
Lyu, Changhao, Xu, Weiya, Wang, Haijiang, Wu, Yizhe and Wang, Huanling (2025). A digital twin system for rock triaxial mechanical tests incorporating probabilistic parameter updates and model prediction through data assimilation technique. Rock Mechanics and Rock Engineering, 58 (5), 5845-5860. doi: 10.1007/s00603-025-04406-x
2025
Journal Article
Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment
Wang, Huijing, He, Wenjin, Liao, Jing, Wang, Shuangshuang, Dai, Xinyue, Yu, Meihua, Xie, Yujie and Chen, Yu (2025). Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment. Advanced Materials, 37 (1) 2411967, 1-47. doi: 10.1002/adma.202411967
2025
Journal Article
External stimuli-driven catalytic hydrogels for biomedical applications
Liao, Jing, Sun, Jijun, Jia, Wencong, He, Wenjin, Wang, Huijing, Huang, Weiyun, Wang, Yanmei, Yu, Meihua, Xie, Yujie and Chen, Yu (2025). External stimuli-driven catalytic hydrogels for biomedical applications. Chemical Communications, 61 (20), 3946-3966. doi: 10.1039/d4cc05256k
2024
Journal Article
Deterioration mechanism and statistical damage constitutive model of red-bed soft rock with different moisture content
Wu, Yizhe, Wang, Huanling, Zhang, Yanjie, Lyu, Changhao, Liu, Yuxuan and Wang, Wenxiu (2024). Deterioration mechanism and statistical damage constitutive model of red-bed soft rock with different moisture content. Pure and Applied Geophysics, 182 (1), 189-208. doi: 10.1007/s00024-024-03609-7
2024
Journal Article
R(3780) resonance interpreted as the 13D1-wave dominant state of charmonium from precise measurements of the cross section of e+ e- → hadrons
Ablikim, M., Achasov, M. N., Adlarson, P., Ai, X. C., Aliberti, R., Amoroso, A., An, M. R., An, Q., Bai, Y., Bakina, O., Balossino, I., Ban, Y., Batozskaya, V., Begzsuren, K., Berger, N., Berlowski, M., Bertani, M., Bettoni, D., Bianchi, F., Bianco, E., Bloms, J., Bortone, A., Boyko, I., Briere, R. A., Brueggemann, A., Cai, H., Cai, X., Calcaterra, A., Cao, G. F. ... Zu, J. (2024). R(3780) resonance interpreted as the 13D1-wave dominant state of charmonium from precise measurements of the cross section of e+ e- → hadrons. Physical Review Letters, 133 (24) 241902, 1-10. doi: 10.1103/PhysRevLett.133.241902
2024
Journal Article
STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines
Jia, Wencong, Chandra, Janin, Teoh, Siok Min, Tolley, Lynn, Yang, Haotian, Tse, Brian W. C., Sokolowski, Kamil A., Liang, Xiaowen, Crawford, Darrell H. G., Steel, Jason C., Yu, Chengzhong, Roberts, Michael S., Frazer, Ian H., Chen, Yu, Wang, Haolu and Yu, Meihua (2024). STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines. Nano Letters, 24 (49), 1-10. doi: 10.1021/acs.nanolett.4c03846
2024
Journal Article
Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasu's arteritis
Fang, Chenglong, Du, Lihong, Gao, Shang, Chen, Yuexin, Chen, Zuoguan, Wu, Zhiyuan, Li, Lili, Li, Jing, Zeng, Xiaofeng, Li, Mengtao, Li, Yongjun and Tian, Xinping (2024). Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasu's arteritis. Annals of the Rheumatic Diseases, 83 (11), 1522-1535. doi: 10.1136/ard-2024-225630
2024
Conference Publication
Angiography-Derived Radial Wall Strain Predicts Efficacy of Drug-Coated Balloon Angioplasty for De Novo Small Vessel Disease: Insights From the PEPCAD China SVD Study
Xu, Ke, Fu, Xi, Wu, Yizhe, Wang, Zhiqing, Chu, Miao, Qian, Juying, He, Ben, Tu, Shengxian, Shen, Linghong and Ge, Junbo (2024). Angiography-Derived Radial Wall Strain Predicts Efficacy of Drug-Coated Balloon Angioplasty for De Novo Small Vessel Disease: Insights From the PEPCAD China SVD Study. 36th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Washington Dc, Oct 27-30, 2024. NEW YORK: ELSEVIER SCIENCE INC.
2024
Conference Publication
Five-Year Clinical Outcomes of Patients Treated With the Xinsorb Bioresorbable Sirolimus-Eluting Scaffolds
Yin, Jiasheng, Xu, Qiang, Wu, Yizhe, Chen, Jiahui, Shen, Li, Qian, Juying, Ge, Lei and Ge, Junbo (2024). Five-Year Clinical Outcomes of Patients Treated With the Xinsorb Bioresorbable Sirolimus-Eluting Scaffolds. 36th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Washington Dc, Oct 27-30, 2024. NEW YORK: ELSEVIER SCIENCE INC.
2024
Conference Publication
Multi-omics integration analysis identifies pathogenic candidate genes of congenital heart defects with vascular malformation
Ding, X. W., Huang, J. X., Chen, Y. H., Li, Z. Y., Wu, Y. Z., Qian, Z. L., Feng, W. Q., Li, Y. R., Zhao, L. D., Zhao, P. J., Lu, Y. N. and Yu, Y. (2024). Multi-omics integration analysis identifies pathogenic candidate genes of congenital heart defects with vascular malformation. European-Society-of-Cardiology Congress (ESC), London England, Aug 30-Sep 02, 2024. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/eurheartj/ehae666.2109
2024
Journal Article
2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor
Ren, Hongze, Zhu, Anqi, Yang, Wei, Jia, Yiwen, Cheng, Hui, Wu, Ye, Tang, Zhengqi, Ye, Weifan, Sun, Mayu, Xie, Yujie, Yu, Meihua and Chen, Yu (2024). 2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor. Advanced Science, 11 (40) 2405729. doi: 10.1002/advs.202405729
2024
Journal Article
Study of the decay and production properties of Ds1 (2536) and Ds2* (2573)
Ablikim, M., Achasov, M. N., Adlarson, P., Afedulidis, O., Ai, X. C., Aliberti, R., Amoroso, A., An, Q., Bai, Y., Bakina, O., Balossino, I., Ban, Y., Bao, H. -R., Batozskay, V., Begzsuren, K., Berger, N., Berlowski, M., Bertani, M., Bettoni, D., Bianchi, F., Bianco, E., Bortone, A., Boyko, I., Briere, R. A., Brueggemann, A., Cai, H., Cai, X., Calcaterra, A., Cao, G. F. ... Zu, J. (2024). Study of the decay and production properties of Ds1 (2536) and Ds2* (2573). Physical Review Letters, 133 (17) 171903, 1-10. doi: 10.1103/PhysRevLett.133.171903
2024
Journal Article
Search for the exclusive W boson hadronic decays W± → π±γ, W± → K±γ and W± → ρ±γ with the ATLAS Detector
Aad, G., Abbott, B., Abeling, K., Abicht, N. J., Abidi, S. H., Aboulhorma, A., Abramowicz, H., Abreu, H., Abulaiti, Y., Acharya, B. S., Bourdarios, C. Adam, Adamczyk, L., Addepalli, S. V., Addison, M. J., Adelman, J., Adiguzel, A., Adye, T., Affolder, A. A., Afik, Y., Agaras, M. N., Agarwala, J., Aggarwal, A., Agheorghiesei, C., Ahmad, A., Ahmadov, F., Ahmed, W. S., Ahuja, S., Ai, X., Aielli, G. ... Zwalinski, L. (2024). Search for the exclusive W boson hadronic decays W± → π±γ, W± → K±γ and W± → ρ±γ with the ATLAS Detector. Physical Review Letters, 133 (16) 161804, 1-23. doi: 10.1103/PhysRevLett.133.161804
2024
Journal Article
Hydrogen sulphide reduces renal ischemia-reperfusion injury by enhancing autophagy and reducing oxidative stress
Li, Hui, Wang, Shuaiwei, An, Shuangshuang, Gao, Biao, Wu, Dongdong and Li, Yanzhang (2024). Hydrogen sulphide reduces renal ischemia-reperfusion injury by enhancing autophagy and reducing oxidative stress. Nephrology, 29 (10), 645-654. doi: 10.1111/nep.14368
Funding
Past funding
Supervision
Availability
- Dr Meihua Yu is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Doctor Philosophy
Development of a Mesoporous Silica Based Nanosystem for Safe and Efficient Therapeutic Delivery
Joint Principal Advisor
Other advisors: Professor Chengzhong Yu
-
2021
Master Philosophy
Development of Silica Based Nanoparticles for Plasmid DNA Delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2020
Doctor Philosophy
Engineered iron-based nanomaterials for macrophage-centred anti-cancer application
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Synthesis and characterization of novel silica nanoparticles for delivery applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Optimised multifunctionality of Mesoporous Carbon Hollow Spheres (MCHS) nanocarriers using carbonization temperature
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Synthesis of Novel Mesoporous Materials as High-performance Adsorbents
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineering Nanomaterials as Safe and Effective Immune Adjuvants
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineered Silica nanoparticles for efficient biomolecules delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2017
Doctor Philosophy
Mesoporous silica nanoparticles for biomedical application
Associate Advisor
Other advisors: Professor Amirali Popat, Professor Chengzhong Yu
-
2016
Doctor Philosophy
Design of Mesoporous Silica Nanoparticles as Drug Carriers
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2016
Master Philosophy
Designed synthesis of large pore mesoporous silica nanoparticles as nano-carriers for bio-applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
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