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Dr Meihua Yu
Dr

Meihua Yu

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Overview

Background

Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.

Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.

Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.

Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).

Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.

Availability

Dr Meihua Yu is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Meihua Yu’s works on UQ eSpace

154 works between 2006 and 2026

121 - 140 of 154 works

2014

Journal Article

Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake

Yang, Yannan, Karmakar, Surajit, Zhang, Jun, Yu, Meihua, Mitter, Neena and Yu, Chengzhong (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2 (30), 4929-4934. doi: 10.1039/c4tb00595c

Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake

2014

Journal Article

Comparative genetic mapping and genomic region collinearity analysis of the powdery mildew resistance gene <i>Pm41</i>

Wang, Zhenzhong, Cui, Yu, Chen, Yongxing, Zhang, Deyun, Liang, Yong, Zhang, Dong, Wu, Qiuhong, Xie, Jingzhong, Ouyang, Shuhong, Li, Delin, Huang, Yinlian, Lu, Ping, Wang, Guoxin, Yu, Meihua, Zhou, Shenghui, Sun, Qixin and Liu, Zhiyong (2014). Comparative genetic mapping and genomic region collinearity analysis of the powdery mildew resistance gene Pm41. Theoretical and Applied Genetics, 127 (8), 1741-1751. doi: 10.1007/s00122-014-2336-5

Comparative genetic mapping and genomic region collinearity analysis of the powdery mildew resistance gene <i>Pm41</i>

2014

Journal Article

Novel grayanane diterpenoids from Rhododendron principis

Liu, Chang-Chang, Lei, Chun, Zhong, Yang, Gao, Li-Xin, Li, Jing-Ya, Yu, Mei-Hua, Li, Jia and Hou, Ai-Jun (2014). Novel grayanane diterpenoids from Rhododendron principis. Tetrahedron, 70 (29), 4317-4322. doi: 10.1016/j.tet.2014.05.019

Novel grayanane diterpenoids from Rhododendron principis

2014

Journal Article

Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers

Hartono, Sandy B., Yu, Meihua, Gu, Wenyi, Yang, Jie, Strounina, Ekaterina, Wang, Xiaolin, Qiao, Shizhang and Yu, Chengzhong (2014). Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers. Nanotechnology, 25 (5) 055701, 055701.1-055701.13. doi: 10.1088/0957-4484/25/5/055701

Synthesis of multi-functional large pore mesoporous silica nanoparticles as gene carriers

2014

Journal Article

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids

Yu, Meihua, Karmakar, Surajit, Yang, Jie, Zhang, Hongwei, Yang, Yannan, Thorn, Peter and Yu, Chengzhong (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids. Chemical Communications, 50 (13), 1527-1529. doi: 10.1039/C3CC48416E

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration of 3D glioma spheroids

2014

Journal Article

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

Hartono, Sandy Budi, Phuoc, Nghia Truong, Yu, Meihua, Jia, Zhongfan, Monteiro, Michael J., Qiao, Shizhang and Yu, Chengzhong (2014). Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery. Journal of Materials Chemistry B, 2 (16), 718-726. doi: 10.1039/C3TB21015D

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

2014

Journal Article

Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

Jambhrunkar, Siddharth, Karmakar, Surajit, Popat, Amirali, Yu, Meihua and Yu, Chengzhong (2014). Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin. RSC Advances, 4 (2), 709-712. doi: 10.1039/c3ra44257h

Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

2014

Journal Article

Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins

Zhang, Jun, Karmakar, Surajit, Yu, Meihua, Mitter, Neena, Zou, Jin and Yu, Chengzhong (2014). Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins. Small, 10 (24), 5068-5076. doi: 10.1002/smll.201401538

Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins

2014

Journal Article

Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy

Yang, Yannan, Karmakar, Surajit, Yu, Meihua, Popat, Amirali and Yu, Chengzhong (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, Article in press (3), 316-318. doi: 10.1246/cl.130930

Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy

2013

Journal Article

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Niu, Yuting, Yu, Meihua, Hartono, Sandy B., Yang, Jie, Xu, Hongyi, Zhang, Hongwei, Zhang, Jun, Zou, Jin, Dexter, Annette, Gu, Wenyi and Yu, Chengzhong (2013). Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Advanced Materials, 25 (43), 6233-6237. doi: 10.1002/adma.201302737

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

2013

Journal Article

High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance

Yang, Jie, Zhang, Hongwei, Yu, Meihua, Emmanuelawati, Irene, Zou, Jin, Yuan, Zhiguo and Yu, Chengzhong (2013). High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance. Advanced Functional Materials, Early View (10), 1-10. doi: 10.1002/adfm.201302561

High-content, well-dispersed gamma-Fe2O3 nanoparticles encapsulated in macroporous silica with superior arsenic removal performance

2013

Journal Article

Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision

Jarnbhrunkar, Siddharth, Yu, Meihua, Yang, Jie, Zhang, Jun, Shrotri, Abhijit, Endo-Munoz, Liliana, Moreau, Joel, Lu, Gaoqing and Yu, Chengzhong (2013). Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision. Journal of the American Chemical Society, 135 (23), 8444-8447. doi: 10.1021/ja402463h

Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision

2013

Journal Article

Laser engineered graphene paper for mass spectrometry imaging

Qian, Kun, Zhou, Liang, Liu, Jian, Yang, Jie, Xu, Hongyi, Yu, Meihua, Nouwens, Amanda, Zou, Jin, Monteiro, Michael J. and Yu, Chengzhong (2013). Laser engineered graphene paper for mass spectrometry imaging. Scientific Reports, 3 (1) 1415, 1415.1-1415.7. doi: 10.1038/srep01415

Laser engineered graphene paper for mass spectrometry imaging

2013

Journal Article

Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells

Yu, Meihua, Jambhrunkar, Siddharth, Thorn, Peter, Chen, Jiezhong, Gu, Wenyi and Yu, Chengzhong (2013). Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells. Nanoscale, 5 (1), 178-183. doi: 10.1039/c2nr32145a

Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells

2012

Journal Article

Recent advance in silica-based engineered nanoparticles for gene therapy

Niu, Yuting, Popat, Amirali, Yu, Meihua, Karmakar, Surajit, Gu, Wenyi and Yu, Chengzhong (2012). Recent advance in silica-based engineered nanoparticles for gene therapy. Therapeutic Delivery, 3 (10), 1217-1237. doi: 10.4155/tde.12.98

Recent advance in silica-based engineered nanoparticles for gene therapy

2012

Journal Article

A simple approach to prepare monodisperse mesoporous silica nanospheres with adjustable sizes

Yu, Meihua, Zhou, Liang, Zhang, Jun, Yuan, Pei, Thorn, Peter, Gu, Wenyi and Yu, Chengzhong (2012). A simple approach to prepare monodisperse mesoporous silica nanospheres with adjustable sizes. Journal of Colloid and Interface Science, 376 (1), 67-75. doi: 10.1016/j.jcis.2012.03.014

A simple approach to prepare monodisperse mesoporous silica nanospheres with adjustable sizes

2012

Journal Article

Overexpression of cGMP-dependent protein kinase I (PKG-I) attenuates ischemia-reperfusion-induced kidney injury

Li, Yanzhang, Tong, Xiaopeng, Maimaitiyiming, Hasiyeti, Clemons, Kate, Cao, Ji-Min and Wang, Shuxia (2012). Overexpression of cGMP-dependent protein kinase I (PKG-I) attenuates ischemia-reperfusion-induced kidney injury. American Journal of Physiology-Renal Physiology, 302 (5), F561-F570. doi: 10.1152/ajprenal.00355.2011

Overexpression of cGMP-dependent protein kinase I (PKG-I) attenuates ischemia-reperfusion-induced kidney injury

2012

Journal Article

2-arylbenzofuran, flavonoid, and tyrosinase inhibitory constituents of Morus yunnanensis

Hu, Xiao, Wu, Jin-Wei, Wang, Meng, Yu, Mei-Hua, Zhao, Qin-Shi, Wang, He-Yao and Hou, Ai-Jun (2012). 2-arylbenzofuran, flavonoid, and tyrosinase inhibitory constituents of Morus yunnanensis. Journal of Natural Products, 75 (1), 82-87. doi: 10.1021/np2007318

2-arylbenzofuran, flavonoid, and tyrosinase inhibitory constituents of Morus yunnanensis

2012

Conference Publication

Synthesis of nonspherical mesoporous silica ellipsoids with tunable aspect ratios for magnetic assisted assembly and gene delivery

Shen, Shaodian, Gu, Tao, Mao, Dongsen, Xiao, Xiuzhen, Yuan, Pei, Yu, Meihua, Xia, Liyang, Ji, Qiong, Meng, Liang, Song, Wei, Yu, Chengzhong and Lu, Guanzhong (2012). Synthesis of nonspherical mesoporous silica ellipsoids with tunable aspect ratios for magnetic assisted assembly and gene delivery. Washington, DC, United States: American Chemical Society. doi: 10.1021/cm203434k

Synthesis of nonspherical mesoporous silica ellipsoids with tunable aspect ratios for magnetic assisted assembly and gene delivery

2011

Journal Article

Thrombospondin1 Deficiency Reduces Obesity-Associated Inflammation and Improves Insulin Sensitivity in a Diet-Induced Obese Mouse Model

Li, Yanzhang, Tong, Xiaopeng, Rumala, Courtney, Clemons, Kate and Wang, Shuxia (2011). Thrombospondin1 Deficiency Reduces Obesity-Associated Inflammation and Improves Insulin Sensitivity in a Diet-Induced Obese Mouse Model. Plos One, 6 (10) e26656. doi: 10.1371/journal.pone.0026656

Thrombospondin1 Deficiency Reduces Obesity-Associated Inflammation and Improves Insulin Sensitivity in a Diet-Induced Obese Mouse Model

Funding

Past funding

  • 2018 - 2022
    A Nano-platform for Affordable and Ultra-sensitive Bio-marker Detection
    ARC Linkage Projects
    Open grant
  • 2018
    Assessment of Novel Nanoadjuvants for the Development of Potent Therapeutic Cancer Vaccines
    UQ Foundation
    Open grant
  • 2018
    Nanotechnology-medicated therapeutic HPV DNA vaccines
    UQ Early Career Researcher
    Open grant
  • 2017 - 2020
    Engineered Spiky Silica Nanoparticles as Effective Immune Adjuvants by Activating Inflammasome and Enhancing Cellular Uptake
    NHMRC Early Career Fellowships
    Open grant
  • 2016
    Advance Queensland Research Fellowship (Early): Nano-pollen encapsulated lysozyme: a safe alternative to antibiotics for livestock
    Advance Queensland Research Fellowships
    Open grant
  • 2012 - 2013
    A general platform technology for functional nanocomposites with advanced applications
    UWA-UQ Bilateral Research Collaboration Award
    Open grant

Supervision

Availability

Dr Meihua Yu is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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communications@uq.edu.au