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Dr

Timothy McCubbin

Email: 
Phone: 
+61 7 334 63186

Overview

Availability

Dr Timothy McCubbin is:
Available for supervision

Qualifications

  • Bachelor, The University of Queensland
  • Bachelor (Honours), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Timothy McCubbin’s works on UQ eSpace

23 works between 2017 and 2025

1 - 20 of 23 works

2025

Conference Publication

CO(2)-Metabolism: Quantifying Mixed Carbon Oxide And Hydrogen Gas Fermentation By Clostridium Autoethanogenum.

Heffernan, James K., Gonzalez Garcia, R. Axayactl, McCubbin, Timothy, Kopke, Michael, Valgepea, Kaspar, Nielsen, Lars and Marcellin, Esteban (2025). CO(2)-Metabolism: Quantifying Mixed Carbon Oxide And Hydrogen Gas Fermentation By Clostridium Autoethanogenum.. The Carbon Recycling Network Conference 5, Cheshire, United Kingdom, 9-12 March 2025.

CO(2)-Metabolism: Quantifying Mixed Carbon Oxide And Hydrogen Gas Fermentation By Clostridium Autoethanogenum.

2024

Journal Article

Proteomic analysis of natural photoheterotrophic mixed consortium for biohydrogen production under nongrowing conditions

Eduardo Hernández-Guisao, Rafael, Axayacatl González-García, Ricardo, McCubbin, Tim, Guerra-Blanco, Pamela, Salgado Manjarrez, Edgar, Aranda-Barradas, Juan, Velasco, Antonio and Inés García-Peña, Elvia (2024). Proteomic analysis of natural photoheterotrophic mixed consortium for biohydrogen production under nongrowing conditions. Bioresource Technology, 419 132023, 132023. doi: 10.1016/j.biortech.2024.132023

Proteomic analysis of natural photoheterotrophic mixed consortium for biohydrogen production under nongrowing conditions

2024

Journal Article

LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae

Lu, Zeyu, Shen, Qianyi, Bandari, Naga Chandra, Evans, Samuel, Mcdonnell, Liam, Liu, Lian, Jin, Wanli, Luna-Flores, Carlos Horacio, Collier, Thomas, Talbo, Gert, Mccubbin, Tim, Esquirol, Lygie, Myers, Chris, Trau, Matt, Dumsday, Geoff, Speight, Robert, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2024). LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae. Nucleic Acids Research, 52 (12) gkae460, 7367-7383. doi: 10.1093/nar/gkae460

LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae

2024

Journal Article

Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations

Heffernan, James, Garcia Gonzalez, R. Axayactl, Mahamkali, Vishnu, McCubbin, Tim, Daygon, Dara, Liu, Lian, Palfreyman, Robin, Harris, Audrey, Koepke, Michael, Valgepea, Kaspar, Nielsen, Lars Keld and Marcellin, Esteban (2024). Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations. Microbial Biotechnology, 17 (4) e14452, e14452. doi: 10.1111/1751-7915.14452

Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations

2024

Journal Article

A universal molecular control for DNA, mRNA and protein expression

Gunter, Helen M., Youlten, Scott E., Reis, Andre L. M., McCubbin, Tim, Madala, Bindu Swapna, Wong, Ted, Stevanovski, Igor, Cipponi, Arcadi, Deveson, Ira W., Santini, Nadia S., Kummerfeld, Sarah, Croucher, Peter I., Marcellin, Esteban and Mercer, Tim R. (2024). A universal molecular control for DNA, mRNA and protein expression. Nature Communications, 15 (1) 2480, 1-13. doi: 10.1038/s41467-024-46456-9

A universal molecular control for DNA, mRNA and protein expression

2024

Conference Publication

CO(2)-metabolism: quantifying mixed carbon oxide and hydrogen gas fermentation by Clostridium autoethanogenum

Heffernan, James K., Gonzalez-Garcia, R. Axayactl, McCubbin, Timothy, Köpke, Michael, Valgepea, Kaspar, Nielsen, Lars K. and Marcellin, Esteban (2024). CO(2)-metabolism: quantifying mixed carbon oxide and hydrogen gas fermentation by Clostridium autoethanogenum. Gas fermentation conference 2024, Gladstone, QLD Australia, 21-25 February 2024.

CO(2)-metabolism: quantifying mixed carbon oxide and hydrogen gas fermentation by Clostridium autoethanogenum

2024

Journal Article

Amino acid degradation pathway inhibitory by‐products trigger apoptosis in CHO cells

Martínez, Verónica S., Rodriguez, Karen, McCubbin, Timothy, Tong, Junjie, Mahler, Stephen, Shave, Evan, Baker, Kym, Munro, Trent P. and Marcellin, Esteban (2024). Amino acid degradation pathway inhibitory by‐products trigger apoptosis in CHO cells. Biotechnology Journal, 19 (2) e2300338, e2300338. doi: 10.1002/biot.202300338

Amino acid degradation pathway inhibitory by‐products trigger apoptosis in CHO cells

2023

Journal Article

Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network

Lee, Richard G., Rudler, Danielle L., Raven, Samuel A., Peng, Liuyu, Chopin, Anaëlle, Moh, Edward S. X., McCubbin, Tim, Siira, Stefan J., Fagan, Samuel V., DeBono, Nicholas J., Stentenbach, Maike, Browne, Jasmin, Rackham, Filip F., Li, Ji, Simpson, Kaylene J., Marcellin, Esteban, Packer, Nicolle H., Reid, Gavin E., Padman, Benjamin S., Rackham, Oliver and Filipovska, Aleksandra (2023). Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network. Nature Cell Biology, 26 (1), 57-71. doi: 10.1038/s41556-023-01297-4

Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network

2023

Journal Article

Comparative constraint‐based modelling of fruit development across species highlights nitrogen metabolism in the growth‐defence trade‐off

Colombié, Sophie, Prigent, Sylvain, Cassan, Cédric, Hilbert‐Masson, Ghislaine, Renaud, Christel, Dell'Aversana, Emilia, Carillo, Petronia, Moing, Annick, Beaumont, Chloé, Beauvoit, Bertrand, McCubbin, Tim, Nielsen, Lars Keld and Gibon, Yves (2023). Comparative constraint‐based modelling of fruit development across species highlights nitrogen metabolism in the growth‐defence trade‐off. The Plant Journal, 116 (3), 786-803. doi: 10.1111/tpj.16409

Comparative constraint‐based modelling of fruit development across species highlights nitrogen metabolism in the growth‐defence trade‐off

2023

Journal Article

An integrated systems biology approach reveals differences in formate metabolism in the genus Methanothermobacter

Casini, Isabella, McCubbin, Tim, Esquivel-Elizondo, Sofia, Luque, Guillermo G., Evseeva, Daria, Fink, Christian, Beblawy, Sebastian, Youngblut, Nicholas D., Aristilde, Ludmilla, Huson, Daniel H., Dräger, Andreas, Ley, Ruth E., Marcellin, Esteban, Angenent, Largus T. and Molitor, Bastian (2023). An integrated systems biology approach reveals differences in formate metabolism in the genus Methanothermobacter. iScience, 26 (10) 108016, 1-26. doi: 10.1016/j.isci.2023.108016

An integrated systems biology approach reveals differences in formate metabolism in the genus Methanothermobacter

2023

Conference Publication

Quantifying Co-Metabolism of CO/CO2 By Clostridium autoethanogenum in Chemostats

Heffernan, James, Gonzalez-Garcia, R. Axayacatl, McCubbin, Timothy, Köpke, Michael, Valgepea, Kaspar, Nielsen, Lars and Marcellin, Esteban (2023). Quantifying Co-Metabolism of CO/CO2 By Clostridium autoethanogenum in Chemostats. Metabolic Engineering 15, Singapore, 11-15 June 2023.

Quantifying Co-Metabolism of CO/CO2 By Clostridium autoethanogenum in Chemostats

2023

Journal Article

Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer

Stentenbach, Maike, Ermer, Judith A, Rudler, Danielle L, Perks, Kara L, Raven, Samuel A, Lee, Richard G, McCubbin, Tim, Marcellin, Esteban, Siira, Stefan J, Rackham, Oliver and Filipovska, Aleksandra (2023). Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer. EMBO Molecular Medicine, 15 (6) e17463, 1-22. doi: 10.15252/emmm.202317463

Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer

2023

Journal Article

Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation

Hughes, Laetitia A., Rudler, Danielle L., Siira, Stefan J., McCubbin, Tim, Raven, Samuel A., Browne, Jasmin M., Ermer, Judith A., Rientjes, Jeanette, Rodger, Jennifer, Marcellin, Esteban, Rackham, Oliver and Filipovska, Aleksandra (2023). Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation. Nature Communications, 14 (1) 2210, 1-19. doi: 10.1038/s41467-023-37843-9

Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation

2023

Journal Article

Dysregulated energy metabolism impairs chondrocyte function in osteoarthritis

Wu, X., Liyanage, C., Plan, M., Stark, T., McCubbin, T., Barrero, R. A., Batra, J., Crawford, R., Xiao, Y. and Prasadam, I. (2023). Dysregulated energy metabolism impairs chondrocyte function in osteoarthritis. Osteoarthritis and Cartilage, 31 (5), 613-626. doi: 10.1016/j.joca.2022.11.004

Dysregulated energy metabolism impairs chondrocyte function in osteoarthritis

2022

Journal Article

Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease

Lee, Richard G., Balasubramaniam, Shanti, Stentenbach, Maike, Kralj, Tom, McCubbin, Tim, Padman, Benjamin, Smith, Janine, Riley, Lisa G., Priyadarshi, Archana, Peng, Liuyu, Nuske, Madison R., Webster, Richard, Peacock, Ken, Roberts, Philip, Stark, Zornitza, Lemire, Gabrielle, Ito, Yoko A., Boycott, Kym M., Geraghty, Michael T., Klinken, Jan Bert, Ferdinandusse, Sacha, Zhou, Ying, Walsh, Rebecca, Marcellin, Esteban, Thorburn, David R., Rosciolli, Tony, Fletcher, Janice, Rackham, Oliver, Vaz, Frédéric M. ... Care4Rare Canada Consortium (2022). Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease. Human Molecular Genetics, 31 (21), 3597-3612. doi: 10.1093/hmg/ddac040

Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease

2022

Journal Article

A genome-scale metabolic model of Methanoperedens nitroreducens: assessing bioenergetics and thermodynamic feasibility

He, Bingqing, Cai, Chen, McCubbin, Tim, Muriel, Jorge Carrasco, Sonnenschein, Nikolaus, Hu, Shihu, Yuan, Zhiguo and Marcellin, Esteban (2022). A genome-scale metabolic model of Methanoperedens nitroreducens: assessing bioenergetics and thermodynamic feasibility. Metabolites, 12 (4) 314, 314. doi: 10.3390/metabo12040314

A genome-scale metabolic model of Methanoperedens nitroreducens: assessing bioenergetics and thermodynamic feasibility

2021

Journal Article

multiTFA: a Python package for multi-variate thermodynamics-based flux analysis

Mahamkali, Vishnuvardhan, McCubbin, Tim, Beber, Moritz Emanuel, Noor, Elad, Marcellin, Esteban and Nielsen, Lars Keld (2021). multiTFA: a Python package for multi-variate thermodynamics-based flux analysis. Bioinformatics, 37 (18), 3064-3066. doi: 10.1093/bioinformatics/btab151

multiTFA: a Python package for multi-variate thermodynamics-based flux analysis

2020

Journal Article

A pan-genome guided metabolic network reconstruction of five Propionibacterium species reveals extensive metabolic diversity

McCubbin, Tim, Gonzalez-Garcia, R. Axayacatl, Palfreyman, Robin W., Stowers, Chris, Nielsen, Lars K. and Marcellin, Esteban (2020). A pan-genome guided metabolic network reconstruction of five Propionibacterium species reveals extensive metabolic diversity. Genes, 11 (10) 1115, 1-26. doi: 10.3390/genes11101115

A pan-genome guided metabolic network reconstruction of five Propionibacterium species reveals extensive metabolic diversity

2020

Journal Article

Engineering Escherichia coli for propionic acid production through the Wood‐Werkman cycle

Gonzalez‐Garcia, R. A., McCubbin, T., Turner, M. S., Nielsen, L. K. and Marcellin, E. (2020). Engineering Escherichia coli for propionic acid production through the Wood‐Werkman cycle. Biotechnology and Bioengineering, 117 (1), 167-183. doi: 10.1002/bit.27182

Engineering Escherichia coli for propionic acid production through the Wood‐Werkman cycle

2018

Other Outputs

Exploring the metabolism of propionibacteria using genome-scale modelling

McCubbin, Timothy John (2018). Exploring the metabolism of propionibacteria using genome-scale modelling. PhD Thesis, Aust Institute for Bioengineering & Nanotechnology, The University of Queensland. doi: 10.14264/uql.2018.233

Exploring the metabolism of propionibacteria using genome-scale modelling

Funding

Current funding

  • 2024 - 2027
    Production of rare sugars
    Trailblazer Universities Program
    Open grant
  • 2024 - 2028
    Integrated Design Environment for Advanced Biomanufacturing (IDEA Bio) - Bioplatforms Australia (BPA) NCRIS 2022
    Bioplatforms Australia Ltd
    Open grant
  • 2023 - 2025
    Assessing the potential of engineered microbial communities to reduce nitrous oxide (N2O) emissions from agricultural soils
    Grains Research & Development Corporation
    Open grant

Supervision

Availability

Dr Timothy McCubbin is:
Available for supervision

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Media

Enquiries

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