
Overview
Background
Alternate email address: Daniel.Chambers@health.qld.gov.au
Professor Dan Chambers is a thoracic transplant physician, interstitial lung disease expert, and translational clinician researcher. He is an internationally recognised authority in the fields of lung fibrosis, cell therapy for lung disease and lung transplantation. His research focuses on the mechanisms and treatments for lung fibrosis, silicosis, transplant rejection and post-transplant complications.
Graduating from UQ in 1993 with the William Nathaniel Robertson Medal and a University Medal, Dan’s career has continued to be recognised by being named one of Australia’s top 200 researchers in all fields and the most highly cited in the field of transplantation for the last three years. Dan was the immediate past Director of the International Lung and Heart-Lung Transplant Registry, the first Australian to be appointed to that role. The Registry remains the most important source of evidence to guide the practice of transplantation globally.
Dan is Executive Director of Research at Australia’s’ largest health service, Metro North Hospital and Health, and heads one of the world’s largest clinical trials programs in lung fibrosis. He is Chair of the Pulmonary Fibrosis Australiasian Clinical Trials Network (PACT). His research program, located at UQ Thoracic Research Centre at Prince Charles Hospital, has attracted over $20 million. He has authored over 150 original papers and book chapters. He is a regular reviewer for all the highest ranked journals in respiratory and transplantation medicine and is Deputy Editor of the Journal for Heart and Lung Transplantation, the highest impact journal in the field.
Qualifications
MBBS(Hons1) UQ, 1993
MED University of Birmingham, UK
Availability
- Professor Dan Chambers is:
- Available for supervision
- Media expert
Fields of research
Research interests
-
Lung transplantation
-
Lung fibrosis
-
Stem cells
-
Cellular therapy
Research impacts
Professor Chambers is a recognised thought leader in the fields of lung fibrosis, lung cell therapy and lung transplantation. His contributions to these fields have translated into improvements in the management of a wide range of serious lung diseases including silicosis, lung transplant rejection, lung fibrosis and grown up neonatal lung disease. Dan pioneered the use of whole lung lavage to treat acute silicosis, work that has been featured in international media. He was a key member of the team which pioneered ex-vivo lung perfusion to resuscitate marginal donor organs in Australia in 2011. He has used this technology to improve the safety of early phase human trials, and in so doing conceived and developed guidelines for the use of donated human lungs for research in Australia, a document now endorsed by the Transplantation Society of Australia and New Zealand and utilised around the country.
His contribution to knowledge in these diverse areas has been recognised in his appointment to several governmental panels including the Biologicals Advisory Committee (Therapeutic Goods Administration, 2017-2019), the Interim Advisory Panel of the Notifiable Dust Lung Disease Register (Qld Government, 2020-2021), the Virtual Cross Match Working Group (Organ and Tissue Authority, 2020-2021) and the Registry Build Advisory Group for the National Occupational Lung Disease Registry (Australian Government Department of Health, 2020-). He has either chaired or contributed to committees and working groups which have developed international position statements or guidelines in diverse areas of advanced lung disease including the management of fungal infection, conduct of bronchoalveolar lavage, donor and recipient lung transplant management, and in the diagnosis and management of interstitial lung disease. He runs one of the world's largest clinical trial centres focussed on interstitial lung disease and has collaborated with multiple academic and industry partners to bring new treatments to patients with serious lung disease. His work is regularly featured in the Australian media.
Works
Search Professor Dan Chambers’s works on UQ eSpace
2005
Journal Article
Are blood cultures necessary in community-acquired pneumonia?
Chambers, Daniel C. and Waterer, Grant W. (2005). Are blood cultures necessary in community-acquired pneumonia?. Clinical Pulmonary Medicine, 12 (3), 146-152. doi: 10.1097/01.cpm.0000163189.23997.f0
2003
Journal Article
Exhaled nitric oxide in cystic fibrosis patients with allergic bronchopulmonary aspergillosis
Lim, YH, Chambers, DC, Ayres, JG, Stableforth, DE and Honeybourne, D (2003). Exhaled nitric oxide in cystic fibrosis patients with allergic bronchopulmonary aspergillosis. Respiratory Medicine, 97 (4), 331-336. doi: 10.1053/rmed.2002.1430
2001
Journal Article
Effects of nitrogen dioxide exposure and ascorbic acid supplementation on exhaled nitric oxide in healthy human subjects
Chambers, DC and Ayres, JG (2001). Effects of nitrogen dioxide exposure and ascorbic acid supplementation on exhaled nitric oxide in healthy human subjects. Thorax, 56 (10), 774-778. doi: 10.1136/thorax.56.10.774
2001
Journal Article
Effect of nebulised L- and D-arginine on exhaled nitric oxide in steroid naive asthma
Chambers, DC and Ayres, JG (2001). Effect of nebulised L- and D-arginine on exhaled nitric oxide in steroid naive asthma. Thorax, 56 (8), 602-606. doi: 10.1136/thorax.56.8.602
2001
Journal Article
Exchange dynamics of nitric oxide in the human nose
Chambers, DC, Carpenter, DA and Ayres, JG (2001). Exchange dynamics of nitric oxide in the human nose. Journal of Applied Physiology, 91 (5), 1924-1930.
1999
Journal Article
Chronic respiratory symptoms, von Willebrand factor and longitudinal decline in FEV1
Chambers, DC, Boldy, DAR and Ayres, JG (1999). Chronic respiratory symptoms, von Willebrand factor and longitudinal decline in FEV1. Respiratory Medicine, 93 (10), 726-733. doi: 10.1016/S0954-6111(99)90040-9
1998
Journal Article
Acute inhalation of cigarette smoke increases lower respiratory tract nitric oxide concentrations
Chambers, DC, Tunnicliffe, WS and Ayres, JG (1998). Acute inhalation of cigarette smoke increases lower respiratory tract nitric oxide concentrations. Thorax, 53 (8), 677-679. doi: 10.1136/thx.53.8.677
1998
Journal Article
Plasma levels of von Willebrand factor antigen in acute bronchitis and in a normal population
Boldy, Dar, Short, PE, Cowen, P, Hill, FGH, Chambers, DC and Ayres, JG (1998). Plasma levels of von Willebrand factor antigen in acute bronchitis and in a normal population. Respiratory Medicine, 92 (3), 395-400. doi: 10.1016/S0954-6111(98)90281-5
Funding
Current funding
Supervision
Availability
- Professor Dan Chambers is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
The human pulmonary fibrosis transcriptome at single cell resolution
Principal Advisor
Other advisors: Dr Quan Nguyen
-
Doctor Philosophy
Development of Multimodal Machine Learning Tools for Precision Pulmonary Fibrosis Care
Associate Advisor
Other advisors: Dr Quan Nguyen
-
Doctor Philosophy
What is the relationship between nutritional status of patients pre-lung transplant and their association with post-lung transplant outcomes
Associate Advisor
-
Doctor Philosophy
Immune Regulation of Lung Injury: Pathways to Repair, Restoration and Fibrosis
Associate Advisor
Other advisors: Professor Gabrielle Belz
Completed supervision
-
2021
Doctor Philosophy
Investigations into The Endothelial Glycocalyx in Lung Transplantation: Valuable Biomarker and Therapeutic Target
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
-
2023
Doctor Philosophy
Antibody-Dependent Serum Resistance of Intractable Lung Bacteria
Associate Advisor
Other advisors: Associate Professor Timothy Wells
Media
Enquiries
Contact Professor Dan Chambers directly for media enquiries about:
- Idiopathic pulmonary fibrosis
- Lung fibrosis
- Lung transplantation
- Silicosis
- Stem cell therapy
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: