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2014 Journal Article Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destructionGreenhill, Claire J., Jones, Gareth W., Nowell, Mari A., Newton, Zarabeth, Harvey, Ann K., Moideen, Abdul N., Collins, Fraser L., Bloom, Anja C., Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., Rosas, Marcela, Taylor, Philip R., O'Neill, Luke A., Humphreys, Ian R., Williams, Anwen S. and Jones, Simon A. (2014). Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction. Arthritis Research and Therapy, 16 (4) 419. doi: 10.1186/s13075-014-0419-y |
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2014 Conference Publication Control of the human Th1 response via autocrine complement-regulated NLRP3 inflammasome activation within CD4(+) T cellsArbore, Giuseppina, Fara, Antonella F., Coll, Rebecca, Robertson, Avril, Cooper, Matthew, O'Neill, Luke A. J., Lavender, Paul, Cope, Andrew, Lachmann, Helen J. and Kemper, Claudia (2014). Control of the human Th1 response via autocrine complement-regulated NLRP3 inflammasome activation within CD4(+) T cells. 25th International Complement Workshop, Rio de Janeiro, Brazil, 14-18 September 2014. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2014.07.010 |
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2014 Conference Publication What causes Kupffer cell activation in NAFLD? HMGB1, TLR4, crystals and NLRP3 inflammasome link free cholesterol to inhibitable pro-inflammatory pathways in NASHGan, L. T., Van Rooyen, D. M., Cooper, M., Robertson, A., Masters, S., Teoh, N. and Farrell, G. (2014). What causes Kupffer cell activation in NAFLD? HMGB1, TLR4, crystals and NLRP3 inflammasome link free cholesterol to inhibitable pro-inflammatory pathways in NASH. Australian Gastroenterology Week, Broadbeach, QLD, Australia, 22-24 october 2014. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736 |
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2014 Conference Publication Novel Compound Cytokine Release Inhibitory Drug 3 (CRID3) Inhibits the NLRP3 Inflammasome in Rheumatoid ArthritisMcGarry, Trudy, Connolly, Mary, Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., O'Neill, Luke A., Veale, Douglas J. and Fearon, Ursula (2014). Novel Compound Cytokine Release Inhibitory Drug 3 (CRID3) Inhibits the NLRP3 Inflammasome in Rheumatoid Arthritis. 78th Annual Meeting of the American College of Rheumatology/49th Annual Meeting of the Association of Rheumatology Health Professionals, Boston, MA United States, 14-19 November 2014. Hoboken, NJ United States: John Wiley and Sons. |
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2014 Conference Publication MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseasesColl, Rebecca C., Robertson, Avril A. B., Chae, Jae Jin, Higgins, Sarah C., Dungan, Lara S., Munoz-Planillo, Raul, Monks, Brian G., Croker, Daniel E., Sutton, Caroline E., Stutz, Andrea, Nunez, Gabriel, Latz, Eicke, Kastner, Daniel L., Mills, Kingston H. G., Masters, Seth L., Schroder, Kate, Cooper, Matt A. and O'Neill, Luke A. J. (2014). MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, Oct 26-29, 2014. London United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.037 |
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2014 Conference Publication Combined in Vivo and in Vitro Analyses Identify the Caspase-1/trpm2 Axis as a Contributor to Neutrophil-Driven Airway Inflammation in Cystic FibrosisForrest, O., Ingersoll, S., Robertson, A. A., Preininger, M., Laval, J., Brown, M., O'Neill, L., Cooper, M. A., Tangpricha, V and Tirouvanziam, R. (2014). Combined in Vivo and in Vitro Analyses Identify the Caspase-1/trpm2 Axis as a Contributor to Neutrophil-Driven Airway Inflammation in Cystic Fibrosis. The 28th Annual North American Cystic Fibrosis Conference, Atlanta, GA United States, 9-11 October 2014. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/ppul.23108 |
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2014 Conference Publication Cytokine release inhibitor drug, CRID3, inhibits the NLRP3 inflammasome in gliaDempsey, Colin, Coll, Rebecca, Robertson, Avril, Cooper, Matthew, O'Neill, Luke and Lynch, Marina (2014). Cytokine release inhibitor drug, CRID3, inhibits the NLRP3 inflammasome in glia. 12th International Congress of Neuroimmunology (ISNI), Mainz Germany, 9-13 November 2014. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/j.jneuroim.2014.08.393 |
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2013 Journal Article Erratum: The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomesColl, R. C., Robertson, A. A.B., Butler, M., Cooper, M. and O'Neill, L. A.J. (2013). Erratum: The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes. PLoS ONE, 8 (7) e29539. doi: 10.1371/annotation/78d328b9-2c8c-4978-84b1-7e6a0b12ada1 |
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2013 Journal Article Efficient synthesis of anacardic acid analogues and their antibacterial activitiesMamidyala, Sreeman K., Ramu, Soumya, Huang, Johnny X., Robertson, Avril A. B. and Cooper, Matthew A. (2013). Efficient synthesis of anacardic acid analogues and their antibacterial activities. Bioorganic & Medicinal Chemistry Letters, 23 (6), 1667-1670. doi: 10.1016/j.bmcl.2013.01.074 |
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2012 Journal Article Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cellsLin, Y., Richards, F. M., Krippendorff, B - F., Bramhall, J. L., Harrington, J. A., Bapiro, T. E., Robertson, A., Zheleva, D. and Jodrell, D. I. (2012). Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells. BJC, 107 (10), 1692-1701. doi: 10.1038/bjc.2012.450 |
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2011 Journal Article The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomesColl, Rebecca C., Robertson, Avril, Butler, Mark, Cooper, Matthew and O'Neill, Luke A. J. (2011). The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes. PLoS ONE, 6 (12) e29539, e29539. doi: 10.1371/journal.pone.0029539 |
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2007 Conference Publication The synthesis of isotopically labelled glucosinolates for analysis and metabolic studiesBotting, Nigel P., Robertson, Avril A. B. and Morrison, John J. (2007). The synthesis of isotopically labelled glucosinolates for analysis and metabolic studies. Ninth International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds, Edinburgh, Scotland, United Kingdom, 16–20 July 2006. Bognor Regis, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/jlcr.1225 |
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2006 Journal Article The synthesis of glucosinolates deuterium labelled in the glucose fragmentRobertson, Avril and Botting, Nigel P. (2006). The synthesis of glucosinolates deuterium labelled in the glucose fragment. Journal of Labelled Compounds and Radiopharmaceuticals, 49 (13), 1201-1211. doi: 10.1002/jlcr.1141 |
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2005 Other Outputs Preparation of aroyl-O-piperidine derivatives as microsomal triglyceride transfer protein (MTP) and/or apoprotein B (ApoB) inhibitors useful in the treatment of dyslipidemia and related diseasesDumas, Herve, Barbanton, Jacques, Collonges, Francois, Decerprit, Jacques, Ortholand, Jean-Yves, Benzies, David, Cameron, Stuart, Foster, Richard, Guessregen, Stefan, Kane, Peter, Lainton, Julia, Robertson, Avril, Wendt, Bernd and Warne, Mark (2005). Preparation of aroyl-O-piperidine derivatives as microsomal triglyceride transfer protein (MTP) and/or apoprotein B (ApoB) inhibitors useful in the treatment of dyslipidemia and related diseases. WO2005121091. |
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2004 Other Outputs N-Benzodioxolyl, N-benzodioxanyl and N -benzodioxepinyl arylcarboxamide derivatives and pharmaceutical compositions comprising themDumas, Herve, Barbanton, Jacques, Collonges, Francois, Decerprit, Jacques, Ortholand, Jean-Yves, Benzies, David, Cameron, Stuart, Foster, Richard, Guessregen, Stefan, Kane, Peter, Lainton, Julia, Robertson, Avril, Wendt, Bernd and Warne, v (2004). N-Benzodioxolyl, N-benzodioxanyl and N -benzodioxepinyl arylcarboxamide derivatives and pharmaceutical compositions comprising them. WO2004037806. |
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2003 Journal Article The Bohlmann–Rahtz route to functionalised pyridine scaffolds and their use in library synthesisBashford, Katherine E., Burton, Matthew B., Cameron, Stuart, Cooper, Anthony L., Hogg, Rebecca D., Kane, Peter D., MacManus, David A., Matrunola, Christopher A., Moody, Christopher J., Robertson, Avril A. B. and Warne, Mark R. (2003). The Bohlmann–Rahtz route to functionalised pyridine scaffolds and their use in library synthesis. Tetrahedron Letters, 44 (8), 1627-1629. doi: 10.1016/S0040-4039(03)00034-0 |
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2001 Journal Article High-performance liquid chromatographic separation of natural and synthetic desulphoglucosinolates and their chemical validation by UV, NMR and chemical ionisation-MS methodsKiddle, Guy, Bennett, Richard N., Botting, Nigel P., Davidson, Nicola E., Robertson, Avril A. B. and Wallsgrove, Roger M. (2001). High-performance liquid chromatographic separation of natural and synthetic desulphoglucosinolates and their chemical validation by UV, NMR and chemical ionisation-MS methods. Phytochemical Analysis, 12 (4), 226-242. doi: 10.1002/pca.589 |
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2000 Journal Article Evaluation of liquid chromatography–atmospheric pressure chemical ionisation–mass spectrometry for the identification and quantification of desulphoglucosinolatesGriffiths, D. W., Bain, H., Deighton, N., Botting, N. P. and Avril Robertson (2000). Evaluation of liquid chromatography–atmospheric pressure chemical ionisation–mass spectrometry for the identification and quantification of desulphoglucosinolates. Phytochemical Analysis, 11 (4), 216-225. doi: 10.1002/1099-1565(200007/08)11:43.3.CO;2-U |
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1999 Journal Article Synthesis of deuterium labelled desulfoglucosinolates as internal standards for LC-MS analysisRobertson, Avril and Botting, Nigel P. (1999). Synthesis of deuterium labelled desulfoglucosinolates as internal standards for LC-MS analysis. Tetrahedron, 55 (46), 13269-13284. doi: 10.1016/S0040-4020(99)00817-0 |
