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2016 Journal Article Natural structural diversity within a conserved cyclic peptide scaffoldElliott, Alysha G., Franke, Bastian, Armstrong, David A., Craik, David J., Mylne, Joshua S. and Rosengren, K. Johan (2016). Natural structural diversity within a conserved cyclic peptide scaffold. Amino Acids, 49 (1), 1-14. doi: 10.1007/s00726-016-2333-x |
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2015 Journal Article Effects of Cyclization on Peptide Backbone DynamicsWang, Conan K., Swedberg, Joakim E., Northfield, Susan E. and Craik, David J. (2015). Effects of Cyclization on Peptide Backbone Dynamics. Journal of Physical Chemistry B, 119 (52), 15821-15830. doi: 10.1021/acs.jpcb.5b11085 |
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2015 Journal Article Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migrationChan, Lai Yue, Craik, David J. and Daly, Norelle L. (2015). Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration. Bioscience Reports, 35 (6) e00270, e00270-e00270. doi: 10.1042/BSR20150210 |
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2015 Journal Article Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxinsAkcan, Muharrem, Clark, Richard J., Daly, Norelle L., Conibear, Anne C., de Faoite, Andrew, Heghinian, Mari D., Sahil, Talwar, Adams, David J., Mari, Frank and Craik, David J. (2015). Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins. Peptide Science, 104 (6), 682-692. doi: 10.1002/bip.22699 |
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2015 Journal Article PrefaceCraik, David J. (2015). Preface. Plant Cyclotides, 76, XI-XIII. doi: 10.1016/S0065-2296(15)00118-4 |
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2015 Journal Article Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceaeRavipati, Anjaneya S., Henriques, Sónia Troeira, Poth, Aaron G., Kaas, Quentin, Wang, Conan K., Colgrave, Michelle L. and Craik, David J. (2015). Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae. ACS Chemical Biology, 10 (11), 2491-2500. doi: 10.1021/acschembio.5b00454 |
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2015 Journal Article Distribution of circular proteins in plants: large-scale mapping of cyclotides in the ViolaceaeBurman, Robert, Yeshak, Mariamawit Y., Larsson, Sonny, Craik, David J., Rosengren, K. Johan and Goeransson, Ulf (2015). Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae. Frontiers in Plant Science, 6 (855) 855, 1-13. doi: 10.3389/fpls.2015.00855 |
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2015 Journal Article Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonistsSwedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Durek, Thomas, Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Liras, Spiros, Price, David A. and Craik, David J. (2015). Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists. European Journal of Medicinal Chemistry, 103, 175-184. doi: 10.1016/j.ejmech.2015.08.046 |
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2015 Journal Article Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide libraryde Veer, Simon J., Wang, Conan, Harris, Jonathan M., Craik, David J. and Swedberg, Joakim E. (2015). Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library. Journal of Medicinal Chemistry, 58 (20), 8257-8268. doi: 10.1021/acs.jmedchem.5b01148 |
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2015 Journal Article Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1Yu, Rilei, Seymour, Victoria A. L., Berecki, Geza, Jia, Xinying, Akcan, Muharrem, Adams, David J., Kaas, Quentin and Craik, David J. (2015). Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Scientific Reports, 5 (Art No.: 13264) 13264, 13264. doi: 10.1038/srep13264 |
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2015 Journal Article The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering CellsHenriques, Sonia Troeira, Huang, Yen-Hua, Chaousis, Stephanie, Sani, Marc-Antoine, Poth, Aaron G., Separovic, Frances and Craik, David J. (2015). The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells. Chemistry and Biology, 22 (8) 3107, 1087-1097. doi: 10.1016/j.chembiol.2015.07.012 |
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2015 Journal Article Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffoldHuang, Yen-Hua, Henriques, Sonia T., Wang, Conan K., Thorstholm, Louise, Daly, Norelle L., Kaas, Quentin and Craik, David J. (2015). Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Scientific Reports, 5 (1) 12974, 1-15. doi: 10.1038/srep12974 |
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2015 Journal Article Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faeciumHimeno, Kohei, Rosengren, K. Johan, Inoue, Tomoko, Perez, Rodney H., Colgrave, Michelle L., Lee, Han Siean, Chan, Lai Y., Henriques, Sonia Troeira, Fujita, Koji, Ishibashi, Naoki, Zendo, Takeshi, Wilaipun, Pongtep, Nakayama, Jiro, Leelawatcharamas, Vichien, Jikuya, Hiroyuki, Craik, David J. and Sonomoto, Kenji (2015). Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium. Biochemistry, 54 (31), 4863-4876. doi: 10.1021/acs.biochem.5b00196 |
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2015 Journal Article Synergistic activity of the plant defensin HsAFP1 and caspofungin against Candida albicans biofilms and planktonic culturesVriens, Kim, Cools, Tanne L., Harvey, Peta J., Craik, David J., Spincemaille, Pieter, Cassiman, David, Braem, Annabel, Vleugels, Jozef, Nibbering, Peter H., Drijfhout, Jan Wouter, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2015). Synergistic activity of the plant defensin HsAFP1 and caspofungin against Candida albicans biofilms and planktonic cultures. PLoS ONE, 10 (8) e0132701, 1-22. doi: 10.1371/journal.pone.0132701 |
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2015 Journal Article Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonistLuo, Sulan, Zhangsun, Dongting, Harvey, Peta J., Kaas, Quentin, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Li, Xiaodan, Tsetlin, Victor. I., Christensen, Sean, Romero, Haylie K., McIntrye, Melissa, Dowell, Cheryl, Baxter, James, C., Elmslie, Keith S., Craik, David J. and McIntosh, Michael (2015). Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 112 (30), e4026-e4035. doi: 10.1073/pnas.1503617112 |
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2015 Journal Article Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibitionde Veer, Simon J., Swedberg, Joakim E., Akcan, Muharrem, Rosengren, K. Johan, Brattsand, Maria, Craik, David J. and Harris, Jonathan M. (2015). Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition. Biochemical Journal, 469 (2), 243-253. doi: 10.1042/BJ20150412 |
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2015 Journal Article Key challenges for the creation and maintenance of specialist protein resourcesHolliday, Gemma L., Bairoch, Amos, Bagos, Pantelis G., Chatonnet, Arnaud, Craik, David J., Flinn, Robert D., Henrissat, Bernard, Landsman, David, Manning, Gerard, Nagano, Nozomi, O'Donovan, Claire, Pruitt, Kim D., Rawlings, Neil D., Saier, Milton, Sowdhamini, Ramanathan, Spedding, Michael, Srinivasan, Narayanaswamy, Vriend, Gert, Babbitt, Patricia C. and Bateman, Alex (2015). Key challenges for the creation and maintenance of specialist protein resources. Proteins: Structure, Function and Bioinformatics, 83 (6), 1005-1013. doi: 10.1002/prot.24803 |
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2015 Journal Article Bioinformatics-aided venomicsKaas, Quentin and Craik, David J. (2015). Bioinformatics-aided venomics. Toxins, 7 (6), 2159-2187. doi: 10.3390/toxins7062159 |
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2015 Journal Article Peptide macrocyclization by a bifunctional endoproteaseBernath-Levin, Kalia, Nelson, Clark, Elliott, Alysha G., Jayasena, Achala S., Millar, A. Harvey, Craik, David J. and Mylne, Joshua S. (2015). Peptide macrocyclization by a bifunctional endoprotease. Chemistry and Biology, 22 (5), 571-582. doi: 10.1016/j.chembiol.2015.04.010 |
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2015 Journal Article Exploring experimental and computational markers of cyclic peptides: charting islands of permeabilityWang, Conan K., Northfield, Susan Ellen, Swedberg, Joakim E., Colless, Barbara, Chaousis, Stephanie, Price, David A., Liras, Spiros and Craik, David J. (2015). Exploring experimental and computational markers of cyclic peptides: charting islands of permeability. European Journal of Medicinal Chemistry, 97, 202-213. doi: 10.1016/j.ejmech.2015.04.049 |
