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2016

Journal Article

The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms

Vriens, Kim, Cools, Tanne L., Harvey, Peta J., Craik, David J., Braem, Annabel, Vleugels, Jozef, Coninck, Barbara De, Cammue, Bruno P. A. and Thevissen, Karin (2016). The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms. Peptides, 75, 71-79. doi: 10.1016/j.peptides.2015.11.001

The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms

2016

Conference Publication

Modulation of colonic sensory signaling by novel alpha-conotoxin Vc1.1 analogues in mice

Deiteren, A., Castro, J., O'Donnell, T., Craik, D. J., Adams, D. J. and Brierley, S. M. (2016). Modulation of colonic sensory signaling by novel alpha-conotoxin Vc1.1 analogues in mice. 2nd Federation of Neurogastroenterology and Motility Meeting, San Francisco, California, United States, 25-28 August, 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/nmo.12881

Modulation of colonic sensory signaling by novel alpha-conotoxin Vc1.1 analogues in mice

2016

Conference Publication

Towards An Understanding of A- Conotoxin Receptor Specificity

Kaas, Q. and Craik, D. J. (2016). Towards An Understanding of A- Conotoxin Receptor Specificity. HOBOKEN: Wiley.

Towards An Understanding of A- Conotoxin Receptor Specificity

2016

Conference Publication

Structure-Activity Relationship Studies Reveal that the Spider Toxin Protx-II has Unusual Membrane-Binding Properties and Inhibits NAV1.7 Channel at the Membrane Surface

Henriques, Sonia Troeira, Craik, David J. and Schroeder, Christina I. (2016). Structure-Activity Relationship Studies Reveal that the Spider Toxin Protx-II has Unusual Membrane-Binding Properties and Inhibits NAV1.7 Channel at the Membrane Surface. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, United States, Feb 27-Mar 02, 2016. CAMBRIDGE: CELL PRESS.

Structure-Activity Relationship Studies Reveal that the Spider Toxin Protx-II has Unusual Membrane-Binding Properties and Inhibits NAV1.7 Channel at the Membrane Surface

2016

Journal Article

Natural structural diversity within a conserved cyclic peptide scaffold

Elliott, Alysha G., Franke, Bastian, Armstrong, David A., Craik, David J., Mylne, Joshua S. and Rosengren, K. Johan (2016). Natural structural diversity within a conserved cyclic peptide scaffold. Amino Acids, 49 (1), 1-14. doi: 10.1007/s00726-016-2333-x

Natural structural diversity within a conserved cyclic peptide scaffold

2016

Conference Publication

Design and plant-based production of therapeutic cyclic peptides

Craik, D., Oguis, G. K., Smithies, B., Qu, H., Gilding, E. K. and Jackson, M. A. (2016). Design and plant-based production of therapeutic cyclic peptides. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Oxford, United Kingdom: John Wiley & Sons.

Design and plant-based production of therapeutic cyclic peptides

2016

Conference Publication

Probing voltage-dependent structural changes of the VSD in mammalian Nav with LRET

Kubota, Tomoya, Durek, Thomas, Finol-Urdaneta, Rocio K., Craik, David J., French, Robert J., Bezanilla, Francisco and Correa, Ana M. (2016). Probing voltage-dependent structural changes of the VSD in mammalian Nav with LRET. 60th Annual Meeting of the Biophysical Society, Los Angeles, United States, Feb 27-Mar 02, 2016. St. Louis, United States: Cell Press. doi: 10.1016/j.bpj.2015.11.665

Probing voltage-dependent structural changes of the VSD in mammalian Nav with LRET

2016

Conference Publication

Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating

Deplazes, Evelyne, Henriques, Sonia Troeira, King, Glenn F., Craik, David J., Mark, Alan E. and Schroeder, Christina I. (2016). Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating. 60th Annual Meeting of the Biophysical-Society, Los Angeles, United States, February 27- March 2 2016. St Louis, United States: Cell Press. doi: 10.1016/j.bpj.2015.11.220

Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating

2016

Conference Publication

Inhibitory Effects of Substrate-Based Bcr-Abl1 Kinase Inhibitors On the Growth of Chronic Myeloid Leukemia Cell Line K562

Huang, Y. -H., Henriques, S. Troeira, Lawrence, N., Kaas, Q. and Craik, D. J. (2016). Inhibitory Effects of Substrate-Based Bcr-Abl1 Kinase Inhibitors On the Growth of Chronic Myeloid Leukemia Cell Line K562. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2950

Inhibitory Effects of Substrate-Based Bcr-Abl1 Kinase Inhibitors On the Growth of Chronic Myeloid Leukemia Cell Line K562

2015

Journal Article

Effects of Cyclization on Peptide Backbone Dynamics

Wang, Conan K., Swedberg, Joakim E., Northfield, Susan E. and Craik, David J. (2015). Effects of Cyclization on Peptide Backbone Dynamics. Journal of Physical Chemistry B, 119 (52), 15821-15830. doi: 10.1021/acs.jpcb.5b11085

Effects of Cyclization on Peptide Backbone Dynamics

2015

Journal Article

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration

Chan, Lai Yue, Craik, David J. and Daly, Norelle L. (2015). Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration. Bioscience Reports, 35 (6) e00270, e00270-e00270. doi: 10.1042/BSR20150210

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration

2015

Journal Article

Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins

Akcan, Muharrem, Clark, Richard J., Daly, Norelle L., Conibear, Anne C., de Faoite, Andrew, Heghinian, Mari D., Sahil, Talwar, Adams, David J., Mari, Frank and Craik, David J. (2015). Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins. Peptide Science, 104 (6), 682-692. doi: 10.1002/bip.22699

Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins

2015

Journal Article

Preface

Craik, David J. (2015). Preface. Plant Cyclotides, 76, XI-XIII. doi: 10.1016/S0065-2296(15)00118-4

Preface

2015

Journal Article

Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae

Ravipati, Anjaneya S., Henriques, Sónia Troeira, Poth, Aaron G., Kaas, Quentin, Wang, Conan K., Colgrave, Michelle L. and Craik, David J. (2015). Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae. ACS Chemical Biology, 10 (11), 2491-2500. doi: 10.1021/acschembio.5b00454

Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae

2015

Conference Publication

Plants as production vehicles for cyclic therapeutic peptides

Jackson, M.A., Gilding, E.K., Jia, H. and Craik, D.J. (2015). Plants as production vehicles for cyclic therapeutic peptides. 3rd International Conference of Circular Peptides, Moreton Island, QLD, Australia, 1 -4 November 2015.

Plants as production vehicles for cyclic therapeutic peptides

2015

Journal Article

Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae

Burman, Robert, Yeshak, Mariamawit Y., Larsson, Sonny, Craik, David J., Rosengren, K. Johan and Goeransson, Ulf (2015). Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae. Frontiers in Plant Science, 6 (855) 855, 1-13. doi: 10.3389/fpls.2015.00855

Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae

2015

Journal Article

Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists

Swedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Durek, Thomas, Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Liras, Spiros, Price, David A. and Craik, David J. (2015). Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists. European Journal of Medicinal Chemistry, 103, 175-184. doi: 10.1016/j.ejmech.2015.08.046

Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists

2015

Conference Publication

Plants as production vehicles for cyclic therapeutic peptides

Jackson, M.A., Gilding, E.K., Jia, H. and Craik, D.J. (2015). Plants as production vehicles for cyclic therapeutic peptides. Combio, Melbourne, VIC, Australia, 27 September - 1 October 2015.

Plants as production vehicles for cyclic therapeutic peptides

2015

Journal Article

Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library

de Veer, Simon J., Wang, Conan, Harris, Jonathan M., Craik, David J. and Swedberg, Joakim E. (2015). Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library. Journal of Medicinal Chemistry, 58 (20), 8257-8268. doi: 10.1021/acs.jmedchem.5b01148

Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library

2015

Journal Article

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1

Yu, Rilei, Seymour, Victoria A. L., Berecki, Geza, Jia, Xinying, Akcan, Muharrem, Adams, David J., Kaas, Quentin and Craik, David J. (2015). Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Scientific Reports, 5 (Art No.: 13264) 13264, 13264. doi: 10.1038/srep13264

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1