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2015 Journal Article Optimization of the cyclotide framework to improve cell penetration propertiesHuang, Yen-Hua, Chaousis, Steph, Cheneval, Olivier, Craik, David J. and Henriques, Sonia Troeira (2015). Optimization of the cyclotide framework to improve cell penetration properties. Frontiers in Pharmacology, 6 (17) 17, 1-7. doi: 10.3389/fphar.2015.00017 |
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2015 Conference Publication Cyclic penta- and hexa leucine peptides without N-methylation are orally absorbedKok, Woan Mei, Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor G., Schroeder, Christina I., Colless, Barbara, Bernhardt, Paul V., Edmonds, David, Griffith, David, Rotter, Charles, Ruggeri, Roger, Price, David, Liras, Spiros, Craik, David and Fairlie, David (2015). Cyclic penta- and hexa leucine peptides without N-methylation are orally absorbed. American Chemical Society Meeting, x, 2015. Washington, DC United States: American Chemical Society. |
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2015 Journal Article Effects of cyclotides against cutaneous infections caused by Staphylococcus aureusFensterseifer, Isabel C. M., Silva, Osmar N., Malik, Uru, Ravipati, Anjaneya S., Novaes, Natasha R. F., Miranda, Paolo R. R., Rodrigues, Elaine A., Moreno, Susana E., Craik, David J. and Franco, Octavio L. (2015). Effects of cyclotides against cutaneous infections caused by Staphylococcus aureus. Peptides, 63 (3), 38-42. doi: 10.1016/j.peptides.2014.10.019 |
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2015 Journal Article Therapeutic conotoxins: a US patent literature surveyDurek, Thomas and Craik, David J. (2015). Therapeutic conotoxins: a US patent literature survey. Expert Opinion in Therapeutic Patents, 25 (10), 1159-1173. doi: 10.1517/13543776.2015.1054095 |
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2015 Conference Publication Cyclotides, stable drug scaffolds that enter cells after binding to PE-phospholipidsHenriques, S. T., Huang, Y. -H., Chaouis, S., Sani, M. -A., Poth, A. G., Separovic, F. and Craik, D. J. (2015). Cyclotides, stable drug scaffolds that enter cells after binding to PE-phospholipids. 10th European Biophysical Societies Association (EBSA) European Biophysics Congress, Dresden, Germany, Jul 18-22, 2015. Heidelberg, Germany: Springer. |
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2015 Journal Article Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreatBabbitt, Patricia C, Bagos, Pantelis G, Bairoch, Amos, Bateman, Alex, Chatonnet, Arnaud, Chen, Mark Jinan, Craik, David J, Finn, Robert D, Gloriam, David, Haft, Daniel H, Henrissat, Bernard, Holliday, Gemma L, Isberg, Vignir, Kaas, Quentin, Landsman, David, Lenfant, Nicolas, Manning, Gerard, Nagano, Nozomi, Srinivasan, Narayanaswamy, O'Donovan, Claire, Pruitt, Kim D, Sowdhamini, Ramanathan, Rawlings, Neil D, Saier Jr., Milton H, Sharman, Joanna L, Spedding, Michael, Tsirigos, Konstantinos D, Vastermark, Ake and Vriend, Gerrit (2015). Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database The Journal of Biological Databases and Curation, 2015 (bav063). doi: 10.1093/database/bav063 |
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2015 Book Chapter Engineering venom peptides to improve their stability and bioavailabilityAkcan, Muharrem and Craik, David J. (2015). Engineering venom peptides to improve their stability and bioavailability. Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics. (pp. 275-289) edited by Glenn F. King. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00275 |
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2015 Book Chapter Natural functions and structure-activity relationships of cyclotidesOguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2015). Natural functions and structure-activity relationships of cyclotides. Advances in Botanical Research. (pp. 187-226) edited by Craik, DJ. Maryland Heights, United States: Academic Press. doi: 10.1016/bs.abr.2015.10.001 |
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2015 Book Chapter Discovery of peptide drugs from natural sourcesHenriques, Sonia Troeira and Craik, David J. (2015). Discovery of peptide drugs from natural sources. Peptide chemistry and drug design. (pp. 203-245) edited by Ben M. Dunn. Hoboken NJ, United States: John Wiley & Sons. doi: 10.1002/9781118995303.ch6 |
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2015 Conference Publication Pharmaceutical applications of cyclotidesCraik, D. J., Wang, C. and Poth, A. (2015). Pharmaceutical applications of cyclotides. American Society of Pharmacognosy Annual Meeting, Copper Mountain, Colorado United States, 25-29 July 2015. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0035-1556162 |
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2015 Conference Publication Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors designSchroeder, Christina, Henriques, Sonia, Mobli, Mehdi, Chaousis, Stephanie, Walsh, Phillip, Thongyoo, Panumart and Craik, David (2015). Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design. 29th Annual Symposium of the Protein Society, Barcelona Spain, Jul 22-25, 2015. Hoboken, United States: Wiley-Blackwell Publishing. doi: 10.1002/pro.2823 |
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2014 Journal Article Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databasesZhang, Jun, Hua, Zhengshuang, Huang, Zebo, Chen, QiZhu, Long, Qingyun, Craik, David J., Baker, Alan J. M., Shu, Wensheng and Liao, Bin (2014). Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases. Planta, 241 (4), 929-940. doi: 10.1007/s00425-014-2229-5 |
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2014 Journal Article Insights into the molecular flexibility of theta-defensins by NMR relaxation analysisConibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A. and Craik, David J. (2014). Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis. Journal of Physical Chemistry B, 118 (49), 14257-14266. doi: 10.1021/jp507754c |
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2014 Journal Article Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclusVink, Simone, Daly, Norelle L., Steen, Natalie, Craik, David J. and Alewood, Paul F. (2014). Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90 (1), 308-317. doi: 10.1016/j.toxicon.2014.08.068 |
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2014 Journal Article Improving on nature: making a cyclic heptapeptide orally bioavailableNielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Hill, Timothy A., Lucke, Andrew J., Craik, David J., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Improving on nature: making a cyclic heptapeptide orally bioavailable. Angewandte Chemie - International Edition, 53 (45), 12059-12063. doi: 10.1002/anie.201405364 |
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2014 Journal Article Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1Taylor, Carol M., Northfield, Susan E., Wang, Conan K. and Craik, David J. (2014). Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1. Tetrahedron, 70 (42), 7669-7674. doi: 10.1016/j.tet.2014.06.058 |
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2014 Journal Article Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbedHill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823 |
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2014 Journal Article The role of disulfide bonds in structure and activity of chlorotoxinOjeda, Paola G., Chan, Lai Y., Poth, Aaron G., Wang, Conan K. and Craik, David J. (2014). The role of disulfide bonds in structure and activity of chlorotoxin. Future Medicinal Chemistry, 6 (15), 1617-1628. doi: 10.4155/FMC.14.93 |
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2014 Journal Article The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cellsSpincemaille, Pieter, Alborzinia, Hamed, Dekervel, Jeroen, Windmolders, Petra, van Pelt, Jos, Cassiman, David, Cheneval, Olivier, Craik, David J., Schur, Julia, Ott, Ingo, Wolfl, Stefan, Cammue, Bruno P. A and Thevissen, Karin (2014). The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells. Molecules, 19 (9), 15088-15102. doi: 10.3390/molecules190915088 |
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2014 Journal Article Translational diffusion of cyclic peptides measured using pulsed-field gradient NMRWang, Conan K., Northfield, Susan E., Swedberg, Joakim E., Harvey, Peta J., Mathiowetz, Alan M., Price, David A, Liras, Spiros and Craik, David J. (2014). Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR. Journal of Physical Chemistry B, 118 (38), 11129-11136. doi: 10.1021/jp506678f |
