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2015 Book Chapter Natural functions and structure-activity relationships of cyclotidesOguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2015). Natural functions and structure-activity relationships of cyclotides. Advances in Botanical Research. (pp. 187-226) edited by Craik, DJ. Maryland Heights, United States: Academic Press. doi: 10.1016/bs.abr.2015.10.001 |
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2015 Book Chapter Discovery of peptide drugs from natural sourcesHenriques, Sonia Troeira and Craik, David J. (2015). Discovery of peptide drugs from natural sources. Peptide chemistry and drug design. (pp. 203-245) edited by Ben M. Dunn. Hoboken NJ, United States: John Wiley & Sons. doi: 10.1002/9781118995303.ch6 |
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2015 Conference Publication Pharmaceutical applications of cyclotidesCraik, D. J., Wang, C. and Poth, A. (2015). Pharmaceutical applications of cyclotides. American Society of Pharmacognosy Annual Meeting, Copper Mountain, Colorado United States, 25-29 July 2015. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0035-1556162 |
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2015 Conference Publication Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors designSchroeder, Christina, Henriques, Sonia, Mobli, Mehdi, Chaousis, Stephanie, Walsh, Phillip, Thongyoo, Panumart and Craik, David (2015). Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design. 29th Annual Symposium of the Protein Society, Barcelona Spain, Jul 22-25, 2015. Hoboken, United States: Wiley-Blackwell Publishing. doi: 10.1002/pro.2823 |
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2014 Journal Article Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databasesZhang, Jun, Hua, Zhengshuang, Huang, Zebo, Chen, QiZhu, Long, Qingyun, Craik, David J., Baker, Alan J. M., Shu, Wensheng and Liao, Bin (2014). Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases. Planta, 241 (4), 929-940. doi: 10.1007/s00425-014-2229-5 |
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2014 Journal Article Insights into the molecular flexibility of theta-defensins by NMR relaxation analysisConibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A. and Craik, David J. (2014). Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis. Journal of Physical Chemistry B, 118 (49), 14257-14266. doi: 10.1021/jp507754c |
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2014 Journal Article Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclusVink, Simone, Daly, Norelle L., Steen, Natalie, Craik, David J. and Alewood, Paul F. (2014). Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90 (1), 308-317. doi: 10.1016/j.toxicon.2014.08.068 |
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Featured 2014 Journal Article Improving on nature: making a cyclic heptapeptide orally bioavailableNielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Hill, Timothy A., Lucke, Andrew J., Craik, David J., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Improving on nature: making a cyclic heptapeptide orally bioavailable. Angewandte Chemie - International Edition, 53 (45), 12059-12063. doi: 10.1002/anie.201405364 |
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2014 Journal Article Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1Taylor, Carol M., Northfield, Susan E., Wang, Conan K. and Craik, David J. (2014). Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1. Tetrahedron, 70 (42), 7669-7674. doi: 10.1016/j.tet.2014.06.058 |
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2014 Journal Article Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbedHill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823 |
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2014 Journal Article The role of disulfide bonds in structure and activity of chlorotoxinOjeda, Paola G., Chan, Lai Y., Poth, Aaron G., Wang, Conan K. and Craik, David J. (2014). The role of disulfide bonds in structure and activity of chlorotoxin. Future Medicinal Chemistry, 6 (15), 1617-1628. doi: 10.4155/FMC.14.93 |
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2014 Journal Article The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cellsSpincemaille, Pieter, Alborzinia, Hamed, Dekervel, Jeroen, Windmolders, Petra, van Pelt, Jos, Cassiman, David, Cheneval, Olivier, Craik, David J., Schur, Julia, Ott, Ingo, Wolfl, Stefan, Cammue, Bruno P. A and Thevissen, Karin (2014). The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells. Molecules, 19 (9), 15088-15102. doi: 10.3390/molecules190915088 |
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2014 Journal Article Translational diffusion of cyclic peptides measured using pulsed-field gradient NMRWang, Conan K., Northfield, Susan E., Swedberg, Joakim E., Harvey, Peta J., Mathiowetz, Alan M., Price, David A, Liras, Spiros and Craik, David J. (2014). Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR. Journal of Physical Chemistry B, 118 (38), 11129-11136. doi: 10.1021/jp506678f |
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2014 Journal Article Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targetingHenriques, Sonia Troeira, Huang, Yen-Hua, Chaousis, Steph, Wang, Conan and Craik, David J. (2014). Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting. Chembiochem, 15 (13), 1956-1965. doi: 10.1002/cbic.201402144 |
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2014 Journal Article Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formationDelattin, Nicolas, De Brucker, Katrijn, Craik, David J., Cheneval, Olivier, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2014). Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation. Antimicrobial Agents and Chemotherapy, 58 (8), 4974-4977. doi: 10.1128/AAC.03336-14 |
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2014 Journal Article Chemie und Biologie von Theta-DefensinenConibear, Anne C. and Craik, David J. (2014). Chemie und Biologie von Theta-Defensinen. Angewandte Chemie, 126 (40), 10786-10798. doi: 10.1002/ange.201402167 |
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2014 Journal Article Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channelsBerecki, G., Daly, N. L., Huang, Y. H., Vink, S., Craik, D. J., Alewood, P. F. and Adams, D. J. (2014). Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channels. British Journal of Pharmacology, 171 (13), 3313-3327. doi: 10.1111/bph.12686 |
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2014 Journal Article Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1D'Souza, Charlotte, Troeira Henriques, Sonia, Wang, Conan K. and Craik, David J. (2014). Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1. European Journal of Medicinal Chemistry, 88, 10-18. doi: 10.1016/j.ejmech.2014.06.047 |
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2014 Journal Article Fmoc-based synthesis of disulfide-rich cyclic peptidesCheneval, Olivier, Schroeder, Christina I., Durek, Thomas, Walsh, Phillip, Huang, Yen-Hua, Liras, Spiros, Price, David A. and Craik, David J. (2014). Fmoc-based synthesis of disulfide-rich cyclic peptides. Journal of Organic Chemistry, 79 (12), 5538-5544. doi: 10.1021/jo500699m |
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2014 Journal Article The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactanproteinPaulsen, B. S., Craik, D. J., Dunstan, D. E., Stone, B. A. and Bacic, A. (2014). The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactanprotein. Carbohydrate Polymers, 106 (1), 460-468. doi: 10.1016/j.carbpol.2014.01.009 |
