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2014

Journal Article

Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting

Henriques, Sonia Troeira, Huang, Yen-Hua, Chaousis, Steph, Wang, Conan and Craik, David J. (2014). Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting. Chembiochem, 15 (13), 1956-1965. doi: 10.1002/cbic.201402144

Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting

2014

Journal Article

Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation

Delattin, Nicolas, De Brucker, Katrijn, Craik, David J., Cheneval, Olivier, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2014). Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation. Antimicrobial Agents and Chemotherapy, 58 (8), 4974-4977. doi: 10.1128/AAC.03336-14

Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation

2014

Journal Article

Chemie und Biologie von Theta-Defensinen

Conibear, Anne C. and Craik, David J. (2014). Chemie und Biologie von Theta-Defensinen. Angewandte Chemie, 126 (40), 10786-10798. doi: 10.1002/ange.201402167

Chemie und Biologie von Theta-Defensinen

2014

Journal Article

Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channels

Berecki, G., Daly, N. L., Huang, Y. H., Vink, S., Craik, D. J., Alewood, P. F. and Adams, D. J. (2014). Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channels. British Journal of Pharmacology, 171 (13), 3313-3327. doi: 10.1111/bph.12686

Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channels

2014

Journal Article

Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1

D'Souza, Charlotte, Troeira Henriques, Sonia, Wang, Conan K. and Craik, David J. (2014). Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1. European Journal of Medicinal Chemistry, 88, 10-18. doi: 10.1016/j.ejmech.2014.06.047

Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1

2014

Journal Article

Fmoc-based synthesis of disulfide-rich cyclic peptides

Cheneval, Olivier, Schroeder, Christina I., Durek, Thomas, Walsh, Phillip, Huang, Yen-Hua, Liras, Spiros, Price, David A. and Craik, David J. (2014). Fmoc-based synthesis of disulfide-rich cyclic peptides. Journal of Organic Chemistry, 79 (12), 5538-5544. doi: 10.1021/jo500699m

Fmoc-based synthesis of disulfide-rich cyclic peptides

2014

Journal Article

The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactanprotein

Paulsen, B. S., Craik, D. J., Dunstan, D. E., Stone, B. A. and Bacic, A. (2014). The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactanprotein. Carbohydrate Polymers, 106 (1), 460-468. doi: 10.1016/j.carbpol.2014.01.009

The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactanprotein

2014

Journal Article

A comparative study of extraction methods reveals preferred solvents for cystine knot peptide isolation from Momordica cochinchinensis seeds

Mahatmanto, Tunjung, Poth, Aaron, Mylne, Joshua S. and Craik, David J. (2014). A comparative study of extraction methods reveals preferred solvents for cystine knot peptide isolation from Momordica cochinchinensis seeds. Fitoterapia, 95, 22-33. doi: 10.1016/j.fitote.2014.02.016

A comparative study of extraction methods reveals preferred solvents for cystine knot peptide isolation from Momordica cochinchinensis seeds

2014

Journal Article

Discovery, synthesis, and structure: activity relationships of conotoxins

Akondi, Kalyana, Muttenthaler, Markus, Dutertre, Sébastien, Kaas, Quentin, Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2014). Discovery, synthesis, and structure: activity relationships of conotoxins. Chemical Reviews, Articles ASAP (11), 1-33. doi: 10.1021/cr400401e

Discovery, synthesis, and structure: activity relationships of conotoxins

2014

Journal Article

Disulfide-rich macrocyclic peptides as templates in drug design

Northfield, Susan E., Wang, Conan K., Schroeder, Christina I., Durek, Thomas, Kan, Meng-Wei, Swedberg, Joakim E. and Craik, David J. (2014). Disulfide-rich macrocyclic peptides as templates in drug design. European Journal of Medicinal Chemistry, 77 (2), 248-257. doi: 10.1016/j.ejmech.2014.03.011

Disulfide-rich macrocyclic peptides as templates in drug design

2014

Journal Article

Evolutionary origins of a bioactive peptide buried within preproalbumin

Elliott, Alysha G., Delay, Christina, Liu, Huanle, Phua, Zaiyang, Rosengren, K. Johan, Benfield, Aurelie H., Panero, Jose L., Colgrave, Michelle L., Jayasena, Achala S., Dunse, Kerry M., Anderson, Marilyn A., Schilling, Edward E., Ortiz-Barrientos, Daniel, Craik, David J. and Mylne, Joshua S. (2014). Evolutionary origins of a bioactive peptide buried within preproalbumin. The Plant Cell, 26 (3), 981-995. doi: 10.1105/tpc.114.123620

Evolutionary origins of a bioactive peptide buried within preproalbumin

2014

Journal Article

The plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability

Delattin, Nicolas, De Brucker, Katrijn, Craik, David J., Cheneval, Olivier, Frohlich, Mirjam, Veber, Matija, Girandon, Lenart, Davis, Tayla, R., Weeks, Anne E., Kumamoto, Carol A., Cos, Paul, Coenye, Tom, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2014). The plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability. Antimicrobial Agents and Chemotherapy, 58 (5), 2647-2656. doi: 10.1128/AAC.01274-13

The plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability

2014

Journal Article

The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions

Lay, Fung T., Poon, Simon, McKenna, James A., Connelly, Angela A., Barbeta, Barbara L., McGinness, Bruce S., Fox, Jennifer L., Daly, Norelle L., Craik, David J., Heath, Robyn L. and Anderson, Marilyn A. (2014). The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions. BMC Plant Biology, 14 (1) 41, 41.1-41.13. doi: 10.1186/1471-2229-14-41

The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions

2014

Journal Article

The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif

Conibear, Anne C., Bochen, Alexander, Rosengren, K. Johan, Stupar, Petar, Wang, Conan, Kessler, Horst and Craik, David J. (2014). The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif. ChemBioChem, 15 (3), 451-459. doi: 10.1002/cbic.201300568

The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif

2014

Journal Article

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2. Angewandte Chemie International Edition, 53 (4), 1017-1020. doi: 10.1002/anie.201308898

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

2014

Journal Article

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie, 126 (4), 1035-1038. doi: 10.1002/ange.201308898

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

2014

Journal Article

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

2014

Journal Article

Semienzymatic cyclization of disulfide-rich peptides using sortase A

Jia, Xinying, Kwon, Soohyun, Wang, Ching-I Anderson, Huang, Yen-Hua, Chan, Lai Y., Tan, Chia Chia, Rosengren, K. Johan, Mulvenna, Jason P., Schroeder, Christina I. and Craik, David J. (2014). Semienzymatic cyclization of disulfide-rich peptides using sortase A. Journal of Biological Chemistry, Papers in Press (10), 1-25. doi: 10.1074/jbc.M113.539262

Semienzymatic cyclization of disulfide-rich peptides using sortase A

2014

Journal Article

A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3 beta2 vs. alpha6/alpha3 beta2 beta3 nicotinic acetylcholine receptors

Luo, Sulan, Zhangsun, Dongting, Schroeder, Christina I., Zhu, Xiaopeng, Hu, Yuanyan, Wu, Yong, Weltzin, Maegan M., Eberhard, Spencer, Kaas, Quentin, Craik, David J., McIntosh, J. Michael and Whiteaker, Paul (2014). A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3 beta2 vs. alpha6/alpha3 beta2 beta3 nicotinic acetylcholine receptors. FASEB Journal, Early Edition (4), 1-12. doi: 10.1096/fj.13-244103

A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3 beta2 vs. alpha6/alpha3 beta2 beta3 nicotinic acetylcholine receptors

2014

Book Chapter

Cyclotide analysis

Northfield, Susan E., Poth, Aaron, D'Souza, Charlotte and Craik, David J. (2014). Cyclotide analysis. Encyclopedia of Analytical Chemistry. (pp. 1-18) edited by Robert A. Meyers. Hoboken, NJ, USA: John Wiley & Sons. doi: 10.1002/9780470027318.a9933

Cyclotide analysis