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2013 Journal Article Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopiaVerhoeven V.J.M., Hysi P.G., Wojciechowski R., Fan Q., Guggenheim J.A., Hohn R., Macgregor S., Hewitt A.W., Nag A., Cheng C.-Y., Yonova-Doing E., Zhou X., Ikram M.K., Buitendijk G.H.S., Mcmahon G., Kemp J.P., Pourcain B.S., Simpson C.L., Makela K.-M., Lehtimaki T., Kahonen M., Paterson A.D., Hosseini S.M., Wong H.S., Xu L., Jonas J.B., Parssinen O., Wedenoja J., Yip S.P. ... Hammond C.J. (2013). Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nature Genetics, 45 (3), 314-318. doi: 10.1038/ng.2554 |
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2013 Journal Article Examination of the relationship between variation at 17q21 and childhood wheeze phenotypesGranell, R., Henderson A. J., Timpson, N., St. Pourcain, B., Kemp, J. P., Ring, S. M., Ho, K., Montgomery, S. B., Dermitzakis, E. T., Evans, D. M. and Sterne, J. A. C. (2013). Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes. Journal of Allergy and Clinical Immunology, 131 (3), 685-694. doi: 10.1016/j.jaci.2012.09.021 |
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2013 Journal Article Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal womenKoller D.L., Zheng H.-F., Karasik D., Yerges-Armstrong L., Liu C.-T., McGuigan F., Kemp J.P., Giroux S., Lai D., Edenberg H.J., Peacock M., Czerwinski S.A., Choh A.C., McMahon G., St Pourcain B., Timpson N.J., Lawlor D.A., Evans D.M., Towne B., Blangero J., Carless M.A., Kammerer C., Goltzman D., Kovacs C.S., Prior J.C., Spector T.D., Rousseau F., Tobias J.H., Akesson K. ... Foroud T. (2013). Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. Journal of Bone and Mineral Research, 28 (3), 547-558. doi: 10.1002/jbmr.1796 |
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2013 Journal Article Coordinated genetic scaling of the human eye: Shared determination of axial eye length and corneal curvatureGuggenheim, J. A., Zhou, X., Evans, D. M., Timpson, N. J., McMahon, G., Kemp, J. P., Pourcain, B. S., Northstone, K., Ring, S. M., Fan, Q., Wong, T. -Y., Cheng, C. Y., Khor, C. C., Aung, T., Saw, S. M. and Williams, C. (2013). Coordinated genetic scaling of the human eye: Shared determination of axial eye length and corneal curvature. Investigative Ophthalmology and Visual Science, 54 (3), 1715-1721. doi: 10.1167/iovs.12-10560 |
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2013 Journal Article Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructurePaternoster, Lavinia, Lorentzon, Mattias, Lehtimaki, Terho, Eriksson, Joel, Kahonen, Mika, Raitakari, Olli, Laaksonen, Marika, Sievanen, Harri, Viikari, Jorma V, Lyytikainen, Leo-Pekka, Mellstrom, Dan, Karlsson, Magnus, Ljunggren, Osten, Grundberg, Elin, Kemp, John P., Sayers, Adrian, Nethander, Maria, Evans, David M., Vandenput, Liesbeth, Tobias, Jon H. and Ohlsson, Claes (2013). Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. PLoS Genetics, 9 (2) e1003247, 1-15. doi: 10.1371/journal.pgen.1003247 |
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2013 Journal Article Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand SkillBrandler, William M., Morris, Andrew P., Evans, David M., Scerri, Thomas S., Kemp, John P., Timpson, Nicholas J., St Pourcain, Beate, Smith, George Davey, Ring, Susan M., Stein, John, Monaco, Anthony P., Talcott, Joel B., Fisher, Simon E., Webber, Caleb and Paracchini, Silvia (2013). Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill. PLoS Genetics, 9 (9) e1003751, e100375.1-e100375.11. doi: 10.1371/journal.pgen.1003751 |
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2013 Journal Article Common variation contributes to the genetic architecture of social communication traitsSt Pourcain, Beate, Whitehouse, Andrew J. O., Ang, Wei Q., Warrington, Nicole M., Glessner, Joseph T., Wang, Kai, Timpson, Nicholas J., Evans, David M., Kemp, John P., Ring,Susan M., McArdle, Wendy L., Golding, Jean, Hakonarson, Hakon, Pennell, Craig E. and Smith, George Davey (2013). Common variation contributes to the genetic architecture of social communication traits. Molecular Autism, 4 (1) 34, 34.1-34.12. doi: 10.1186/2040-2392-4-34 |
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2013 Journal Article Distinct relationships of intramuscular and subcutaneous fat with cortical bone: Findings from a cross-sectional study of young adult males and femalesDeere, K., Sayers, A., Viljakainen, H. T., Lawlor, D. A., Sattar, N., Kemp, J. P., Fraser, W. D. and Tobias, J. H. (2013). Distinct relationships of intramuscular and subcutaneous fat with cortical bone: Findings from a cross-sectional study of young adult males and females. Journal of Clinical Endocrinology and Metabolism, 98 (6), E1041-E1049. doi: 10.1210/jc.2013-1272 |
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2013 Journal Article Mining the Human Phenome Using Allelic Scores That Index Biological IntermediatesEvans, David M., Brion, Marie Jo A., Paternoster, Lavinia, Kemp, John P., McMahon, George, Munafo, Marcus, Whitfield, John B., Medland, Sarah E., Montgomery, Grant W., The GIANT consortium, The CRP consortium, The TAG Consortium, Timpson, Nicholas J., St. Pourcain, Beate, Lawlor, Debbie A., Martin, Nicholas G., Dehghan, Abbas, Hirschhorn, Joel and Davey Smith, George (2013). Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates. PLoS Genetics, 9 (10) e1003919, e1003919.1-e1003919.15. doi: 10.1371/journal.pgen.1003919 |
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2013 Journal Article Genetic influences on trajectories of systolic blood pressure across childhood and adolescenceHowe, Laura D., Parmar, Priyakumari G., Paternoster, Lavinia, Warrington, Nicole M., Kemp, John P., Briollais, Laurent, Newnham, John P., Timpson, Nicholas J., Smith, George D., Ring, Susan M., Evans, David M., Tilling, Kate, Pennell, Craig E., Beilin, Lawrie J., Palmer, Lyle J. and Lawlor, Debbie A. (2013). Genetic influences on trajectories of systolic blood pressure across childhood and adolescence. Circulation: Cardiovascular Genetics, 6 (6), 608-614. doi: 10.1161/CIRCGENETICS.113.000197 |
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2013 Conference Publication Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of beta-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCTKemp, John P., Sayers, Adrian, Evans, David M., Paternoster, Lavinia, Deere, Kevin, Lorentzon, Mattias, Lehtimaki, Terho, Eriksson, Joel, Kahonen, Mika, Raitakari, Olli, Laaksonen, Marika, Sievanen, Harri, Viikari, Jorma, Lyytikainen, Leo-Pekka, Fraser, William D., Vandenput, Liesbeth, Ohlsson, Claes and Tobias, Jonathan H. (2013). Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of beta-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT. Annual Meeting of the American Society for Bone and Mineral Research, Baltimore, MD, United States, 4-7 October 2013. Hoboken, NJ, United States: Wiley-Blackwell. |
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2013 Journal Article A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white EuropeansGuggenheim, Jeremy A., McMahon, George, Kemp, John P., Akhtar, Saeed, St Pourcain, Beate, Northstone, Kate, Ring, Susan M., Evans, David M., Smith, George Davey, Timpson, Nicholas J. and Williams, Cathy (2013). A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white Europeans. Molecular Vision, 19, 243-253. |
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2013 Journal Article Body stature growth trajectories during childhood and the development of myopiaNorthstone, Kate, Guggenheim, Jeremy A., Howe, Laura D., Tilling, Kate, Paternoster, Lavinia, Kemp, John P., McMahon, George and Williams, Cathy (2013). Body stature growth trajectories during childhood and the development of myopia. Ophthalmology, 120 (5), 1064-1073. doi: 10.1016/j.ophtha.2012.11.004 |
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2013 Journal Article Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distancesFatemifar, Ghazaleh, Hoggart, Clive J., Paternoster, Lavinia, Kemp, John P., Prokopenko, Inga, Horikoshi, Momoko, Wright, Victoria J., Tobias, Jon H., Richmond, Stephen, Zhurov, Alexei I., Toma, Arshed M., Pouta, Anneli, Taanila, Anja, Sipila, Kirsi, Lahdesmaki, Raija, Pillas, Demetris, Geller, Frank, Feenstra, Bjarke, Melbye, Mads, Nohr, Ellen A., Ring, Susan M., St Pourcain, Beate, Timpson, Nicholas J., Smith, George D., Jarvelin, Marjo-Riitta and Evans, David M. (2013). Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Human Molecular Genetics, 22 (18) ddt231, 3807-3817. doi: 10.1093/hmg/ddt231 |
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2013 Journal Article New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolismHorikoshi M., Yaghootkar H., Mook-Kanamori D.O., Sovio U., Taal H.R., Hennig B.J., Bradfield J.P., St Pourcain B., Evans D.M., Charoen P., Kaakinen M., Cousminer D.L., Lehtimaki T., Kreiner-Moller E., Warrington N.M., Bustamante M., Feenstra B., Berry D.J., Thiering E., Pfab T., Barton S.J., Shields B.M., Kerkhof M., Van Leeuwen E.M., Fulford A.J., Kutalik Z., Zhao J.H., Den Hoed M., Mahajan A. ... Freathy R.M. (2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics, 45 (1), 76-82. doi: 10.1038/ng.2477 |
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2012 Journal Article Seventy-five genetic loci influencing the human red blood cellvan der Harst, Pim, Zhang, Weihua, Leach, Irene Mateo, Rendon, Augusto, Verweij, Niek, Sehmi, Joban, Paul, Dirk S., Elling, Ulrich, Allayee, Hooman, Li, Xinzhong, Radhakrishnan, Aparna, Tan, Sian-Tsung, Voss, Katrin, Weichenberger, Christian X., Albers, Cornelis A., Al-Hussani, Abtehale, Asselbergs, Folkert W., Ciullo, Marina, Danjou, Fabrice, Dina, Christian, Esko, Tonu, Evans, David M., Franke, Lude, Goegele, Martin, Hartiala, Jaana, Hersch, Micha, Holm, Hilma, Hottenga, Jouke-Jan, Kanoni, Stavroula ... Chambers, John C. (2012). Seventy-five genetic loci influencing the human red blood cell. Nature, 492 (7429), 369-375. doi: 10.1038/nature11677 |
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2012 Journal Article WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture riskZheng, Hou-Feng, Tobias, Jon H., Duncan, Emma, Evans, David M., Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura M., Lehtimaki, Terho, Bergstrom, Ulrica, Kahonen, Mika, Leo, Paul J., Raitakari, Olli, Laaksonen, Marika, Nicholson, Geoffrey C., Viikari, Jorma, Ladouceur, Martin, Lyytikainen, Leo-Pekka, Medina-Gomez, Carolina, Rivadeneira, Fernando, Prince, Richard L., Sievanen, Harri, Leslie, William D., Mellstrom, Dan, Eisman, John A., Moverare-Skrtic, Sofia, Goltzman, David, Hanley, David A., Jones, Graeme, Pourcain, Beate St. ... Lorentzon, Mattias (2012). WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Plos Genetics, 8 (7) e1002745, e1002745.1-e1002745.13. doi: 10.1371/journal.pgen.1002745 |
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2012 Journal Article Common variants at 12q15 and 12q24 are associated with infant head circumferenceTaal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Møller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Mònica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bønnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., Kim, Cecilia E., Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Middeldorp, Christel (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44 (5), 532-538. doi: 10.1038/ng.2238 |
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2012 Journal Article Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fractureEstrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L., Ntzani, Evangelia E., Oei, Ling, Albagha, Omar M. E., Amin, Najaf, Kemp, John P., Koller, Daniel L., Li, Guo, Liu, Ching-Ti, Minster, Ryan L., Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M., Zheng, Hou-Feng, Alonso, Nerea, Eriksson, Joel, Kammerer, Candace M., Kaptoge, Stephen K., Leo, Paul J., Thorleifsson, Gudmar, Wilson, Scott G., Wilson, James F., Aalto, Ville ... Rivadeneira, Fernando (2012). Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics, 44 (5), 491-501. doi: 10.1038/ng.2249 |
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2012 Journal Article A genome-wide association meta-analysis identifies new childhood obesity lociBradfield, Jonathan P., Taal, H. Rob, Timpson, Nicholas J., Scherag, André, Lecoeur, Cecile, Warrington, Nicole M., Hypponen, Elina, Holst, Claus, Valcarcel, Beatriz, Thiering, Elisabeth, Salem, Rany M., Schumacher, Fredrick R., Cousminer, Diana L., Sleiman, Patrick M. A., Zhao, Jianhua, Berkowitz, Robert I., Vimaleswaran, Karani S., Jarick, Ivonne, Pennell, Craig E., Evans, David M., St Pourcain, Beate, Berry, Diane J., Mook-Kanamori, Dennis O., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., van Duijn, Cornelia M., van der Valk, Ralf J. P., de Jongste, Johan C. ... Grant, Struan F. A. (2012). A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics, 44 (5), 526-531. doi: 10.1038/ng.2247 |
