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2026 Journal Article Automated Abdominal Aortic Calcification Scores and Atherosclerotic Cardiovascular Disease in the UK Biobank Imaging StudySim, Marc, Webster, James, Smith, Cassandra, Saleem, Afsah, Gilani, Syed Zulqarnain, Toro-Huamanchumo, Carlos J., Suter, David, Figtree, Gemma, Lagendijk, Anne Karine, Duncan, Emma L., Schultz, Carl, Szulc, Pawel, Hung, Joseph, Lim, Wai H., Raina, Parminder, Bondonno, Nicola P., Woodman, Richard, Hodgson, Jonathan M., Kiel, Douglas P., Prince, Richard L., Leslie, William D., Kemp, John P., Harvey, Nicholas C., Schousboe, John T. and Lewis, Joshua R. (2026). Automated Abdominal Aortic Calcification Scores and Atherosclerotic Cardiovascular Disease in the UK Biobank Imaging Study. JACC: Advances, 5 (3) 102570, 102570. doi: 10.1016/j.jacadv.2025.102570 |
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2025 Conference Publication AUTOMATED ABDOMINAL AORTIC CALCIFICATION EXTENT IS ASSOCIATED WITH MUSCLE COMPOSITION, STRENGTH AND SARCOPENIA: THE UK BIOBANK IMAGING STUDYGebre, A., Smith, C., Webster, J., Saleem, A., Gilani, S. Z., Duque, G., Duncan, E. L., Hong, N. K., Raina, P., Kiel, D. P., Kemp, J. P., Zhong, Y., Daly, R. M., Schousboe, J. T., Leslie, D., Prince, R. L., Harvey, N. C., Lewis, J. R. and Sim, M. (2025). AUTOMATED ABDOMINAL AORTIC CALCIFICATION EXTENT IS ASSOCIATED WITH MUSCLE COMPOSITION, STRENGTH AND SARCOPENIA: THE UK BIOBANK IMAGING STUDY. NEW YORK: SPRINGER. |
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2024 Journal Article The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fractureFaber, Benjamin G., Frysz, Monika, Zheng, Jaiyi, Lin, Huandong, Flynn, Kaitlyn A., Ebsim, Raja, Saunders, Fiona R., Beynon, Rhona, Gregory, Jennifer S., Aspden, Richard M., Harvey, Nicholas C., Lindner, Claudia, Cootes, Timothy, Evans, David M., Smith, George Davey, Gao, Xin, Wang, Sijia, Kemp, John P. and Tobias, Jonathan H. (2024). The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture. Human Molecular Genetics, 34 (3), 207-217. doi: 10.1093/hmg/ddae169 |
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2024 Conference Publication Variation In Hip Shape Amongst The General Population Is Unlikely To Have A Causal Effect On The Development Hip Osteoarthritis: Findings From A GWAS Meta-analysis And Mendelian Randomisation StudyFaber, Ben G., Frysz, Monika, Zheng, Jiayi, Lin, Huandong, Flynn, Kaitlyn, Ebsim, Raja, Saunders, Fiona, Beynon, Rhona, Gregory, Jenny, Aspden, Richard, Harvey, Nicholas, Lindner, Claudia, Cootes, Tim, Smith, George Davey, Evans, David, Gao, Xin, Wang, Sijia, Kemp, John and Tobias, Jon (2024). Variation In Hip Shape Amongst The General Population Is Unlikely To Have A Causal Effect On The Development Hip Osteoarthritis: Findings From A GWAS Meta-analysis And Mendelian Randomisation Study. 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria, 18-21 April 2024. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2024.02.688 |
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2024 Conference Publication Variation in hip shape amongst the general population is unlikely to have a causal effect on the development hip osteoarthritis: findings from a GWAS meta-analysis and Mendelian randomisation studyFaber, Ben G., Frysz, Monika, Zheng, Jiayi, Lin, Huandong, Flynn, Kaitlyn, Ebsim, Raja, Saunders, Fiona, Beynon, Rhona, Gregory, Jenny, Aspden, Richard, Harvey, Nicholas, Lindner, Claudia, Cootes, Tim, Smith, George Davey, Evans, David, Gao, Xin, Wang, Sijia, Kemp, John and Tobias, Jon (2024). Variation in hip shape amongst the general population is unlikely to have a causal effect on the development hip osteoarthritis: findings from a GWAS meta-analysis and Mendelian randomisation study. 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria, 18-21 April 2024. London, United Kingdom: Elsevier. |
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2024 Conference Publication Early findings from the Genetics of Osteoarthritis Endophenotypes Working Group: a genome-wide association meta-analysis of hip osteophytosis identifies IGFBP3Faber, Ben G., Arbeeva, Liubov, Zheng, Jiayi, Beynon, Rhona, Jung, Mijin, Agricola, Rintje, Nelson, Amanda E., Golightly, Yvonne M., Wang, Sijia, Kemp, John, Tobias, Jon, Meurs, Joyce v. and Boer, Cindy (2024). Early findings from the Genetics of Osteoarthritis Endophenotypes Working Group: a genome-wide association meta-analysis of hip osteophytosis identifies IGFBP3. 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria, 18-21 April 2024. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2024.02.715 |
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2024 Journal Article Femoral neck width genetic risk score is a novel independent risk factor for hip fracturesTobias, Jonathan H., Nethander, Maria, Faber, Benjamin G., Heppenstall, Sophie V., Ebsim, Raja, Cootes, Tim, Lindner, Claudia, Saunders, Fiona R., Gregory, Jenny S., Aspden, Richard M., Harvey, Nicholas C., Kemp, John P., Frysz, Monika and Ohlsson, Claes (2024). Femoral neck width genetic risk score is a novel independent risk factor for hip fractures. Journal of Bone and Mineral Research, 39 (3), 241-251. doi: 10.1093/jbmr/zjae002 |
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2023 Conference Publication Multiscale Analysis Identifies Cell Types and Genes Associated with Bone Mineral DensityChai, Ryan C., Lundberg, Mischa, Frysz, Monika, Bassett, J. H. Duncan, Williams, Graham R., Croucher, Peter I. and Kemp, John P. (2023). Multiscale Analysis Identifies Cell Types and Genes Associated with Bone Mineral Density. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Vancouver Canada, Oct 13-16, 2023. OXFORD: OXFORD UNIV PRESS. |
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2023 Conference Publication Femoral Neck Width Genetic Risk Score Is A Novel Independent Risk Factor For Hip FracturesTobias, Jonathan H., Nethander, Maria, Faber, Benjamin F., Heppenstall, Sophie, Ebsim, Raja, Cootes, Timothy, Lidner, Claudia, Saunders, Fiona R., Gregory, Jenny S., Aspden, Richard M., Harvey, Nick C., Kemp, John, Frysz, Monika and Ohlsson, Claes (2023). Femoral Neck Width Genetic Risk Score Is A Novel Independent Risk Factor For Hip Fractures. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Vancouver Canada, Oct 13-16, 2023. OXFORD: OXFORD UNIV PRESS. |
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2023 Conference Publication Identification of genetic risk factors for hip osteoarthritis acting through altered hip shape: findings from a genome-wide association meta-analysis of 43,485 individualsFaber, Benjamin, Frysz, Monika, Zheng, Jiayi, Lin, Huandong, Ebsim, Raja, Saunders, Fiona, Gregory, Jenny, Aspden, Richard, Harvey, Nicholas, Lindner, Claudia, Cootes, Tim, Wang, Sijia, Kemp, John and Tobias, Jonathan (2023). Identification of genetic risk factors for hip osteoarthritis acting through altered hip shape: findings from a genome-wide association meta-analysis of 43,485 individuals. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Vancouver Canada, Oct 13-16, 2023. OXFORD: OXFORD UNIV PRESS. |
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2023 Journal Article The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analysesFaber, Benjamin G., Frysz, Monika, Boer, Cindy G., Evans, Daniel S., Ebsim, Raja, Flynn, Kaitlyn A., Lundberg, Mischa, Southam, Lorraine, Hartley, April, Saunders, Fiona R., Lindner, Claudia, Gregory, Jennifer S., Aspden, Richard M., Lane, Nancy E., Harvey, Nicholas C., Evans, David M., Zeggini, Eleftheria, Davey Smith, George, Cootes, Timothy, Van Meurs, Joyce, Kemp, John P. and Tobias, Jonathan H. (2023). The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses. eBioMedicine, 95 104759, 104759. doi: 10.1016/j.ebiom.2023.104759 |
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2023 Journal Article Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosisMedina-Gomez, Carolina, Mullin, Benjamin H., Chesi, Alessandra, Prijatelj, Vid, Kemp, John P., Shochat-Carvalho, Chen, Trajanoska, Katerina, Wang, Carol, Joro, Raimo, Evans, Tavia E., Schraut, Katharina E., Li-Gao, Ruifang, Ahluwalia, Tarunveer S., Zillikens, M. Carola, Zhu, Kun, Mook-Kanamori, Dennis O., Evans, Daniel S., Nethander, Maria, Knol, Maria J., Thorleifsson, Gudmar, Prokic, Ivana, Zemel, Babette, Broer, Linda, McGuigan, Fiona E., van Schoor, Natasja M., Reppe, Sjur, Pawlak, Mikolaj A., Ralston, Stuart H., van der Velde, Nathalie ... Rivadeneira, Fernando (2023). Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis. Communications Biology, 6 (1) 691, 1-12. doi: 10.1038/s42003-023-04869-0 |
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2023 Journal Article A GWAS meta‐analysis of alpha angle suggests cam‐type morphology may be a specific feature of hip osteoarthritis in older adultsFaber, Benjamin G., Frysz, Monika, Hartley, April E., Ebsim, Raja, Boer, Cindy G., Saunders, Fiona R., Gregory, Jennifer S., Aspden, Richard M, Harvey, Nicholas C., Southam, Lorraine, Giles, William, Le Maitre, Christine L., Wilkinson, J. Mark, van Meurs, Joyce B. J., Zeggini, Eleftheria, Cootes, Timothy, Lindner, Claudia, Kemp, John P., Davey Smith, George and Tobias, Jonathan H. (2023). A GWAS meta‐analysis of alpha angle suggests cam‐type morphology may be a specific feature of hip osteoarthritis in older adults. Arthritis and Rheumatology, 75 (6), 900-909. doi: 10.1002/art.42451 |
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2023 Journal Article Lowering of circulating sclerostin may increase risk of atherosclerosis and its risk factors: evidence from a genome‐wide association meta‐analysis followed by Mendelian randomizationZheng, Jie, Wheeler, Eleanor, Pietzner, Maik, Andlauer, Till F.M., Yau, Michelle S., Hartley, April E., Brumpton, Ben Michael, Rasheed, Humaira, Kemp, John P, Frysz, Monika, Robinson, Jamie, Reppe, Sjur, Prijatelj, Vid, Gautvik, Kaare M., Falk, Louise, Maerz, Winfried, Gergei, Ingrid, Peyser, Patricia A, Kavousi, Maryam, de Vries, Paul S., Miller, Clint L., Bos, Maxime, van der Laan, Sander W., Malhotra, Rajeev, Herrmann, Markus, Scharnagl, Hubert, Kleber, Marcus, Dedoussis, George, Zeggini, Eleftheria ... Tobias, Jonathan H. (2023). Lowering of circulating sclerostin may increase risk of atherosclerosis and its risk factors: evidence from a genome‐wide association meta‐analysis followed by Mendelian randomization. Arthritis & Rheumatology, 75 (10), 1781-1792. doi: 10.1002/art.42538 |
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2023 Conference Publication Expanded genome-wide association study meta-analysis of hip and spine BMD identifies ∼45 novel loci and uncovers widespread pleiotropyLu, Haojie, Frysz, Monika, Lu, Tianyuan, Ohlsson, Claes, Rivadeneira, Fernando, Tobias, Jonathan, Richards, Brent, Kiel, Douglas P., Kemp, John P. and Medina-Gomez, Carolina (2023). Expanded genome-wide association study meta-analysis of hip and spine BMD identifies ∼45 novel loci and uncovers widespread pleiotropy. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Austin Tx, Sep 09-12, 2022. HOBOKEN: WILEY. |
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2023 Conference Publication Describing the genetic architecture of hip shape: findings from UK BiobankFrysz, Monika, Faber, Benjamin, Ebsim, Raja, Saunders, Fiona S., Gregory, Jenny S., Aspden, Richard M., Harvey, Nicholas C., Lindner, Claudia, Cootes, Timothy, Kemp, John P. and Tobias, Jon (2023). Describing the genetic architecture of hip shape: findings from UK Biobank. HOBOKEN: WILEY. |
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2022 Journal Article Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer riskD’Urso, Shannon, Arumugam, Pooja, Weider, Therese, Hwang, Liang-Dar, Bond, Tom A., Kemp, John P., Warrington, Nicole M., Evans, David M., O’Mara, Tracy A. and Moen, Gunn-Helen (2022). Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk. BMC Medicine, 20 (1) 419, 1-17. doi: 10.1186/s12916-022-02585-w |
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2022 Conference Publication A Genome Wide Association Study Of DXA-derived Minimum Joint Space Width Of The Hip Provides Further Insights Into Its Genetic Architecture: Findings From UK BiobankFaber, B., Frysz, M., Ebsim, R., Lundberg, M., Southam, L., Hartley, A., Saunders, F.R., Lindner, C., Gregory, J.S., Aspden, R.M., Harvey, N.C., Zeggini, E., Smith, G. Davey, Cootes, T., Kemp, J.P. and Tobias, J.H. (2022). A Genome Wide Association Study Of DXA-derived Minimum Joint Space Width Of The Hip Provides Further Insights Into Its Genetic Architecture: Findings From UK Biobank. 2022 OARSI World Congress on Osteoarthritis, Online, 7-10 April 2022. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2022.02.051 |
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2022 Journal Article Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal diseaseBergen, Dylan J. M., Tong, Qiao, Shukla, Ankit, Newham, Elis, Zethof, Jan, Lundberg, Mischa, Ryan, Rebecca, Youlten, Scott E., Frysz, Monika, Croucher, Peter I., Flik, Gert, Richardson, Rebecca J., Kemp, John P., Hammond, Chrissy L. and Metz, Juriaan R. (2022). Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease. BMC Biology, 20 (1) 21, 21. doi: 10.1186/s12915-021-01209-8 |
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2022 Journal Article Limb development genes underlie variation in human fingerprint patternsLi, Jinxi, Glover, James D., Zhang, Haiguo, Peng, Meifang, Tan, Jingze, Mallick, Chandana Basu, Hou, Dan, Yang, Yajun, Wu, Sijie, Liu, Yu, Peng, Qianqian, Zheng, Shijie C., Crosse, Edie I., Medvinsky, Alexander, Anderson, Richard A., Brown, Helen, Yuan, Ziyu, Zhou, Shen, Xu, Yanqing, Kemp, John P., Ho, Yvonne Y.W., Loesch, Danuta Z., Wang, Lizhong, Li, Yingxiang, Tang, Senwei, Wu, Xiaoli, Walters, Robin G., Lin, Kuang, Meng, Ruogu ... Wang, Sijia (2022). Limb development genes underlie variation in human fingerprint patterns. Cell, 185 (1), 95-112.e18. doi: 10.1016/j.cell.2021.12.008 |
