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2005

Journal Article

Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model

Begun, Jakob, Sifri, Costi D., Goldman, Samuel, Calderwood, Stephen B. and Ausubel, Frederick M. (2005). Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model. Infection and Immunity, 73 (2), 872-877. doi: 10.1128/IAI.73.2.872-877.2005

Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model

2005

Journal Article

The worm has turned - Microbial virulence modeled in Caenorhabditis elegans

Sifri, CD, Begun, J and Ausubel, FM (2005). The worm has turned - Microbial virulence modeled in Caenorhabditis elegans. Trends in Microbiology, 13 (3), 119-127. doi: 10.1016/j.tim.2005.01.003

The worm has turned - Microbial virulence modeled in Caenorhabditis elegans

2004

Journal Article

Bacterial Resistance of daf-2 Mutants [2] (multiple letters)

Bolm, Maike, Chhatwal, Gursharan S., Jansen, Wouter T. M., Ausubel, Frederick M., Begun, Jakob, Kim, Dennis H., Moy, Terence, Ruvkun, Gary, Calderwood, Stephen B., Sifri, Costi D. and Garsin, Danielle A. (2004). Bacterial Resistance of daf-2 Mutants [2] (multiple letters). Science, 303 (5666)

Bacterial Resistance of daf-2 Mutants [2] (multiple letters)

2003

Journal Article

Long-lived C. elegans daf-2 Mutants are resistant to bacterial pathogens

Garsin, DA, Villanueva, JM, Begun, J, Kim, DH, Sifri, CD, Calderwood, SB, Ruvkun, G and Ausubel, FM (2003). Long-lived C. elegans daf-2 Mutants are resistant to bacterial pathogens. Science, 300 (5627), 1921-1921. doi: 10.1126/science.1080147

Long-lived C. elegans daf-2 Mutants are resistant to bacterial pathogens

2003

Journal Article

Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis

Sifri, Costi D., Begun, Jakob, Ausubel, Frederick M. and Calderwood, Stephen B. (2003). Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infection and Immunity, 71 (4), 2208-2217. doi: 10.1128/IAI.71.4.2208-2217.2003

Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis

2001

Journal Article

Crystal structure of an Xrcc4-DNA ligase IV complex

Sibanda, Bancinyane L., Critchlow, Susan E., Begun, Jake, Pei, Xue Y., Jackson, Stephen P., Blundell, Tom L. and Pellegrini, Luca (2001). Crystal structure of an Xrcc4-DNA ligase IV complex. Nature Structural Biology, 8 (12), 1015-1019. doi: 10.1038/nsb725

Crystal structure of an Xrcc4-DNA ligase IV complex

2001

Journal Article

Getting the adrenaline going: Crystal structure of the adrenaline-synthesizing enzyme PNMT

Martin, J. L., Begun, J., McLeish, M. J., Caine, J. M. and Grunewald, G. L. (2001). Getting the adrenaline going: Crystal structure of the adrenaline-synthesizing enzyme PNMT. Structure, 9 (10), 977-985. doi: 10.1016/S0969-2126(01)00662-1

Getting the adrenaline going: Crystal structure of the adrenaline-synthesizing enzyme PNMT

1999

Journal Article

Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease

Martin, J. L., Begun, J., Schindeler, A., Wickramasinghe, W. A., Alewood, D., Alewood, P. F., Bergman, D. A., Brinkworth, R. I., Abbenante, G., March, D. R., Reid, R. C., Fairlie, D. P. and Armstrong, Richard A. (1999). Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38 (25), 7978-7988. doi: 10.1021/bi990174x

Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease

1996

Journal Article

Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode

March, D. R., Abbenante, G., Bergman, D. A., Brinkworth, R. I., Wickramasinghe, W., Begun, J., Martin, J. L. and Fairlie, D. P. (1996). Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. Journal of The American Chemical Society, 118 (14), 3375-3379. doi: 10.1021/ja953790z

Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode