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2026 Journal Article Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A StreptococcusLu, Lantian, Cruz, Jazmina L. Gonzalez, Giri, Rabina, Zhang, Yuexiao, Bashiri, Sahra, Cadena, Leslie C. Domínguez, Li, Shuhang, Khalil, Zeinab G., Hussein, Waleed M., Wang, Jingwen, Kiong, Jolynn, Lu, Xuehan, Zhang, Jiahui, Lu, Miao, Huang, Wenbin, Kong, Wei Yang, Nahar, Ummey Jannatun, Koirala, Prashamsa, Guo, Zhong, Walden, Patricia, Blumenthal, Antje, Begun, Jakob, Alexandrov, Kirill, Toth, Istvan, Stephenson, Rachel J. and Skwarczynski, Mariusz (2026). Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus. Small, 22 (22) e11459, 1-20. doi: 10.1002/smll.202511459 |
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2026 Journal Article Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging TherapeuticsAn, Yoon‐Kyo, Gilmore, Robert, Radford‐Smith, Graham and Begun, Jakob (2026). Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics. JGH Open, 10 (4) e70394. doi: 10.1002/jgh3.70394 |
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2026 Conference Publication In young people with inflammatory bowel disease, does 904nm laser photobiomodulation influence the gut microbiome?Laakso, E-Liisa, Ewais, Tatjana, Hunt, Matthew, Murtaza, Nida and Begun, Jakob (2026). In young people with inflammatory bowel disease, does 904nm laser photobiomodulation influence the gut microbiome?. Mechanisms of Photobiomodulation Therapy XX, San Francisco, CA United States, 17-23 January 2026. Bellingham, WA United States: SPIE. doi: 10.1117/12.3078349 |
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2026 Journal Article Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologistsChen, Lynna, Ruddick-Collins, Leonie, An, Yoon-Kyo, Baraty, Brandon, Begun, Jakob, Boyapati, Ray K., Bryant, Robert V., Smith, Rebecca L. and Srinivasan, Ashish R. (2026). Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists. Therapeutic Advances in Gastroenterology, 19 17562848261432538. doi: 10.1177/17562848261432538 |
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2026 Journal Article Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trialJairath, Vipul, Vuyyuru, Sudheer K, Zou, Guangyong, Ma, Christopher, Neustifter, Blue, Agboton, Christian, Romo Bautista, Itzel, Allocca, Mariangela, An, Yoon-Kyo, Begun, Jakob, Bryant, Robert V, Danese, Silvio, Dubinsky, Marla, Feagan, Brian G, Freire, Marcelo, Novak, Kerri L, Panaccione, Remo, Pudipeddi, Aviv, Rubin, David T, Sands, Bruce E, Sparrow, Miles P, Taylor, Stuart A, Gecse, Krisztina B, Wilkens, Rune and Maaser, Christian (2026). Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trial. BMJ Open Gastroenterology, 13 (1) e002088, e002088. doi: 10.1136/bmjgast-2025-002088 |
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2026 Conference Publication DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITISHorgan, Kevin, Barnett, Jacqueline, Godovannyi, Artem, Usakiewicz, Jacek, Adur, Malavika, Mayer, Emeran, Begun, Jakob and Gibson, Deanna (2026). DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS. Crohn's and Colitis Congress, Las Vegas Nv, Jan 22-24, 2026. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. |
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2026 Journal Article Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UCLi Wai Suen, Christopher F.D., Choy, Matthew C., Con, Danny, Cheng, Kaylene, Nigro, Julie, Breheney, Kerry, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson., Begun, Jakob, Radford-Smith, Graham L., Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W. ... De Cruz, Peter (2026). Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UC. Gastroenterology, 170 (1), 118-131. doi: 10.1053/j.gastro.2025.07.020 |
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2026 Journal Article Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunctionGiri, Rabina, Lee, Minyi, Magor, Graham, Bergot, Anne-Sophie, He, Yaowu, Kryza, Thomas, Khan, Tashbib, Schreiber, Veronika, Gordon, Robert J., Zagani, Rachid, Hasnain, Sumaira Z., Lourie, Rohan, Ewing, Adam, Hooper, John D., Thomas, Ranjeny, Florin, Timothy H., Perkins, Andrew, Gala, Manish and Begun, Jakob (2026). Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction. Cellular and Molecular Gastroenterology and Hepatology, 20 (2) 101659, 1-20. doi: 10.1016/j.jcmgh.2025.101659 |
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2025 Journal Article Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfactionFernandes, Richard Gareth, Khoo, Emi, Jensen Harris, Heidi, Gilmore, Robert, Khaing, Myat Myat, Ennever, Jenny, Mullen, Kaity, Begun, Jakob and An, Yoon-Kyo (2025). Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction. Journal of Crohn's and Colitis, 19 (12) jjaf221. doi: 10.1093/ecco-jcc/jjaf221 |
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2025 Journal Article Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD ConsortiumAn, Yoon‐Kyo, Lindsay, Niamh, Allan, Natalie, Khoo, Emi, Fernandes, Richard, Gilmore, Robert, Amiss, Anna, Pham, Hai, Ooi, Soong‐Yuan, Thin, Lena, Lightowler, Daniel, Connor, Susan J., Williams, Astrid, De Cruz, Peter, Li Wai Suen, Christopher F. D., Kariyawasam, Viraj, Mitrev, Nikola, Ghaly, Simon, Andrews, Jane M., Christensen, Britt, Sparrow, Miles P., White, Lauren S., Bryant, Robert, Ding, Nik S., Leong, Rupert W., Van Langenberg, Daniel R., Seltenreich, Hansjoerg, Subramaniam, Kavitha, Radford‐Smith, Graham and Begun, Jakob (2025). Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium. JGH Open, 9 (12) e70322, e70322. doi: 10.1002/jgh3.70322 |
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2025 Journal Article Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohortWu, Rodger, Rivas, Consuelo, Su, Wai Kin, Deschenes, Renée, Wilson, William, Pipicella, Joseph L., Connor, Susan J., Andrews, Jane M., An, Yoon-Kyo, Begun, Jakob, Boyapati, Ray, Dutt, Shoma, Gearry, Richard B, Ghaly, Simon, Haifer, Craig, Lawrance, Ian C, Lynch, Kate, Moore, Gregory, Radford-Smith, Graham, Shahzad, Asif, Schultz, Michael, Su, Heidi, Ng, Watson, Verdon, Christine, Walker, Gareth and Wark, Gabrielle (2025). Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort. JGH Open, 9 (12) e70308, 1-14. doi: 10.1002/jgh3.70308 |
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2025 Conference Publication Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophagesBisht, Kavita, Zhong, Ruiqing, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Tang, Yifu, Giri, Rabina, Amiss, Anna, Alexander, Kylie, Millard, Susan, Pettit, Allison, Winkler, Ingrid, Begun, Jakob and Levesque, Jean-Pierre (2025). Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages. 54th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Kumamoto, Japan, 24-27 September 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2025.105131 |
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2025 Journal Article Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from AustralasiaFernandes, Richard Gareth, Kim, Dong Hyun, Ruddick-Collins, Leonie, Vasudevan, Abhinav, Brownson, Anthony Robert, Ngoi, Benjamin, Lin, Chun-Chi, Haifer, Craig, Kim, Dae Sung, Swe, Ei, Wright, Emily Kate, Song, Eun Mi, Mahy, Gillian, Moore, Gregory Thomas, Lee, Hyun Seok, Kim, Hyun Soo, Zhang, Jennifer, Yan Mak, Joyce Wing, Lee, Jun, Lynch, Kate, Gazelakis, Kathryn, Rice, Katie, Kim, Kyeong Ok, Liu, Jing, Lilian Bracken, Lucy Mary, Garg, Mayur, Schultz, Michael, Clark, Nicholas, Cao, Qian ... An, Yoon-Kyo (2025). Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2025.10.019 |
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2025 Journal Article Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigationsTan, Wei-Lian, Khoo, Emi, Khaing, Myat-Myat, Barr, Emily, Fernandes, Richard G., Pham, Hai, An, Yoon-Kyo and Begun, Jakob (2025). Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations. Journal of Gastroenterology and Hepatology, 40 (10), 2472-2481. doi: 10.1111/jgh.70019 |
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2025 Journal Article Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathyCai, Benjamin, Giri, Rabina, Cameron, Amy J., Rahman, M. Arifur, Small, Annabelle, Altmann, Christopher, Lim, Yenkai, Rehaume, Linda M., Morrison, Mark, Wechalekar, Mihir D., Begun, Jakob, Bergot, Anne-Sophie and Thomas, Ranjeny (2025). Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy. JCI Insight, 10 (17) e188028, 1-19. doi: 10.1172/jci.insight.188028 |
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2025 Conference Publication Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assayKrause, Lutz, Boyd, Joel, Cooper, Martha, Pribyl, Alena, An, Yoon-Kyo, Begun, Jakob and Cuive, Paraic O. (2025). Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assay. HOBOKEN: WILEY. |
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2025 Journal Article IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, AustraliaMahadevan, Uma, Jairath, Vipul, Begun, Jakob, Pudipeddi, Aviv, Garg, Mayur, De Cruz, Peter, Li Wai Suen, Christopher F. D., Choy, Matthew C., Con, Danny, Vaughan, Rose, Chetwood, John D., Clark, David A., Haifer, Craig, Sparrow, Miles P., Leong, Rupert and Mountifield, Réme (2025). IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, Australia. Journal of Gastroenterology and Hepatology, 40 (S3), 3-22. doi: 10.1111/jgh.70020 |
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2025 Conference Publication The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patientsHuynh, David, Khoo, Emi, Anandan, Aathavan Shanmuga and Begun, Jakob (2025). The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patients. HOBOKEN: WILEY. |
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2025 Conference Publication Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UCSuen, Christopher F. D. Li Wai, Choy, Matthew C., Con, Danny, Driver, Kate, Bruen, Dylan, Glason, Joshua, Bonelli, Fabrizio, Bittar, Intissar, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham, Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S. ... De Cruz, Peter (2025). Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UC. HOBOKEN: WILEY. |
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2025 Conference Publication Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activityKhaing, Myat Myat, Fernandes, Richard, An, Yoon-Kyo, Baraty, Brandon, Bryant, Robert V., Ghaly, Simon, Smith, Rebecca, Srinivasan, Ashish, Hay, Karen and Begun, Jakob (2025). Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activity. HOBOKEN: WILEY. |
