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2025 Conference Publication Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's diseaseYeo, Jeremy, Gilmore, Robert, Pham, Lily, Fernandes, Richard, Nguyen, Andrew, Vasudevan, Abhinav, Parkash, Nikita, Moore, Gregory, Christmas, Michael, White, Lauren, Subhaharan, Deloshaan, Mohsen, Waled, Ramaswamy, Pradeep Kakkadasam, Massouridis, Benjamin, Sparrow, Miles P., Ding, John, Lin, Alan, Clark, Nicholas, An, Yoon and Begun, Jakob (2025). Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease. World Gastroenterology Organisation and Gastroenterological Society of Australia World Congress of Gastroenterology @ Australian Gastroenterology Week 2025, Melbourne, VIC, Australia, 19-22 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/jgh.70044 |
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2025 Conference Publication Complete disease clearance as a novel composite endpoint to predict long-term relapse in vedolizumab-treated patients with ulcerative colitis: A post-hoc analysis from the VIEWS randomised controlled trialPudipeddi, Aviv, Paramsothy, Sudarshan, Kariyawasam, Viraj, Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon-Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark G., De Cruz, Peter, Fung, Caroline, Redmond, Diane, Chan, Webber, Mourad, Fadi, Kermeen, Melissa and Leong, Rupert W. (2025). Complete disease clearance as a novel composite endpoint to predict long-term relapse in vedolizumab-treated patients with ulcerative colitis: A post-hoc analysis from the VIEWS randomised controlled trial. HOBOKEN: WILEY. |
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2025 Conference Publication Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assayKrause, Lutz, Boyd, Joel, Cooper, Martha, Pribyl, Alena, An, Yoon-Kyo, Begun, Jakob and Cuive, Paraic O. (2025). Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assay. HOBOKEN: WILEY. |
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2025 Journal Article IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, AustraliaMahadevan, Uma, Jairath, Vipul, Begun, Jakob, Pudipeddi, Aviv, Garg, Mayur, De Cruz, Peter, Li Wai Suen, Christopher F. D., Choy, Matthew C., Con, Danny, Vaughan, Rose, Chetwood, John D., Clark, David A., Haifer, Craig, Sparrow, Miles P., Leong, Rupert and Mountifield, Réme (2025). IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, Australia. Journal of Gastroenterology and Hepatology, 40 (S3), 3-22. doi: 10.1111/jgh.70020 |
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2025 Conference Publication The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patientsHuynh, David, Khoo, Emi, Anandan, Aathavan Shanmuga and Begun, Jakob (2025). The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patients. HOBOKEN: WILEY. |
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2025 Conference Publication Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UCSuen, Christopher F. D. Li Wai, Choy, Matthew C., Con, Danny, Driver, Kate, Bruen, Dylan, Glason, Joshua, Bonelli, Fabrizio, Bittar, Intissar, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham, Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S. ... De Cruz, Peter (2025). Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UC. HOBOKEN: WILEY. |
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2025 Conference Publication Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activityKhaing, Myat Myat, Fernandes, Richard, An, Yoon-Kyo, Baraty, Brandon, Bryant, Robert V., Ghaly, Simon, Smith, Rebecca, Srinivasan, Ashish, Hay, Karen and Begun, Jakob (2025). Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activity. HOBOKEN: WILEY. |
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2025 Conference Publication Early serum and faecal infliximab levels predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from the PREDICT-UC randomised controlled trialSuen, Christopher F. D. Li Wai, Choy, Matthew C., Con, Danny, Cheng, Kaylene, Nigro, Julie, Breheney, Kerry, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham L., Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W. ... De Cruz, Peter (2025). Early serum and faecal infliximab levels predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from the PREDICT-UC randomised controlled trial. HOBOKEN: WILEY. |
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2025 Journal Article Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort studyGilmore, Robert, Fernandes, Richard, Hartley, Imogen, Arzivian, Arteen, Leong, Rupert, Andrew, Bridgette, Vasudevan, Abhinav, Greeve, Tessa, Moore, Gregory Thomas, Kim, Steven, Lightowler, Daniel, Singh, Abhey, Mahy, Gillian, Mithanthaya, Aditya, Venugopaul, Kannan, Han, Sangwoo, Bryant, Robert, West, Jack, Segal, Jonathan, Christensen, Britt, Corte, Crispin, Ding, Nik, An, Yoon-Kyo and Begun, Jakob (2025). Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study. Intestinal Research, 23 (3), 347-357. doi: 10.5217/ir.2024.00127 |
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2025 Journal Article Expert position statement: defining the role of intestinal ultrasound in assessing constipation and faecal loadingMathias, Ryan M., Goodsall, Thomas M., Parker, Claire E., Day, Alice S., An, Yoon K., Baraty, Brandon, Basnayake, Chamara, Begun, Jakob, Boyapati, Ray K., Burgell, Rebecca, Dolinger, Michael T., Maconi, Giovanni, Novak, Kerri L., Sagami, Shintaro, Smith, Rebecca L., Srinivasan, Ashish R., Taylor, Stuart A., Jairath, Vipul, Ma, Christopher and Bryant, Robert V. (2025). Expert position statement: defining the role of intestinal ultrasound in assessing constipation and faecal loading. Alimentary Pharmacology and Therapeutics, 62 (8), 799-808. doi: 10.1111/apt.70250 |
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2025 Journal Article Upadacitinib and vedolizumab combination therapy for the management of refractory ulcerative colitis and Crohn’s diseaseGilmore, Robert, Murali, Amrutha, Etchegaray, Amirah, Swe, Ei, An, Yoon-Kyo and Begun, Jakob (2025). Upadacitinib and vedolizumab combination therapy for the management of refractory ulcerative colitis and Crohn’s disease. Intestinal Research, 23 (4), 475-482. doi: 10.5217/ir.2024.00174 |
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2025 Conference Publication Patterns And Predictors Of Steroid Use In People With Ibd In Routine Care Across ANZRivas, Consuelo, Su, Wai Kin, Wilson, William E., Ng, Watson, Ghaly, Simon, Walker, Gareth, Forbes, Angela J., Su, Heidi, Schultz, Michael, Lawrance, Ian C., Dutt, Shoma, Brett, Laurel, Begun, Jakob, Lynch, Kate D., Andrews, Jane M. and Connor, Susan J. (2025). Patterns And Predictors Of Steroid Use In People With Ibd In Routine Care Across ANZ. Digestive Disease Week (DDW) 2025, San Diego, CA United States, 3-6 August 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(25)03886-7 |
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2025 Conference Publication Correlation Of Biochemical, Endoscopic And Histologic Endpoints In Vedolizumab-treated Patients With Ulcerative Colitis: A Post-hoc Analysis From The Views Randomised Controlled TrialPudipeddi, Aviv, Paramsothy, Sudarshan, Kariyawasam, Viraj C., Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon-Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark, De Cruz, Peter, Fung, Caroline L., Redmond, Diane, Chan, Pak Wo, Mourad, Fadi H., Kermeen, Melissa and Leong, Rupert (2025). Correlation Of Biochemical, Endoscopic And Histologic Endpoints In Vedolizumab-treated Patients With Ulcerative Colitis: A Post-hoc Analysis From The Views Randomised Controlled Trial. Digestive Disease Week (DDW) 2025, San Diego, CA United States, 3-6 August 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(25)03004-5 |
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2025 Conference Publication Extensive Disease Clearance As A Novel Composite Endpoint To Predict Long-term Relapse In Vedolizumab-treated Patients With Ulcerative Colitis: A Post-hoc Analysis From The Views Randomised Controlled TrialPudipeddi, Aviv, Paramsothy, Sudarshan, Kariyawasam, Viraj C., Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon-Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark, De Cruz, Peter, Fung, Caroline L., Redmond, Diane, Chan, Pak Wo, Mourad, Fadi H., Kermeen, Melissa and Leong, Rupert (2025). Extensive Disease Clearance As A Novel Composite Endpoint To Predict Long-term Relapse In Vedolizumab-treated Patients With Ulcerative Colitis: A Post-hoc Analysis From The Views Randomised Controlled Trial. Digestive Disease Week (DDW) 2025, San Diego, CA United States, 3-6 August 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(25)02960-9 |
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2025 Conference Publication Comparative Accuracy And Reliability Of Handheld Versus Cart-based Ultrasound In Assessing Inflammatory Bowel Disease ActivityKhaing, Myat Myat, Fernandes, Richard G., An, Yoon-Kyo, Baraty, Brandon, Bryant, Robert V., Ghaly, Simon, Smith, Rebecca, Srinivasan, Ashish, Hay, Karen and Begun, Jakob (2025). Comparative Accuracy And Reliability Of Handheld Versus Cart-based Ultrasound In Assessing Inflammatory Bowel Disease Activity. Digestive Disease Week (DDW) 2025, San Diego, CA United States, 3-6 August 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(25)03008-2 |
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2025 Journal Article Colon‐targeted complement C5a1 receptor inhibition using pH‐sensitive nanoparticles ameliorates experimental colitisCui, Cedric S., Lerskiatiphanich, Titaya, Li, Xaria X., Giri, Rabina, Liu, Ning, Kumar, Vinod, Whittaker, Andrew K., Han, Felicity Y., Clark, Richard J., Begun, Jakob, Lee, John D. and Woodruff, Trent M. (2025). Colon‐targeted complement C5a1 receptor inhibition using pH‐sensitive nanoparticles ameliorates experimental colitis. British Journal of Pharmacology, 182 (16), 3852-3869. doi: 10.1111/bph.70056 |
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2025 Journal Article The durability of anti-TNF therapy for Crohn’s Disease is higher in anti-TNF naïve patients and increases with proactive therapeutic drug monitoringGilmore, Robert, Fernandes, Richard, Schildkraut, Tamar, Joshi, Riddhi, Lin, Lyman, Vorgin, Sara, Etchegaray, Amirah, Shanmuga Anandan, Aathavan, Tambakis, George, Loebenstein, Moshe, An, Yoon-Kyo, Begun, Jakob and Wright, Emily K (2025). The durability of anti-TNF therapy for Crohn’s Disease is higher in anti-TNF naïve patients and increases with proactive therapeutic drug monitoring. Crohn's and Colitis 360, 7 (2) otaf028, 1-9. doi: 10.1093/crocol/otaf028 |
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2025 Journal Article SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolomeTillett, Bree J., Dwiyanto, Jacky, Secombe, Kate R., George, Thomas, Zhang, Vivian, Anderson, Dovile, Duggan, Emily, Giri, Rabina, Loo, Dorothy, Stoll, Thomas, Morrison, Mark, Begun, Jakob, Hill, Michelle M., Gurzov, Esteban N., Bell, Kirstine J., Saad, Sonia, Barlow, Christopher K., Creek, Darren J., Chong, Chun Wie, Mariño, Eliana and Hamilton-Williams, Emma E. (2025). SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome. Nature Communications, 16 (1) 2893, 1-20. doi: 10.1038/s41467-025-58319-y |
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2025 Conference Publication Janus Kinase Inhibitors for the Management of Acute Severe Ulcerative Colitis: A Multicenter StudyGilmore, Robert, Fernandes, Richard, Tambakis, George, Etechegaray, Amirah, Walker, Gareth, Subhaharan, Deloshaan, Mohsen, Waled, Thin, Lena, Chin, Simone, Con, Danny, De Cruz, Peter, Demase, Kathryn, Sparrow, Miles, Lucas, Sarah, Garg, Mayur, Bryant, Robert, Begun, Jakob and An, Yoon-Kyo (2025). Janus Kinase Inhibitors for the Management of Acute Severe Ulcerative Colitis: A Multicenter Study. HOBOKEN: WILEY. |
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2025 Conference Publication Clinical outcomes and predictive factors differ in acute severe ulcerative colitis for East Asian and Western patientsKim, E. S., Lee, H. S., Kim, D. H., Kim, H. S., Park, S. H., Kim, K. O., Jang, B., Kim, D. S., Lee, Y. J., Song, E. M., Kim, S. J., Lee, J., Yang, C. H., Sagami, S., Kobayashi, T., Mak, J., Liu, J., Cao, Q., Lin, W. C., Wei, S. C., Rice, K., An, Y. K., Begun, J., Ruddick-Collins, L., Fernandes, R. G., Gilmore, R., Vasudevan, A., Zhang, J., Brownson, A. ... Garg, M. (2025). Clinical outcomes and predictive factors differ in acute severe ulcerative colitis for East Asian and Western patients. 20th Congress of ECCO, Berlin, Germany, 19-22 February 2025. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjae190.0082 |
