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2026 Journal Article TREAT-TO-TARGET IN INFLAMMATORY BOWEL DISEASE: PROMISE, PERILS, AND THE PATH FORWARDSingh, Siddharth, Nardone, Olga Maria, Allocca, Mariangela, Yuan, Yuhong, Begun, Jakob, Hou, Jason K., Shehab, Mohammad, Kobayashi, Taku, Ahuja, Vineet, Dignass, Axel and Jairath, Vipul (2026). TREAT-TO-TARGET IN INFLAMMATORY BOWEL DISEASE: PROMISE, PERILS, AND THE PATH FORWARD. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2026.09.033 |
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2026 Journal Article Adherens junction dysfunction in intestinal inflammation revisitedHaslam, Fabienne, Begun, Jakob and Yap, Alpha S. (2026). Adherens junction dysfunction in intestinal inflammation revisited. Molecular Biology of the Cell, 37 (10) mbc.E25-09-0426, 1-6. doi: 10.1091/mbc.e25-09-0426 |
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2026 Journal Article Janus kinase inhibitors for acute severe ulcerative colitis: comparing upadacitinib to tofacitinib and rescue to sequential salvage therapyGilmore, R., Fernandes, R., Goetz, N., Chin, S., Con, D., De Cruz, P., Demase, K., Sparrow, M. P., Lucas, S., Garg, M., Tuttle, Z., Clark, N., Tassone, D., Ding, N., Loebenstein, M., Nguyen, A., Moore, G. T., Thin, L., MacFarlane, K., Lynch, K. D., Subhaharan, D., Mohsen, W., Haig, A., Day, M., White, L., Baker, J., Venugopal, K., Tandon, B., Bryant, R. V. ... An, Y. K. (2026). Janus kinase inhibitors for acute severe ulcerative colitis: comparing upadacitinib to tofacitinib and rescue to sequential salvage therapy. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2026.09.017 |
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2026 Journal Article The Burden of Viral Respiratory Infections in Immunosuppressed Inflammatory Bowel Disease PatientsHuynh, D., Khoo, E., Shanmuga Anandan, A. and Begun, J. (2026). The Burden of Viral Respiratory Infections in Immunosuppressed Inflammatory Bowel Disease Patients. JGH Open, 10 (8) e70456, e70456-e70456. doi: 10.1002/jgh3.70456 |
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2026 Journal Article Study of TOfacitinib for the treatment of chronic PouchITis (STOPit): a multi-centre open label induction with randomised, double blind, placebo-controlled maintenance trialKhoo, Emi, Holtmann, Gerald and Begun, Jakob (2026). Study of TOfacitinib for the treatment of chronic PouchITis (STOPit): a multi-centre open label induction with randomised, double blind, placebo-controlled maintenance trial. BMJ Open, 16 (7) e118940, e118940-7. doi: 10.1136/bmjopen-2026-118940 |
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2026 Journal Article Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from AustralasiaFernandes, Richard Gareth, Kim, Dong Hyun, Ruddick-Collins, Leonie, Vasudevan, Abhinav, Brownson, Anthony Robert, Ngoi, Benjamin, Lin, Chun-Chi, Haifer, Craig, Kim, Dae Sung, Swe, Ei, Wright, Emily Kate, Song, Eun Mi, Mahy, Gillian, Moore, Gregory Thomas, Lee, Hyun Seok, Kim, Hyun Soo, Zhang, Jennifer, Yan Mak, Joyce Wing, Lee, Jun, Lynch, Kate, Gazelakis, Kathryn, Rice, Katie, Kim, Kyeong Ok, Liu, Jing, Lilian Bracken, Lucy Mary, Garg, Mayur, Schultz, Michael, Clark, Nicholas, Cao, Qian ... An, Yoon-Kyo (2026). Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia. Clinical Gastroenterology and Hepatology, 24 (7), 1916-1927. doi: 10.1016/j.cgh.2025.10.019 |
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2026 Journal Article Never‐smoking is associated with histologic remission in ulcerative colitis: a post‐hoc analysis of the VIEWS randomised controlled trialPudipeddi, Aviv, Pajes, Nico, Paramsothy, Sudarshan, Kariyawasam, Viraj, Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon‐Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark G., De Cruz, Peter, Fung, Caroline Lan‐San, Redmond, Diane, Chan, Webber, Mourad, Fadi H., Kermeen, Melissa and Leong, Rupert W. (2026). Never‐Smoking Is Associated With Histologic Remission in Ulcerative Colitis: A Post‐Hoc Analysis of the VIEWS Randomised Controlled Trial. JCC Plus, 1 (4) e70051. doi: 10.1002/jcc5.70051 |
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2026 Journal Article New Diagnostic Criteria for Acute Severe Ulcerative Colitis in the Modern Treatment Era: A Modified Delphi Consensus by REFINED-ASUCRaine, Tim, Peyrin-Biroulet, Laurent, Begun, Jakob, Biedermann, Luc, Blumenstein, Irina, Cheifetz, Adam S., Colombel, Jean-Frederic, Dulai, Parambir S., Gecse, Krisztina B., Jairath, Vipul, Nakase, Hiroshi, Panaccione, Remo, Reinisch, Walter, Verstockt, Bram and Higgins, Peter D.R. (2026). New Diagnostic Criteria for Acute Severe Ulcerative Colitis in the Modern Treatment Era: A Modified Delphi Consensus by REFINED-ASUC. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2026.07.011 |
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2026 Journal Article Distinct predictive factors for acute severe ulcerative colitis in East Asian and Western populationsKim, Eun Soo, Kim, Dong Hyun, Kim, Seong-Jung, Park, Sang Hyoung, Lee, Hyun Seok, Kim, Sung Kook, Kim, Hyun Soo, Lee, Jun, Kim, Kyeong Ok, Jang, Byung Ik, Lee, Yoo Jin, Song, Eun Mi, Kim, Dae Sung, Lin, Chun-Chi, Mak, Joyce Wing Yan, Liu, Jing, Cao, Qian, Wei, Shu-Chen, Lin, Wei-Chen, Hsu, Wen-Hung, Sagami, Shintaro, Kobayashi, Taku, Fernandes, Richard G, Gilmore, Robert, An, Yoon-Kyo, Begun, Jakob, Rice, Katie, Ruddick-Collins, Leonie, Vasudevan, Abhinav ... Australia New Zealand IBD Consortium (ANZIBDC) and the Asian Organization for Crohn’s and Colitis (AOCC) (2026). Distinct predictive factors for acute severe ulcerative colitis in East Asian and Western populations. Inflammatory Bowel Diseases izag098. doi: 10.1093/ibd/izag098 |
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2026 Journal Article Extended high‐dose tofacitinib induction improves clinical response in ulcerative colitis: a multicenter cohort studyGilmore, R., Pham, T., Fernandes, R. G., Wright, E. K., Lo, S., Rosella, O., De Cruz, P., Andrew, B., Vasudevan, A., Gazelakis, K., Moore, G. T., Thin, L., Au, K., Ghaly, S., Chen, C., Mohsen, W., Goodwin, T., Sparrow, M. P., Ward, M. G., Chew, M., Garg, M., Shelton, E., Lawrance, I. C., Thorat, A., da Fonseca Pereira, C., Begun, J. and An, Y. K. (2026). Extended high‐dose tofacitinib induction improves clinical response in ulcerative colitis: a multicenter cohort study. JGH Open, 10 (5) e70410, 5. doi: 10.1002/jgh3.70410 |
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2026 Journal Article Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A StreptococcusLu, Lantian, Cruz, Jazmina L. Gonzalez, Giri, Rabina, Zhang, Yuexiao, Bashiri, Sahra, Cadena, Leslie C. Domínguez, Li, Shuhang, Khalil, Zeinab G., Hussein, Waleed M., Wang, Jingwen, Kiong, Jolynn, Lu, Xuehan, Zhang, Jiahui, Lu, Miao, Huang, Wenbin, Kong, Wei Yang, Nahar, Ummey Jannatun, Koirala, Prashamsa, Guo, Zhong, Walden, Patricia, Blumenthal, Antje, Begun, Jakob, Alexandrov, Kirill, Toth, Istvan, Stephenson, Rachel J. and Skwarczynski, Mariusz (2026). Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus. Small, 22 (22) e11459, 1-20. doi: 10.1002/smll.202511459 |
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2026 Journal Article Advances in Crohn's disease: A comprehensive review of pathophysiology, diagnosis, and emerging therapeuticsAn, Yoon‐Kyo, Gilmore, Robert, Radford‐Smith, Graham and Begun, Jakob (2026). Advances in Crohn's disease: A comprehensive review of pathophysiology, diagnosis, and emerging therapeutics. JGH Open, 10 (4) e70394, 1-13. doi: 10.1002/jgh3.70394 |
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2026 Journal Article Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trialJairath, Vipul, Vuyyuru, Sudheer K, Zou, Guangyong, Ma, Christopher, Neustifter, Blue, Agboton, Christian, Romo Bautista, Itzel, Allocca, Mariangela, An, Yoon-Kyo, Begun, Jakob, Bryant, Robert V, Danese, Silvio, Dubinsky, Marla, Feagan, Brian G, Freire, Marcelo, Novak, Kerri L, Panaccione, Remo, Pudipeddi, Aviv, Rubin, David T, Sands, Bruce E, Sparrow, Miles P, Taylor, Stuart A, Gecse, Krisztina B, Wilkens, Rune and Maaser, Christian (2026). Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trial. BMJ Open Gastroenterology, 13 (1) e002088, 1-13. doi: 10.1136/bmjgast-2025-002088 |
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2026 Journal Article Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UCLi Wai Suen, Christopher F.D., Choy, Matthew C., Con, Danny, Cheng, Kaylene, Nigro, Julie, Breheney, Kerry, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson., Begun, Jakob, Radford-Smith, Graham L., Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W. ... De Cruz, Peter (2026). Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UC. Gastroenterology, 170 (1), 118-131. doi: 10.1053/j.gastro.2025.07.020 |
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2026 Journal Article Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunctionGiri, Rabina, Lee, Minyi, Magor, Graham, Bergot, Anne-Sophie, He, Yaowu, Kryza, Thomas, Khan, Tashbib, Schreiber, Veronika, Gordon, Robert J., Zagani, Rachid, Hasnain, Sumaira Z., Lourie, Rohan, Ewing, Adam, Hooper, John D., Thomas, Ranjeny, Florin, Timothy H., Perkins, Andrew, Gala, Manish and Begun, Jakob (2026). Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction. Cellular and Molecular Gastroenterology and Hepatology, 20 (2) 101659, 1-20. doi: 10.1016/j.jcmgh.2025.101659 |
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2026 Journal Article Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologistsChen, Lynna, Ruddick-Collins, Leonie, An, Yoon-Kyo, Baraty, Brandon, Begun, Jakob, Boyapati, Ray K., Bryant, Robert V., Smith, Rebecca L. and Srinivasan, Ashish R. (2026). Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists. Therapeutic Advances in Gastroenterology, 19 17562848261432538, 1-11. doi: 10.1177/17562848261432538 |
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2025 Journal Article Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfactionFernandes, Richard Gareth, Khoo, Emi, Jensen Harris, Heidi, Gilmore, Robert, Khaing, Myat Myat, Ennever, Jenny, Mullen, Kaity, Begun, Jakob and An, Yoon-Kyo (2025). Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction. Journal of Crohn's and Colitis, 19 (12) jjaf221. doi: 10.1093/ecco-jcc/jjaf221 |
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2025 Journal Article Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohortWu, Rodger, Rivas, Consuelo, Su, Wai Kin, Deschenes, Renée, Wilson, William, Pipicella, Joseph L., Connor, Susan J., Andrews, Jane M., An, Yoon-Kyo, Begun, Jakob, Boyapati, Ray, Dutt, Shoma, Gearry, Richard B, Ghaly, Simon, Haifer, Craig, Lawrance, Ian C, Lynch, Kate, Moore, Gregory, Radford-Smith, Graham, Shahzad, Asif, Schultz, Michael, Su, Heidi, Ng, Watson, Verdon, Christine, Walker, Gareth and Wark, Gabrielle (2025). Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort. JGH Open, 9 (12) e70308, 1-14. doi: 10.1002/jgh3.70308 |
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2025 Journal Article Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD ConsortiumAn, Yoon‐Kyo, Lindsay, Niamh, Allan, Natalie, Khoo, Emi, Fernandes, Richard, Gilmore, Robert, Amiss, Anna, Pham, Hai, Ooi, Soong‐Yuan, Thin, Lena, Lightowler, Daniel, Connor, Susan J., Williams, Astrid, De Cruz, Peter, Li Wai Suen, Christopher F. D., Kariyawasam, Viraj, Mitrev, Nikola, Ghaly, Simon, Andrews, Jane M., Christensen, Britt, Sparrow, Miles P., White, Lauren S., Bryant, Robert, Ding, Nik S., Leong, Rupert W., Van Langenberg, Daniel R., Seltenreich, Hansjoerg, Subramaniam, Kavitha, Radford‐Smith, Graham and Begun, Jakob (2025). Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium. JGH Open, 9 (12) e70322, e70322. doi: 10.1002/jgh3.70322 |
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2025 Journal Article Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigationsTan, Wei-Lian, Khoo, Emi, Khaing, Myat-Myat, Barr, Emily, Fernandes, Richard G., Pham, Hai, An, Yoon-Kyo and Begun, Jakob (2025). Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations. Journal of Gastroenterology and Hepatology, 40 (10), 2472-2481. doi: 10.1111/jgh.70019 |
