Skip to menu Skip to content Skip to footer

2026

Journal Article

Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus

Lu, Lantian, Cruz, Jazmina L. Gonzalez, Giri, Rabina, Zhang, Yuexiao, Bashiri, Sahra, Cadena, Leslie C. Domínguez, Li, Shuhang, Khalil, Zeinab G., Hussein, Waleed M., Wang, Jingwen, Kiong, Jolynn, Lu, Xuehan, Zhang, Jiahui, Lu, Miao, Huang, Wenbin, Kong, Wei Yang, Nahar, Ummey Jannatun, Koirala, Prashamsa, Guo, Zhong, Walden, Patricia, Blumenthal, Antje, Begun, Jakob, Alexandrov, Kirill, Toth, Istvan, Stephenson, Rachel J. and Skwarczynski, Mariusz (2026). Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus. Small, 22 (22) e11459, 1-20. doi: 10.1002/smll.202511459

Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus

2026

Journal Article

Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics

An, Yoon‐Kyo, Gilmore, Robert, Radford‐Smith, Graham and Begun, Jakob (2026). Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics. JGH Open, 10 (4) e70394. doi: 10.1002/jgh3.70394

Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics

2026

Conference Publication

In young people with inflammatory bowel disease, does 904nm laser photobiomodulation influence the gut microbiome?

Laakso, E-Liisa, Ewais, Tatjana, Hunt, Matthew, Murtaza, Nida and Begun, Jakob (2026). In young people with inflammatory bowel disease, does 904nm laser photobiomodulation influence the gut microbiome?. Mechanisms of Photobiomodulation Therapy XX, San Francisco, CA United States, 17-23 January 2026. Bellingham, WA United States: SPIE. doi: 10.1117/12.3078349

In young people with inflammatory bowel disease, does 904nm laser photobiomodulation influence the gut microbiome?

2026

Journal Article

Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists

Chen, Lynna, Ruddick-Collins, Leonie, An, Yoon-Kyo, Baraty, Brandon, Begun, Jakob, Boyapati, Ray K., Bryant, Robert V., Smith, Rebecca L. and Srinivasan, Ashish R. (2026). Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists. Therapeutic Advances in Gastroenterology, 19 17562848261432538. doi: 10.1177/17562848261432538

Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists

2026

Conference Publication

DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS

Horgan, Kevin, Barnett, Jacqueline, Godovannyi, Artem, Usakiewicz, Jacek, Adur, Malavika, Mayer, Emeran, Begun, Jakob and Gibson, Deanna (2026). DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS. Crohn's and Colitis Congress, Las Vegas Nv, Jan 22-24, 2026. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.

DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS

2026

Journal Article

Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trial

Jairath, Vipul, Vuyyuru, Sudheer K, Zou, Guangyong, Ma, Christopher, Neustifter, Blue, Agboton, Christian, Romo Bautista, Itzel, Allocca, Mariangela, An, Yoon-Kyo, Begun, Jakob, Bryant, Robert V, Danese, Silvio, Dubinsky, Marla, Feagan, Brian G, Freire, Marcelo, Novak, Kerri L, Panaccione, Remo, Pudipeddi, Aviv, Rubin, David T, Sands, Bruce E, Sparrow, Miles P, Taylor, Stuart A, Gecse, Krisztina B, Wilkens, Rune and Maaser, Christian (2026). Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trial. BMJ Open Gastroenterology, 13 (1) e002088, e002088. doi: 10.1136/bmjgast-2025-002088

Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn’s disease: rationale, design and protocol for the randomised controlled VECTORS trial

2026

Journal Article

Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction

Giri, Rabina, Lee, Minyi, Magor, Graham, Bergot, Anne-Sophie, He, Yaowu, Kryza, Thomas, Khan, Tashbib, Schreiber, Veronika, Gordon, Robert J., Zagani, Rachid, Hasnain, Sumaira Z., Lourie, Rohan, Ewing, Adam, Hooper, John D., Thomas, Ranjeny, Florin, Timothy H., Perkins, Andrew, Gala, Manish and Begun, Jakob (2026). Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction. Cellular and Molecular Gastroenterology and Hepatology, 20 (2) 101659, 1-20. doi: 10.1016/j.jcmgh.2025.101659

Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction

2026

Conference Publication

Reliability and Validity of Endoscopic Scoring in Pouchitis: Agreement Among Reviewers and Correlation with Histology

Khoo, E., Fernandes, R., Walker, N., Howlett, M., Lourie, R., Liu, J., Webb, L. and Begun, J. (2026). Reliability and Validity of Endoscopic Scoring in Pouchitis: Agreement Among Reviewers and Correlation with Histology. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/ecco-jcc/jjaf231.532

Reliability and Validity of Endoscopic Scoring in Pouchitis: Agreement Among Reviewers and Correlation with Histology

2026

Conference Publication

Prescribing patterns and persistence of advanced therapies in people with Ulcerative Colitis who are bio-experienced: Insights from the Crohn's Colitis Care (CCCare) registry

Wu, R., Ghali, M., Wilson, W., Caquilpan, , Rivas, C., Lynch, K., Haifer, C., Walker, G., Radford-Smith, G. L., Lawrance, I. C., Begun, J., Wark, G., Verdon, C., Andrews, J. M., Ghaly, S. and Connor, S. J. (2026). Prescribing patterns and persistence of advanced therapies in people with Ulcerative Colitis who are bio-experienced: Insights from the Crohn's Colitis Care (CCCare) registry. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/ecco-jcc/jjaf231.804

Prescribing patterns and persistence of advanced therapies in people with Ulcerative Colitis who are bio-experienced: Insights from the Crohn's Colitis Care (CCCare) registry

2026

Journal Article

Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UC

Li Wai Suen, Christopher F.D., Choy, Matthew C., Con, Danny, Cheng, Kaylene, Nigro, Julie, Breheney, Kerry, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson., Begun, Jakob, Radford-Smith, Graham L., Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W. ... De Cruz, Peter (2026). Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UC. Gastroenterology, 170 (1), 118-131. doi: 10.1053/j.gastro.2025.07.020

Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UC

2026

Conference Publication

Prescribing Patterns and Persistence of Advanced Therapies in people with Crohn's disease with prior advanced therapy: Crohn's Colitis Cure Data Insights Program

Ghali, M., Wu, R., Haifer, C., Lynch, K., Ng, W. S., Begun, J., Lawrance, I. C., Radford-Smith, G. L., Walker, G., Shahzad, A., Boyapati, R. K., Rivas, C., Caquilpan, , Wilson, W., Connor, S. J., Andrews, J. M. and Ghaly, S. (2026). Prescribing Patterns and Persistence of Advanced Therapies in people with Crohn's disease with prior advanced therapy: Crohn's Colitis Cure Data Insights Program. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/ecco-jcc/jjaf231.814

Prescribing Patterns and Persistence of Advanced Therapies in people with Crohn's disease with prior advanced therapy: Crohn's Colitis Cure Data Insights Program

2026

Conference Publication

Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists

Chen, L., Ruddick-Collins, L., An, Y. K., Baraty, B., Begun, J., Boyapati, R. K., Bryant, R., Smith, R. and Srinivasan, A. (2026). Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/ecco-jcc/jjaf231.587

Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists

2025

Journal Article

Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction

Fernandes, Richard Gareth, Khoo, Emi, Jensen Harris, Heidi, Gilmore, Robert, Khaing, Myat Myat, Ennever, Jenny, Mullen, Kaity, Begun, Jakob and An, Yoon-Kyo (2025). Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction. Journal of Crohn's and Colitis, 19 (12) jjaf221. doi: 10.1093/ecco-jcc/jjaf221

Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction

2025

Journal Article

Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium

An, Yoon‐Kyo, Lindsay, Niamh, Allan, Natalie, Khoo, Emi, Fernandes, Richard, Gilmore, Robert, Amiss, Anna, Pham, Hai, Ooi, Soong‐Yuan, Thin, Lena, Lightowler, Daniel, Connor, Susan J., Williams, Astrid, De Cruz, Peter, Li Wai Suen, Christopher F. D., Kariyawasam, Viraj, Mitrev, Nikola, Ghaly, Simon, Andrews, Jane M., Christensen, Britt, Sparrow, Miles P., White, Lauren S., Bryant, Robert, Ding, Nik S., Leong, Rupert W., Van Langenberg, Daniel R., Seltenreich, Hansjoerg, Subramaniam, Kavitha, Radford‐Smith, Graham and Begun, Jakob (2025). Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium. JGH Open, 9 (12) e70322, e70322. doi: 10.1002/jgh3.70322

Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium

2025

Journal Article

Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort

Wu, Rodger, Rivas, Consuelo, Su, Wai Kin, Deschenes, Renée, Wilson, William, Pipicella, Joseph L., Connor, Susan J., Andrews, Jane M., An, Yoon-Kyo, Begun, Jakob, Boyapati, Ray, Dutt, Shoma, Gearry, Richard B, Ghaly, Simon, Haifer, Craig, Lawrance, Ian C, Lynch, Kate, Moore, Gregory, Radford-Smith, Graham, Shahzad, Asif, Schultz, Michael, Su, Heidi, Ng, Watson, Verdon, Christine, Walker, Gareth and Wark, Gabrielle (2025). Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort. JGH Open, 9 (12) e70308, 1-14. doi: 10.1002/jgh3.70308

Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort

2025

Conference Publication

Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages

Bisht, Kavita, Zhong, Ruiqing, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Tang, Yifu, Giri, Rabina, Amiss, Anna, Alexander, Kylie, Millard, Susan, Pettit, Allison, Winkler, Ingrid, Begun, Jakob and Levesque, Jean-Pierre (2025). Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages. 54th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Kumamoto, Japan, 24-27 September 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2025.105131

Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages

2025

Journal Article

Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia

Fernandes, Richard Gareth, Kim, Dong Hyun, Ruddick-Collins, Leonie, Vasudevan, Abhinav, Brownson, Anthony Robert, Ngoi, Benjamin, Lin, Chun-Chi, Haifer, Craig, Kim, Dae Sung, Swe, Ei, Wright, Emily Kate, Song, Eun Mi, Mahy, Gillian, Moore, Gregory Thomas, Lee, Hyun Seok, Kim, Hyun Soo, Zhang, Jennifer, Yan Mak, Joyce Wing, Lee, Jun, Lynch, Kate, Gazelakis, Kathryn, Rice, Katie, Kim, Kyeong Ok, Liu, Jing, Lilian Bracken, Lucy Mary, Garg, Mayur, Schultz, Michael, Clark, Nicholas, Cao, Qian ... An, Yoon-Kyo (2025). Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2025.10.019

Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia

2025

Journal Article

Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations

Tan, Wei-Lian, Khoo, Emi, Khaing, Myat-Myat, Barr, Emily, Fernandes, Richard G., Pham, Hai, An, Yoon-Kyo and Begun, Jakob (2025). Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations. Journal of Gastroenterology and Hepatology, 40 (10), 2472-2481. doi: 10.1111/jgh.70019

Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations

2025

Journal Article

Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy

Cai, Benjamin, Giri, Rabina, Cameron, Amy J., Rahman, M. Arifur, Small, Annabelle, Altmann, Christopher, Lim, Yenkai, Rehaume, Linda M., Morrison, Mark, Wechalekar, Mihir D., Begun, Jakob, Bergot, Anne-Sophie and Thomas, Ranjeny (2025). Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy. JCI Insight, 10 (17) e188028, 1-19. doi: 10.1172/jci.insight.188028

Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy

2025

Conference Publication

Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease

Yeo, Jeremy, Gilmore, Robert, Pham, Lily, Fernandes, Richard, Nguyen, Andrew, Vasudevan, Abhinav, Parkash, Nikita, Moore, Gregory, Christmas, Michael, White, Lauren, Subhaharan, Deloshaan, Mohsen, Waled, Ramaswamy, Pradeep Kakkadasam, Massouridis, Benjamin, Sparrow, Miles P., Ding, John, Lin, Alan, Clark, Nicholas, An, Yoon and Begun, Jakob (2025). Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease. HOBOKEN: WILEY.

Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease