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2026

Journal Article

Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists

Chen, Lynna, Ruddick-Collins, Leonie, An, Yoon-Kyo, Baraty, Brandon, Begun, Jakob, Boyapati, Ray K., Bryant, Robert V., Smith, Rebecca L. and Srinivasan, Ashish R. (2026). Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists. Therapeutic Advances in Gastroenterology, 19 17562848261432538. doi: 10.1177/17562848261432538

Examining attitudes to intestinal ultrasound in inflammatory bowel disease: a national survey of Australian gastroenterologists

2026

Journal Article

Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus

Lu, Lantian, Cruz, Jazmina L. Gonzalez, Giri, Rabina, Zhang, Yuexiao, Bashiri, Sahra, Cadena, Leslie C. Domínguez, Li, Shuhang, Khalil, Zeinab G., Hussein, Waleed M., Wang, Jingwen, Kiong, Jolynn, Lu, Xuehan, Zhang, Jiahui, Lu, Miao, Huang, Wenbin, Kong, Wei Yang, Nahar, Ummey Jannatun, Koirala, Prashamsa, Guo, Zhong, Walden, Patricia, Blumenthal, Antje, Begun, Jakob, Alexandrov, Kirill, Toth, Istvan, Stephenson, Rachel J. and Skwarczynski, Mariusz (2026). Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus. Small e11459. doi: 10.1002/smll.202511459

Development of a novel polyleucine-based immunopotentiator for subunit vaccines against Group A Streptococcus

2026

Conference Publication

DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS

Horgan, Kevin, Barnett, Jacqueline, Godovannyi, Artem, Usakiewicz, Jacek, Adur, Malavika, Mayer, Emeran, Begun, Jakob and Gibson, Deanna (2026). DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS. Crohn's and Colitis Congress, Las Vegas Nv, Jan 22-24, 2026. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.

DEVELOPMENT OF A NEXT GENERATION ENGINEERED LIVE MICROBIOME BIOTHERAPEUTIC, E COLI NISSLE 1917-TTR, FOR ULCERATIVE COLITIS

2026

Journal Article

Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction

Giri, Rabina, Lee, Minyi, Magor, Graham, Bergot, Anne-Sophie, He, Yaowu, Kryza, Thomas, Khan, Tashbib, Schreiber, Veronika, Gordon, Robert J., Zagani, Rachid, Hasnain, Sumaira Z., Lourie, Rohan, Ewing, Adam, Hooper, John D., Thomas, Ranjeny, Florin, Timothy H., Perkins, Andrew, Gala, Manish and Begun, Jakob (2026). Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction. Cellular and Molecular Gastroenterology and Hepatology, 20 (2) 101659, 1-20. doi: 10.1016/j.jcmgh.2025.101659

Pathogenic OTUD3 mutations predispose to ulcerative colitis due to barrier dysfunction

2025

Journal Article

Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction

Fernandes, Richard Gareth, Khoo, Emi, Jensen Harris, Heidi, Gilmore, Robert, Khaing, Myat Myat, Ennever, Jenny, Mullen, Kaity, Begun, Jakob and An, Yoon-Kyo (2025). Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction. Journal of Crohn's and Colitis, 19 (12) jjaf221. doi: 10.1093/ecco-jcc/jjaf221

Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction

2025

Journal Article

Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium

An, Yoon‐Kyo, Lindsay, Niamh, Allan, Natalie, Khoo, Emi, Fernandes, Richard, Gilmore, Robert, Amiss, Anna, Pham, Hai, Ooi, Soong‐Yuan, Thin, Lena, Lightowler, Daniel, Connor, Susan J., Williams, Astrid, De Cruz, Peter, Li Wai Suen, Christopher F. D., Kariyawasam, Viraj, Mitrev, Nikola, Ghaly, Simon, Andrews, Jane M., Christensen, Britt, Sparrow, Miles P., White, Lauren S., Bryant, Robert, Ding, Nik S., Leong, Rupert W., Van Langenberg, Daniel R., Seltenreich, Hansjoerg, Subramaniam, Kavitha, Radford‐Smith, Graham and Begun, Jakob (2025). Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium. JGH Open, 9 (12) e70322, e70322. doi: 10.1002/jgh3.70322

Australian real‐world effectiveness and safety of ustekinumab for the treatment of Crohn's Disease: Results of the AURORA Study, including the ANZIBD Consortium

2025

Journal Article

Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort

Wu, Rodger, Rivas, Consuelo, Su, Wai Kin, Deschenes, Renée, Wilson, William, Pipicella, Joseph L., Connor, Susan J., Andrews, Jane M., An, Yoon-Kyo, Begun, Jakob, Boyapati, Ray, Dutt, Shoma, Gearry, Richard B, Ghaly, Simon, Haifer, Craig, Lawrance, Ian C, Lynch, Kate, Moore, Gregory, Radford-Smith, Graham, Shahzad, Asif, Schultz, Michael, Su, Heidi, Ng, Watson, Verdon, Christine, Walker, Gareth and Wark, Gabrielle (2025). Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort. JGH Open, 9 (12) e70308, 1-14. doi: 10.1002/jgh3.70308

Patterns and predictors of steroid use in a real-world inflammatory bowel disease cohort

2025

Conference Publication

Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages

Bisht, Kavita, Zhong, Ruiqing, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Tang, Yifu, Giri, Rabina, Amiss, Anna, Alexander, Kylie, Millard, Susan, Pettit, Allison, Winkler, Ingrid, Begun, Jakob and Levesque, Jean-Pierre (2025). Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages. 54th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Kumamoto, Japan, 24-27 September 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2025.105131

Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages

2025

Journal Article

Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia

Fernandes, Richard Gareth, Kim, Dong Hyun, Ruddick-Collins, Leonie, Vasudevan, Abhinav, Brownson, Anthony Robert, Ngoi, Benjamin, Lin, Chun-Chi, Haifer, Craig, Kim, Dae Sung, Swe, Ei, Wright, Emily Kate, Song, Eun Mi, Mahy, Gillian, Moore, Gregory Thomas, Lee, Hyun Seok, Kim, Hyun Soo, Zhang, Jennifer, Yan Mak, Joyce Wing, Lee, Jun, Lynch, Kate, Gazelakis, Kathryn, Rice, Katie, Kim, Kyeong Ok, Liu, Jing, Lilian Bracken, Lucy Mary, Garg, Mayur, Schultz, Michael, Clark, Nicholas, Cao, Qian ... An, Yoon-Kyo (2025). Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2025.10.019

Acute severe ulcerative colitis patients from Asia have lower colectomy risk than patients from Australasia

2025

Journal Article

Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations

Tan, Wei-Lian, Khoo, Emi, Khaing, Myat-Myat, Barr, Emily, Fernandes, Richard G., Pham, Hai, An, Yoon-Kyo and Begun, Jakob (2025). Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations. Journal of Gastroenterology and Hepatology, 40 (10), 2472-2481. doi: 10.1111/jgh.70019

Point-of-care intestinal ultrasound impacts inflammatory bowel disease care and reduces the need for additional investigations

2025

Journal Article

Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy

Cai, Benjamin, Giri, Rabina, Cameron, Amy J., Rahman, M. Arifur, Small, Annabelle, Altmann, Christopher, Lim, Yenkai, Rehaume, Linda M., Morrison, Mark, Wechalekar, Mihir D., Begun, Jakob, Bergot, Anne-Sophie and Thomas, Ranjeny (2025). Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy. JCI Insight, 10 (17) e188028, 1-19. doi: 10.1172/jci.insight.188028

Pro-inflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy

2025

Conference Publication

Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assay

Krause, Lutz, Boyd, Joel, Cooper, Martha, Pribyl, Alena, An, Yoon-Kyo, Begun, Jakob and Cuive, Paraic O. (2025). Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assay. HOBOKEN: WILEY.

Inflammatory bowel disease flares are associated with elevated pathogen prevalence as identified via the MetaPanel metagenomic diagnostic assay

2025

Journal Article

IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, Australia

Mahadevan, Uma, Jairath, Vipul, Begun, Jakob, Pudipeddi, Aviv, Garg, Mayur, De Cruz, Peter, Li Wai Suen, Christopher F. D., Choy, Matthew C., Con, Danny, Vaughan, Rose, Chetwood, John D., Clark, David A., Haifer, Craig, Sparrow, Miles P., Leong, Rupert and Mountifield, Réme (2025). IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, Australia. Journal of Gastroenterology and Hepatology, 40 (S3), 3-22. doi: 10.1111/jgh.70020

IBD 2024: charting a new course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, Australia

2025

Conference Publication

The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patients

Huynh, David, Khoo, Emi, Anandan, Aathavan Shanmuga and Begun, Jakob (2025). The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patients. HOBOKEN: WILEY.

The burden of viral respiratory infections in immunosuppressed inflammatory bowel disease patients

2025

Conference Publication

Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UC

Suen, Christopher F. D. Li Wai, Choy, Matthew C., Con, Danny, Driver, Kate, Bruen, Dylan, Glason, Joshua, Bonelli, Fabrizio, Bittar, Intissar, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham, Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S. ... De Cruz, Peter (2025). Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UC. HOBOKEN: WILEY.

Early faecal calprotectin predicts clinical outcomes in acute severe ulcerative colitis: Results from PREDICT-UC

2025

Conference Publication

Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activity

Khaing, Myat Myat, Fernandes, Richard, An, Yoon-Kyo, Baraty, Brandon, Bryant, Robert V., Ghaly, Simon, Smith, Rebecca, Srinivasan, Ashish, Hay, Karen and Begun, Jakob (2025). Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activity. HOBOKEN: WILEY.

Comparative accuracy and reliability of handheld versus cart-based ultrasound in assessing inflammatory bowel disease activity

2025

Conference Publication

Early serum and faecal infliximab levels predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from the PREDICT-UC randomised controlled trial

Suen, Christopher F. D. Li Wai, Choy, Matthew C., Con, Danny, Cheng, Kaylene, Nigro, Julie, Breheney, Kerry, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William, Wright, Emily K., Taylor, Kirstin, Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham L., Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W. ... De Cruz, Peter (2025). Early serum and faecal infliximab levels predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from the PREDICT-UC randomised controlled trial. HOBOKEN: WILEY.

Early serum and faecal infliximab levels predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from the PREDICT-UC randomised controlled trial

2025

Conference Publication

Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease

Yeo, Jeremy, Gilmore, Robert, Pham, Lily, Fernandes, Richard, Nguyen, Andrew, Vasudevan, Abhinav, Parkash, Nikita, Moore, Gregory, Christmas, Michael, White, Lauren, Subhaharan, Deloshaan, Mohsen, Waled, Ramaswamy, Pradeep Kakkadasam, Massouridis, Benjamin, Sparrow, Miles P., Ding, John, Lin, Alan, Clark, Nicholas, An, Yoon and Begun, Jakob (2025). Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease. HOBOKEN: WILEY.

Australian multicentre real-world experience of upadacitinib induction therapy for moderate to severe Crohn's disease

2025

Conference Publication

Complete disease clearance as a novel composite endpoint to predict long-term relapse in vedolizumab-treated patients with ulcerative colitis: A post-hoc analysis from the VIEWS randomised controlled trial

Pudipeddi, Aviv, Paramsothy, Sudarshan, Kariyawasam, Viraj, Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon-Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark G., De Cruz, Peter, Fung, Caroline, Redmond, Diane, Chan, Webber, Mourad, Fadi, Kermeen, Melissa and Leong, Rupert W. (2025). Complete disease clearance as a novel composite endpoint to predict long-term relapse in vedolizumab-treated patients with ulcerative colitis: A post-hoc analysis from the VIEWS randomised controlled trial. HOBOKEN: WILEY.

Complete disease clearance as a novel composite endpoint to predict long-term relapse in vedolizumab-treated patients with ulcerative colitis: A post-hoc analysis from the VIEWS randomised controlled trial

2025

Journal Article

Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study

Gilmore, Robert, Fernandes, Richard, Hartley, Imogen, Arzivian, Arteen, Leong, Rupert, Andrew, Bridgette, Vasudevan, Abhinav, Greeve, Tessa, Moore, Gregory Thomas, Kim, Steven, Lightowler, Daniel, Singh, Abhey, Mahy, Gillian, Mithanthaya, Aditya, Venugopaul, Kannan, Han, Sangwoo, Bryant, Robert, West, Jack, Segal, Jonathan, Christensen, Britt, Corte, Crispin, Ding, Nik, An, Yoon-Kyo and Begun, Jakob (2025). Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study. Intestinal Research, 23 (3), 347-357. doi: 10.5217/ir.2024.00127

Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study