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2025

Conference Publication

Correlation of biochemical, endoscopic and histologic endpoints in vedolizumab-treated patients with ulcerative colitis: a post-hoc analysis from the VIEWS randomised controlled trial

Pudipeddi, A., Dhanji, P., Paramsothy, S., Kariyawasam, V., Paramsothy, R., Ghaly, S., Haifer, C., An, Y. K., Begun, J., Connor, S., Corte, C., Ward, M., De Cruz, P., Fung, C., Redmond, D., Chan, W., Mourad, F., Kermeen, M. and Leong, R. (2025). Correlation of biochemical, endoscopic and histologic endpoints in vedolizumab-treated patients with ulcerative colitis: a post-hoc analysis from the VIEWS randomised controlled trial. 20th Congress of ECCO, Berlin, Germany, 19-22 February 2025. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjae190.0431

Correlation of biochemical, endoscopic and histologic endpoints in vedolizumab-treated patients with ulcerative colitis: a post-hoc analysis from the VIEWS randomised controlled trial

2025

Journal Article

Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis: a case report

Huynh, David, Khaing, Myat Myat, Fernandes, Richard Gareth, Malloy, Reuben, Lin, Lei, Gilmore, Robert, Walker, Nicole, Khoo, Emi and Begun, Jakob (2025). Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis: a case report. Case Reports in Gastroenterology, 19 (1), 1-6. doi: 10.1159/000542711

Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis: a case report

2025

Journal Article

Epidemiology and treatment patterns of fistulizing Crohn's disease in a large, real-world Australasian cohort

McNamara, Jack, Wilson, William, Pipicella, Joseph L., Ghaly, Simon, Begun, Jakob, Lawrance, Ian C., Gearry, Richard, Andrews, Jane M. and Connor, Susan J. (2025). Epidemiology and treatment patterns of fistulizing Crohn's disease in a large, real-world Australasian cohort. Gastro Hep Advances, 4 (4) 100594, 100594. doi: 10.1016/j.gastha.2024.100594

Epidemiology and treatment patterns of fistulizing Crohn's disease in a large, real-world Australasian cohort

2025

Journal Article

Editorial: Intestinal Ultrasound for the Assessment of Constipation—Out of the Shadows? Authors' Reply

Mathias, Ryan M., Goodsall, Thomas M., Parker, Claire E., Day, Alice S., An, Yoon K., Baraty, Brandon, Basnayake, Chamara, Begun, Jakob, Boyapati, Ray K., Burgell, Rebecca, Dolinger, Michael T., Maconi, Giovanni, Novak, Kerri L., Sagami, Shintaro, Smith, Rebecca L., Srinivasan, Ashish R., Taylor, Stuart A., Jairath, Vipul, Ma, Christopher and Bryant, Robert V. (2025). Editorial: Intestinal Ultrasound for the Assessment of Constipation—Out of the Shadows? Authors' Reply. Alimentary Pharmacology and Therapeutics, 62 (8), 855-856. doi: 10.1111/apt.70338

Editorial: Intestinal Ultrasound for the Assessment of Constipation—Out of the Shadows? Authors' Reply

2025

Conference Publication

Janus Kinase Inhibitors for the Management of Acute Severe Ulcerative Colitis: A Multicentre Study

Gilmore, R., Fernandes, R., Chin, S., Con, D., De Cruz, P., Demase, K., Sparrow, M., Thin, L., Baker, J., Venugopal, K., Lucas, S., Garg, M., Loebenstein, M., Nguyen, A., Moore, G., Tandon, B., Bryant, R., MacFarlane, K., Lynch, K., Abdul, S., Subhaharan, D., Mohsen, W., Haig, A., Day, M., White, L., Begun, J. and An, Y. K. (2025). Janus Kinase Inhibitors for the Management of Acute Severe Ulcerative Colitis: A Multicentre Study. 20th Congress of ECCO, Berlin, Germany, 19-22 February 2025. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjae190.1203

Janus Kinase Inhibitors for the Management of Acute Severe Ulcerative Colitis: A Multicentre Study

2024

Journal Article

Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies

Rubin, David T., Allegretti, Jessica R, Panés, Julián, Shipitofsky, Nicole, Yarandi, Shadi S, Huang, Kuan-Hsiang Gary, Germinaro, Matthew, Wilson, Rebbecca, Zhang, Hongyan, Johanns, Jewel, Feagan, Brian G, Hisamatsu, Tadakazu, Lichtenstein, Gary R, Bressler, Brian, Peyrin-Biroulet, Laurent, Sands, Bruce E, Dignass, Axel, Abrahamovych, Orest, Abu-Farsakh, Niazy, Afanasieva, Halyna, Akpinar, Hale, Kharrat, Houssam Al, Altintas, Engin, Altwegg, Romain, Andreev, Pavel, Aomatsu, Kazuki, Araki, Hiroshi, Argollo, Marjorie, Ariel, Federico ... Zureikat, Firas (2024). Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies. The Lancet, 405 (10472), 33-49. doi: 10.1016/S0140-6736(24)01927-5

Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies

2024

Journal Article

Does improving depression symptoms in young adults with inflammatory bowel disease alter their microbiome?

Davies, Julie M., Teh, Jing Jie, Ewais, Tatjana and Begun, Jakob (2024). Does improving depression symptoms in young adults with inflammatory bowel disease alter their microbiome?. Inflammatory Bowel Diseases, 30 (12), 2428-2439. doi: 10.1093/ibd/izae121

Does improving depression symptoms in young adults with inflammatory bowel disease alter their microbiome?

2024

Conference Publication

Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia

Bisht, Kavita, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Giri, Rabina, Amiss, Anna, Tang, Yifu, Alexander, Kylie, Millard, Susan, Winkler, Ingrid G., Pettit, Allison, Begun, Jakob and Levesque, Jean-Pierre (2024). Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-193349

Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia

2024

Journal Article

Effects of thiopurine withdrawal on vedolizumab-treated patients with ulcerative colitis: a randomized controlled trial

Pudipeddi, Aviv, Paramsothy, Sudarshan, Kariyawasam, Viraj, Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon-Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark G., De Cruz, Peter, Fung, Caroline Lan-San, Redmond, Diane, Chan, Webber, Mourad, Fadi, Kermeen, Melissa and Leong, Rupert W. (2024). Effects of thiopurine withdrawal on vedolizumab-treated patients with ulcerative colitis: a randomized controlled trial. Clinical Gastroenterology and Hepatology, 22 (11), 2299-2308. doi: 10.1016/j.cgh.2024.04.019

Effects of thiopurine withdrawal on vedolizumab-treated patients with ulcerative colitis: a randomized controlled trial

2024

Journal Article

Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial

Choy, Matthew C., Li Wai Suen, Christopher F. D., Con, Danny, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William R., Wright, Emily K., Taylor, Kirstin M., Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham, Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W., Sparrow, Miles P. and De Cruz, Peter (2024). Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial. The Lancet Gastroenterology & Hepatology, 9 (11), 981-996. doi: 10.1016/s2468-1253(24)00200-0

Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial

2024

Journal Article

Defining mucosal healing in randomized controlled trials of inflammatory bowel disease: a systematic review and future perspective

Parigi, Tommaso Lorenzo, Solitano, Virginia, Armuzzi, Alessandro, Acosta, Manuel Barreiro de, Begun, Jake, Ben-Horin, Shomron, Biedermann, Luc, Colombel, Jean-Frederic, Dignass, Axel, Fumery, Mathurin, Ghosh, Subrata, Kobayashi, Taku, Louis, Edouard, Magro, Fernando, Panaccione, Remo, Rausch, Astrid, Reinisch, Walter, Selinger, Christian, Jairath, Vipul, Danese, Silvio and Peyrin-Biroulet, Laurent (2024). Defining mucosal healing in randomized controlled trials of inflammatory bowel disease: a systematic review and future perspective. United European Gastroenterology Journal, 12 (9), 1266-1279. doi: 10.1002/ueg2.12671

Defining mucosal healing in randomized controlled trials of inflammatory bowel disease: a systematic review and future perspective

2024

Conference Publication

The Efficacy of Maintenance Treatment with Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results at Week 44 by Biologic/Janus Kinase History

Allegretti, Jessica R., Panés, Julián, Peyrin-Biroulet, Laurent, Sands, Bruce E., Yarandi, Shadi, Huang, Kuan-Hsiang G., Germinaro, Matthew, Zhan, Jia, Zhang, Hongyan, Begun, Jakob, Kierkuś, Jarosław, Kravchenko, Tetiana, Hisamatsu, Tadakazu, Rubin, David T., Bressler, Brian and Dignass, Axel (2024). The Efficacy of Maintenance Treatment with Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results at Week 44 by Biologic/Janus Kinase History. 2024 ACG Annual Meeting, Philadelphia, PA United States, 25-30 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.14309/01.ajg.0001034328.68326.43

The Efficacy of Maintenance Treatment with Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results at Week 44 by Biologic/Janus Kinase History

2024

Journal Article

International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement

Lu, Cathy, Rosentreter, Ryan, Parker, Claire E., Remillard, Julie, Wilson, Stephanie R., Baker, Mark E., Bhatnagar, Gauraang, Begun, Jakob, Bruining, David H., Bryant, Robert V., Christensen, Britt, Feagan, Brian G., Fletcher, Joel G., Gordon, Ilyssa, Henderson, Gaylyn, Jairath, Vipul, Knudsen, John, Kucharzik, Torsten, Lesack, Kyle, Maaser, Christian, Maconi, Giovanni, Novak, Kerri, Rimola, Jordi, Taylor, Stuart A., Wilkens, Rune, Rieder, Florian and on behalf of the Stenosis Therapy and Anti-Fibrotic Research (STAR) consortium (2024). International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement. The Lancet Gastroenterology & Hepatology, 9 (12), 1101-1110. doi: 10.1016/s2468-1253(24)00265-6

International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement

2024

Journal Article

Group B Streptococcus vaginal colonisation throughout pregnancy is associated with decreased Lactobacillus crispatus and increased Lactobacillus iners abundance in the vaginal microbial community

Maidment, Toby I., Pelzer, Elise S., Borg, Danielle J., Cheung, Eddie, Begun, Jake, Nitert, Marloes Dekker, Rae, Kym M., Clifton, Vicki L. and Carey, Alison J. (2024). Group B Streptococcus vaginal colonisation throughout pregnancy is associated with decreased Lactobacillus crispatus and increased Lactobacillus iners abundance in the vaginal microbial community. Frontiers in Cellular and Infection Microbiology, 14 1435745, 1-11. doi: 10.3389/fcimb.2024.1435745

Group B Streptococcus vaginal colonisation throughout pregnancy is associated with decreased Lactobacillus crispatus and increased Lactobacillus iners abundance in the vaginal microbial community

2024

Conference Publication

Healthcare utilisation in people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program

Su, Wai Kin, Pipicella, Joseph, Wilson, William, Kim, Andrew, Davidson, Chloe, Giles, Edward, Walker, Gareth, Forbes, Angela, Su, Heidi, Lawrance, Ian, Dutt, Shoma, Lynch, Kate, Brett, Laurel, Begun, Jakob, Connor, Susan J. and Andrews, Jane (2024). Healthcare utilisation in people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.

Healthcare utilisation in people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program

2024

Conference Publication

The prevalence and impact of obesity in an ANZ cohort of people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program

Kaazan, Patricia, Su, Wai Kin, Rayner, Christopher, Walker, Gareth, Wilson, William, Dinoy, Elaine, Wark, Gabrielle, Forbes, Angela, Schultz, Michael, Yap, Jia, Lawrance, Ian, Dutt, Shoma, Lynch, Kate, Brett, Laurel, Begun, Jakob, Andrews, Jane and Connor, Susan J. (2024). The prevalence and impact of obesity in an ANZ cohort of people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.

The prevalence and impact of obesity in an ANZ cohort of people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program

2024

Conference Publication

Mortality in inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program

Alsulaibi, Owen, Su, Wai Kin, Wilson, William, Sin, Hiu Ching Letisia, Ng, Watson, Walker, Gareth, Forbes, Angela, Lawrance, Ian, Lynch, Kate, Begun, Jakob, Connor, Susan J. and Andrews, Jane (2024). Mortality in inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.

Mortality in inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program

2024

Conference Publication

Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis

Huynh, David, Khaing, Myat, Fernandes, Richard, Malloy, Reuben, Lin, Lei, Gilmore, Robert, Walker, Nicole, Khoo, Emi and Begun, Jakob (2024). Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2022, Sydney, NSW Australia, 9 - 11 September 2022. Richmond, VIC Australia: John Wiley & Sons. doi: 10.1111/jgh.16702

Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis

2024

Conference Publication

Topical upadacitinib is effective in distal ulcerative colitis: A case study and pre-clinical proof of concept

Giri, Rabina, Amiss, Anna, Riches, Bruce, Carpinelli De Jesus, Matheus and Begun, Jakob (2024). Topical upadacitinib is effective in distal ulcerative colitis: A case study and pre-clinical proof of concept. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.

Topical upadacitinib is effective in distal ulcerative colitis: A case study and pre-clinical proof of concept

2024

Conference Publication

The psycho-social impact of fistulising perianal Crohn's disease in Australasia: Crohn's Colitis Cure (CCC) data insights program

Nano, Dominique, Su, Wai Kin, Mcnamara, Jack, Wilson, William, Arzivian, Arteen, Williams, Astrid-Jane, Walker, Gareth, Forbes, Angela, Su, Heidi, Giles, Edward, Lawrance, Ian, Dutt, Shoma, Lynch, Kate, Brett, Laurel, Begun, Jakob, Andrews, Jane and Connor, Susan J. (2024). The psycho-social impact of fistulising perianal Crohn's disease in Australasia: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.

The psycho-social impact of fistulising perianal Crohn's disease in Australasia: Crohn's Colitis Cure (CCC) data insights program