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2024 Journal Article Effects of thiopurine withdrawal on vedolizumab-treated patients with ulcerative colitis: a randomized controlled trialPudipeddi, Aviv, Paramsothy, Sudarshan, Kariyawasam, Viraj, Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon-Kyo, Begun, Jakob, Connor, Susan J., Corte, Crispin, Ward, Mark G., De Cruz, Peter, Fung, Caroline Lan-San, Redmond, Diane, Chan, Webber, Mourad, Fadi, Kermeen, Melissa and Leong, Rupert W. (2024). Effects of thiopurine withdrawal on vedolizumab-treated patients with ulcerative colitis: a randomized controlled trial. Clinical Gastroenterology and Hepatology, 22 (11), 2299-2308. doi: 10.1016/j.cgh.2024.04.019 |
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2024 Journal Article Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trialChoy, Matthew C., Li Wai Suen, Christopher F. D., Con, Danny, Boyd, Kristy, Pena, Raquel, Burrell, Kathryn, Rosella, Ourania, Proud, David, Brouwer, Richard, Gorelik, Alexandra, Liew, Danny, Connell, William R., Wright, Emily K., Taylor, Kirstin M., Pudipeddi, Aviv, Sawers, Michelle, Christensen, Britt, Ng, Watson, Begun, Jakob, Radford-Smith, Graham, Garg, Mayur, Martin, Neal, van Langenberg, Daniel R., Ding, Nik S., Beswick, Lauren, Leong, Rupert W., Sparrow, Miles P. and De Cruz, Peter (2024). Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial. The Lancet Gastroenterology & Hepatology, 9 (11), 981-996. doi: 10.1016/s2468-1253(24)00200-0 |
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2024 Journal Article Defining mucosal healing in randomized controlled trials of inflammatory bowel disease: a systematic review and future perspectiveParigi, Tommaso Lorenzo, Solitano, Virginia, Armuzzi, Alessandro, Acosta, Manuel Barreiro de, Begun, Jake, Ben-Horin, Shomron, Biedermann, Luc, Colombel, Jean-Frederic, Dignass, Axel, Fumery, Mathurin, Ghosh, Subrata, Kobayashi, Taku, Louis, Edouard, Magro, Fernando, Panaccione, Remo, Rausch, Astrid, Reinisch, Walter, Selinger, Christian, Jairath, Vipul, Danese, Silvio and Peyrin-Biroulet, Laurent (2024). Defining mucosal healing in randomized controlled trials of inflammatory bowel disease: a systematic review and future perspective. United European Gastroenterology Journal, 12 (9), 1266-1279. doi: 10.1002/ueg2.12671 |
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2024 Conference Publication The Efficacy of Maintenance Treatment with Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results at Week 44 by Biologic/Janus Kinase HistoryAllegretti, Jessica R., Panés, Julián, Peyrin-Biroulet, Laurent, Sands, Bruce E., Yarandi, Shadi, Huang, Kuan-Hsiang G., Germinaro, Matthew, Zhan, Jia, Zhang, Hongyan, Begun, Jakob, Kierkuś, Jarosław, Kravchenko, Tetiana, Hisamatsu, Tadakazu, Rubin, David T., Bressler, Brian and Dignass, Axel (2024). The Efficacy of Maintenance Treatment with Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results at Week 44 by Biologic/Janus Kinase History. 2024 ACG Annual Meeting, Philadelphia, PA United States, 25-30 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.14309/01.ajg.0001034328.68326.43 |
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2024 Journal Article International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statementLu, Cathy, Rosentreter, Ryan, Parker, Claire E., Remillard, Julie, Wilson, Stephanie R., Baker, Mark E., Bhatnagar, Gauraang, Begun, Jakob, Bruining, David H., Bryant, Robert V., Christensen, Britt, Feagan, Brian G., Fletcher, Joel G., Gordon, Ilyssa, Henderson, Gaylyn, Jairath, Vipul, Knudsen, John, Kucharzik, Torsten, Lesack, Kyle, Maaser, Christian, Maconi, Giovanni, Novak, Kerri, Rimola, Jordi, Taylor, Stuart A., Wilkens, Rune, Rieder, Florian and on behalf of the Stenosis Therapy and Anti-Fibrotic Research (STAR) consortium (2024). International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement. The Lancet Gastroenterology & Hepatology, 9 (12), 1101-1110. doi: 10.1016/s2468-1253(24)00265-6 |
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2024 Journal Article Group B Streptococcus vaginal colonisation throughout pregnancy is associated with decreased Lactobacillus crispatus and increased Lactobacillus iners abundance in the vaginal microbial communityMaidment, Toby I., Pelzer, Elise S., Borg, Danielle J., Cheung, Eddie, Begun, Jake, Nitert, Marloes Dekker, Rae, Kym M., Clifton, Vicki L. and Carey, Alison J. (2024). Group B Streptococcus vaginal colonisation throughout pregnancy is associated with decreased Lactobacillus crispatus and increased Lactobacillus iners abundance in the vaginal microbial community. Frontiers in Cellular and Infection Microbiology, 14 1435745, 1-11. doi: 10.3389/fcimb.2024.1435745 |
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2024 Conference Publication Healthcare utilisation in people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights programSu, Wai Kin, Pipicella, Joseph, Wilson, William, Kim, Andrew, Davidson, Chloe, Giles, Edward, Walker, Gareth, Forbes, Angela, Su, Heidi, Lawrance, Ian, Dutt, Shoma, Lynch, Kate, Brett, Laurel, Begun, Jakob, Connor, Susan J. and Andrews, Jane (2024). Healthcare utilisation in people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication The prevalence and impact of obesity in an ANZ cohort of people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights programKaazan, Patricia, Su, Wai Kin, Rayner, Christopher, Walker, Gareth, Wilson, William, Dinoy, Elaine, Wark, Gabrielle, Forbes, Angela, Schultz, Michael, Yap, Jia, Lawrance, Ian, Dutt, Shoma, Lynch, Kate, Brett, Laurel, Begun, Jakob, Andrews, Jane and Connor, Susan J. (2024). The prevalence and impact of obesity in an ANZ cohort of people with inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication Mortality in inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights programAlsulaibi, Owen, Su, Wai Kin, Wilson, William, Sin, Hiu Ching Letisia, Ng, Watson, Walker, Gareth, Forbes, Angela, Lawrance, Ian, Lynch, Kate, Begun, Jakob, Connor, Susan J. and Andrews, Jane (2024). Mortality in inflammatory bowel disease: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitisHuynh, David, Khaing, Myat, Fernandes, Richard, Malloy, Reuben, Lin, Lei, Gilmore, Robert, Walker, Nicole, Khoo, Emi and Begun, Jakob (2024). Upadacitinib was administered as a sequential salvage therapy for acute severe ulcerative colitis. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2022, Sydney, NSW Australia, 9 - 11 September 2022. Richmond, VIC Australia: John Wiley & Sons. doi: 10.1111/jgh.16702 |
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2024 Conference Publication Topical upadacitinib is effective in distal ulcerative colitis: A case study and pre-clinical proof of conceptGiri, Rabina, Amiss, Anna, Riches, Bruce, Carpinelli De Jesus, Matheus and Begun, Jakob (2024). Topical upadacitinib is effective in distal ulcerative colitis: A case study and pre-clinical proof of concept. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication The psycho-social impact of fistulising perianal Crohn's disease in Australasia: Crohn's Colitis Cure (CCC) data insights programNano, Dominique, Su, Wai Kin, Mcnamara, Jack, Wilson, William, Arzivian, Arteen, Williams, Astrid-Jane, Walker, Gareth, Forbes, Angela, Su, Heidi, Giles, Edward, Lawrance, Ian, Dutt, Shoma, Lynch, Kate, Brett, Laurel, Begun, Jakob, Andrews, Jane and Connor, Susan J. (2024). The psycho-social impact of fistulising perianal Crohn's disease in Australasia: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication A cross section of inflammatory bowel disease management in older persons in Australasia: Crohn's Colitis Cure (CCC) data insights programSeng, Crystal, Su, Wai Kin, Wilson, William, Haifer, Craig, Williams, Astrid-Jane, Forbes, Angela, Lawrance, Ian, Lynch, Kate, Brett, Laurel, Begun, Jakob, Connor, Susan J., Andrews, Jane and Walker, Gareth (2024). A cross section of inflammatory bowel disease management in older persons in Australasia: Crohn's Colitis Cure (CCC) data insights program. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication Efficacy of combination vedolizumab and upadacitinib treatment in refractory inflammatory bowel disease: a case seriesSwe, Ei Phyu Phyu, Gilmore, Robert, Murali, Amrutha, Etchegaray, Amirah, Fernandes, Richard, An, Yoon-Kyo and Begun, Jakob (2024). Efficacy of combination vedolizumab and upadacitinib treatment in refractory inflammatory bowel disease: a case series. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication Janus kinase inhibitors for the management of acute severe ulcerative colitis: An Australian multicentre studyGilmore, Robert, Fernandes, Richard, Subhaharan, Deloshaan, Mohsen, Waled, Thin, Lena, Chin, Simone, Con, Danny, De Cruz, Peter, Demase, Kathryn, Sparrow, Miles P., Lucas, Sarah, Garg, Mayur, Bryant, Robert, Segal, Jonathan, Christensen, Britt, Begun, Jakob and An, Yoon-Kyo (2024). Janus kinase inhibitors for the management of acute severe ulcerative colitis: An Australian multicentre study. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitisKhoo, Emi, Amiss, Anna, Lindsay, Niamh, Fernandes, Richard, Gilmore, Robert, Ding, John Nik, Connor, Susan J., Bryant, Robert, White, Lauren, Mohsen, Waled, Leong, Rupert, Ardalan, Zaid, Croft, Anthony, De Cruz, Peter, Lynch, Kate, An, Yoon-Kyo, Holtmann, Gerald and Begun, Jakob (2024). Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Conference Publication Age-dependent dysregulation of the UPR in colonic epithelium: Implications for mucosal integrityIllankoon, Thishan, Wong, Kuan Yau, Sajiir, Haressh, Mueller, Alexandra, Amiss, Anna, Begun, Jakob, Giri, Rabina, Burr, Lucy and Hasnain, Sumaira (2024). Age-dependent dysregulation of the UPR in colonic epithelium: Implications for mucosal integrity. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons. |
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2024 Journal Article Reliability of intestinal ultrasound for evaluating Crohn’s disease activity using point-of-care and central readingGoodsall, Thomas M., An, Yoon-Kyo, Andrews, Jane M., Begun, Jakob, Friedman, Antony B., Lee, Andrew, Lewindon, Peter J., Spizzo, Paul, Rodgers, Nick, Taylor, Kirstin M., White, Lauren S., Wilkens, Rune, Wright, Emily K., Zou, Lily, Maguire, Bryan R., Parker, Claire E., Rémillard, Julie, Novak, Kerri L., Panaccione, Remo, Feagan, Brian G., Jairath, Vipul, Ma, Christopher and Bryant, Robert V. (2024). Reliability of intestinal ultrasound for evaluating Crohn’s disease activity using point-of-care and central reading. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2024.08.007 |
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2024 Journal Article A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tensionGan, Wan J., Giri, Rabina, Begun, Jakob, Abud, Helen E., Hardeman, Edna C., Gunning, Peter W., Yap, Alpha S. and Noordstra, Ivar (2024). A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tension. Cytoskeleton, 82 (7), 444-455. doi: 10.1002/cm.21893 |
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2024 Journal Article Impact of a Patient Support Program on time to discontinuation of adalimumab in Australian adult patients with immunemediated inflammatory diseases-an observational studyJones, Graeme, Calao, Miriam, Begun, Jakob, Sin, Shirley, Kouhkamari, Mahsa H., Young, Elisa, Fernández-Peñas, Pablo, Watts, Alan and Östör, Andrew J. (2024). Impact of a Patient Support Program on time to discontinuation of adalimumab in Australian adult patients with immunemediated inflammatory diseases-an observational study. PLoS One, 19 (6 June) e0300624. doi: 10.1371/journal.pone.0300624 |
