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2017

Conference Publication

Endoscopic balloon dilatation has a high success rate and appears to reduce the need for surgery in patients with stricturing Crohn's disease

Lim, E., Thai, M., Hendy, P., Alchlaihawi, M., Leong, R. and Begun, J. (2017). Endoscopic balloon dilatation has a high success rate and appears to reduce the need for surgery in patients with stricturing Crohn's disease. Australian Gastroenterology Week: Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20-22 August 2017. Richmond, VIC, Australia: Wiley-Blackwell.

Endoscopic balloon dilatation has a high success rate and appears to reduce the need for surgery in patients with stricturing Crohn's disease

2017

Conference Publication

Factors influencing the need for endoscopic intervention in esophageal meat bolus impaction: a retrospective, multicenter study

Cheng, D., Lee, R., Lee, A., Begun, J. and St John, A. (2017). Factors influencing the need for endoscopic intervention in esophageal meat bolus impaction: a retrospective, multicenter study. Australian Gastroenterology Week: Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20-22 August 2017. Richmond, VIC, Australia: Wiley-Blackwell.

Factors influencing the need for endoscopic intervention in esophageal meat bolus impaction: a retrospective, multicenter study

2016

Journal Article

The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis

Elshaer, Dana and Begun, Jakob (2016). The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis. Seminars in Cell and Developmental Biology, 61, 51-59. doi: 10.1016/j.semcdb.2016.08.018

The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis

2016

Journal Article

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism

Oancea, I., Movva, R., Das, I., Aguirre de Carcer, D., Schreiber, V., Yang, Y., Purdon, A., Harrington, B., Proctor, M., Wang, R., Sheng, Y., Lobb, M., Lourie, R., Cuiv, P.O., Duley, J.A., Begun, J. and Florin, T.H.J. (2016). Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism. Gut, 66 (1), 59-69. doi: 10.1136/gutjnl-2015-310874

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism

2016

Journal Article

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuiv, Paraic O., McGuckin, Michael A. and Hasnain, Sumaira Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. Scientific Reports, 6 (1) 28990, 28990. doi: 10.1038/srep28990

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

2016

Journal Article

Genetic coding variant in GPR65 alters lysosomal pH and links lysosomal dysfunction with colitis risk

Lassen, Kara G., McKenzie, Craig I., Mari, Muriel, Murano, Tatsuro, Begun, Jakob, Baxt, Leigh A., Goel, Gautam, Villablanca, Eduardo J., Kuo, Szu-Yu, Huang, Hailiang, Macia, Laurence, Bhan, Atul K., Batten, Marcel, Daly, Mark J., Reggiori, Fulvio, Mackay, Charles R. and Xavier, Ramnik J. (2016). Genetic coding variant in GPR65 alters lysosomal pH and links lysosomal dysfunction with colitis risk. Immunity, 44 (6), 1392-1405. doi: 10.1016/j.immuni.2016.05.007

Genetic coding variant in GPR65 alters lysosomal pH and links lysosomal dysfunction with colitis risk

2016

Conference Publication

Inflammatory bowel disease in the clinic: escalation and de-escalation of therapy: a longitudinal case-based discussion

Begun, Jakob (2016). Inflammatory bowel disease in the clinic: escalation and de-escalation of therapy: a longitudinal case-based discussion. The Takeda Symposium, Sydney, NSW Australia, 13-14 February 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13348

Inflammatory bowel disease in the clinic: escalation and de-escalation of therapy: a longitudinal case-based discussion

2016

Conference Publication

Bacterial activation of thioguanine results in lymphocyte independent improvement in murine colitis

Oancea, I., Das, I., de Carcer, D. Aguirre, Movva, R., Schreiber, V., Yang, Y., Proctor, M., Wang, R., Sheng, Y., Lobb, M., Cuiv, P. O., Duley, J. A., Begun, J. and Florin, T. H. J. (2016). Bacterial activation of thioguanine results in lymphocyte independent improvement in murine colitis. 11th Congress of ECCO - European Crohn’s and Colitis Organisation, Amsterdam, Netherlands, 16-19 March 2016. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjw019.177

Bacterial activation of thioguanine results in lymphocyte independent improvement in murine colitis

2016

Journal Article

Towards an integrated understanding of the therapeutic utility of exclusive enteral nutrition in the treatment of Crohn's disease

O Cuiv, Paraic, Begun, Jake, Keely, Simon, Lewindon, Peter and Morrison, Mark (2016). Towards an integrated understanding of the therapeutic utility of exclusive enteral nutrition in the treatment of Crohn's disease. Food and Function, 7 (4), 1741-1751. doi: 10.1039/C5FO01196E

Towards an integrated understanding of the therapeutic utility of exclusive enteral nutrition in the treatment of Crohn's disease

2016

Conference Publication

Clinical presentation of IBD diagnosed after age 60

Shukla, D., Begun, J. and Florin, T. (2016). Clinical presentation of IBD diagnosed after age 60. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.13522

Clinical presentation of IBD diagnosed after age 60

2016

Conference Publication

Severe bacterial infections with vedolizumab therapy: 3 illustrative cases

Szetoo, S. W., Hume, G., De Cruz, P. and Begun, J. (2016). Severe bacterial infections with vedolizumab therapy: 3 illustrative cases. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.13522

Severe bacterial infections with vedolizumab therapy: 3 illustrative cases

2016

Conference Publication

An inhibitor of Wnt protein production improves host control of Listeria monocytogenes

Tran, T. T., Andrades, M. G., Nguyen, T. T. K., Wyer, O., Kling, J. C., Begun, J. and Blumenthal, A. (2016). An inhibitor of Wnt protein production improves host control of Listeria monocytogenes. ICI 2016 International Congress of Immunology, Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200

An inhibitor of Wnt protein production improves host control of Listeria monocytogenes

2016

Conference Publication

The burden of illness among adolescents and young adults with inflammatory bowel disease

Duffy, K. and Begun, J. (2016). The burden of illness among adolescents and young adults with inflammatory bowel disease. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.13522

The burden of illness among adolescents and young adults with inflammatory bowel disease

2016

Conference Publication

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

Gulhane, M., Lourie, R., Tong, H., Kang, A., Schreiber, V., Magor, G., Denman, S., Begun, J., Florin, T., Perkins, A., O Cuiv, P., Mcguckin, M. and Hasnain, S. Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21–26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

2016

Conference Publication

Alleviation of Acute Drug-Induced Liver Injury Following Acetaminophen Overdose by Therapeutic Blockade of E-Selectin in Preclinical Mouse Model

Oancea, Iulia, Barbier, Valerie, Chee, David, Lourie, Rohan, Movva, Ramya, Proctor, Martina A., Begun, Jakob, Magnani, John L., Florin, Timothy H. and Winkler, Ingrid (2016). Alleviation of Acute Drug-Induced Liver Injury Following Acetaminophen Overdose by Therapeutic Blockade of E-Selectin in Preclinical Mouse Model. 57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(16)33483-7

Alleviation of Acute Drug-Induced Liver Injury Following Acetaminophen Overdose by Therapeutic Blockade of E-Selectin in Preclinical Mouse Model

2016

Conference Publication

The incidence of 30-day adverse events after colonoscopy in an IBD population

An, Y. K., Wong, J., You, I. S., Mortimore, M., Hewett, D. G., Appleyard, M. N. and Begun, J. (2016). The incidence of 30-day adverse events after colonoscopy in an IBD population. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.13522

The incidence of 30-day adverse events after colonoscopy in an IBD population

2016

Conference Publication

Thiopurine Mediated Chemoprevention of Colitis-Associated Colorectal Dysplasia

Jose, Beulah, Lourie, Rohan, Schreiber, Veronika, Florin, Timothy H., Oancea, Iulia and Begun, Jakob (2016). Thiopurine Mediated Chemoprevention of Colitis-Associated Colorectal Dysplasia. 57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American Gastroenterological Association (AGA57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(16)33291-7

Thiopurine Mediated Chemoprevention of Colitis-Associated Colorectal Dysplasia

2015

Conference Publication

Malnutrition and quality of life among inflammatory bowel disease outpatients

Pulley, J., Todd, A., Flatley, C. and Begun, J. (2015). Malnutrition and quality of life among inflammatory bowel disease outpatients. Gastro 2015 GESA‐AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015, Brisbane, QLD Australia, 28 September‐2 October 2015. Richmond, VIC Australia: John Wiley and Sons. doi: 10.1111/jgh.13096

Malnutrition and quality of life among inflammatory bowel disease outpatients

2015

Journal Article

Integrated genomics of crohn's disease risk variant identifies a role for CLEC12A in antibacterial autophagy

Begun, Jakob, Lassen, Kara G., Jijon, Humberto B., Baxt, Leigh A., Goel, Gautam, Heath, Robert J., Ng, Aylwin, Tam, Jenny M., Kuo, Szu-Yu, Villablanca, Eduardo J., Fagbami, Lola, Oosting, Marije, Kumar, Vinod, Schenone, Monica, Carr, Steven A., Joosten, Leo A. B., Vyas, Jatin M., Daly, Mark J., Netea, Mihai G., Brown, Gordon D., Wijmenga, Cisca and Xavier, Ramnik J. (2015). Integrated genomics of crohn's disease risk variant identifies a role for CLEC12A in antibacterial autophagy. Cell Reports, 11 (12), 1905-1918. doi: 10.1016/j.celrep.2015.05.045

Integrated genomics of crohn's disease risk variant identifies a role for CLEC12A in antibacterial autophagy

2015

Journal Article

Enteroliths in a Kock continent ileostomy: case report and review of the literature

Moattar, Hadi, Begun, Jakob and Florin, Timothy (2015). Enteroliths in a Kock continent ileostomy: case report and review of the literature. Endoscopy, 47 (S 01), E200-E201. doi: 10.1055/s-0034-1391302

Enteroliths in a Kock continent ileostomy: case report and review of the literature