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2018

Journal Article

The role of IL-22 in the resolution of sterile and nonsterile inflammation

Alabbas, Saleh Y, Begun, Jakob, Florin, Timothy H and Oancea, Iulia (2018). The role of IL-22 in the resolution of sterile and nonsterile inflammation. Clinical and Translational Immunology, 7 (4) e1017, e1017. doi: 10.1002/cti2.1017

The role of IL-22 in the resolution of sterile and nonsterile inflammation

2018

Journal Article

Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses nuclear factor Kappa B activation in human gut epithelial cells

Ó Cuív, Páraic, Giri, Rabina, Hoedt, Emily C., McGuckin, Michael A., Begun, Jakob and Morrison, Mark (2018). Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses nuclear factor Kappa B activation in human gut epithelial cells. Frontiers in Immunology, 9 (April) 790, 790. doi: 10.3389/fimmu.2018.00790

Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses nuclear factor Kappa B activation in human gut epithelial cells

2018

Journal Article

Gastrointestinal ultrasound in inflammatory bowel disease: an underused resource with potential paradigm-changing application

Bryant, Robert Venning, Friedman, Antony, Wright, Emily Kate, Taylor, Kirstin, Begun, Jakob, Maconi, Giovanni, Maaser, Christian, Novak, Kerri L., Kucharzik, Torsten, Atkinson, Nathan S. S., Asthana, Anil and Gibson, Peter R. (2018). Gastrointestinal ultrasound in inflammatory bowel disease: an underused resource with potential paradigm-changing application. Gut, 67 (5), 973-985. doi: 10.1136/gutjnl-2017-315655

Gastrointestinal ultrasound in inflammatory bowel disease: an underused resource with potential paradigm-changing application

2018

Journal Article

P328 Crohn’s colitis care (CCCare): development and testing of a bespoke cloud-based clinical management system for inflammatory bowel disease (IBD)

Krishnaprasad, K, Walsh, A, Begun, J, Bell, S, Carter, D, Grafton, R, Sechi, A, Sewell, K, McMahon, A, Connor, S, Radford-Smith, G, Andrews, J and Consortium, Crohn's Colitis Cure ANZIBD (2018). P328 Crohn’s colitis care (CCCare): development and testing of a bespoke cloud-based clinical management system for inflammatory bowel disease (IBD). Journal of Crohn's and Colitis, 12 (supplement_1). doi: 10.1093/ecco-jcc/jjx180.455

P328 Crohn’s colitis care (CCCare): development and testing of a bespoke cloud-based clinical management system for inflammatory bowel disease (IBD)

2018

Conference Publication

Positioning biologics-A case-based discussion: Ustekinumab

Begun, Jakob (2018). Positioning biologics-A case-based discussion: Ustekinumab. Personalizing Inflammatory Bowel Disease Treatment, Melbourne, Australia, 17-18 March 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/jgh.14423

Positioning biologics-A case-based discussion: Ustekinumab

2018

Conference Publication

Crohn's colitis care (CCCare): development and testing of a bespoke cloud-based clinical management system for inflammatory bowel disease (IBD)

Krishnaprasad, K., Walsh, A., Begun, J., Bell, S., Carter, D., Grafton, R., Sechi, A., Sewell, K., McMahon, A., Connor, S., Radford-Smith, G. and Andrews, J. (2018). Crohn's colitis care (CCCare): development and testing of a bespoke cloud-based clinical management system for inflammatory bowel disease (IBD). 13th Congress of ECCO, Vienna, Austria, 14-17 February 2018. Oxford, United Kingdom: Oxford University Press.

Crohn's colitis care (CCCare): development and testing of a bespoke cloud-based clinical management system for inflammatory bowel disease (IBD)

2018

Conference Publication

Selectively targeting the gut in inflammatory bowel disease: session four summary

Begun, Jakob (2018). Selectively targeting the gut in inflammatory bowel disease: session four summary. Personalizing Inflammatory Bowel Disease Treatment, Melbourne, Australia, 17-18 March 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/jgh.14430

Selectively targeting the gut in inflammatory bowel disease: session four summary

2017

Journal Article

Review article: consensus statements on therapeutic drug monitoring of anti-tumour necrosis factor therapy in inflammatory bowel diseases

Mitrev, N., Vande Casteele, N., Seow, C. H., Andrews, J. M., Connor, S. J., Moore, G. T., Barclay, M., Begun, J., Bryant, R., Chan, W., Corte, C., Ghaly, S., Lemberg, D. A., Kariyawasam, V., Lewindon, P., Martin, J., Mountifield, R., Radford-Smith, G., Slobodian, P., Sparrow, M., Toong, C., van Langenberg, D., Ward, M. G. and Leong, R. W. (2017). Review article: consensus statements on therapeutic drug monitoring of anti-tumour necrosis factor therapy in inflammatory bowel diseases. Alimentary Pharmacology & Therapeutics, 46 (11-12), 1037-1053. doi: 10.1111/apt.14368

Review article: consensus statements on therapeutic drug monitoring of anti-tumour necrosis factor therapy in inflammatory bowel diseases

2017

Journal Article

Colonic thioguanine pro-drug: investigation of microbiome and novel host metabolism

Florin, Timothy, Movva, Ramya, Begun, Jakob, Duley, John, Oancea, Iulia and O Cuiv, Paraic (2017). Colonic thioguanine pro-drug: investigation of microbiome and novel host metabolism. Gut Microbes, 9 (2), 1-4. doi: 10.1080/19490976.2017.1387343

Colonic thioguanine pro-drug: investigation of microbiome and novel host metabolism

2017

Journal Article

The gut bacterium and pathobiont Bacteroides vulgatus activates NF-κB in a human gut epithelial cell line in a strain and growth phase dependent manner

Cuív, Páraic Ó., de Wouters, Tomas, Giri, Rabina, Mondot, Stanislas, Smith, Wendy J., Blottière, Hervé M., Begun, Jakob and Morrison, Mark (2017). The gut bacterium and pathobiont Bacteroides vulgatus activates NF-κB in a human gut epithelial cell line in a strain and growth phase dependent manner. Anaerobe, 47, 209-217. doi: 10.1016/j.anaerobe.2017.06.002

The gut bacterium and pathobiont Bacteroides vulgatus activates NF-κB in a human gut epithelial cell line in a strain and growth phase dependent manner

2017

Journal Article

Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles

Tyagi, Nisha, De, Ranjit, Begun, Jakob and Popat, Amirali (2017). Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles. International Journal of Pharmaceutics, 518 (1-2), 220-227. doi: 10.1016/j.ijpharm.2016.12.030

Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles

2017

Conference Publication

Factors influencing the need for endoscopic intervention in esophageal meat bolus impaction: a retrospective, multicenter study

Cheng, D., Lee, R., Lee, A., Begun, J. and St John, A. (2017). Factors influencing the need for endoscopic intervention in esophageal meat bolus impaction: a retrospective, multicenter study. Australian Gastroenterology Week: Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20-22 August 2017. Richmond, VIC, Australia: Wiley-Blackwell.

Factors influencing the need for endoscopic intervention in esophageal meat bolus impaction: a retrospective, multicenter study

2017

Conference Publication

Role of anti-inflammatory gut bioactives in the modulation of immune response in Crohn's disease

Giri, R., Cuiv, P. O. and Begun, J. (2017). Role of anti-inflammatory gut bioactives in the modulation of immune response in Crohn's disease. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD Australia, 20–22 August 2017. Richmond, VIC Australia: Wiley.

Role of anti-inflammatory gut bioactives in the modulation of immune response in Crohn's disease

2017

Conference Publication

Subsets of innate lymphoid cells in acute liver injury

Alabbas, S. Y., Mowa, R., Purdon, A. S., Begun, J., Florin, T. H. and Oancea, I. (2017). Subsets of innate lymphoid cells in acute liver injury. Australian Gastroenterology Week: Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20-22 August 2017. HOBOKEN: Wiley-Blackwell.

Subsets of innate lymphoid cells in acute liver injury

2017

Conference Publication

Targeting interleukin-23(p19) secretion from intestinal epithelial cells to improve intestinal barrier integrity in inflammatory bowel disease

Wang, R., Lourie, R., Tong, H., Giri, R., Schreiber, V., Begun, J., Florin, T., McGuckin, M. A. and Hasnain, S. Z. (2017). Targeting interleukin-23(p19) secretion from intestinal epithelial cells to improve intestinal barrier integrity in inflammatory bowel disease. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD Australia, 20–22 August 2017. Richmond, VIC Australia: Wiley.

Targeting interleukin-23(p19) secretion from intestinal epithelial cells to improve intestinal barrier integrity in inflammatory bowel disease

2017

Conference Publication

A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Youth Living with Inflammatory Bowel Disease and Depression

Ewais, T., Begun, J., Barclay, J., Tefay, M. and Tremellen, A. (2017). A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Youth Living with Inflammatory Bowel Disease and Depression. American Psychiatric Association 2017 Annual Meeting, San Diego, 20-24 May 2017. London, United Kingdom: Sage Publications .

A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Youth Living with Inflammatory Bowel Disease and Depression

2017

Conference Publication

Endoscopic balloon dilatation has a high success rate and appears to reduce the need for surgery in patients with stricturing Crohn's disease

Lim, E., Thai, M., Hendy, P., Alchlaihawi, M., Leong, R. and Begun, J. (2017). Endoscopic balloon dilatation has a high success rate and appears to reduce the need for surgery in patients with stricturing Crohn's disease. Australian Gastroenterology Week: Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20-22 August 2017. Richmond, VIC, Australia: Wiley-Blackwell.

Endoscopic balloon dilatation has a high success rate and appears to reduce the need for surgery in patients with stricturing Crohn's disease

2016

Journal Article

The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis

Elshaer, Dana and Begun, Jakob (2016). The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis. Seminars in Cell and Developmental Biology, 61, 51-59. doi: 10.1016/j.semcdb.2016.08.018

The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis

2016

Journal Article

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism

Oancea, I., Movva, R., Das, I., Aguirre de Carcer, D., Schreiber, V., Yang, Y., Purdon, A., Harrington, B., Proctor, M., Wang, R., Sheng, Y., Lobb, M., Lourie, R., Cuiv, P.O., Duley, J.A., Begun, J. and Florin, T.H.J. (2016). Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism. Gut, 66 (1), 59-69. doi: 10.1136/gutjnl-2015-310874

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism

2016

Journal Article

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuiv, Paraic O., McGuckin, Michael A. and Hasnain, Sumaira Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. Scientific Reports, 6 (1) 28990, 28990. doi: 10.1038/srep28990

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22