
Overview
Background
Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR), an Australian National Health and Medical Research Council (NHMRC) Leadership Fellow L2 at The University of Queensland. He is also a Consultant Clinical Pharmacist at the Royal Brisbane and Women’s Hospital and Interim Director of the Herston Infectious Diseases Institute (HeIDI). He is Director of the NHMRC-funded Centre for Research Excellence RESPOND which is based at UQCCR. He is a clinician-scientist with a strong interest in research and his principal research theme is optimization of antimicrobial dosing in the critically ill. Prof Roberts has authored over 650 published papers and book chapters on this topic, has been awarded over $55 million in grants and has supervised >20 PhD students to completion.
Prof Roberts was recognised as Australia’s leading researcher in two separate categories, Critical Care and Communicable Diseases, by the Australian’s 2019 Research Magazine.
He has been invited to present his results at major international conferences in critical care, infectious diseases, pharmacy, nephrology, transplant and safety. He has served on the Critical Review Panel for ATS/IDSA Guidelines of HAP, HCAP and VAP and the Australian Therapeutic Guidelines - Antibiotic and the 2021 Surviving Sepsis Guidelines. He is the Past Chair of the Working Group for Antimicrobial Use in ICU for the European Society of Intensive Care Medicine and an Executive Member of the PK/PD Group (EPASG) within the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
He is Section Editor for the International Journal of Antimicrobial Agents and an Associate Editor of the Journal or Pharmacy Practice and Research, the journal for the Society of Hospital Pharmacists of Australia and an Associate Editor for Pharmacotherapy and Aanesthesiology Pain and Critical Care Medicine journal. He has convened >50 seminars/conferences including being co-convenor for Medicines Management 2013, The National Conference for Society of Hospital Pharmacists of Australia.
He also engages with Industry to perform studies that develop optimised antibiotic dosing regimens that maximise antibiotic efficacy for testing in clinical trials or for use in special patient populations (e.g. critically ill, pneumonia, dialysis).
Availability
- Professor Jason Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours), University of Sydney
- Doctor of Philosophy, The University of Queensland
- Society of Hospital Pharmacists of Australia, Society of Hospital Pharmacists of Australia
Works
Search Professor Jason Roberts’s works on UQ eSpace
2010
Journal Article
Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?
Roberts, Jason A., Hope, William W. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?. International Journal of Antimicrobial Agents, 35 (5), 419-420. doi: 10.1016/j.ijantimicag.2010.01.022
2010
Journal Article
Therapeutic monitoring of vancomycin in adult patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists
Martin, Jennifer H., Norris, Ross, Barras, Michael, Roberts, Jason, Morris, Ray, Doogue, Matthew and Jones, Graham R. D. (2010). Therapeutic monitoring of vancomycin in adult patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Clinical Biochemist Reviews, 31 (1), 21-24.
2010
Journal Article
First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008
2010
Conference Publication
Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients
Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x
2010
Book Chapter
Antibiotic dosing in critically ill patients
Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. Critical Care Update 2009. (pp. 128-142) edited by Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas. Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.
2010
Book Chapter
Drug distribution: is it a more important determinant of drug dosing than clearance?
Ulldemolins, M., Roberts, J. A. and Rello, J. (2010). Drug distribution: is it a more important determinant of drug dosing than clearance?. Intensive care medicine: annual update 2010. (pp. 507-516) Brussels, Belgium: Springer. doi: 10.1007/978-1-4419-5562-3_47
2010
Conference Publication
Assessment of adequacy of loading dose of phenytoin (PTN) in adult intensive care patients using population pharmacokinetics
Putt, M. T., Roberts, J. A., Udy, A. A., Martin, J. H., Jarrett, P., Salmon, N. and Lipman, J. (2010). Assessment of adequacy of loading dose of phenytoin (PTN) in adult intensive care patients using population pharmacokinetics. 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-2001-7
2010
Journal Article
Augmented renal clearance: Implications for antibacterial dosing in the critically Ill
Udy, Andrew A., Roberts, Jason A., Boots, Robert J., Paterson, David L. and Lipman, Jeffrey (2010). Augmented renal clearance: Implications for antibacterial dosing in the critically Ill. Clinical Pharmacokinetics, 49 (1), 1-16. doi: 10.2165/11318140-000000000-00000
2010
Book Chapter
Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance
Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. Yearbook of Intensive Care and Emergency Medicine 2010. (pp. 495-506) edited by J.-L. Vincent. Brussels, Belgium: Springer Verlag. doi: 10.1007/978-3-642-10286-8
2010
Conference Publication
Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients
Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x
2009
Journal Article
Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study
Ranganathan, Dwarakanathan, Varghese, Julie M., Fassett, Robert G., Lipman, Jeffrey, D'Intini, Vincent, Healy, Helen and Roberts, Jason A. (2009). Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study. BMC Nephrology, 10 (1) 42, 1-6. doi: 10.1186/1471-2369-10-42
2009
Journal Article
Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis
Roberts, Jason A., Udy, Andrew A., O'Donoghue, Stephen, Briscoe, Scott, Paterson, David L. and Lipman, Jeffrey (2009). Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis. International Journal of Antimicrobial Agents, 34 (4), 383-384. doi: 10.1016/j.ijantimicag.2009.05.005
2009
Journal Article
Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing
Roberts, JA and Lipman, J (2009). Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing. Journal of Pharmacy Practice and Research, 39 (3), 219-222. doi: 10.1002/j.2055-2335.2009.tb00457.x
2009
Journal Article
Midazolam metabolism: Implications for individualised dosing?
Roberts, Jason A., Coulthard, Mark G., Addison, Russell S., Foot, Carole and Lipman, Jeffrey (2009). Midazolam metabolism: Implications for individualised dosing?. Journal of Pharmacy Practice and Research, 39 (3), 198-201. doi: 10.1002/j.2055-2335.2009.tb00452.x
2009
Journal Article
Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy
Roberts, Jason A. and Lipman, Jeffrey (2009). Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy. Critical Care Medicine, 37 (8), 2491-2492. doi: 10.1097/CCM.0b013e3181aee840
2009
Journal Article
A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics
Roberts, Jason A., Webb, Steven, Paterson, David, Ho, Kwok M. and Lipman, Jeffrey (2009). A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics. Critical Care Medicine, 37 (6), 2071-2078. doi: 10.1097/CCM.0b013e3181a0054d
2009
Journal Article
Pharmacokinetic issues for antibiotics in the critically ill patient
Roberts, Jason A. and Lipman, Jeffrey (2009). Pharmacokinetic issues for antibiotics in the critically ill patient. Critical Care Medicine, 37 (3), 840-851. doi: 10.1097/CCM.0b013e3181961bff
2009
Journal Article
Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?
Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 (3), 926-933. doi: 10.1097/CCM.0b013e3181968e44
2009
Journal Article
Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139
2009
Book Chapter
Avoiding toxicity of antibiotics
Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. Patient safety and quality of care in intensive care medicine. (pp. 291-304) edited by Jean-Daniel Chiche and Leanne M. Aitken. Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jason Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Suitability of ß-lactam and ß-lactamase inhibitor combinations for use in outpatient parenteral antimicrobial therapy
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Principal Advisor
Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Xin Liu, Dr Patty Mitre
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Honorary Professor Luregn Schlapbach
-
Doctor Philosophy
Precision antimicrobial dosing in infected critically ill patients
Principal Advisor
-
Doctor Philosophy
Improving drug therapy for children with sepsis and life-threatening infections
Principal Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Dr Sainath Raman
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Pharmacokinetics of anti-mycobacterial drugs in patients with cystic fibrosis
Principal Advisor
Other advisors: Professor Rachel Thomson, Professor Scott Bell
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
What is the validity of altered dosing approaches for ensuring appropriate antibiotic dosing in the critically ill?
Principal Advisor
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Optimising antibiotic dosing for the treatment and prevention of central nervous system infections
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients.
Associate Advisor
Other advisors: Professor Victoria Eley
-
Doctor Philosophy
Designing and Implementing a Clinician-Led Protocol for Heparinisation Using Optimal Targets- anti Xa vs APTT
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams
Associate Advisor
Other advisors: Dr Fekade Sime
-
Master Philosophy
Designing and implementing a nurse-led electronic medical record (EMR) integrated heparinisation protocol using optimal targets (anti Xa vs APTT)
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
Completed supervision
-
2025
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Dr Fekade Sime
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Dr Hafiz Abdul-Aziz
-
2022
Doctor Philosophy
Microbiological evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum ß-lactamase-producing Escherichia coli
Principal Advisor
Other advisors: Dr Fekade Sime
-
2022
Doctor Philosophy
Evaluation of combination antibiotic regimens for the treatment of multidrug-resistant Acinetobacter baumannii infections
Principal Advisor
Other advisors: Dr Fekade Sime
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Principal Advisor
Other advisors: Professor Kiran Shekar, Dr Hafiz Abdul-Aziz
-
2020
Doctor Philosophy
Optimisation of alternative antibiotic dosing regimens for maximal antibacterial activity and suppression of emergence of resistance
Principal Advisor
Other advisors: Dr Fekade Sime
-
2019
Doctor Philosophy
A pharmacokinetic/pharmacodynamic and clinical outcome evaluation of beta-lactam antibiotic therapeutic drug monitoring in critically ill patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2019
Doctor Philosophy
Study of the disposition of nebulized tobramycin
Principal Advisor
Other advisors: Professor John Fraser, Associate Professor Jeremy Cohen
-
2017
Doctor Philosophy
Improving antibiotic dosing in critically ill Australian Indigenous patients with severe sepsis
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Translating Innovative Pharmacokinetic Sampling Techniques into Improved Antibiotic Dosing Regimens in Critically Ill Patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Dr Christine Staatz, Professor Jeffrey Lipman
-
2015
Master Philosophy
Vancomycin-associated nephrotoxicity in the Critically-Ill
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2015
Doctor Philosophy
ß-lactam antibiotic pharmacokinetics during continuous venovenous haemofiltration in critically ill patients: Continuous infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2024
Doctor Philosophy
Optimising Antibiotic Dosing for Treatment of Nosocomial Central Nervous System Infections in Neurocritical Care Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
Personalising Antimicrobial Therapy in Critically Ill Patients using Bayesian Dosing Software
Associate Advisor
-
2023
Doctor Philosophy
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Associate Advisor
Other advisors: Professor Peter Cabot, Professor Amirali Popat, Dr Fekade Sime, Dr James Robert Falconer
-
2017
Master Philosophy
Improving the quality of prescribing in elderly hospital inpatients: evaluating the effect of a clinical pharmacist on ward rounds
Associate Advisor
Other advisors: Associate Professor William Cottrell
-
2016
Doctor Philosophy
Sick Patients, Starved Circuits and Sticky Drugs: Understanding pharmacokinetics during extracorporeal membrane oxygenation to optimise drug dosing and improve patient outcomes
Associate Advisor
Other advisors: Professor John Fraser
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Improving Antimicrobial Use In Critically Ill Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2014
Doctor Philosophy
Dose optimisation of antibiotics during different forms of renal replacement therapy: focus on tissue and target site antibiotic concentrations
Associate Advisor
Other advisors: Associate Professor Robert Boots, Professor Jeffrey Lipman
-
2012
Master Philosophy
Challenges in management of infections on a burn injury unit.
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Media
Enquiries
Contact Professor Jason Roberts directly for media enquiries about:
- Antibiotics
- Drug dosage
- Therapeutic drug monitoring
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