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Professor Stefan Thor
Professor

Stefan Thor

Email: 
Phone: 
+61 7 336 52684

Overview

Background

BSc in Biology (1988) Umea University, Sweden

PhD in Molecular Biology (1994), Umea University, Sweden. Supervisor: Thomas Edlund

Postdoc, Molecular Neurobiology (1994-1999) Salk Institute, La Jolla, USA. Mentor: John B. Thomas

Assistant Professor (1999-2004), Harvard Medical School, Boston, USA

Professor of Developmental Biology (2004-2019), Linkoping University, Sweden

Professor of Developmental Biology (2019-), University of Queensland, Brisbane, Australia

Member of the Royal Swedish Academy of Sciences (2013-)

Availability

Professor Stefan Thor is:
Available for supervision

Qualifications

  • Doctor of Philosophy, unknown

Works

Search Professor Stefan Thor’s works on UQ eSpace

94 works between 1989 and 2024

81 - 94 of 94 works

1999

Journal Article

A LIM-homeodomain combinatorial code for motor-neuron pathway selection

Thor, Stefan, Andersson, Siv G. E. , Tomlinson, Andrew and Thomas, John B. (1999). A LIM-homeodomain combinatorial code for motor-neuron pathway selection. Nature, 397 (6714), 76-80. doi: 10.1038/16275

A LIM-homeodomain combinatorial code for motor-neuron pathway selection

1998

Journal Article

Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor

Benveniste, R.J., Thor, S., Thomas, J.B. and Taghert, P.H. (1998). Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor. Development, 125 (23), 4757-4765.

Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor

1998

Journal Article

Function and specificity of LIM domains in Drosophila nervous system and wing development

O'Keefe, D.D., Thor, S and Thomas, J.B. (1998). Function and specificity of LIM domains in Drosophila nervous system and wing development. Development, 125 (19), 3915-3923.

Function and specificity of LIM domains in Drosophila nervous system and wing development

1997

Journal Article

The Drosophila islet gene governs axon pathfinding and neurotransmitter identity

Thor, S and Thomas, JB (1997). The Drosophila islet gene governs axon pathfinding and neurotransmitter identity. Neuron, 18 (3), 397-409. doi: 10.1016/S0896-6273(00)81241-6

The Drosophila islet gene governs axon pathfinding and neurotransmitter identity

1995

Journal Article

Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish

Appel, B., Korzh, V., Glasgow, E., Thor, S., Edlund, T., Dawid, I. B. and Eisen, J. S. (1995). Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish. Development, 121 (12), 4117-4125.

Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish

1995

Journal Article

The genetics of brain development: Conserved programs in flies and mice

Thor, Stefan (1995). The genetics of brain development: Conserved programs in flies and mice. Neuron, 15 (5), 975-977. doi: 10.1016/0896-6273(95)90084-5

The genetics of brain development: Conserved programs in flies and mice

1995

Journal Article

Islet expression of Rhombotin and Isl-1 suggests cell type specific exposure of LIM-domain epitopes

Lund, Kaare , Petersen, Jacob S., Jensen, Jan , Blume, Niels , Edlund, Thomas , Thor, Stefan and Madsen, Ole D. (1995). Islet expression of Rhombotin and Isl-1 suggests cell type specific exposure of LIM-domain epitopes. Endocrine, 3 (6), 399-408. doi: 10.1007/BF02935644

Islet expression of Rhombotin and Isl-1 suggests cell type specific exposure of LIM-domain epitopes

1995

Journal Article

Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous

Lundgren, S. E., Callahan, C. A., Thor, S. and Thomas, A. B. (1995). Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous. Development, 121 (6), 1769-1773.

Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous

1993

Journal Article

Zebrafish primary neurons initiate expression of the LIM homeodomain protein Isl-1 at the end of gastrulation

Korzh, V. , Edlund, T. and Thor, S. (1993). Zebrafish primary neurons initiate expression of the LIM homeodomain protein Isl-1 at the end of gastrulation. Development, 118 (2), 417-425.

Zebrafish primary neurons initiate expression of the LIM homeodomain protein Isl-1 at the end of gastrulation

1992

Journal Article

Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1

Ericson, J., Thor, S., Edlund, T., Jessell, T. M. and Yamada, T. (1992). Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science, 256 (5063), 1555-1560. doi: 10.1126/science.1350865

Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1

1991

Journal Article

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat

Thor, Stefan, Ericson, Johan, Brännström, Thomas and Edlund, Thomas (1991). The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat. Neuron, 7 (6), 881-889. doi: 10.1016/0896-6273(91)90334-V

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat

1991

Journal Article

Novel Insulin Promoter- and Enhancer-Binding Proteins That Discriminate between Pancreatic Alpha and Beta Cells

Ohlsson, Helena, Thor, Stefan and Edlund, Thomas (1991). Novel Insulin Promoter- and Enhancer-Binding Proteins That Discriminate between Pancreatic Alpha and Beta Cells. Molecular Endocrinology, 5 (7), 897-904. doi: 10.1210/mend-5-7-897

Novel Insulin Promoter- and Enhancer-Binding Proteins That Discriminate between Pancreatic Alpha and Beta Cells

1990

Journal Article

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain

Karlsson, Olof, Thor, Stefan, Norberg, Torbjörn, Ohlsson, Helena and Edlund, Thomas (1990). Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain. Nature, 344 (6269), 879-882. doi: 10.1038/344879a0

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain

1989

Conference Publication

Cis- and transacting elements regulating insulin gene transcription

Ohlsson, H., Karlsson, O., Norberg, T., Thor, S. and Edlund, T. (1989). Cis- and transacting elements regulating insulin gene transcription. Elsevier Science Publishers B.V..

Cis- and transacting elements regulating insulin gene transcription

Funding

Current funding

  • 2023 - 2026
    What drives the Anterior Expansion of the Central Nervous System?
    ARC Discovery Projects
    Open grant
  • 2023 - 2025
    Developing an in vitro human sleep system
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2024
    What is the common factor driving brain overgrowth in ASD? Investigating the relationship between epigenetic marks neural stem cell proliferation.
    Simons Foundation Autism Research Initiative - Pilot Award
    Open grant
  • 2022 - 2025
    Understanding the generation of hypothalamic sleep neurons
    ARC Discovery Projects
    Open grant

Past funding

  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant

Supervision

Availability

Professor Stefan Thor is:
Available for supervision

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Available projects

  • The role of the hypothalamic neuropeptide Npvf in mouse fertility and sleep-wake behaviours

    The hypothalamic neuropeptide Npvf is expressed by a very small subset of neurons within the hypothalamus. Npvf has been implicated in fertility, seasonal mating behaviour and sleep-wake behaviours, in several different mammalian species, as well as in the zebrafish. But these studies have been based upon correlative experiments, RNAi and peptide injections, and the Npvf gene has hitherto not beek knocked out. we have geneerated a condititional null allele of Npvf. This project aims to address the effect of a null mutation in Npvf upon a set of mouse behaviours.

  • The role of the mouse Tead1/Vgll2 transcription factors in dictating hypothalamic cell fate

    The hypothalamic neuropeptide Npvf is expressed by a very small subset of neurons within the hypothalamus. Npvf has been implicated in fertility, seasonal mating behaviour and sleep-wake behaviours. Using single cell transcriptional profiling, we and others have identified the transcription factors Tead1 and Vgll2 as selectively expressed in Npvf neurons in the mouse hypothalamus. The Tead and Vgll families typically interact and form a complex. We have generated a mouse Tead1 knock-out, and found that the Npvf neurons are missing. The project aims to address the underlying reason for the phenotype. We are also in the process of obtaining the mouse Vgll2 knockout, to be able to compare the effects of this knock-out with that of Tead1.

Supervision history

Current supervision

Completed supervision

Media

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