Overview
Background
Dr Jennifer Borowsky, MBChB, FRCPA (Anatomical and Molecular Pathology), PhD, graduated with a Bachelor of Medicine and Surgery in 2008 and was awarded Fellowship of the Royal Australasian College of Pathologists in Anatomical Pathology in 2016. She completed a fellowship in Gastrointestinal and Liver Pathology at Massachusetts General Hospital and Dana Farber Cancer Institute in Boston in 2017. She concurrently commenced and has completed a PhD in the molecular pathobiology of colorectal cancer and continues to publish in this field through appointments to the Conjoint Gastroenterology Group at the Queensland Institute of Medical Research (QIMR) and national and international collaborations. Jennifer is a Senior Pathologist and co-director of Anatomical Pathology at the Princess Alexandra Hospital as well as Molecular Pathologist at the Royal Brisbane Hospital overseeing molecular sequencing of solid tumours.
Availability
- Dr Jennifer Borowsky is:
- Available for supervision
Qualifications
- Bachelor of Medicine Surgery, University of Otago
- Doctor of Philosophy of Medicine (Research), The University of Queensland
Research impacts
morphological and molecular profiling of colorectal cancer and its precursors to elucidate diagnosis, prognosis, and therapeutic options.
Works
Search Professor Jennifer Borowsky’s works on UQ eSpace
2020
Conference Publication
Prognostic significance of immune cells and their spatial distribution in colorectal cancer determined by computational pathology using hematoxylin & eosin stained sections
Vayrynen, Juha, Lau, Mai Chan, Haruki, Koichiro, Vayrynen, Sara, Costa, Andressa Dias, Borowsky, Jennifer, Zhao, Melissa, Kishikawa, Junko, Gu, Simeng, Da Silva, Annacarolina Fabiana Lucia, Fuchs, Charles, Meyerhardt, Jeffrey, Giannakis, Marios, Ogino, Shuji and Nowak, Jonathan (2020). Prognostic significance of immune cells and their spatial distribution in colorectal cancer determined by computational pathology using hematoxylin & eosin stained sections. 109th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), Los Angeles, CA, United States, 29 February - 5 March 2020. Amsterdam, Netherlands: Elsevier BV. doi: 10.1038/s41379-020-0470-y
2020
Conference Publication
Immune checkpoint inhibitor-associated celiac disease
Shih, Angela, Badran, Yousef, Coromilas, Alexandra, Chen, Jonathan, Kem, Marina, Borowsky, Jennifer, Misdraji, Joseph, Dougan, Michael and Mino-Kenudson, Mari (2020). Immune checkpoint inhibitor-associated celiac disease. USCAP 109th Annual Meeting 2020: Eyes on you, Los Angeles, CA, United States, 29 February - 5 March 2020. Amsterdam, Netherlands: Elsevier BV. doi: 10.1038/s41374-020-0386-7
2020
Conference Publication
Risk Prediction Model Based on Prognostic Factors Beyond Lymph Node Status in Colorectal Cancer Stages II/III: An Integration of Mixed Clinicopathologic Data Using Bayesian Ensemble Trees
Zhao, Melissa, Lau, Mai Chan, Haruki, Koichiro, Vayrynen, Juha, Vayrynen, Sara, Costa, Andressa Dias, Borowsky, Jennifer, Gu, Simeng, Gurjao, Carino, Fujiyoshi, Kenji, Arima, Kota, Hamada, Tsuyoshi, Lennerz, Jochen, Fuchs, Charles, Chan, Andrew, Ng, Kimmie, Wu, Kana, Zhang, Xuehong, Meyerhardt, Jeffrey, Song, Mingyang, Nowak, Jonathan, Giannakis, Marios, Reiko, Nishihara and Ogino, Shuji (2020). Risk Prediction Model Based on Prognostic Factors Beyond Lymph Node Status in Colorectal Cancer Stages II/III: An Integration of Mixed Clinicopathologic Data Using Bayesian Ensemble Trees. 109th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Los Angeles, CA United States, 29 February - 5 March 2020. Amsterdam, Netherlands: Elsevier.
2020
Journal Article
Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer
Kane, Alexandra M., Fennell, Lochlan J., Liu, Cheng, Borowsky, Jennifer, McKeone, Diane M., Bond, Catherine E., Kazakoff, Stephen, Patch, Ann-Marie, Koufariotis, Lambros T., Pearson, John, Waddell, Nicola, Leggett, Barbara A. and Whitehall, Vicki L.J. (2020). Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer. Neoplasia, 22 (2), 120-128. doi: 10.1016/j.neo.2019.12.002
2019
Journal Article
Clinicopathological features of pyloric gland adenomas of the duodenum: a multicentre study of 57 cases
Miller, Gregory C., Kumarasinghe, Marian P., Borowsky, Jennifer, Choi, Won-Tak, Setia, Namrata, Clauditz, Till, Gidwani, Raja, Sufiyan, Wajiha, Lauwers, Gregory Y. and Brown, Ian S. (2019). Clinicopathological features of pyloric gland adenomas of the duodenum: a multicentre study of 57 cases. Histopathology, 76 (3) his.13996, 404-410. doi: 10.1111/his.13996
2019
Conference Publication
Aspirin reduces the incidence of metastatic Braf mutant colorectal cancer in a preclinical trial
Kane, A., Mckeone, D., Liu, C., Borowsky, J., Leggett, B. and Whitehall, V. (2019). Aspirin reduces the incidence of metastatic Braf mutant colorectal cancer in a preclinical trial. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, SA, Australia, 8 – 10 September 2019. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/jgh.14797
2019
Journal Article
Spectrum of gastrointestinal tract pathology in a multicenter cohort of 43 Cowden syndrome patients
Borowsky, Jennifer, Setia, Namrata, Rosty, Christophe, Conrad, Rod, Susman, Rachel, Misdraji, Joseph, Hart, John, Lauwers, Gregory Y. and Brown, Ian S. (2019). Spectrum of gastrointestinal tract pathology in a multicenter cohort of 43 Cowden syndrome patients. Modern Pathology, 32 (12), 1814-1822. doi: 10.1038/s41379-019-0316-7
2019
Journal Article
Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals five distinct subtypes of colorectal adenocarcinomas
Fennell, Lochlan, Dumenil, Troy, Wockner, Leesa, Hartel, Gunter, Nones, Katia, Bond, Catherine, Borowsky, Jennifer, Liu, Cheng, McKeone, Diane, Bowdler, Lisa, Montgomery, Grant, Klein, Kerenaftali, Hoffmann, Isabell, Patch, Ann-Marie, Kazakoff, Stephen, Pearson, John, Waddell, Nicola, Wirapati, Pratyaksha, Lochhead, Paul, Imamura, Yu, Ogino, Shuji, Shao, Renfu, Tejpar, Sabine, Leggett, Barbara and Whitehall, Vicki (2019). Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals five distinct subtypes of colorectal adenocarcinomas. Cellular and Molecular Gastroenterology and Hepatology, 8 (2), 269-290. doi: 10.1016/j.jcmgh.2019.04.002
2019
Conference Publication
Fusobacterium nucleatum levels correlate with specific immune cell subtypes in the colorectal cancer microenvironment
Ogino, Shuji, Borowsky, Jennifer, Da Silva, Annacarolina Fabiana Lucia, Costa, Andressa Dias, Felt, Kristen, Lau, Mai Chan, Zhao, Melissa, Haruki, Koichiro, Hamada, Tsuyoshi, Mima, Kosuke, Bullman, Susan, Lennerz, Jochen, Giannakis, Marios, Fuchs, Charles and Nowak, Jonathan (2019). Fusobacterium nucleatum levels correlate with specific immune cell subtypes in the colorectal cancer microenvironment. USCAP 108th Annual Meeting 2019 - Unlocking Your Ingenuity, National Harbor, MD, United States, 16 - 21 March 2019. Amsterdam, Netherlands: Elsevier BV. doi: 10.1038/s41374-019-0213-1
2019
Conference Publication
Quantitative, multiplexed analysis of the colorectal cancer microenvironment reveals prognostic significance for T cell subset densities and spatial distribution
Borowsky, Jennifer, Haruki, Koichiro, Costa, Andressa Dias, Zhao, Melissa, Lau, Mai Chan, Da Silva, Annacarolina Fabiana Lucia, Hamada, Tsuyoshi, Felt, Kristen, Lennerz, Jochen, Fuchs, Charles, Giannakis, Marios, Nowak, Jonathan and Ogino, Shuji (2019). Quantitative, multiplexed analysis of the colorectal cancer microenvironment reveals prognostic significance for T cell subset densities and spatial distribution. 108th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP) - Unlocking Your Ingenuity, National Harbor, MD United States, 16-21 March 2019. Amsterdam, Netherlands: Elsevier.
2019
Conference Publication
Tumor-Immune Partitioning and Clustering (TIPC) reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironment
Lau, Mai Chan, Zhao, Melissa, Borowsky, Jennifer, Costa, Andressa Dias, Da Silva, Annacarolina Fabiana Lucia, Felt, Kristen, Hamada, Tsuyoshi, Lennerz, Jochen, Fuchs, Charles, Ogino, Shuji and Nowak, Jonathan (2019). Tumor-Immune Partitioning and Clustering (TIPC) reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironment. USCAP 108th Annual Meeting 2019 - Unlocking Your Ingenuity, National Harbor, MD, United States, 16 - 21 March 2019. Amsterdam, Netherlands: Elsevier BV. doi: 10.1038/s41374-019-0219-8
2019
Conference Publication
Quantitative, multiplexed analysis of the colorectal cancer microenvironment reveals prognostic significance for T cell subset densities and spatial distribution
Borowsky, Jennifer, Haruki, Koichiro, Costa, Andressa Dias, Zhao, Melissa, Lau, Mai Chan, Da Silva, Annacarolina Fabiana Lucia, Hamada, Tsuyoshi, Felt, Kristen, Lennerz, Jochen, Fuchs, Charles, Giannakis, Marios, Nowak, Jonathan and Ogino, Shuji (2019). Quantitative, multiplexed analysis of the colorectal cancer microenvironment reveals prognostic significance for T cell subset densities and spatial distribution. 108th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP) - Unlocking Your Ingenuity, National Harbor, MD United States, 16-21 March 2019. NEW YORK: NATURE PUBLISHING GROUP.
2019
Conference Publication
Tumor-Immune Partitioning and Clustering (TIPC) reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironment
Lau, Mai Chan, Zhao, Melissa, Borowsky, Jennifer, Costa, Andressa Dias, Da Silva, Annacarolina Fabiana Lucia, Felt, Kristen, Hamada, Tsuyoshi, Lennerz, Jochen, Fuchs, Charles, Ogino, Shuji and Nowak, Jonathan (2019). Tumor-Immune Partitioning and Clustering (TIPC) reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironment. 108th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) - Unlocking Your Ingenuity, National Harbor, MD, United States, 16 - 21 March 2019. Amsterdam, Netherlands: Elsevier BV. doi: 10.1038/s41379-019-0232-x
2019
Conference Publication
Fusobacterium nucleatum Levels Correlate with Specific Immune Cell Subtypes in the Colorectal Cancer Microenvironment
Ogino, Shuji, Borowsky, Jennifer, Da Silva, Annacarolina Fabiana Lucia, Costa, Andressa Dias, Felt, Kristen, Lau, Mai Chan, Zhao, Melissa, Haruki, Koichiro, Hamada, Tsuyoshi, Mima, Kosuke, Bullman, Susan, Lennerz, Jochen, Giannakis, Marios, Fuchs, Charles and Nowak, Jonathan (2019). Fusobacterium nucleatum Levels Correlate with Specific Immune Cell Subtypes in the Colorectal Cancer Microenvironment. 108th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) - Unlocking Your Ingenuity, National Harbor, MD United States, 16-21 March 2019. Amsterdam, Netherlands: Elsevier.
2018
Journal Article
The amount of Bifidobacterium genus in colorectal carcinoma tissue in relation to tumor characteristics and clinical outcome
Kosumi, Keisuke, Hamada, Tsuyoshi, Koh, Hideo, Borowsky, Jennifer, Bullman, Susan, Twombly, Tyler S., Nevo, Daniel, Masugi, Yohei, Liu, Li, da Silva, Annacarolina, Chen, Yang, Du, Chunxia, Gu, Mancang, Li, Chenxi, Li, Wanwan, Liu, Hongli, Shi, Yan, Mima, Kosuke, Song, Mingyang, Nosho, Katsuhiko, Nowak, Jonathan A., Nishihara, Reiko, Baba, Hideo, Zhang, Xuehong, Wu, Kana, Wang, Molin, Huttenhower, Curtis, Garrett, Wendy S., Meyerson, Matthew L. ... Ogino, Shuji (2018). The amount of Bifidobacterium genus in colorectal carcinoma tissue in relation to tumor characteristics and clinical outcome. American Journal of Pathology, 188 (12), 2839-2852. doi: 10.1016/j.ajpath.2018.08.015
2018
Conference Publication
Multiplexed immuno-profiling of the colorectal carcinoma microenvironment using archival human tissue
Borowsky, Jennifer, Nowak, Jonathan A., da Silva, Annacarolina, Hamada, Tsuyoshi, Morikawa, Teppei, Twombly, Tyler S., Nosho, Katsuhiko, Nishihara, Reiko, Lennerz, Jochen K., Giannakis, Marios, Chan, Andrew T., Meyerhardt, Jeffrey A., Fuchs, Charles S. and Ogino, Shuji (2018). Multiplexed immuno-profiling of the colorectal carcinoma microenvironment using archival human tissue. The ASPET Annual Meeting at Experimental Biology 2018, San Diego, CA, United States, 21 - 25 April 2018. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1096/fasebj.2018.32.1_supplement.818.4
2018
Conference Publication
Bifidobacterium genus in colorectal carcinoma tissue in relation to tumor characteristics and patient survival
Borowsky, Jennifer, Kosumi, Keisuke, Hamada, Tsuyoshi, Koh, Hideo, Bullman, Susan, Twombly, Tyler S., Masugi, Yohei, Liu, Li, da Silva, Annacarolina, Chen, Yang, Du, Chunxia, Gu, Mancang, Li, Chenxi, Li, Wanwan, Liu, Hongli, Shi, Yan, Song, Mingyang, Nosho, Katsuhiko and Nowak, Jonathan A. (2018). Bifidobacterium genus in colorectal carcinoma tissue in relation to tumor characteristics and patient survival. The ASPET Annual Meeting at Experimental Biology 2018, San Diego, CA, United States, 21 - 25 April 2018. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1096/fasebj.2018.32.1_supplement.407.3
2018
Conference Publication
Body Mass Index and other anthropomorphic variables in relation to risk of colorectal carcinoma subtypes classified by tumor differentiation status
Borowsky, Jennifer, Hanyuda, Akiko, Nishihara, Reiko, Song, Mingyang, Lennerz, Jochen K., Meyerhardt, Jeffrey A., Chan, Andrew T., Fuchs, Charles S., Giovannucci, Edward L., Nowak, Jonathan A., Hamada, Tsuyoshi and Ogino, Shuji (2018). Body Mass Index and other anthropomorphic variables in relation to risk of colorectal carcinoma subtypes classified by tumor differentiation status. The ASPET Annual Meeting at Experimental Biology 2018, San Diego, CA, United States, 21 - 25 April 2018. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1096/fasebj.2018.32.1_supplement.677.9
2018
Conference Publication
Tumor Nuclear YAP1 Expression Status and Molecular Characteristics in relation to Immune Response to Colorectal Carcinoma
Borowsky, Jennifer, Du, Chunxia, Kosumi, Keisuke, Hamada, Tsuyoshi, Morikawa, Teppei, da Silva, Annacarolina, Nosho, Katsuhiko, Nowak, Jonathan A., Nishihara, Reiko, Lennerz, Jochen K., Giannakis, Marios, Chan, Andrew T., Meyerhardt, Jeffrey A., Fuchs, Charles S. and Ogino, Shuji (2018). Tumor Nuclear YAP1 Expression Status and Molecular Characteristics in relation to Immune Response to Colorectal Carcinoma. Annual Meeting of Amer-Assoc-of-Anatomists (AAA), Amer-Physiol-Soc (APS), Amer-Soc-for-Biochemistry-and-Mol-Biol (ASBMB), Amer-Soc-for-Investigat-Pathol (ASIP), Amer-Soc-for-Pharmacol-and-Experimental-Therapeut (ASPET) on Experimental Biology (EB), San Diego, CA United States, 21-25 April 2018. Hoboken, NJ United States: John Wiley & Sons.
2018
Journal Article
The role of APC in WNT pathway activation in serrated neoplasia
Borowsky, Jennifer, Dumenil, Troy, Bettington, Mark, Pearson, Sally-Ann, Bond, Catherine, Fennell, Lochlan, Liu, Cheng, McKeone, Diane, Rosty, Christophe, Brown, Ian, Walker, Neal, Leggett, Barbara and Whitehall, Vicki (2018). The role of APC in WNT pathway activation in serrated neoplasia. Modern Pathology, 31 (3), 495-504. doi: 10.1038/modpathol.2017.150
Supervision
Availability
- Dr Jennifer Borowsky is:
- Available for supervision
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Media
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