Overview
Background
Professor Andrew Mallett is a Nephrologist with a special interest in inherited kidney disease and nephrogenetics. After graduating from James Cook University (MBBS, 2006) he completed physician training at Mackay Base Hospital, Royal Brisbane and Women's Hospital and Princess Alexandra Hospital (MMed USyd, 2009; AFRACMA 2011; FRACP 2013; FASN 2016). Professor Mallett has undertaken a Churchill Fellowship and been a recurrent Visiting Fellow at Addenbrooke's Hospital (Cambridge, UK) and the Cambridge Institute for Medical Research (University of Cambridge). He has completed a PhD in nephrogenetics collaborating nationally and internationally, and is a Consultant Nephrologist at RBWH, co-leading the statewide Queensland Conjoint Renal Genetics Service. Professor Mallett is National Director of KidGen, the AGHA Renal Genetics Rare Disease Flagship.
Availability
- Dr Andrew Mallett is:
- Available for supervision
- Media expert
Works
Search Professor Andrew Mallett’s works on UQ eSpace
2018
Journal Article
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms
Forbes, Thomas A., Howden, Sara E., Lawlor, Kynan, Phipson, Belinda, Maksimovic, Jovana, Hale, Lorna, Wilson, Sean, Quinlan, Catherine, Ho, Gladys, Holman, Katherine, Bennetts, Bruce, Crawford, Joanna, Trnka, Peter, Oshlack, Alicia, Patel, Chirag, Mallett, Andrew, Simons, Cas and Little, Melissa H. (2018). Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms. American Journal of Human Genetics, 102 (5), 816-831. doi: 10.1016/j.ajhg.2018.03.014
2018
Journal Article
Meeting report of the 2017 KidGen Renal Genetics Symposium
Jayasinghe, Kushani, Quinlan, Cathy, Stark, Zornitza, Patel, Chirag, Sampson, Matthew G., Saleem, Moin and Mallett, Andrew J. (2018). Meeting report of the 2017 KidGen Renal Genetics Symposium. Human Genomics, 12 (1) 5, 1-6. doi: 10.1186/s40246-018-0137-7
2018
Conference Publication
Adult-diagnosed non-syndromic nephronophthesis in Australian families caused by biallelic NPHP4 variants
Hudson, R., Patel, C., Hawley, C., O'Shea, S., Snelling, P., Crawford, J., Simons, C. and Mallett, A. J. (2018). Adult-diagnosed non-syndromic nephronophthesis in Australian families caused by biallelic NPHP4 variants. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8-12 September 2018. Richmond, VIC 3121 Australia: Wiley-Blackwell Publishing Asia.
2018
Conference Publication
Clinical outcomes of parathyroidectomy in chronic kidney disease patients
Jones, S., Hegerty, K., Scuderi, C., Eglington, J., Green, B. and Mallett, A. J. (2018). Clinical outcomes of parathyroidectomy in chronic kidney disease patients. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW Australia, 8-12 September 2018. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
2018
Conference Publication
Micro proteomic profiling in the diagnosis of kidney disease
Raghubar, A., Wang, X., Kassianos, A. J., Ng, M. S., Dave, K. A., Norris, E., Headlam, M. J., Healy, H. G. and Mallett, A. J. (2018). Micro proteomic profiling in the diagnosis of kidney disease. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8–12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.13441
2018
Conference Publication
Assessing the impact of hyperuricaemia, gout and allopurinol treatment on progression of renal function in patients with chronic kidney disease
Jeyaruban, A., Hoy, W. E., Cameron, A., Healy, H. G., Zhang, J. and Mallett, A. J. (2018). Assessing the impact of hyperuricaemia, gout and allopurinol treatment on progression of renal function in patients with chronic kidney disease. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8-12 September 2018. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
2018
Conference Publication
Long-term outcome and treatment practices in distal renal tubular acidosis
Lopez Garcia, Sergio Camilo , Emma, Francesco , Walsh, Stephen , Fila, Marc , Hooman, Nakysa , Marcin, Zaniew , Bertholet‐Thomas, Aurélia , Colussi, Giacomo , Ebner, Kathrin , Levtchenko, Elena , Sharma, Jyoti , Singhal, Jyoti , Soliman, Neveen A. , Ariceta, Gema , Basu, Biswanath, Murer, Luisa , Tasic, Velibor , Tsygin, Alexey , Decramer, Stéphane , Gil-peña, Helena , Koster‐kamphuis, Linda , La Scola, Claudio , Gellermann, Jutta , Konrad, Martin , Lilien, Marc , Francisco, Telma , Tramma, Despoina , Trnka, Peter , Yuksel, Selcuk ... Bockenhauer, Detlef (2018). Long-term outcome and treatment practices in distal renal tubular acidosis. 51st Annual ESPN Meeting, Antalya, Turkey, October 2018. Heidelberg, Germany: Springer. doi: 10.1007/s00467-018-4028-x
2018
Conference Publication
PROPKD score predicts kidney decline in clinical practice amongst Australian patients with autosomal dominant polycystic kidney disease
Chan, S., Patel, C. and Mallett, A. J. (2018). PROPKD score predicts kidney decline in clinical practice amongst Australian patients with autosomal dominant polycystic kidney disease. Australian and New Zealand Society of Nephrology (ANZSN) Annual Scientific Meeting, Sydney, NSW, Australia, 8-12 September 2018. Hoboken, NJ, United States: Wiley.
2018
Conference Publication
Cost-effectiveness in kidney medicine: is cinacalcet superior to parathyroidectomy?
Hegerty, K., Jones, S., Scuderi, C., Eglington, J., Broadbent, T., Zhang, H. and Mallett, A. J. (2018). Cost-effectiveness in kidney medicine: is cinacalcet superior to parathyroidectomy?. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW Australia, 8-12 September 2018. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
2018
Conference Publication
Does the type of intervention for ischaemic heart disease impact on mortality and morbidity in patients with chronic kidney disease?
Jeyaruban, A., Hoy, W. E., Cameron, A., Healy, H. G., Zhang, J. and Mallett, A. J. (2018). Does the type of intervention for ischaemic heart disease impact on mortality and morbidity in patients with chronic kidney disease?. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8-12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell.
2017
Journal Article
The increasing rates of acute interstitial nephritis in Australia: a single centre case series
Wilson, Gregory J., Kark, Adrian L., Francis, Leo P., Hoy, Wendy, Healy, Helen G. and Mallett, Andrew J. (2017). The increasing rates of acute interstitial nephritis in Australia: a single centre case series. BMC Nephrology, 18 (1) 329, 1-8. doi: 10.1186/s12882-017-0747-7
2017
Journal Article
Massively parallel sequencing and targeted exomes in familial kidney disease can diagnose underlying genetic disorders
Mallett, Andrew J., McCarthy, Hugh J., Ho, Gladys, Holman, Katherine, Farnsworth, Elizabeth, Patel, Chirag, Fletcher, Jeffery T., Mallawaarachchi, Amali, Quinlan, Catherine, Bennetts, Bruce and Alexander, Stephen I. (2017). Massively parallel sequencing and targeted exomes in familial kidney disease can diagnose underlying genetic disorders. Kidney International, 92 (6), 1493-1506. doi: 10.1016/j.kint.2017.06.013
2017
Journal Article
Mutations in mitochondrial DNA causing tubulointerstitial kidney disease
Connor, Thomas M., Hoer, Simon, Mallett, Andrew, Gale, Daniel P., Gomez-Duran, Aurora, Posse, Viktor, Antrobus, Robin, Moreno, Pablo, Sciacovelli, Marco, Frezza, Christian, Duff, Jennifer, Sheerin, Neil S., Sayer, John A., Ashcroft, Margaret, Wiesener, Michael S., Hudson, Gavin, Gustafsson, Claes M., Chinnery, Patrick F. and Maxwell, Patrick H. (2017). Mutations in mitochondrial DNA causing tubulointerstitial kidney disease. PLoS Genetics, 13 (3) e1006620, e1006620. doi: 10.1371/journal.pgen.1006620
2017
Journal Article
Recurrent atypical haemolytic uraemic syndrome post kidney transplant due to a CD46 mutation in the setting of SMARCAL1-mediated inherited kidney disease
Chan, Samuel, Mallett, Andrew J., Patel, Chirag, Francis, Ross S., Johnson, David W., Mudge, David W. and Isbel, Nicole M. (2017). Recurrent atypical haemolytic uraemic syndrome post kidney transplant due to a CD46 mutation in the setting of SMARCAL1-mediated inherited kidney disease. Nephrology, 22 (S1), 11-14. doi: 10.1111/nep.12933
2017
Journal Article
Monoclonal gammopathy of renal significance triggering atypical haemolytic uraemic syndrome : MGRS triggering aHUS
Mahmood, Usman, Isbel, Nicole, Mollee, Peter, Mallett, Andrew, Govindarajulu, Sridevi and Francis, Ross (2017). Monoclonal gammopathy of renal significance triggering atypical haemolytic uraemic syndrome : MGRS triggering aHUS. Nephrology, 22 (S1), 15-17. doi: 10.1111/nep.12934
2017
Conference Publication
Paraneoplastic immunoglobulin a nephropathy and associated focal segmental glomerulosclerosis in asymptomatic low volume B-cell lymphoma
Ng, M. S. Y., Francis, L., Pillai, E. and Mallett, A. J. (2017). Paraneoplastic immunoglobulin a nephropathy and associated focal segmental glomerulosclerosis in asymptomatic low volume B-cell lymphoma. Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Darwin, NT, Australia, 4–6 September 2017. Richmond, VIC, Australia: Wiley.
2016
Other Outputs
Genetic diagnostics in genetic renal disease: Methods, applications and therapeutics
Mallett, Andrew (2016). Genetic diagnostics in genetic renal disease: Methods, applications and therapeutics. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/414964
2016
Journal Article
KHA-CARI guideline recommendations for the diagnosis and management of autosomal dominant polycystic kidney disease
Rangan, Gopala K., Alexander, Stephen I., Campbell, Katrina L., Dexter, Mark A. J., Lee, Vincent W., Lopez-Vargas, Pamela, Mai, Jun, Mallett, Andrew, Patel, Chirag, Patel, Manish, Tchan, Michel C., Tong, Allison, Tunnicliffe, David J., Vladica, Philip and Savige, Judy (2016). KHA-CARI guideline recommendations for the diagnosis and management of autosomal dominant polycystic kidney disease. Nephrology, 21 (8), 705-716. doi: 10.1111/nep.12658
2016
Journal Article
Polypoid change of the glomerular basement membrane in a child with steroid resistant nephrotic syndrome and ARHGAP24 mutation: a case report
Francis, Anna, Burke, John, Francis, Leo, McTaggart, Steven and Mallett, Andrew (2016). Polypoid change of the glomerular basement membrane in a child with steroid resistant nephrotic syndrome and ARHGAP24 mutation: a case report. Open Urology & Nephrology Journal, 9 (1), 88-93. doi: 10.2174/1874303X01609010088
2016
Journal Article
A multidisciplinary renal genetics clinic improves patient diagnosis
Mallett, Andrew, Fowles, Lindsay F., McGaughran, Julie, Healy, Helen and Patel, Chirag (2016). A multidisciplinary renal genetics clinic improves patient diagnosis. Medical Journal of Australia, 204 (2), 58-59. doi: 10.5694/mja15.01157
Funding
Current funding
Past funding
Supervision
Availability
- Dr Andrew Mallett is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
The IMPEDE-PKD Clinical Trial - Investigating the repurposing of metformin in ADPKD
Principal Advisor
Other advisors: Professor David Johnson, Dr Christine Staatz, Professor Carmel Hawley, Associate Professor Andrea Viecelli
-
Doctor Philosophy
Establishing the Role of Metformin for Autosomal Dominant Polycystic Kidney Disease Management
Principal Advisor
Other advisors: Professor David Johnson, Dr Christine Staatz, Professor Carmel Hawley, Associate Professor Andrea Viecelli
-
Doctor Philosophy
Sample sub-group algorithm bias analysis for machine learning evaluation in the clinical domain
Associate Advisor
Other advisors: Professor Clair Sullivan, Professor Guido Zuccon, Mr Anton Van Der Vegt, Professor Emma McBryde
-
Doctor Philosophy
Improving patient centred outcomes in kidney transplant recipients
Associate Advisor
Other advisors: Dr Christine Staatz
Completed supervision
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2023
Doctor Philosophy
Defining the cellular milieu within the clear cell renal cell carcinoma microenvironment
Principal Advisor
Other advisors: Dr Andrew Kassianos, Dr Quan Nguyen
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2024
Doctor Philosophy
Improving patient centred outcomes in kidney transplant recipients
Associate Advisor
Other advisors: Dr Christine Staatz
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2022
Doctor Philosophy
Rab GTPase Regulation of Primary Cilia in Renal Epithelium
Associate Advisor
Other advisors: Professor Jennifer Stow
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2022
Master Philosophy
Rab GTPase Regulation of Cell Surface Protrusions
Associate Advisor
Other advisors: Professor Jennifer Stow
Media
Enquiries
Contact Dr Andrew Mallett directly for media enquiries about:
- Alport Syndrome
- clinical genomic
- genetic kidney disease
- genetics
- genomics
- inherited kidney disease
- kidney
- kidney disease
- kidney genetics
- nephrology
- polycystic kidney disease
- renal genetics
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